response to candesartan

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a candesartan stimulus.


regulation of microtubule-based process

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton.


response to asparaginase

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an asparaginase stimulus.


name: branching involved in mammary gland duct morphogenesis

description: The process in which the branching structure of the mammary gland duct is generated and organized. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.


name: cell proliferation involved in pronephros development

description: The multiplication or reproduction of cells, resulting in the expansion of the population in the pronephros.


name: positive regulation of methanophenazine metabolic process

description: Any process that activates or increases the frequency, rate or extent of methanophenazine metabolic process.


name: establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration

description: Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell.


name: positive regulation of spore encystment on host

description: Any process that activates, maintains or increases the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


egg coat formation

description: Construction of an egg coat, a specialized extracellular matrix that surrounds the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development.


category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The series of molecular signals initiated by interleukin-6 binding to a receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


response to norepinephrine

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system.


ascaroside metabolic process

description: The chemical reactions and pathways involving ascaroside.


arginine N-succinyltransferase activity

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Catalysis of the reaction: succinyl-CoA + L-arginine = CoA + N2-succinyl-L-arginine.


sterigmatocystin metabolic process

description: The chemical reactions and pathways involving sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.


name: cardiac endothelial cell differentiation

description: The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac endothelial cell.


name: nucleoside oxidase (hydrogen peroxide-forming) activity

description: Catalysis of the reactions: adenosine + 2 O2 = 9-riburonosyladenine + 2 hydrogen peroxide.


cutin-based cuticle development

description: The process whose specific outcome is the progression of the cutin-based cuticle over time, from its formation to the mature structure. Cutin-based cuticle is an extracellular structure composed of a covalently linked macromolecular scaffold of cutin and a variety of organic solvent-soluble lipids that are collectively termed waxes. Such structures are found on the external face of polysaccharide cell walls in land plants.


name: anaerobic cyclohexane-1-carboxylate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of cyclohexane-1-carboxylate, a alicyclic acid, in the absence of oxygen.


name: positive regulation of platelet-derived growth factor receptor-beta signaling pathway

description: Any process that activates or increases the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway.


megakaryocyte development

description: The process whose specific outcome is the progression of a megakaryocyte cell over time, from its formation to the mature structure. Megakaryocyte development does not include the steps involved in committing a cell to a megakaryocyte fate. A megakaryocyte is a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow.


name: positive regulation of ureter smooth muscle cell differentiation

description: Any process that activates or increases the frequency, rate or extent of ureter smooth muscle cell differentiation.


hydroxyquinol 1,2-dioxygenase activity

description: Catalysis of the reaction: benzene-1,2,4-triol + O2 = 3-hydroxy-cis,cis-muconate + 2 H+.


terpene catabolic process

description: The chemical reactions and pathways resulting in the breakdown of terpenes, any of a large group of hydrocarbons made up of isoprene units.


acetylenic compound metabolic process

description: The chemical reactions and pathways involving an acetylenic compound, any compound which contains a carbon-carbon triple bond (aka C#C).


name: morphogenesis of an epithelial fold involved in embryonic heart tube formation

description: The morphogenetic process in which an epithelial sheet bends along a linear axis, contributing to embryonic heart tube formation.


name: positive regulation of motor neuron apoptotic process

description: Any process that activates or increases the frequency, rate or extent of motor neuron apoptotic process.


oral incubation

description: A parental behavior in which fertilized eggs are taken into the mouth and held until hatching.


chondrocyte activation

description: A change in the morphology or behavior of a chondrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. A chondrocyte is a polymorphic cell that forms cartilage.


pre-mRNA catabolic process

description: The chemical reactions and pathways resulting in the breakdown of the unspliced pre-mRNA (pre-messenger RNA).


glucan 1,6-alpha-glucosidase activity

description: Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in (1->6)-alpha-D-glucans and derived oligosaccharides.


butanediol catabolic process

description: The chemical reactions and pathways resulting in the breakdown of butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3.


positive regulation of strand invasion

description: Any process that increases the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.


name: positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II

description: Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II.


conidium germination

description: The physiological and developmental changes that occur in a conidium or asexual spore following release from dormancy up to the earliest signs of development such as swelling of conidia, adhesion and nuclear decondensation followed by hyphal growth several hours later. In many genera of plant pathogenic fungi (e.g. Magnaporthe, Colletotrichum, Ustilago), swelling of the hyphal tips to form appressorium, metabolic activities including respiration, RNA and protein synthesis and trehalose breakdown and changes in cell wall composition can be detected in conidium germination.


name: regulation of collagen biosynthetic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.


name: thiol-driven fumarate reductase activity

description: Catalysis of the reaction: fumarate + coenzyme M + coenzyme B = succinate + coenzyme M + coenzyme B + heterodisulfide.


name: symbiont-mediated non-specific activation of host T-cells

description: A process by which a symbiont superantigen elicits a strong immune response by activating a large number of T cells in a non-specific manner. Unlike conventional antigens, which activate T cells by interacting with specific receptors on the surface of these cells, superantigens can stimulate T cells by binding to regions outside the antigen-binding site. Superantigens can activate a large proportion of T cells, leading to an exaggerated immune response. This excessive activation can result in the release of a large amount of cytokines such as tumor necrosis factor and interleukin-2. The massive cytokine release can lead to an acute toxic shock, causing symptoms such as fever and organ damage.


name: positive regulation of activated CD4-positive, alpha-beta T cell apoptotic process

description: Any process that activates or increases the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process.


pyrimidine deoxyribonucleotide binding

description: Binding to a pyrimidine deoxyribonucleotide, any compound consisting of a pyrimidine deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.


name: L-methionine secondary active transmembrane transporter activity

description: Enables the transfer of L-methionine from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.


name: determination of left/right asymmetry in nervous system

description: The establishment of the nervous system with respect to the left and right halves.


name: regulation of intracellular cholesterol transport

description: Any process that modulates the frequency, rate or extent of the directed movement of cholesterol within cells.


name: envenomation resulting in blood vessel extracellular matrix damage, causing hemorrhagic damage in another organism

description: A process that begins with venom being forced into an organism by the bite or sting of another organism which causes damage to the extracellular matrix of the blood vessels of the bitten organism, ultimately resulting in hemorrhage in the bitten organism.


name: chondrocyte intercalation involved in growth plate cartilage morphogenesis

description: The orderly movement of a chondrocyte from one site to another that contributes to the shaping of growth plate cartilage in an endochondral bone.


name: inositol heptakisphosphate 5-kinase activity

description: Catalysis of the reaction: ATP + 4-diphospho-1D-myo-inositol (1,2,3,5,6)pentakisphosphate = 4,5-bisdiphosphoinositol-1D-myoinositol (1,2,3,6)tetrakisphosphate, and ATP + 6-diphospho-1D-myo-inositol (1,2,3,4,5)pentakisphosphate = 5,6-bisdiphosphoinositol-1D-myoinositol (1,2,3,4)tetrakisphosphate.


name: monodehydroascorbate reductase (NADH) activity

description: Catalysis of the reaction: NADH + H+ + 2 monodehydroascorbate = NAD+ + 2 ascorbate.


name: protein-arginine omega-N monomethyltransferase activity

description: Catalysis of the addition of a methyl group to either of the unmethylated terminal nitrogen atoms (also called omega nitrogen) in peptidyl-arginine to form an omega-N-G-monomethylated arginine residue. The reaction is S-adenosyl-L-methionine + [protein]-L-arginine = S-adenosyl-L-homocysteine + [protein]-Nomega-methyl-L-arginine.


name: oxidoreductase activity, acting on the CH-NH2 group of donors, with a quinone or similar compound as acceptor

description: Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a quinone or similar compound.


squalene synthase activity

description: Catalysis of the reaction: presqualene diphosphate + NADPH = squalene + NADP+ + diphosphate.


description: Catalysis of the reaction: 1-O-(indol-3-ylacetyl)-beta-D-glucose + H2O = H+ + indole-3-acetate + beta-D-glucose.


7-oxatyphasterol synthase activity

description: Catalysis of the reaction: H+ + typhasterol + NADPH + O2 = 7-oxatyphasterol + NADP + H2O.


MutSalpha complex binding

description: Binding to a MutSalpha mismatch repair complex.


name: regulation of double-strand break repair via nonhomologous end joining

description: Any process that modulates the frequency, rate or extent of double-strand break repair via nonhomologous end joining.


adult visceral muscle development

description: The process whose specific outcome is the progression of the adult visceral muscle over time, from its formation to the mature structure.


nicotianamine metabolic process

description: The chemical reactions and pathways involving nicotianamine, 2(S),3'2(S),3''(S)-N-(N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl)-azetidine-2-carboxylic acid.


description: Catalysis of the reaction: all-trans-beta-carotene + O2 = 2 all-trans-retinal.


description: Catalysis of the reaction: an aromatic amino acid + 2-oxoglutarate = an aromatic oxo acid + L-glutamate.


name: anaerobic catabolism of pairs of amino acids

description: The anaerobic chemical reactions and pathways resulting in the breakdown of amino acids; in these reactions, one amino acid is oxidised (acts as an electron donor) and a different amino acid is reduced (acts as an electron acceptor); oxidation of the electron-donating amino acid yields energy in the form of ATP.


regulation of heat dissipation

description: Any process that modulates the rate or extent of heat dissipation.


response to glucoside

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucoside stimulus.


name: chemokine (C-C motif) ligand 1 production

description: The appearance of chemokine (C-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


hemocyte development

description: The process whose specific outcome is the progression of the hemocyte over time, from its formation to the mature structure. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.


guanidinobutyrase activity

description: Catalysis of the reaction: 4-guanidinobutanoate + H2O = 4-aminobutanoate + urea.


regulation of intracellular transport

description: Any process that modulates the frequency, rate or extent of the directed movement of substances within cells.


mesenchymal stem cell proliferation

description: The multiplication or reproduction of mesenchymal stem cells, resulting in the expansion of a stem cell population. A mesenchymal stem cell, or MSC, is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.


name: zeinoxanthin epsilon hydroxylase activity

description: Catalysis of the reaction: zeinoxanthin + NADPH + O2 + H+ = lutein + NADP+ + H2O. Adds a hydroxyl group to the epsilon ring of the alpha-carotene.


name: regulation of cellular response to transforming growth factor beta stimulus

description: Any process that modulates the frequency, rate or extent of cellular response to transforming growth factor beta stimulus.


name: trimethyluric acid monooxygenase activity

description: Catalysis of the reaction: 1,3,7-trimethyluric acid + O2 + NADH + 3 H+ = 1,3,7-trimethyl-5-hydroxyisourate + NAD + H2O.


kidney mesenchyme morphogenesis

description: The process in which the anatomical structures of a kidney mesenchymal tissue are generated and organized. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney.


name: hematopoietic progenitor cell differentiation

description: The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells.


tetrahydrocorphin metabolic process

description: The chemical reactions and pathways involving tetrahydrocorphins, tetrapyrroles that combine the structural elements of both porphyrins and corrins.


name: negative regulation of ornithine catabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of ornithine catabolic process.


ossification

description: The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance.


histone H2B acetyltransferase activity

description: Catalysis of the reaction: acetyl-CoA + histone H2B L-lysine = CoA + histone H2B N6-acetyl-L-lysine.


pedicel mucilage biosynthetic process

description: The chemical reactions and pathways resulting in the formation of mucilage that occur in the flower stem.


caudal fin morphogenesis

description: The process in which the anatomical structures of the caudal fin are generated and organized. A caudal fin is an unpaired medial fin mounted at the caudal end of the fish, and is the main fin used for propulsion.


name: negative regulation of meiotic joint molecule formation

description: Any process that decreases the frequency, rate or extent of meiotic joint molecule formation. Meiotic joint molecule formation is the conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination.


pyochelin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid).


description: Catalysis of the reaction: H+ + uracil 5-carboxylate = CO2 + uracil.


name: symbiont-mediated perturbation of host opsonization

description: A process in which a symbiont alters or subverts opsonization by the host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


cellular response to starvation

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.


linoleic acid metabolic process

description: The chemical reactions and pathways involving linoleic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2.


L-lysine 4-chlorinase activity

description: Catalysis of the reaction: 2-oxoglutarate + chloride + H+ + L-lysine + O2 = 4-chloro-L-lysine + CO2 + H2O + succinate.


histone H3T6 kinase activity

description: Catalysis of the reaction: histone H3-threonine (position 6) + ATP = histone H3-phosphothreonine (position 6) + ADP. This reaction is the addition of a phosphate group to the threonine residue at position 6 of histone H3.


tyrosine phenol-lyase activity

description: Catalysis of the reaction: L-tyrosine + H2O = NH4 + phenol + pyruvate.


propane-1,3-diamine oxidase activity

description: Catalysis of the reaction: propane-1,3-diamine + H2O + O2 = 3-aminopropanal + NH3 + hydrogen peroxide + H+.


alpha-1,4-mannosyltransferase activity

description: Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->4) linkage.


insulin receptor signaling pathway

description: The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.


name: thiosulfate transmembrane transporter activity

description: Enables the transfer of thiosulfate ions, HS2O3(1-), from one side of a membrane to the other.


name: 9,12-cis-hexadecadienoic acid delta 15 desaturase activity

description: Catalysis of the reaction: (9Z,12Z)-hexadecadienoyl-CoA + O2 + a reduced electron acceptor = 9,12,15-cis-hexadecatrienoyl-CoA + 2 H2O + an oxidized electron acceptor.


description: Catalysis of the reaction: S-substituted L-cysteine + acetyl-CoA = S-substituted N-acetyl-L-cysteine + CoA + H+.


GDP-glucosidase activity

description: Catalysis of the reaction: GDP-D-glucose + H2O = D-glucose + GDP + H+.


regulation of angiogenesis

description: Any process that modulates the frequency, rate or extent of angiogenesis.


name: cellular response to 1-oleoyl-sn-glycerol 3-phosphate

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-oleoyl-sn-glycerol 3-phosphate stimulus.


name: epithelial cell migration involved in distal tubule morphogenesis

description: The orderly movement of epithelial cells within a renal tubule that contributes to distal tubule morphogenesis.


chlorobenzene dioxygenase activity

description: Catalysis of the reaction: 2,3-unsubstituted benzenoid + O2 + NAD(P)H + H+ = 2,3-cis-dihydroxydihydrobenzenoid + NAD(P)+. Substrates include 1,4-dichlorobenzene (forms 3,6-dichloro-cis-1,2-dihydroxycyclohexa-3,5-diene), 1,2,3,4-tetrachlorobenzene (forms cis-chlorobenzene dihydrodiol) and 1,2,4-trichlorobenzene (forms 3,4,6-trichloro-cis-1,2-dihydroxycyclohexa-3,5-diene).


description: Catalysis of the reaction: (R)-5-diphosphomevalonate + ATP = ADP + CO2 + H+ + isopentenyl diphosphate + phosphate.


description: Catalysis of the reaction: 4-guanidinobutanal + H2O + NAD+ = 4-guanidinobutanoate + 2 H+ + NADH.


name: endonucleolytic cleaveage between 4.5S rRNA and 5S rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)

description: Endonucleolytic cleavage between the 5S rRNA and the 4.5S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.


description: Catalysis of the reaction: 2-hydroxy-7-hydroxymethylchromene-2-carboxylate = 2-hydroxy-4-hydroxymethylbenzalpyruvate.


description: The chemical reactions and pathways involving gamma-1,2,3,4,5,6-hexachlorocyclohexane (also known as Lindane), the most common form of hexachlorohexane, a halogenated organic insecticide that has been used worldwide for agriculture and public health.


hydrogen peroxide biosynthetic process

description: The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.


protein deacetylation

description: The removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.


chondroitin 4-sulfotransferase activity

description: Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 4'-sulfate.


hepatic immune response

description: An immune response taking place in the liver.


forebrain neuron development

description: The process whose specific outcome is the progression of a neuron that resides in the forebrain, from its initial commitment to its fate, to the fully functional differentiated cell.


tagatose-6-phosphate kinase activity

description: Catalysis of the reaction: ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate.


vitamin D4 metabolic process

description: The chemical reactions and pathways involving vitamin D4, (3S,5Z,7E)-9,10-secoergosta-5,7,10(19)-trien-3-ol.


name: glucosinolate transmembrane transporter activity

description: Enables the transfer of a glucosinolate across a membrane.


versicolorin B desaturase activity

description: Catalyzes the reaction: versicolorin B + NADPH + O2 = versicolorin A + NADP+ + 2 H2O. Uses heme-thiolate as a co-factor. Involved in the synthesis of aflatoxins in the fungus Aspergillus parasiticus.


description: Catalysis of the reaction: UDP-galactose + N-glycan = galactose-beta-1,3-N-glycan + UDP.


description: Catalysis of the reaction: [oligomeric (1->3)-beta-D-glucosyl](n) + phosphate = [(1->3)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate.


teichuronic acid metabolic process

description: The chemical reactions and pathways involving teichuronic acid, a polymer containing chains of uronic acids and N-acetylglucosamine found in the cell wall, membrane or capsule of Gram-positive bacteria.


sensory perception of sound

description: The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound.


name: brain-derived neurotrophic factor receptor signaling pathway

description: The series of molecular signals generated as a consequence of a brain-derived neurotrophic factor receptor binding to one of its physiological ligands.


name: neural crest-derived cardiac glial cell development

description: The process aimed at the progression of a neural crest-derived cardiac glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.


description: Catalysis of the reaction: 2,3-dihydroxybenzoate + O2 = 2-carboxy-cis,cis-muconate + 2 H+.


name: G-protein gated monoatomic ion channel activity

description: An ion channel activity that is gated by binding of a G-protein beta-gamma dimer.


regulation of ferrochelatase activity

description: Any process that modulates the frequency, rate or extent of ferrochelatase activity; catalysis of the reaction: protoporphyrin + Fe2+ = protoheme + 2 H+.


apolipoprotein receptor activity

description: Combining with an apolipoprotein to initiate a change in cell activity.


lactate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of lactate.


mesoderm structural organization

description: The process that contributes to the act of creating the structural organization of the mesoderm. This process pertains to the physical shaping of a rudimentary structure.


viral tail assembly

description: The aggregation, arrangement and bonding together of a set of components to form a virus tail.


name: negative regulation of vesicle transport along microtubule

description: Any process that stops, prevents or reduces the frequency, rate or extent of vesicle transport along microtubule.


alpha-N-acetylglucosaminidase activity

description: Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides.


name: chemorepulsion of branchiomotor neuron axon in neural tube

description: The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube in response to a repulsive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.


neuron projection arborization

description: The process in which the anatomical structures of a neuron projection are generated and organized into branches. A neuron projection is any process extending from a neural cell, such as axons or dendrites.


name: 3,4-dihydroxy-5-polyprenylbenzoic acid O-methyltransferase activity

description: Catalysis of the reaction: 3,4-dihydroxy-5-polyprenylbenzoic acid + S-adenosyl-L-methionine = 3-methoxy-4-hydroxy-5-polyprenylbenzoic acid + S-adenosyl-L-homocysteine + H+.


name: positive regulation of sevenless signaling pathway

description: Any process that activates or increases the frequency, rate or extent of the sevenless signaling pathway.


selenocysteine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of selenocysteine, an essential component of glutathione peroxidase and some other proteins.


threonine aldolase activity

description: Catalysis of the reaction: L-threonine = glycine + acetaldehyde.


cellular response to hydrogen peroxide

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.


name: response to cell size control checkpoint signaling

description: A process that occurs in response to signals generated as a result of cell size control checkpoint signaling.


regulation of lactation

description: Any process that modulates the frequency, rate or extent of lactation.


regulation of corticosterone secretion

description: Any process that modulates the frequency, rate or extent of corticosterone secretion.


sulfur amino acid biosynthetic process

description: The chemical reactions and pathways resulting in the formation of amino acids containing sulfur, comprising cysteine, methionine and selenocysteine.


name: transcription elongation by mitochondrial RNA polymerase

description: The extension of an RNA molecule after transcription initiation and promoter clearance at mitochondrial promoter by the addition of ribonucleotides catalyzed by a mitchondrial RNA polymerase.


name: symbiont-mediated occlusion of host xylem

description: The process in which an organism reduces the flow of fluid within the host xylem, the tissue in plants that carries water and nutrients up from the roots to the shoot and leaves. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: G protein-coupled opioid receptor signaling pathway

description: A G protein-coupled receptor signaling pathway initiated by an opioid binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.


chloromuconate cycloisomerase activity

description: Catalysis of the reaction: 2-chloro-2,5-dihydro-5-oxofuran-2-acetate = 3-chloro-cis,cis-muconate.


name: positive regulation of ecdysteroid secretion

description: Any process that activates or increases the frequency, rate or extent of the regulated release of ecdysteroid.


name: positive regulation of the force of heart contraction by neuronal epinephrine-norepinephrine

description: Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine released from the nerve endings.


description: Catalysis of the reaction: 4-hydroxybutyraldehyde + H2O = 2 H+ + 2 e- + 4-hydroxybutanoate.


name: temperature compensation of the circadian clock

description: The process in which the circadian clock maintains robust and accurate timing over a broad range of physiological temperatures. The circadian clock is an endogenous 24-h timer found in most eukaryotes and in photosynthetic bacteria. The clock drives rhythms in the physiology, biochemistry, and metabolism of the organisms.


diamine N-acetyltransferase activity

description: Catalysis of the reaction: acetyl-CoA + an alkane-alpha,omega-diamine = CoA + an N-acetyldiamine.


name: negative regulation of interleukin-18-mediated signaling pathway

description: Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-18-mediated signaling pathway.


name: positive regulation of retinal cell programmed cell death

description: Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the retina.


name: malate:sodium symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: malate(out) + Na+(out) = malate(in) + Na+(in).


adrenergic receptor activity

description: Combining with epinephrine or norepinephrine and transmitting the signal across the membrane by activating the alpha-subunit of an associated heterotrimeric G-protein complex.


name: epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification

description: Any process that mediates the transfer of information from an epiblast cell to an extraembryonic ectoderm cell that contributes to the specification of the anterior/posterior axis.


description: Catalysis of the reaction: alpha-L-arabinose 1-phosphate + UTP = UDP-L-arabinose + diphosphate.


ERBB2-ERBB4 signaling pathway

description: The series of molecular signals initiated by binding of a ligand to a ERBB4 receptor on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and ERBB4. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB4.


description: Catalysis of the reaction: 4-coumaryl-CoA + 3-oxooctanoyl-CoA + H2O = 4-coumaroylhexanoylmethane + 2 coenzyme A + carbon dioxide.


name: nuclear polyadenylation-dependent snRNA catabolic process

description: The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a small nuclear RNA (snRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target snRNA.


name: negative regulation of male pigmentation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in males.


name: protein localization to astral microtubule

description: A process in which a protein is transported to, or maintained in, a location within an astral microtubule.


renal absorption

description: A renal system process in which water, ions, glucose and proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686).


siRNA transcription

description: The transcription of a small interfering RNA from an RNA template.


name: regulation of retina development in camera-type eye

description: Any process that modulates the frequency, rate or extent of retina development in camera-type eye.


peptidyl-lysine glutarylation

description: The glutarylation of a lysine residue in a protein.


adaxial/abaxial pattern specification

description: The regionalization process in which differences in cell differentiation along the adaxial/abaxial are generated. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure.


name: all-trans retinoic acid 18-hydroxylase activity

description: Catalysis of the reaction: all-trans-retinoate + O2 + reduced [NADPH--hemoprotein reductase] = all-trans-18-hydroxyretinoate + H+ + H2O + oxidized [NADPH--hemoprotein reductase].


name: negative regulation of cell-glial cell adhesion involved in cerebral cortex lamination

description: The process that results in the release of migrating cells from their interaction with radial glial cells as a component of the process of cerebral cortex glial-mediated radial cell migration.


name: dorsal/ventral lineage restriction, imaginal disc

description: Formation and/or maintenance of a lineage boundary between dorsal and ventral compartments that cells cannot cross, thus separating the populations of cells in each compartment.


name: L-tyrosine biosynthetic process from chorismate via L-arogenate

description: The chemical reactions and pathways resulting in the formation of L-tyrosine from other compounds, including chorismate, via the intermediate L-arogenate.


ureide biosynthetic process

description: The chemical reactions and pathways resulting in the formation of ureide, the organic form of nitrogen in nitrogen fixing and transporting plants, from IMP, which is synthesized de novo during nitrogen fixation by roots.


monocyte aggregation

description: The adhesion of one monocyte to one or more other monocytes via adhesion molecules.


name: positive regulation of tyramine signaling pathway

description: Any process that activates or increases the frequency, rate or extent of tyramine signaling pathway.


name: mitotic DNA replication lagging strand elongation

description: Any lagging strand elongation that is involved in mitotic cell cycle DNA replication.


cell proliferation in midbrain

description: The multiplication or reproduction of cells, resulting in the expansion of a cell population in the midbrain.


description: The chemical reactions and pathways resulting in the formation of sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate.


name: ABC-type carbohydrate transporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of carbohydrates across a membrane.


name: negative regulation of chromosome attachment to the nuclear envelope

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chromosome attachment to the nuclear envelope.


name: ionotropic salty taste receptor activity

description: Enables the transmembrane transfer of an ion by a channel that opens when a soluble salty compound has been bound by the channel complex or one of its constituent parts.


allantoin racemase activity

description: Catalysis of the reaction: (S)-(+)-allantoin = (R)-(-)-allantoin.


name: G protein-coupled receptor kinase activity

description: Catalysis of the reaction: ATP + G protein-coupled receptor = ADP + G protein-coupled receptor phosphate.


acetyl-CoA binding

description: Binding to acetyl-CoA, an acyl-CoA having acetyl as its S-acetyl component.


name: negative regulation of innate immunity memory response

description: Any process that stops, prevents or reduces the frequency, rate or extent of innate immunity memory response.


name: positive regulation of nitric oxide mediated signal transduction

description: Any process that increases the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is The series of molecular signals mediated by the detection of nitric oxide (NO).


peptidyl-threonine acetylation

description: The acetylation of peptidyl-threonine.


peptide butyryltransferase activity

description: Catalysis of the reaction: butyryl-CoA + lysine in peptide = CoA + N-butyryl-lysine-peptide.


description: Catalysis of the hydrolysis of alpha-(1->4)-D-glucosidic linkage in 4-alpha-D-{(1->4)-alpha-D-glucanosyl}n trehalose to yield trehalose and alpha-(1->4)-D-glucan.


name: cell communication by electrical coupling

description: The process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.


reproductive structure development

description: The reproductive developmental process whose specific outcome is the progression of somatic structures that will be used in the process of creating new individuals from one or more parents, from their formation to the mature structures.


methylselenol demethylase activity

description: Catalysis of the reaction: methylselenol + H2O => H2Se + CH3OH.


pectoral fin development

description: The process whose specific outcome is the progression of the pectoral fin over time, from its formation to the mature structure.


name: negative regulation of G1/S transition of mitotic cell cycle

description: Any signaling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle.


determination of affect

description: Any process in which an emotional response is associated with a particular sensory stimulation.


ameboidal-type cell migration

description: Cell migration that is accomplished by extension and retraction of a pseudopodium.


corpora quadrigemina development

description: The progression of the corpora quadrigemina over time, from its formation to the mature structure. The corpora quadrigemina is a part of the midbrain that is made up of the superior and inferior colliculi.


endothelial cell chemotaxis

description: The directed movement of an endothelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).


name: UDP-glucose: N-methylanthranilate glucosyltransferase activity

description: Catalysis of the reaction: N-methylanthranilate + UDP-alpha-D-glucose = N-methylanthraniloyl-beta-D-glucopyranose + UDP.


homeostasis of number of meristem cells

description: Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in the meristem.


name: negative regulation of glucose mediated signaling pathway

description: Any process that stops, prevents or reduces the frequency, rate or extent of glucose mediated signaling pathway.


thiamine oxidase activity

description: Catalysis of the reaction: thiamine + 2 O2 = thiamine acetic acid + 2 H2O2.


name: positive regulation of alpha-beta T cell activation

description: Any process that activates or increases the frequency, rate or extent of alpha-beta T cell activation.


name: regulation of response to G2 DNA damage checkpoint signaling

description: Any process that modulates the frequency, rate or extent of response to G2 DNA damage checkpoint signaling.


description: Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-acetyl-D-galactosamine = adenosine 3',5'-bisphosphate + N-acetyl-D-galactosamine 4-sulfate.


name: bile acid transmembrane transporter activity

description: Enables the transfer of bile acid from one side of a membrane to the other. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.


bioactive lipid receptor activity

description: Combining with a bioactive lipid and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. A bioactive lipid is a lipid for which changes in lipid levels result in functional consequences in a variety of cellular processes.


name: regulation of acetylcholine-gated cation channel activity

description: Any process that modulates the frequency, rate or extent of acetylcholine-gated cation channel activity.


name: regulation of iodide transmembrane transport

description: Any process that modulates the frequency, rate or extent of iodide transmembrane transport.


name: negative regulation of antigen processing and presentation of peptide antigen via MHC class I

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I.


name: His-Purkinje system cell differentiation

description: The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the His-Purkinje system. These cells form the fibers regulate cardiac muscle contraction in the ventricles.


description: Catalysis of the reaction: S-adenosyl-L-methionine + xanthotoxol = S-adenosyl-L-homocysteine + xanthotoxin. Xanthotoxol is also known as 8-hydroxyfuranocoumarin and xanthotoxin as 8-methoxyfuranocoumarin.


description: Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) = valerena-4,7(11)-diene + diphosphoric acid.


style development

description: The process whose specific outcome is the progression of the style over time, from its formation to the mature structure. The style is an elongated part of a carpel, or group of fused carpels, and it lies between the ovary and the stigma.


alpha-D-glucan binding

description: Binding to alpha-D-glucan.


name: cell morphogenesis involved in neuron differentiation

description: The process in which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron.


name: branched-chain amino acid catabolic process to alcohol via Ehrlich pathway

description: The chemical reactions and pathways involving the catabolism of branched chain amino acids to produce branched chain alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When a branched chain family amino acid, leucine, isoleucine, or valine, is used as the substrate, 3-methylbutanol, 2-methylbutanol, or 2-methylpropanol, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols.


regulation of fertilization

description: Any process that modulates the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).


description: Catalysis of the reaction: apigenin 7-O-beta-D-glucoside + UDP-alpha-D-glucose = apigenin-7-O-gentiobioside + UDP + H+.


serine hydrolase activity

description: Catalysis of the hydrolysis of a substrate by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).


lacrimal gland development

description: The process whose specific outcome is the progression of the lacrimal gland over time, from its formation to the mature structure. The lacrimal gland produces secretions that lubricate and protect the cornea of the eye.


name: positive regulation of sulfite transport

description: Any process that activates or increases the frequency, rate or extent of sulfite transport.


type I hypersensitivity

description: An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors on mast cells or basophils, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines.


name: positive regulation of monoatomic ion transport

description: Any process that activates or increases the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


glyoxalase III activity

description: Catalysis of the reaction: methylglyoxal + H2O = D-lactate.


name: maintenance of protein complex location in cytoplasm

description: Any process in which a protein complex is maintained in a specific location within the cytoplasm and is prevented from moving elsewhere.


tocopherol cyclase activity

description: Catalysis of the reactions: delta-tocopherol = 2-methyl-6-phytyl-1,4-benzene-1,4-diol, gamma-tocopherol = 2,3-dimethyl-6-phytylbenzene-1,4-diol. delta-tocotrienol = 6-geranylgeranyl-2-methylbenzene-1,4-diol gamma-tocotrienol, and = 6-geranylgeranyl-2,3-dimethylbenzene-1,4-diol.


L-arabinose isomerase activity

description: Catalysis of the reaction: L-arabinose = L-ribulose.


name: positive regulation of Fas signaling pathway

description: Any process that activates or increases the frequency, rate or extent of Fas signaling pathway.


mycofactocin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of the coenzyme mycofactocin, a variably glycosylated small molecule electron pair carrier derived from the C-terminal valine-tyrosine dipeptide of the ribosomally translated precursor peptide MftA.


citrazinate dehydrogenase activity

description: Catalysis of the reaction: citrazinate + H2O = 2,3,6-trihydroxyisonicotinate + 2 H+ + 2 e-.


description: Catalysis of the reaction: indoxyl + UDP-D-glucose = H+ + indican + UDP.


name: detection of electrical stimulus involved in regulation of muscle adaptation

description: The series of events by which an electrical stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation.


parthenolide synthase activity

description: Catalysis of the reaction: costunolide + NADPH + O2 + H+ = parthenolide + NADP(3-) + H2O.


corticotropin receptor activity

description: Combining with corticotropin to initiate a change in cell activity.


advanced glycation end-product binding

description: Binding to advanced glycation end-product.


description: Catalysis of the reaction: N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tri-trans,hepta-cis-undecaprenol + UDP-N-acetyl-D-galactosamine = N-acetyl-D-galactosaminyl-alpha-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tri-trans,hepta-cis-undecaprenol + UDP + H+.


glial cell apoptotic process

description: Any apoptotic process in a glial cell, a non-neuronal cell of the nervous system.


fat-soluble vitamin metabolic process

description: The chemical reactions and pathways involving of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water.


lysosome localization

description: Any process in which a lysosome is transported to, and/or maintained in, a specific location.


description: Catalysis of the reaction: hydroxymethylmethylsilanediol + O2 + 2 H+ + 2 e- = formylmethylsilanediol + 2 H2O.


rhombomere 5 structural organization

description: The process that contributes to creating the structural organization of rhombomere 5. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


name: prephenate dehydrogenase (NAD+) activity

description: Catalysis of the reaction: NAD+ + prephenate = (4-hydroxyphenyl)pyruvate + CO2 + NADH.


name: DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates

description: Catalysis of the reaction: S-adenosyl-L-methionine + CpG (in DNA) = S-adenosyl-L-homocysteine + 5-MeCpG (in DNA).


name: central nervous system neuron differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the central nervous system.


taurine dehydrogenase activity

description: Catalysis of the reaction: A + H2O + taurine = AH(2) + NH4 + sulfoacetaldehyde.


description: Catalysis of the reaction: UDP-galactose + glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose = UDP + glycoprotein-alpha-D-galactosyl-(1,3)-(alpha-L-fucosyl-(1,2))-D-galactose.


phosphinothricin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of phosphinothricin.


description: Catalysis of the reaction: L-tyrosine + pyruvate = (4-hydroxyphenyl)pyruvate + L-alanine.


name: positive regulation of nigerotriose transport

description: Any process that activates or increases the frequency, rate or extent of nigerotriose transport.


steryl-sulfatase activity

description: Catalysis of the reaction: 3-beta-hydroxyandrost-5-en-17-one 3-sulfate + H2O = 3-beta-hydroxyandrost-5-en-17-one + sulfate.


name: peptidyl-proline hydroxylation to 4-hydroxy-L-proline

description: The modification of peptidyl-proline to form 4-hydroxy-L-proline; catalyzed by procollagen-proline,2-oxoglutarate-4-dioxygenase.


uridine phosphorylase activity

description: Catalysis of the reaction: uridine + phosphate = uracil + alpha-D-ribose 1-phosphate.


name: peptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine

description: The synthesis of peptidyl-glycine cholest-5-en-3-beta-ol ester at the carboxy-terminus of autolytically cleaved proteins.


lipid kinase activity

description: Catalysis of the phosphorylation of a simple or complex lipid.


cellular response to cation stress

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cation stress, an increase or decrease in the concentration of positively charged ions in the environment.


3,4-dihydroxybenzoate metabolic process

description: The chemical reactions and pathways involving protocatechuate, the anion of protocatechuic acid (3,4-dihydroxybenzoic acid).


name: positive regulation of stem cell proliferation

description: Any process that activates or increases the frequency, rate or extent of stem cell proliferation.


name: malonate semialdehyde decarboxylase activity

description: Catalysis of the reaction: malonate semialdehyde + H+ = acetaldehyde + CO2.


name: very long-chain fatty acid metabolic process

description: The chemical reactions and pathways involving a very long-chain fatty acid. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons.


name: negative regulation of flagellated sperm motility

description: Any process that stops, prevents or reduces the frequency, rate or extent of flagellated sperm motility.


hemostasis

description: The stopping of bleeding (loss of body fluid) or the arrest of the circulation to an organ or part.


description: Catalysis of the reaction: H2O + NAD+ + 2-aminomuconate semialdehyde = NADH + 2-amino-muconate.


description: Catalysis of the reaction: a phosphatidylethanolamine + a sterol = a sterol ester + a lysophosphatidylethanolamine.


left/right pattern formation

description: The pattern specification process that results in the subdivision of the left/right axis in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment.


left lung morphogenesis

description: The process in which anatomical structures of the left lung are generated and organized.


name: smoothened signaling pathway involved in spinal cord motor neuron cell fate specification

description: The series of molecular signals initiated by binding of a ligand to the transmembrane receptor smoothened in a precursor cell in the spinal cord that contributes to the process of a precursor cell becoming capable of differentiating autonomously into a motor neuron in an environment that is neutral with respect to the developmental pathway.


name: regulation of type B pancreatic cell development

description: Any process that modulates the frequency, rate or extent of pancreatic B cell development.


name: symbiont-mediated perturbation of host intracellular transport

description: A process in which a symbiont alters or subverts the directed movement of substances within the cell of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: regulation of cellotriose catabolic process

description: Any process that modulates the frequency, rate or extent of cellotriose catabolic process.


leaf morphogenesis

description: The process in which the anatomical structures of the leaf are generated and organized.


establishment of lymphocyte polarity

description: The directed orientation of lymphocyte signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with an appropriate activating cell.


name: mesenchymal stem cell proliferation involved in nephron morphogenesis

description: The multiplication or reproduction of mesenchymal stem cells, resulting in the expansion of a stem cell population, that contributes to the shaping of a nephron.


name: vinyl chloride reductive dehalogenase activity

description: Catalysis of the reaction: vinyl chloride + 2 H+ + 2 e- = HCl + ethene.


description: The chemical reactions and pathways involving beta-D-galactofuranose.


name: regulation of early endosome to recycling endosome transport

description: Any process that modulates the frequency, rate or extent of early endosome to recycling endosome transport.


structural constituent of postsynapse

description: The action of a molecule that contributes to the structural integrity of a postsynapse.


rRNA 5'-end processing

description: Any process involved in forming the mature 5' end of an rRNA molecule.


name: acinar cell differentiation involved in salivary gland development

description: The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize an acinar cell of the salivary gland. Acinar cells are protein-secreting cells in the gland.


plastid DNA metabolic process

description: The chemical reactions and pathways involving plastid DNA.


pyramidal neuron development

description: The progression of a pyramidal neuron from its initial formation to its mature state.


regulation of neurotrophin production

description: Any process that modulates the frequency, rate, or extent of production of a neurotrophin.


name: establishment of protein localization to postsynaptic membrane

description: The directed movement of a protein to a specific location in a postsynaptic membrane.


pharynx development

description: The biological process whose specific outcome is the progression of a pharynx from an initial condition to its mature state. The pharynx is the part of the digestive system immediately posterior to the mouth.


name: cyanidin 3-O-p-coumaroylglucoside 2-O''-xylosyltransferase activity

description: Catalysis of the reaction: cyanidin 3-O-(6-O-(E)-4-coumaroyl-beta-D-glucoside) + UDP-alpha-D-xylose = cyanidin 3-O-[2''-O-xylosyl) 6''-O-(p-coumaroyl) glucoside + UDP + H+.


description: Catalysis of the reaction: 2 1-O-sinapoyl-beta-D-glucose = 1,2-di-O-sinapoyl-beta-D-glucose + D-glucose.


cornified envelope assembly

description: The aggregation, arrangement and bonding together of a set of components to form a cornified envelope.


11-oxo-beta-amyrin metabolic process

description: The chemical reactions and pathways involving 11-oxo-beta-amyrin.


name: dorsal spinal cord interneuron anterior axon guidance

description: The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in the anterior direction along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.


butanediol metabolic process

description: The chemical reactions and pathways involving butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3.


name: negative regulation of syringal lignin catabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of syringal lignin catabolic process.


name: regulation of pre-tubular aggregate formation by cell-cell signaling

description: Any process that mediates the transfer of information from one cell to another that modulates the rate, frequency, or extent of pre-tubular aggregate formation. Pre-tubular aggregate formation is the cell adhesion process in which mesenchymal cells adhere to one another in the initial stages of the formation of the pre-tubular aggregate, the earliest recognizable structure of the kidney.


response to alkyl hydroperoxide

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkyl hydroperoxide stimulus. Alkyl hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH, where the substituent is an alkyl group.


allophanate hydrolase activity

description: Catalysis of the reaction: H2O + 3 H+ + urea-1-carboxylate = 2 CO2 + 2 NH4.


name: positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

description: Any process that activates or increases the frequency, rate or extent of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator.


rhodopsin kinase activity

description: Catalysis of the reaction: ATP + rhodopsin = ADP + phosphorhodopsin.


name: regulation of actin cortical patch localization

description: Any process that modulates the localization of an actin cortical patch. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells.


description: Catalysis of the reaction: hydroxidodioxidosulfidosulfate + a reduced thioredoxin = sulfite + hydrogen sulfide + H+ + an oxidized thioredoxin.


name: vesicle targeting, plasma membrane to endosome

description: The process in which vesicles formed at the plasma membrane are directed to specific destinations in endosome membranes, mediated by molecules at the vesicle membrane and target membrane surfaces.


hexitol catabolic process

description: The chemical reactions and pathways resulting in the breakdown of hexitols, any alditol with a chain of six carbon atoms in the molecule.


description: Catalysis of the reaction: CoA + substrate-serine = adenosine 3',5'-bisphosphate + substrate-serine-4'-phosphopantetheine. The transfer of the 4'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form.


serine 2-dehydrogenase activity

description: Catalysis of the reaction: L-serine + H2O + NAD+ = 3-hydroxypyruvate + NH3 + NADH.


leaf development

description: The process whose specific outcome is the progression of the leaf over time, from its formation to the mature structure.


name: negative regulation of cellular response to testosterone stimulus

description: Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to testosterone stimulus.


peroxisome membrane biogenesis

description: The process in which a peroxisome membrane is synthesized, aggregates, and bonds together.


RNA polymerase I promoter clearance

description: A process that mediates the transition from the initiation to the elongation phases of transcription by RNA polymerase I, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors.


mitochondrial tRNA 5'-end processing

description: The process in which the 5' end of a pre-tRNA molecule is converted to that of a mature tRNA in the mitochondrion.


name: peptide cross-linking via 2-(S-L-cysteinyl)-D-allo-threonine

description: The post-translational cross-linking of a cysteine residue to an L-threonine residue to form 2-(S-L-cysteinyl)-D-allo-threonine.


neurotrophin receptor activity

description: Combining with a neurotrophin, any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth, and transmitting the signal to initiate a change in cell activity.


name: regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling

description: Any process that modulates the rate, frequency, or extent of branching involved in salivary gland morphogenesis as a result of signals being generated by the mesenchyme and received and interpreted by the salivary gland epithelium.


name: negative regulation of cellular response to nitrogen starvation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular response to nitrogen starvation.


name: regulation of phytoalexin metabolic process

description: Any process that modulates the frequency, rate or extent of phytoalexin metabolism, the chemical reactions and pathways involving phytoalexins, any of a range of substances produced by plants as part of their defense response.


name: site-specific endodeoxyribonuclease activity, specific for altered base

description: Catalysis of the hydrolysis of ester linkages at specific sites within a deoxyribonucleic acid molecule by creating internal breaks.


name: hydrolase activity, acting on acid sulfur-sulfur bonds

description: Catalysis of the hydrolysis of any acid sulfur-sulfur bond.


name: negative regulation of amine metabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines.


gastric mucosal blood circulation

description: The flow of blood through the gastric mucosa of an animal, enabling the transport of nutrients and the removal of waste products.


steroid metabolic process

description: The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.


proteasome regulatory particle binding

description: Binding to a proteasome regulatory particle.


name: negative regulation of blood circulation

description: Any process that stops, prevents or reduces the frequency, rate or extent of blood circulation.


basement membrane disassembly

description: The controlled breakdown of the basement membrane in the context of a normal process such as imaginal disc eversion.


regulation of phospholipase activity

description: Any process that modulates the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid.


macrolide 2'-kinase activity

description: Catalysis of the reaction: ATP + oleandomycin = ADP + 2 H+ + oleandomycin 2'-O-phosphate.


description: Catalysis of the reaction: H2O + maltose 6'-phosphate = D-glucose + D-glucose 6-phosphate.


2-aminohexanoate transaminase activity

description: Catalysis of the reaction: L-2-aminohexanoate + 2-oxoglutarate = 2-oxohexanoate + L-glutamate.


malate dehydrogenase activity

description: Catalysis of the reversible conversion of pyruvate or oxaloacetate to malate.


name: 23S rRNA (guanine(748)-N(1))-methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + guanine(748) in 23S rRNA = N(1)-methylguanine(748) in 23S rRNA + S-adenosyl-L-homocysteine.


SMAD protein signal transduction

description: An intracellular signaling cassette that starts with the activation of a SMAD protein, leading to the formation of a complex with co-SMADs, which translocates to the nucleus and regulates transcription of specific target genes.


description: Catalysis of the reaction: UDP-alpha-D-glucose + 8-methylthiooctylhydroximate = H+ + 7-methylthioheptyldesulfoglucosinolate + UDP.


rhythmic synaptic transmission

description: Any process involved in the generation of rhythmic, synchronous synaptic inputs in a neural circuit.


GCU codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes a GCU codon.


ecdysone binding

description: Binding to 20-hydroxyecdysone (ecdysone). Ecdysone is an ecdysteroid produced by the prothoracic glands of immature insects and the ovaries of adult females, which stimulates growth and molting.


pyruvate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of pyruvate, 2-oxopropanoate.


2-alkyn-1-ol dehydrogenase activity

description: Catalysis of the reaction: 2-butyne-1,4-diol + NAD+ = 4-hydroxy-2-butynal + H+ + NADH.


name: positive regulation of pancreatic A cell differentiation

description: Any process that activates or increases the frequency, rate or extent of pancreatic A cell differentiation.


leukotriene D4 metabolic process

description: The chemical reactions and pathways involving leukotriene D4.


name: positive regulation of mRNA metabolic process

description: Any process that activates or increases the frequency, rate or extent of mRNA metabolic process.


IgA receptor activity

description: Combining with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


type IV pilus-dependent motility

description: Any process involved in the controlled movement of a bacterial cell which is dependent on the presence of type IV pili. Includes social gliding motility and twitching motility.


2-oxobutyrate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of 2-oxobutyrate, the anion of the organic acid 2-oxobutyric acid, which contains a ketone group on carbon 2.


mRNA 3'-end processing

description: Any process involved in forming the mature 3' end of an mRNA molecule.


uracil metabolic process

description: The chemical reactions and pathways involving uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA.


name: cell proliferation involved in outflow tract morphogenesis

description: The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract.


cellular response to triterpenoid

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triterpenoid stimulus.


name: germarium-derived female germ-line cyst encapsulation

description: Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the germarium. An example of this process is found in Drosophila melanogaster.


detection of pheromone

description: The series of events in which a pheromone stimulus is received by a cell and converted into a molecular signal.


bixin aldehyde dehydrogenase activity

description: Catalysis of the reaction: bixin aldehyde + O2 + NAD = norbixin + NADH + H+.


name: positive regulation of heart rate by circulating epinephrine

description: The process in which the secretion of epinephrine into the bloodstream increases the rate of heart muscle contraction.


name: negative regulation of sorocarp spore cell differentiation

description: Any process that stops, prevents or reduces the frequency, rate or extent of sorocarp spore cell differentiation.


name: D-lactate dehydrogenase (quinone) activity

description: Catalysis of the reaction: (R)-lactate + an ubiquinone = pyruvate + an ubiquinol.


description: Catalysis of the reaction: a cytidine in mRNA + S-adenosyl-L-methionine = a 5-methylcytidine in mRNA + H+ + S-adenosyl-L-homocysteine.


Cdc42 protein signal transduction

description: An intracellular signaling cassette in which a small monomeric GTPase of the Cdc42 subfamily relays a signal.


name: intermediate-density lipoprotein particle binding

description: Binding to a intermediate-density lipoprotein particle, a triglyceride-rich lipoprotein particle that typically contains APOB100, APOE and APOCs and has a density of 1.006-1.019 g/ml and a diameter of between 25-30 nm.


polyphosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a polyphosphate, the anion or salt of polyphosphoric acid.


cytidylate cyclase activity

description: Catalysis of the reaction: CTP = 3',5'-cyclic CMP + diphosphate + H+.


4-nitrophenol 2-monooxygenase activity

description: Catalysis of the reaction: 4-nitrophenol + H+ + NADH + O2 = 4-nitrocatechol + H2O + NAD+.


name: negative regulation of appressorium formation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont appressorium formation.


regulation of ectoderm development

description: Any process that modulates the frequency, rate or extent of ectoderm development.


arabinan metabolic process

description: The chemical reactions and pathways involving arabinan, a polysaccharide composed of arabinose residues.


RITS complex localization

description: Any process in which a RITS complex is transported to, or maintained in, a specific location.


name: protein localization to polar microtubule

description: A process in which a protein is transported to, or maintained in, a location within a polar microtubule.


blood vessel maturation

description: A developmental process, independent of morphogenetic (shape) change, that is required for a blood vessel to attain its fully functional state.


name: stomach pylorus smooth muscle contraction

description: A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the most distal part of the stomach.


name: histone H2AK119 ubiquitin ligase activity

description: Catalysis of the transfer of a ubiquitin molecule to histone 2A at the lysine-119 residue.


response to fluid shear stress

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface.


name: trans-synaptic signaling by carbon monoxide

description: Cell-cell signaling between presynapse and postsynapse mediated by carbon monoxide.


isopentenyl phosphate kinase activity

description: Catalysis of the reaction: isopentenyl phosphate(2-) + ATP(4-) = isopentenyl diphosphate(3-) + ADP(3-).


XMP biosynthetic process

description: The chemical reactions and pathways resulting in the formation of XMP, xanthosine monophosphate.


progression of neural tube closure

description: The process in which the neural folds are fused extending from the initial closure points.


amylin receptor activity

description: Combining with amylin to initiate a change in cell activity.


name: dolichyl diphosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of dolichyl diphosphate, a diphosphorylated dolichol derivative.


terminal region determination

description: Specification of the terminal regions (the two non-segmented ends) of the embryo by the gap genes; exemplified in insects by the actions of huckebein and tailless gene products.


name: regulation of secondary cell wall biogenesis

description: Any process that modulates the frequency, rate or extent of secondary cell wall biogenesis.


collenchyma cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a collenchyma cell. This is a plant cell in which the primary cell walls are unevenly thickened, with most thickening occurring at the cell corners. Cells are living and able to grow, they are elongated, and lignin and secondary walls absent. Collenchyma cells make up collenchyma tissue which acts as a supporting tissue in growing shoots, leaves and petioles. This tissue is often arranged in cortical ribs, as seen prominently in celery and rhubarb petioles.


interleukin-7 production

description: The appearance of interleukin-7 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


beta 2 integrin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of beta 2 integrins, a subfamily of integrins which contain the beta 2 subunit.


name: positive regulation of hematopoietic stem cell migration

description: Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell migration.


name: regulation of bundle of His cell action potential

description: Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell of the bundle of His. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.


name: regulation of lipid transport across blood-brain barrier

description: Any process that modulates the frequency, rate or extent of lipid transport across blood-brain barrier.


deoxycytidine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA.


name: regulation of calcium-independent cell-cell adhesion

description: Any process that modulates the frequency, rate or extent of the attachment of one cell to another cell via adhesion molecules that do not require the presence of calcium for the interaction.


regulation of blood vessel branching

description: Any process that modulates the frequency, rate or extent of blood vessel branching.


description: Catalysis of the reaction: acetyl-CoA + an N-hydroxyarylamine = CoA + an N-acetoxyarylamine.


electron transport chain

description: A process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors.


ribitol metabolic process

description: The chemical reactions and pathways involving ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose. It occurs free in some plants and is a component of riboflavin.


description: Catalysis of the reaction: beta-carotene + O2 = 10'-apo-beta-carotenal + beta-ionone.


description: Catalysis of the reaction: 5-deoxy-D-glucuronate = 5-dehydro-2-deoxy-D-gluconate.


lysine racemase activity

description: Catalysis of the reaction: L-lysine = D-lysine.


name: apical constriction involved in ventral furrow formation

description: The actin-mediated process that results in contraction of the apical end of a polarized columnar epithelial cell, contributing to formation of a ventral indentation (furrow) from the blastoderm epithelium, which is internalized to form a tube in the interior of the embryo, marking the start of gastrulation.


11-oxo-beta-amyrin 30-oxidase activity

description: Catalysis of the reaction: 11-oxo-beta-amyrin + 3 NADPH + 3 O2 + 2 H+ = glycyrrhetinic acid + 3 NADP + 4 H2O.


name: epicardium-derived cell migration to the myocardium

description: The orderly movement of a cell that have undergone an epithelial to mesenchymal transition from the epicardium into the myocardium.


snoRNA localization

description: Any process in which small nucleolar RNA is transported to, or maintained in, a specific location.


5-dehydro-2-deoxygluconokinase activity

description: Catalysis of the reaction: ATP + 5-dehydro-2-deoxy-D-gluconate = ADP + 6-phospho-5-dehydro-2-deoxy-D-gluconate.


apoptotic mitochondrial changes

description: The morphological and physiological alterations undergone by mitochondria during apoptosis.


name: putrescine biosynthetic process from arginine, using agmatinase

description: The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine; in this pathway, arginine is converted to agmatine, and agmatine is converted to putrescine in a single enzymatic step.


description: The chemical reactions and pathways resulting in the breakdown of beta-D-galactofuranose.


name: mesonephric interstitial fibroblast fate commitment

description: The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric interstitial fibroblast.


neural crest cell fate specification

description: The process in which a cell becomes capable of differentiating autonomously into a neural crest cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.


name: positive regulation of nitrogen utilization

description: Any process that activates or increases the frequency, rate or extent of nitrogen utilization.


name: positive regulation of endodermal cell differentiation

description: Any process that activates or increases the frequency, rate or extent of endodermal cell differentiation.


name: positive regulation of austinol biosynthetic process

description: Any process that activates or increases the frequency, rate or extent of austinol biosynthetic process.


glutamate synthase (NADH) activity

description: Catalysis of the reaction: 2 L-glutamate + NAD+ = 2-oxoglutarate + L-glutamine + H+ + NADH.


name: cell surface receptor signaling pathway via STAT

description: An intracellular signal transduction process in which STAT proteins (Signal Transducers and Activators of Transcription) convey a signal to trigger a change in the activity or state of a cell. The STAT cascade begins with receptor activation followed by activation of STAT proteins by kinases. It proceeds through STA dimerization and subsequent nuclear translocation of STAT proteins, and ends with regulation of target gene expression by STAT proteins.


name: tetrapyrrole biosynthetic process from glutamate

description: The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next, from other compounds, including L-glutamate.


name: planar cell polarity pathway involved in cardiac muscle cell fate commitment

description: The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin and contributing to a cardioblast being committed to a cardiac muscle cell fate.


organelle membrane fusion

description: The joining of two lipid bilayers to form a single organelle membrane.


description: Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in dextrans, to remove successive isomaltotriose units from the non-reducing ends of the chains.


name: thioacetamide S-oxide S-oxygenase activity

description: Catalysis of the reaction: thioacetamide S-oxide + O2 + 2 H+ + 2 e- = thioacetamide S,S-dioxide + H2O.


R2/R5 cell differentiation

description: The process in which relatively unspecialized cells acquire the specialized features of R2 and R5 photoreceptors. An example of this process is found in Drosophila melanogaster.


apiose 1-reductase activity

description: Catalysis of the reaction: D-apiitol + NAD+ = D-apiose + H+ + NADH.


name: maturation of LSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)

description: Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8 S rRNA, 2S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.


metal chelating activity

description: The formation of bonds from two or more atoms within the same ligand to a metal atom in complexes in which the metal is part of a ring.


name: regulation of systemic arterial blood pressure by renin-angiotensin

description: The process in which renin-angiotensin modulates the force with which blood passes through the circulatory system.


regulation of mesoderm development

description: Any process that modulates the frequency, rate or extent of mesoderm development.


phosphatidylserine transfer activity

description: Removes phosphatidylserine from the outer leaflet of a donor membrane, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to the outer leaflet of an acceptor membrane.


peptide histaminyltransferase activity

description: Catalysis of the reaction: histamine + L-glutaminyl-[protein] = 5-histaminyl-L-glutamyl-[protein].


name: positive regulation of antigen receptor-mediated signaling pathway

description: Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell.


beta-ketoadipate pathway

description: A pathway of aromatic compound degradation by ortho-cleavage; one branch converts protocatechuate, derived from phenolic compounds, to beta-ketoadipate, and the other branch converts catechol, generated from various aromatic hydrocarbons, amino aromatics, and lignin monomers, also to beta-ketoadipate. Two additional steps accomplish the conversion of beta-ketoadipate to tricarboxylic acid cycle intermediates.


phosphatidylserine floppase activity

description: Catalysis of the movement of phosphatidylserine from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.


name: symbiont-mediated activation of host G protein-coupled receptor signal transduction

description: A process in which a symbiont initiates, promotes, or enhances a G protein-coupled receptor signal transduction pathway in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


tyrocidine metabolic process

description: The chemical reactions and pathways involving tyrocidine.


thromboxane receptor activity

description: Combining with a thromboxane (TXA) to initiate a change in cell activity.


name: histidine catabolic process to hydantoin-5-propionate

description: The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including hydantoin-5-propionate.


name: negative regulation of cytokine-mediated signaling pathway

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the cytokine mediated signaling pathway.


description: The chemical reactions and pathways resulting in the formation of beta-1,2-linked oligomannosides, which are found in fungal cell wall phosphopeptidomannan and phospholipomannan.


foregut morphogenesis

description: The process in which the anatomical structures of the foregut are generated and organized.


neutral lipid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of neutral lipids, lipids only soluble in solvents of very low polarity.


name: pyridoxine transmembrane transporter activity

description: Enables the transfer of pyridoxine from one side of a membrane to the other. Pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.


channel-forming ionophore activity

description: Enables transport of a solute across a membrane. This kind of transporter interacts much more weakly with the solute than the carrier does. It is an aqueous pore that extends across the membrane. It may change from closed to open and back. It transports faster than a carrier. It is always passive.


response to silicon dioxide

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silicon dioxide stimulus.


name: indole-containing compound metabolic process

description: The chemical reactions and pathways involving compounds that contain an indole (2,3-benzopyrrole) skeleton.


description: Catalysis of the reaction: 4'-hydroxyacetophenone + H+ + NADPH + O2 = 4-hydroxyphenyl acetate + H2O + NADP+.


pineal gland development

description: The progression of the pineal gland over time from its initial formation until its mature state. The pineal gland is an endocrine gland that secretes melatonin and is involved in circadian rhythms.


gastrulation with mouth forming second

description: A gastrulation process in which the initial invagination becomes the anus and the mouth forms second.


galactitol metabolic process

description: The chemical reactions and pathways involving galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.


name: regulation of epidermal growth factor receptor signaling pathway

description: Any process that modulates the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.


description: Catalysis of the reaction: rhamnetin + S-adenosyl-L-methionine = ombuin + S-adenosyl-L-homocysteine + H+.


name: L-lysine catabolic process to glutarate, by acetylation

description: The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including glutarate, by acetylation.


(S)-canadine synthase activity

description: Catalysis of the reaction: (S)-tetrahydrocolumbamine + [reduced NADPH--hemoprotein reductase] + O2 -> (S)-canadine + [oxidized NADPH--hemoprotein reductase] + 2 H2O.


description: Catalysis of the reaction: A [sulfatase]-L-cysteine + O2 + 2 a thiol = a [sulfatase]-3-oxo-L-alanine + hydrogen sulfide + a disulfide + H2O.


name: regulation of deoxyribonuclease activity

description: Any process that modulates the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.


description: The chemical reactions and pathways resulting in the formation of dehydro-D-arabinono-1,4-lactone, the gamma-lactone (5R)-3,4-dihydroxy-5-(hydroxymethyl)furan-2(5H)-one.


name: positive regulation of relaxation of cardiac muscle

description: Any process that activates or increases the frequency, rate or extent of relaxation of cardiac muscle.


actinorhodin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of actinorhodin.


toxin sequestering activity

description: Binding to a toxin to prevent it from interacting with other partners or to inhibit its localization to the area of the cell or complex where it is active.


name: malate transmembrane transporter activity

description: Enables the transfer of malate from one side of a membrane to the other. Malate is a chiral hydroxydicarboxylic acid, hydroxybutanedioic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle.


description: Catalysis of the reaction: S-methyl-L-methionine + L-homocysteine = 2 L-methionine + H+.


name: regulation of cleistothecium development

description: Any process that modulates the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.


CAAX-box protein modification

description: The covalent alteration of one or more amino acid residues within the CAAX box region of CAAX box proteins.


name: genital disc anterior/posterior pattern formation

description: The establishment, maintenance and elaboration of the anterior/posterior axis of the genital disc. An anterior and posterior compartment form in each of the three genital disc primoridia (the female genital disc primordium, the male genital disc primordium and the anal primordium).


epithelial cell migration

description: The orderly movement of an epithelial cell from one site to another, often during the development of a multicellular organism.


bone maturation

description: A developmental process, independent of morphogenetic (shape) change, that is required for bone to attain its fully functional state.


name: skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration

description: Any process by which the number of skeletal muscle satellite cells in a skeletal muscle is maintained during muscle regeneration. There are at least three mechanisms by which this is achieved. Skeletal muscle satellite stem cell asymmetric division ensures satellite stem cell numbers are kept constant. Symmetric division of these cells amplifies the number of skeletal muscle satellite stem cells. Some adult skeletal muscle myoblasts (descendants of activated satellite cells) can develop back into quiescent satellite cells, replenishing the overall pool of satellite cells.


tensidol B metabolic process

description: The chemical reactions and pathways involving tensidol B.


name: regulation of retrograde trans-synaptic signaling by trans-synaptic protein complex

description: Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by a trans-synaptic complex.


name: anterior mRNA localization involved in anterior/posterior axis specification

description: Any process in which a mRNA is transported to, and maintained in the anterior portion of the oocyte and/or syncytial embryo contributing to the specification of the anterior/posterior axis.


lobar bronchus epithelium development

description: The biological process whose specific outcome is the progression of a lobar bronchus epithelium from an initial condition to its mature state. This process begins with the formation of the lobar bronchus epithelium and ends with the mature structure. The lobar bronchus epithelium is the tissue made up of epithelial cells that lines the inside of the lobar bronchus.


aerotaxis

description: The directed movement of a motile cell or organism in response to environmental oxygen.


name: lignostilbene alpha beta-dioxygenase activity

description: Catalysis of the reaction: 1,2-bis(4-hydroxy-3-methoxyphenyl)ethylene + O2 = 2 vanillin.


digestive system process

description: A physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.


name: alcohol dehydrogenase (cytochrome c(L)) activity

description: Catalysis of the reaction: 2 [Fe(III)cytochrome cL] + a primary alcohol = 2 [Fe(II)cytochrome cL] + an aldehyde + 2 H+.


name: regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

description: Any process that modulates the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell.


name: regulation of methanofuran metabolic process

description: Any process that modulates the frequency, rate or extent of methanofuran metabolic process.


name: 1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming) activity

description: Catalysis of the reaction: 1,5-anhydro-D-mannitol + NADP+ = 1,5-anhydro-D-fructose + H+ + NADPH.


nose morphogenesis

description: The process in which the anatomical structures of the nose are generated and organized. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity).


name: hydroxymate-containing siderophore biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a siderophore from other compounds, including hydroxamic acid. Hydroxamate is one of the three major chemical groups incorporated into siderophore structures with catechol and a-hydroxycarboxylate, each having a high selectivity for iron(3+).


name: positive regulation of compound eye photoreceptor development

description: Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor development.


anthocyanidin reductase activity

description: Catalysis of the reaction: a flavan-3-ol + 2 NAD(P)+ = an anthocyanidin + 2 NAD(P)H + H+.


dTTP catabolic process

description: The chemical reactions and pathways resulting in the breakdown of dTTP, deoxyribosylthymine triphosphate.


name: cyclic pyranopterin monophosphate synthase activity

description: Catalysis of the reaction: (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic pyranopterin phosphate + diphosphate.


sesquiterpenoid metabolic process

description: The chemical reactions and pathways involving sesquiterpenoid compounds, terpenoids with three isoprene units.


cytokinin dehydrogenase activity

description: Catalysis of the reaction: N6-dimethylallyladenine + acceptor + H2O = adenine + 3-methylbut-2-enal + reduced electron acceptor.


penicillin amidase activity

description: Catalysis of the reaction: penicillin + H2O = a carboxylate + 6-aminopenicillanate.


snoRNP binding

description: Binding to a small nucleolar ribonucleoprotein particle.


name: positive regulation of multicellular organismal process

description: Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.