mammillary axonal complex development

description: The progression of the mammillary axonal complex over time, from its formation to the mature structure. The mammillary axonal complex is formed by the axons from the lateral, medial mammillary and the dorsal premammillary nuclei which share a branching pattern. Every neuron gives off one axonal stem that bifurcates into 2 branches. One of the branches is directed dorsally to the thalamus and another caudally to the midbrain.


name: regulation of epithelial cell migration, open tracheal system

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Any process that modulates the frequency, rate or extent of epithelial cell migration, open tracheal system.


regulation of lipid metabolic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids.


asparaginase activity

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Catalysis of the reaction: L-asparagine + H2O = L-aspartate + NH3.


biotin synthase activity

description: Catalysis of the reaction: 2 S-adenosyl-L-methionine + dethiobiotin + S(2-) = 2 5'-deoxyadenosine + 2 L-methionine + biotin + H+.


primary metabolic process

description: The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.


name: positive regulation of establishment of Sertoli cell barrier

description: Any process that activates or increases the frequency, rate or extent of establishment of Sertoli cell barrier.


name: steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

description: Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative.


cellular response to chlorate

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chlorate stimulus.


response to hydroxyisoflavone

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyisoflavone stimulus.


styrene-oxide isomerase activity

description: Catalysis of the reaction: styrene oxide = phenylacetaldehyde.


name: regulation of hematopoietic stem cell proliferation

description: Any process that modulates the frequency, rate or extent of hematopoietic stem cell proliferation.


name: cytokine production involved in immune response

description: The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus contributing to an immune response, resulting in an increase in its intracellular or extracellular levels.


regulation of T cell apoptotic process

description: Any process that modulates the occurrence or rate of T cell death by apoptotic process.


snRNA stem-loop binding

description: Binding to a stem-loop in a small nuclear RNA (snRNA). An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop.


olfactory bulb tufted cell development

description: The process whose specific outcome is the progression of an olfactory bulb tufted cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.


bacterial-type flagellum assembly

description: The assembly of a bacterial-type flagellum, a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope which functions in cell motility.


name: membrane depolarization during AV node cell action potential

description: The process in which AV node cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.


mitochondrion inheritance

description: The distribution of mitochondria, including the mitochondrial genome, into daughter cells after mitosis or meiosis, mediated by interactions between mitochondria and the cytoskeleton.


name: acireductone dioxygenase (Ni2+-requiring) activity

description: Catalysis of the reaction: 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O2 = 3-(methylthio)propanoate + CO + formate.


intralumenal vesicle formation

description: The invagination of the endosome membrane and resulting formation of a vesicle within the lumen of the endosome.


dibenzofuran metabolic process

description: The chemical reactions and pathways involving dibenzofuran, a substance composed of two benzene rings linked by one ether bond and one carbon-carbon bond. Dibenzofuran is a white crystalline solid created from the production of coal tar and used as an insecticide and an intermediate in the production of other chemicals.


name: cell surface receptor signaling pathway via JAK-STAT

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: A cell surface receptor signaling pathway in which ligand binding causes the receptor to dimerize, bringing the receptor-associated JAKs into close proximity. The JAKs then phosphorylate and activate each other on tyrosine residues.This leads to the activation of associated STAT protein, causing the STATs to dissociate from the receptor, translocate to the nucleus. The pathway ends with regulation of target gene expression by STAT proteins.


15-oxoprostaglandin 13-oxidase activity

description: Catalysis of the reaction: (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprostanoate + NAD(P)+ -> (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprosta-13-enoate + NAD(P)H + H+.


name: inositol trisphosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of inositol trisphosphate, 1,2,3,4,5,6-cyclohexanehexol, with three phosphate groups attached.


glutamate decarboxylation to succinate

description: The chemical reactions and pathways resulting in the formation of succinate from glutamate. Also known as GABA (gamma-aminobutyrate) shunt since it channels glutamate into the TCA cycle bypassing two steps of that cycle. There are three enzymes involved in the GABA shunt: glutamate decarboxylase (GAD), GABA aminotransferase (GABA-TA), and succinate semialdehyde dehydrogenase (SSADH). These three enzymes acting in concert to convert glutamate into succinate. The GABA shunt is predominantly associated with neurotransmission in the mammalian brain. It is also present in nonneuronal cells, in plants, in unicellular eukaryotes, and in prokaryotes.


positive regulation of lactation

description: Any process that activates or increases the frequency, rate or extent of lactation.


name: glomerular epithelial cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a glomerular epithelial cell. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells.


signaling adaptor activity

description: The binding activity of a molecule that brings together two or more molecules in a signaling pathway, permitting those molecules to function in a coordinated way. Adaptor molecules themselves do not have catalytic activity.


name: indolepyruvate ferredoxin oxidoreductase activity

description: Catalysis of the reaction: (indol-3-yl)pyruvate + CoA + oxidized ferredoxin = S-2-(indol-3-yl)acetyl-CoA + CO2 + reduced ferredoxin.


DNA-dependent protein kinase activity

description: DNA dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.


name: positive regulation of membrane permeability

description: Any process that activates or increases the frequency, rate or extent of the passage or uptake of molecules by a membrane.


metanephric proximal tubule development

description: The process whose specific outcome is the progression of the metanephric proximal tubule over time, from its formation to the mature structure. The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology.


insulin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of insulin.


macrophage migration

description: The orderly movement of a macrophage from one site to another.


action potential

description: A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities.


regulation of platelet formation

description: Any process that modulates the frequency, rate or extent of platelet formation.


description: Catalysis of the reaction: 4-hydroxypyridine + O2 + H+ + NADPH = pyridine-3,4-diol + H2O + NADP+.


(S)-cheilanthifoline synthase activity

description: Catalysis of the reaction: (S)-scoulerine + [reduced NADPH--hemoprotein reductase] + O2 = (S)-cheilanthifoline + [oxidized NADPH--hemoprotein reductase] + 2 H2O.


cytoplasmic U snRNP body assembly

description: The aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic U snRNP body.


cellular response to type I interferon

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type I interferon stimulus. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.


intermediate mesoderm formation

description: The process that gives rise to the intermediate mesoderm. This process pertains to the initial formation of the structure from unspecified parts.


xylulose metabolic process

description: The chemical reactions and pathways involving xylulose, the ketopentose threo-2-pentulose.


name: P-type divalent copper transporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cu2+(in) = ADP + phosphate + Cu2+(out).


name: 7-deoxyloganetic acid glucosyltransferase activity

description: Catalysis of the reaction: UDP-alpha-D-glucose + 7-deoxyloganetate = H+ + 7-deoxyloganate + UDP.


name: double membrane vesicle viral factory assembly

description: A process that results in the assembly of a cytoplasmic viral factory consisting of a double-membrane bound vesicle.


protein desumoylation

description: The process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein.


pyoverdine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of the siderochrome pyoverdine.


name: cellular response to actin cytoskeletal stress

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of perturbations or damage to the actin cytoskeleton.


hydroxylamine reductase (NADH) activity

description: Catalysis of the reaction: NH3 + NAD+ + H2O = hydroxylamine + NADH + H+.


succinyl-CoA metabolic process

description: The chemical reactions and pathways involving succinyl-CoA, a compound composed of the monovalent acyl group 3-carboxypropanoyl, derived from succinic acid by loss of one OH group, linked to coenzyme A.


S-methyltransferase activity

description: Catalysis of the transfer of a methyl group to the sulfur atom of an acceptor molecule.


L-galactonolactone oxidase activity

description: Catalysis of the reaction: L-galactono-1,4-lactone + O2 = L-ascorbate + H2O2 + H+.


name: negative regulation of cell adhesion involved in substrate-bound cell migration

description: The disassembly of adhesions at the front and rear of a migrating cell. At the leading edge, adhesion disassembly accompanies the formation of new protrusions; at the cell rear, it promotes tail retraction.


bile acid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of bile acids, any of a group of steroid carboxylic acids occurring in bile.


toxin export channel activity

description: Enables the energy independent passage of toxins, sized less than 1000 Da, across a membrane towards the outside of the cell. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.


name: positive regulation of thymocyte apoptotic process

description: Any process that activates or increases the frequency, rate or extent of thymocyte death by apoptotic process.


name: single-celled organism vegetative growth phase

description: A phase of population growth during which single celled organisms reproduce by budding, fission, or other asexual methods.


spore-bearing structure development

description: The process whose specific outcome is the progression of a spore-bearing structure over time, from its formation to the mature structure. A spore-bearing structure is an anatomical structure that produces new spores.


type 2 immune response

description: An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is orchestrated by the production of particular cytokines, most notably IL-4, IL-5, IL-10, and IL-13, by any of a variety of cell types including T-helper 2 cells, eosinophils, basophils, mast cells, and nuocytes, resulting in enhanced production of certain antibody isotypes and other effects.


name: positive regulation of filamentous growth of a population of unicellular organisms in response to pH

description: Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to pH.


response to L-cysteine

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-cysteine stimulus.


name: positive regulation of cell differentiation

description: Any process that activates or increases the frequency, rate or extent of cell differentiation.


name: maintenance of DNA trinucleotide repeats

description: Any process involved in sustaining the fidelity and copy number of DNA trinucleotide repeats. DNA trinucleotide repeats are naturally occurring runs of three base-pairs.


name: saccharopine dehydrogenase (NADP+, L-lysine-forming) activity

description: Catalysis of the reaction: L-saccharopine + H2O + NADP+ = 2-oxoglutarate + L-lysine + H+ + NADPH.


4-AD 9alpha-hydroxylase activity

description: Catalysis of the reaction: androst-4-ene-3,17-dione + O2 + 2 H+ + 2 e- = 9alpha-hydroxy-4-androstene-3,17-dione + H2O.


cellular response to hormone stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.


description: Catalysis of the reaction: trans-4-(1'-hydroxynaphth-2'-yl)-2-oxobut-3-enoate + H2O = pyruvate + 1-hydroxy-2-naphthaldehyde.


name: protein localization to non-motile cilium

description: A process in which a protein is transported to, or maintained in, a location within a non-motile cilium.


protein tetramerization

description: The formation of a protein tetramer, a macromolecular structure consisting of four noncovalently associated identical or nonidentical subunits.


name: cellular response to glial cell derived neurotrophic factor

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glial cell derived neurotrophic factor stimulus.


name: intermediate mesodermal cell fate commitment

description: The process in which the developmental fate of a cell becomes restricted such that it will develop into an intermediate mesoderm cell.


violaceol I metabolic process

description: The chemical reactions and pathways involving violaceol I.


squalene cyclase activity

description: Catalysis of the reaction: squalene = triterpene.


name: positive regulation of antimicrobial humoral response

description: Any process that activates or increases the frequency, rate, or extent of an antimicrobial humoral response.


FAD biosynthetic process

description: The chemical reactions and pathways resulting in the formation of FAD, the oxidized form of flavin-adenine dinucleotide.


name: negative regulation of Rac protein signal transduction

description: Any process that stops, prevents, or reduces the frequency, rate or extent of Rac protein signal transduction.


calcitonin family receptor activity

description: Combining with any member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)) to initiate a change in cell activity.


description: Catalysis of the reaction: 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol + pyruvate = 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol + L-alanine.


name: oxoglutarate dehydrogenase (NADP+) activity

description: Catalysis of the reaction: 2-oxoglutarate + CoA + NADP+ = CO2 + NADPH + succinyl-CoA.


oxygen metabolic process

description: The chemical reactions and pathways involving diatomic oxygen (O2).


octanoyltransferase activity

description: Catalysis of the transfer of an octanoyl (CH3-[CH2]6-CO-) group to an acceptor molecule.


regulation of response to acetate

description: Any process that modulates the frequency, rate or extent of response to acetate.


riboflavin binding

description: Binding to riboflavin.


description: Catalysis of the reaction: 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine + H+ + NADH + O2 = 1-acyl-2-[(S)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine + H2O + NAD+.


alpha-D-xyloside xylohydrolase

description: Catalysis of the hydrolysis of terminal, non-reducing alpha-D-xylose residues with release of alpha-D-xylose.


polyamine metabolic process

description: The chemical reactions and pathways involving polyamines, any organic compound containing two or more amino groups.


name: cell morphogenesis involved in conjugation with cellular fusion

description: The change in form (cell shape and size) that occurs during sexual reproduction in order to facilitate direct contact between the compatible mating types in organisms that undergo conjugation cellular fusion.


name: generation of catalytic spliceosome for second transesterification step

description: Conformational rearrangement of the spliceosomal complex containing the RNA products from the 1st step of splicing to form the catalytic site for the second step of splicing.


dinucleotide phosphatase activity

description: Catalysis of the reaction: a dinucleotide + H2O = 2 mononucleotides.


violaceol II metabolic process

description: The chemical reactions and pathways involving violaceol II.


protein localization to chloroplast

description: A process in which a protein is transported to, or maintained at, a location in a chloroplast.


translation reinitiation

description: A gene-specific translational control mechanism where the small ribosomal subunit remains attached to the mRNA following termination of translation, then resumes scanning on the same mRNA molecule and initiates again at a downstream start site. Reinitiation depends on de novo recruitment of the ternary complex that is required to recognize the next AUG codon.


name: symbiont-mediated suppression of host inflammasome-mediated signal transduction

description: A process in which a symbiont interferes with, inhibits or stops an inflammasome-mediated signal transduction pathway in the host organism by interfering with its normal execution. The host is defined as the larger of the organisms involved in a symbiotic interaction.


formimidoylaspartate deiminase activity

description: Catalysis of the reaction: N-formimidoyl-L-aspartate + H2O = N-formyl-L-aspartate + NH3.


name: dorsal motor nucleus of vagus nerve formation

description: The process that gives rise to the dorsal motor nucleus of the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts.


name: negative regulation of cholesterol storage

description: Any process that decreases the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.


dopaminergic neuron differentiation

description: The process in which a neuroblast acquires the specialized structural and functional features of a dopaminergic neuron, a neuron that secretes dopamine.


name: negative regulation of blood vessel endothelial cell differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel endothelial cell differentiation.


name: negative regulation of collagen biosynthetic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.


mature follicle stage

description: The stage in oogenesis when the antrum is swollen with follicular fluid. The ovum is ready to erupt from the ovary and is arrested at metaphase of the second meiotic division.


amylopectin maltohydrolase activity

description: Catalysis of the reaction: n H2O + an exposed unphosphorylated, unbranched malto-oligosaccharide tail on amylopectin = amylopectin + maltose.


RNA polymerase II core complex assembly

description: The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase II core complex.


name: negative regulation of neurotrophin TRK receptor signaling pathway

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway.


leukotriene catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.


ubiquitin-like protein ligase activity

description: Catalysis of the transfer of a ubiquitin-like protein (ULP) to a substrate protein via the reaction X-ULP + S = X + S-ULP, where X is either an E2 or E3 enzyme, the X-ULP linkage is a thioester bond, and the S-ULP linkage is an isopeptide bond between the C-terminal glycine of ULP and the epsilon-amino group of lysine residues in the substrate.


description: The chemical reactions and pathways resulting in the formation of omega-hydroxyceramide/acylceramide.


6'-deoxychalcone synthase activity

description: Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA + NADPH + H+ = 4 CoA + isoliquiritigenin + 3 CO2 + NADP+ + H2O.


regulation of NMDA receptor activity

description: Any process that modulates the frequency, rate or extent of N-methyl-D-aspartate selective glutamate receptor activity.


glial cell differentiation

description: The process in which a relatively unspecialized cell acquires the specialized features of a glial cell.


name: rRNA (pseudouridine) methyltransferase activity

description: Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a pseudouridine residue in an rRNA molecule.


name: regulation of sinapate ester biosynthetic process

description: Any process that modulates the frequency, rate or extent of sinapate ester biosynthesis.


glucose catabolic process to butyrate

description: The anaerobic chemical reactions and pathways resulting in the breakdown of glucose, with the production of acetic acid, butyric acid, carbon dioxide (CO2), and dihydrogen; effected by some saccharolytic species of Clostridium, e.g. C. butyricum.


protein K11-linked deubiquitination

description: A protein deubiquitination process in which a K11-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 11 of the ubiquitin monomers, is removed from a protein.


description: Catalysis of the reaction: sn-glycerol 3-phosphate + UDP-D-galactose = 2-(alpha-D-galactosyl)-sn-glycerol 3-phosphate + H+ + UDP.


PR-toxin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of PR-toxin, a bicyclic sesquiterpene belonging to the eremophilane class and acting as a mycotoxin.


glutamate N-acetyltransferase activity

description: Catalysis of the reaction: N(2)-acetyl-L-ornithine + L-glutamate = N-acetyl-L-glutamate + L-ornithine.


aminobenzoate decarboxylase activity

description: Catalysis of the reaction: 4(or 2)-aminobenzoate = aniline + CO2.


name: positive regulation of glutamate receptor signaling pathway

description: Any process that activates or increases the frequency, rate or extent of glutamate receptor signaling pathway.


name: regulation of cardiac cell fate specification

description: Any process that modulates the frequency, rate or extent of cardiac cell fate specification.


bacteriochlorophyll c binding

description: Binding to bacteriochlorophyll c, a chlorophyll of photosynthetic bacteria, for example green sulfur bacteria.


homocitrate synthase activity

description: Catalysis of the reaction: 2-oxoglutarate + acetyl-CoA + H2O = CoA + H+ + homocitrate.


peptidyl-serine modification

description: The modification of peptidyl-serine.


prenylcysteine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of prenylcysteine, 3-methyl-2-buten-1-yl-cysteine, a derivative of the amino acid cysteine formed by the covalent addition of a prenyl residue.


ubiquinone-6 metabolic process

description: The chemical reactions and pathways involving ubiquinone-6. Ubiquinone-6 is a ubiquinone compound having a (2E,6E,10E,14E,18E)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-yl substituent at position 2.


quercetin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of quercetin.


description: Catalysis of the reaction: 1-O-sinapoyl-beta-D-glucose + choline = O-sinapoylcholine + D-glucose.


1-phenanthrol sulfotransferase activity

description: Catalysis of the reaction: 1-phenanthrol + X-SO3(-) = HX + 1-phenanthrylsulfate.


tryptophan biosynthetic process

description: The chemical reactions and pathways resulting in the formation of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid; tryptophan is synthesized from chorismate via anthranilate.


name: positive regulation of synaptic vesicle transport

description: Any process that activates or increases the frequency, rate or extent of synaptic vesicle transport.


ammelide aminohydrolase activity

description: Catalysis of the reaction: ammelide + H2O = cyanuric acid + NH3.


histone H2B ubiquitin ligase activity

description: Catalysis of the transfer of ubiquitin to a histone H2B substrate.


cellotriose binding

description: Binding to cellotriose.


fat cell proliferation

description: The multiplication or reproduction of fat cells by cell division, resulting in the expansion of their population. A fat cell is an animal connective tissue cell specialized for the synthesis and storage of fat.


name: proteinogenic amino acid biosynthetic process

description: The chemical reactions and pathways resulting in the formation of any amino acid that is incorporated into protein naturally by ribosomal translation of mRNA, and that has a specific codon for translation from mRNA to protein.


description: Catalysis of the reaction: (2E,6E,10E)-geranylgeranyl diphosphate + sn-glycerol 1-phosphate = diphosphate + sn-3-O-(geranylgeranyl)glycerol 1-phosphate.


name: commitment of neuronal cell to specific neuron type in forebrain

description: The commitment of neuronal precursor cells to become specialized types of neurons in the forebrain.


estrus

description: The estrous cycle phase in which a female is sexually receptive.


nitric oxide binding

description: Binding to nitric oxide (NO).


photosynthesis, dark reaction

description: A complex cycle of enzyme-mediated reactions which catalyzes the reduction of carbon dioxide to sugar. As well as carbon dioxide the cycle requires reducing power in the form of reduced nicotinamide adenine dinucleotide phosphate (NADP) and chemical energy in the form of adenosine triphosphate (ATP). The reduced NADP (NADPH) and ATP are produced by the 'light' reactions.


name: efflux transmembrane transporter activity

description: Enables the transfer of a specific substance or related group of substances from the inside of the cell to the outside of the cell across a membrane.


indolin-2-one monooxygenase activity

description: Catalysis of the reaction: indolin-2-one + NAD(P)H + H+ + O2 = 3-hydroxyindolin-2-one + NAD(P)+ + H2O.


name: symbiont-mediated cell-to-cell migration in host

description: The directional movement of a symbiont from one host cell to another.


name: voltage-gated calcium channel activity involved in AV node cell action potential

description: Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an AV node cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.


thrombocyte activation

description: A cell activation process that occurs in thrombocytes and consists of a series of progressive, overlapping events including shape change, adhesiveness, and aggregation, which, when carried through to completion, lead to the formation of a stable hemostatic plug. Thrombocytes are nucleated cells found in non-mammalian vertebrates and are involved in hemostasis. They are the functional equivalent of the non-nucleated platelets found in mammals.


name: N-terminal peptidyl-cysteine condensation with pyruvate to form N-pyruvic acid 2-iminyl-L-cysteine

description: The condensation of pyruvate through the 2-oxo group with the N-terminal cysteine of proteins to form the derivative N-pyruvic acid 2-iminyl-L-cysteine.


behavioral response to pain

description: Any process that results in a change in the behavior of an organism as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli.


name: protein localization to actomyosin contractile ring

description: A process in which a protein is transported to, or maintained at, the actomyosin contractile ring.


cuneatus tract morphogenesis

description: Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the dorsal root ganglion towards target cells in the medulla. This axonal process is a member of those that make up the cuneatus tract, a group of axons that are from neurons involved in proprioception from the upper trunk and upper limb.


description: Catalysis of the reaction: UTP + a monosaccharide 1-phosphate = diphosphate + UDP-monosaccharide.


response to trehalose

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose stimulus.


tricarboxylic acid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing three carboxyl (-COOH) groups.


cellular component organization

description: A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.


name: symbiont entry into host cell via disruption of host cell glycocalyx

description: The disruption by a symbiont of host cell capsule to allow entry into the host cell.


regulation of glucagon secretion

description: Any process that modulates the frequency, rate or extent of the regulated release of glucagon.


name: positive regulation of skeletal muscle fiber differentiation

description: Any process that activates or increases the frequency, rate or extent of skeletal muscle fiber differentiation.


nylon metabolic process

description: The chemical reactions and pathways involving nylon, a polymer where the main polymer chain comprises recurring amide groups; these compounds are generally formed from combinations of diamines, diacids and amino acids.


cis-zeatin metabolic process

description: The chemical reactions and pathways involving cis-zeatin, (2Z)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.


beta-glucan metabolic process

description: The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds.


name: positive regulation of retina development in camera-type eye

description: Any process that activates or increases the frequency, rate or extent of retina development in camera-type eye.


name: structural constituent of presynaptic actin cytoskeleton

description: The action of a molecule that contributes to the structural integrity of a presynaptic actin cytoskeleton.


ITP binding

description: Binding to ITP.


hypoblast development

description: The process whose specific outcome is the progression of the hypoblast over time, from its formation to the mature structure. The hypoblast is a tissue formed from the inner cell mass that lies beneath the epiblast.


description: Catalysis of the reaction: phenazine-1-carboxylate + S-adenosyl-L-methionine = 5-methylphenazine-1-carboxylate + S-adenosyl-L-homocysteine.


centrolateral axis specification

description: The establishment, maintenance and elaboration of the centrolateral axis. In plants, this axis is duplicated and runs from the midrib to the margin of the leaf.


positive T cell selection

description: The process of sparing immature T cells which react with self-MHC protein complexes with low affinity levels from apoptotic death.


meiotic telophase I

description: The cell cycle phase which follows anaphase I of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.


central B cell positive selection

description: Any process leading to positive selection of B cells in the bone marrow. Positive selection is the process in which B or T cells are selected to survive based on signaling through their antigen receptors.


methane metabolic process

description: The chemical reactions and pathways involving methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes.


description: Catalysis of the reaction: D-ribose 5-phosphate + ATP + NH4 = 5-phospho-D-ribosylamine + ADP + 2 H+ + phosphate.


name: regulation of establishment of RNA localization to telomere

description: Any process that modulates the frequency, rate or extent of establishment of RNA localization to telomere.


intestinal epithelial cell development

description: The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell of the intestine over time, from its formation to the mature structure.


fructose 5-dehydrogenase activity

description: Catalysis of the reaction: a ubiquinone + keto-D-fructose = 5-dehydro-D-fructose + a ubiquinol.


name: regulation of branching involved in prostate gland morphogenesis

description: Any process that modulates the rate, frequency, or extent of prostate gland branching, the process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem.


regulation of glomerular filtration

description: Any process that modulates the frequency, rate or extent of glomerular filtration. Glomerular filtration is the process in which blood is filtered by the glomerulus into the renal tubule.


trimming of first mannose on A branch

description: The removal of the first alpha-1,2-linked mannose from the A-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum.


name: negative regulation of satellite cell differentiation

description: Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell differentiation.


pantothenate metabolic process

description: The chemical reactions and pathways involving pantothenate, the anion of pantothenic acid, the amide of beta-alanine and pantoic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.


description: Catalysis of the reaction: steviolmonoside + UDP-alpha-D-glucose = rubusoside + UDP + H+.


name: arsenate ion transmembrane transporter activity

description: Enables the transfer of an arsenate ion from one side of a membrane to the other.


peptidyl-threonine autophosphorylation

description: The phosphorylation by a protein of one or more of its own threonine amino acid residues, or a threonine residue on an identical protein.


description: Catalysis of the reaction: xyloglucan + H2O = xyloglucan oligosaccharides. This reaction is the exohydrolysis of 1,4-beta-D-glucosidic linkages in xyloglucan.


peptidyl-cysteine oxidation

description: The oxidation of peptidyl-cysteine to peptidyl-L-cysteine sulfinic acid or peptidyl-L-cysteine sulfenic acid.


name: posterior lateral line neuromast cupula development

description: The process whose specific outcome is the progression of the posterior lateral line neuromast cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter.


histone H3K4 deacetylase activity

description: Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 4) + H2O = histone H3 L-lysine (position 4) + acetate. This reaction represents the removal of an acetyl group from lysine at position 4 of the histone H3 protein.


name: regulation of cytoplasmic pattern recognition receptor signaling pathway

description: Any process that modulates the frequency, rate or extent of a cytoplasmic pattern recognition receptor signaling pathway.


name: (+)-pulegone reductase, (-)-menthone as substrate, activity

description: Catalysis of the reaction: (-)-menthone + NADP+ = (+)-pulegone + NADPH + H+.


delta24(24-1) sterol reductase activity

description: Catalysis of the reaction: ergosterol + NADP+ = ergosta-5,7,22,24(24(1))-tetraen-3beta-ol + H+ + NADPH.


small intestinal transit

description: Migration of ingested material along the length of the small intestine.


name: regulation of formation of radial glial scaffolds

description: Any process that modulates the frequency, rate or extent of the formation of radial glial scaffolds. The scaffolds are used as a substrate for the radial migration of cells.


telomeric loop formation

description: The process in which linear telomeric DNA is remodeled into duplex loops, by the invasion of a 3' single-stranded overhang into the duplex region.


name: high-affinity oligopeptide transmembrane transporter activity

description: Enables the transfer of oligopeptide from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.


name: negative regulation of iridophore differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of iridophore differentiation.


sulfonate dioxygenase activity

description: Catalysis of the reaction: sulfonate + 2-oxoglutarate + O2 = sulfite + aminoacetaldehyde + succinate + CO2.


name: positive regulation of negative chemotaxis

description: Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.


mesonephric collecting duct development

description: The process whose specific outcome is the progression of a collecting duct in the mesonephros over time, from its formation to the mature structure. The collecting duct regulates water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder.


description: Catalysis of the reaction: N-carbamoyl-L-2-amino acid + H2O = L-2-amino acid + NH3 + CO2. The N-carbamoyl-L-2-amino acid is a 2-ureido carboxylate.


name: fibroblast growth factor receptor signaling pathway involved in hemopoiesis

description: The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which contributes to hemopoiesis.


name: negative regulation of macrophage migration inhibitory factor signaling pathway

description: Any process that stops, prevents or reduces the frequency, rate or extent of macrophage migration inhibitory factor signaling pathway.


phage shock

description: A response by bacterial cells to a variety of stresses including filamentous phage infection, mislocalization of envelope proteins, extremes of temperature, osmolarity or ethanol concentration, and the presence of proton ionophores such as carbonylcyanide m-chlorophenylhydrazone (CCCP), that involves expression of the phage shock protein operon, and acts to protect the bacterial cells from damage.


name: positive regulation of platelet aggregation

description: Any process that activates or increases the frequency, rate or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.


name: deoxyribonucleoside 5'-monophosphate N-glycosidase activity

description: Catalysis of the reaction: a deoxyribonucleoside 5'-monophosphate + H2O = deoxyribose 5-monophosphate + a purine or pyrimidine base.


name: imaginal disc-derived male genitalia development

description: The process whose specific outcome is the progression of the male genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster.


conidiophore development

description: The process whose specific outcome is the progression of the conidiophore over time, from its formation to the mature structure. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.


1-naphthaldehyde dehydrogenase activity

description: Catalysis of the reaction: 1-naphthaldehyde + NAD+ + H2O = 1-naphthoic acid + NADH + H+.


name: cellular response to copper ion starvation

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of copper ions.


name: positive regulation of glutamatergic neuron differentiation

description: Any process that activates or increases the frequency, rate or extent of glutamatergic neuron differentiation.


response to inactivity

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inactivity stimulus.


dorsal aorta morphogenesis

description: The process in which the anatomical structures of the dorsal aorta are generated and organized. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once.


ITP diphosphatase activity

description: Catalysis of the reaction: ITP + H2O = IMP + H+ + diphosphate.


name: (deoxy)nucleoside phosphate kinase activity, dGTP as phosphate donor

description: Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-phosphate + dGTP = a 2'-deoxyribonucleoside 5'-diphosphate + dGDP.


name: semaphorin-plexin signaling pathway involved in axon guidance

description: Any semaphorin-plexin signaling pathway that is involved in axon guidance.


name: arachidonic acid 8,9-epoxygenase activity

description: Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to cis-8,9-epoxyeicosatrienoic acid.


glucuronoxylan metabolic process

description: The chemical reactions and pathways involving xylan, a polymer containing a beta-(1->4)-linked D-xylose backbone decorated with glucuronic acid side units.


myoblast proliferation

description: The multiplication or reproduction of myoblasts, resulting in the expansion of a myoblast cell population. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.


2-aminoadipate transaminase activity

description: Catalysis of the reaction: 2-oxoglutarate + L-2-aminoadipate = 2-oxoadipate + L-glutamate.


name: negative regulation of lipid transport across blood-brain barrier

description: Any process that stops, prevents or reduces the frequency, rate or extent of lipid transport across blood-brain barrier.


name: metanephric comma-shaped body morphogenesis

description: The process in which the metanephric comma-shaped body is generated and organized. The metanephric comma-shaped body is the precursor structure to the metanephric S-shaped body that contributes to the morphogenesis of a nephron in the metanephros.


name: regulation of chromosome attachment to the nuclear envelope

description: Any process that modulates the frequency, rate, extent or location of chromosome attachment to the nuclear envelope.


succinyl-CoA binding

description: Binding to succinyl-CoA, an omega-carboxyacyl-CoA having succinoyl as the S-acyl component.


name: negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis

description: Any process that decreases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.


formamide metabolic process

description: The chemical reactions and pathways involving formamide, the simplest amide, HCONH2, derived from formic acid.


pulmonary blood vessel remodeling

description: The reorganization or renovation of existing pulmonary blood vessels.


regulation of DNA stability

description: Any process that modulates the stability of DNA.


description: Catalysis of the reaction: NAD+ + 3-alpha-hydroxy-5-beta-androstane-17-one = NADH + H+ + 5-beta-androstane-3,17-dione.


name: negative regulation of B cell apoptotic process

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell apoptotic process.


description: Catalysis of the reaction: 2-oxoglutarate + H+ + isochorismate = 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate + CO2.


name: protein-glutathione oxidoreductase (glutathione) activity

description: Catalysis of the reaction: glutathionylated protein (PSSG) + glutathione (GSH) = protein-thiol (PSH) + glutathione disulfide (GSSG). The reaction may proceed via a 'monothiol' or 'dithiol' mechanism.


styrene monooxygenase activity

description: Catalysis of the reaction: styrene + NADPH + FADH + O2 = NADP+ + FAD+ + H2O + styrene oxide.


thermotaxis

description: The directed movement of a motile cell or organism in response to a temperature gradient. Movement may be towards either a higher or lower temperature.


cytochrome P450 4A1-heme linkage

description: The covalent linkage of heme to cytochrome P450 4A1 via hydroxyheme-L-glutamyl ester.


amylopectin binding

description: Binding to amylopectin.


licheninase activity

description: Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic linkages in beta-D-glucans containing (1->3) and (1->4) bonds.


description: Catalysis of the reaction: 1-hydroxypyrene + XSO3- = 1-pyrenylsulfate + HX.


description: Catalysis of the reaction: indole-3-acetate + L-methionine + ATP(4-) = H+ + indole-3-acetyl-methionine + AMP(2-) + diphosphoric acid.


modification of synaptic structure

description: Any process that modifies the structure/morphology of a synapse.


name: anterior lateral line neuromast hair cell morphogenesis

description: The change in form (cell shape and size) that occurs when an anterior lateral line neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface.


name: succinate dehydrogenase (quinone) activity

description: Catalysis of the reaction: a quinone + succinate = a quinol + fumarate.


neural plate elongation

description: The process in which the neural plate is shaped by the intrinsic movement of the epidermal and neural plate regions.


name: positive regulation of hemicellulose catabolic process

description: Any process that activates or increases the frequency, rate or extent of hemicellulose catabolic process.


name: regulation of synaptic transmission, GABAergic

description: Any process that modulates the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).


name: negative regulation of hepatic stellate cell proliferation

description: Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell proliferation.


3-cyanoalanine hydratase activity

description: Catalysis of the reaction: L-asparagine = 3-cyano-L-alanine + H2O + H+.


cystine reductase activity

description: Catalysis of the reaction: 2 L-cysteine + NAD+ = L-cystine + H+ + NADH.


negative regulation of JNK cascade

description: Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the JNK cascade.


name: negative regulation of C-C chemokine receptor CCR7 signaling pathway

description: Any process that stops, prevents or reduces the frequency, rate or extent of C-C chemokine receptor CCR7 signaling pathway.


iron chaperone activity

description: Directly binding to and delivering iron ions to a target protein.


response to isolation stress

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lack of contact with other members of the same species.


jasmonic acid metabolic process

description: The chemical reactions and pathways involving jasmonic acid, a fatty acid derivative with the formula (1R-(1 alpha, 2 beta(Z)))-3-oxo-2-(2-pentenyl)cyclopentaneacetic acid.


lamellipodium morphogenesis

description: A process that is carried out at the cellular level and in which the structure of a lamellipodium is organized.


response to peptide

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus.


4-hydroxyproline epimerase activity

description: Catalysis of the reaction: trans-4-hydroxy-L-proline = cis-4-hydroxy-D-proline.


description: Catalysis of the reaction: 3,5-dibromo-4-hydroxybenzoate + H+ = CO2 + 2,6-dibromophenol.


regulation of membrane repolarization

description: Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential, usually from positive to negative.


description: Catalysis of the reaction: glycerol + diphosphate = glycerol 1-phosphate + H+ + phosphate.


Notch signaling pathway

description: The series of molecular signals initiated by an extracellular ligand binding to the receptor Notch on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


response to astaxanthin

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an astaxanthin stimulus.


melatonin metabolic process

description: The chemical reactions and pathways involving melatonin (N-acetyl-5-methoxytryptamine).


outer dynein arm assembly

description: The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein outer arm, an outer arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes.


detection of dietary excess

description: The neurological process in which the brain senses excessive caloric intake.


name: cellular response to lipid hydroperoxide

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid hydroperoxide stimulus. Lipid hydroperoxide is the highly reactive primary oxygenated products of polyunsaturated fatty acids.


name: 3-monobromobisphenol A reductive dehalogenase activity

description: Catalysis of the reaction: 3-monobromobisphenol A + 2 H+ + 2 e- = bisphenol A + HBr.


transmembrane-ephrin receptor activity

description: Combining with a transmembrane ephrin to initiate a change in cell activity.


name: RNA splicing, via transesterification reactions with guanosine as nucleophile

description: Splicing of RNA via a series of two transesterification reactions with exogenous guanosine as the initiating nucleophile.


name: D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity

description: Catalysis of the reaction: D-arabinitol + NADP+ = D-ribulose + NADPH + H+.


skeletal muscle thin filament assembly

description: The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in skeletal muscle.


chenodeoxycholic acid binding

description: Binding to chenodeoxycholic acid.


name: positive regulation of blood vessel remodeling

description: Any process that activates or increases the frequency, rate or extent of blood vessel remodeling.


NADP-malic enzyme C4 photosynthesis

description: The process of C4 photosynthesis, as it occurs in plants in which the enzyme decarboxylating C4 acids in the bundle sheath is NADP-malic enzyme.


ribonucleoside metabolic process

description: The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.


immunoglobulin production

description: The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


name: pelargonidin 3-O-glucoside biosynthetic process

description: The chemical reactions and pathways resulting in the formation of pelargonidin 3-O-glucoside, a basic anthocyanin responsible for red to magenta coloration of flowers and fruits.


name: regulation of response to red or far red light

description: Any process that modulates the frequency, rate or extent of response to red or far red light.


name: p-hydroxyphenyl lignin metabolic process

description: The chemical reactions and pathways involving p-hydroxyphenyl lignin.


foraging behavior by probing substrate

description: Foraging behavior in which an anatomical part of the organism is inserted into the substrate to locate food.


oocyte maturation

description: A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization.


name: negative regulation of anterior head development

description: Any process that stops, prevents or reduces the frequency, rate or extent of anterior head development.


CDP biosynthetic process

description: The chemical reactions and pathways resulting in the formation of CDP, cytidine (5'-)diphosphate.


name: wobble position guanine ribose methylation

description: The process in which the ribose of guanosine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position.


name: peptidyl-proline hydroxylation to 3-hydroxy-L-proline

description: The modification of peptidyl-proline to form 3-hydroxy-L-proline; catalyzed by procollagen-proline 3-dioxygenase.


(1->4)-alpha-glucan metabolic process

description: The chemical reactions and pathways involving (1->4)-alpha-glucans, compounds composed of glucose residues linked by (1->4)-alpha-D-glucosidic bonds.


name: nucleotide-excision repair, DNA duplex unwinding

description: The unwinding, or local denaturation, of the DNA duplex to create a bubble around the site of the DNA damage.


name: modulation of G protein-coupled receptor activity in another organism

description: The process in which an organism effects a change in the activity of a G protein-coupled receptor in a second organism.


name: regulation of Cdc42 protein signal transduction

description: Any process that modulates the frequency, rate or extent of Cdc42 protein signal transduction.


detection of osmotic stimulus

description: The series of events in which a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell is received and converted into a molecular signal.


description: The chemical reactions and pathways resulting in the breakdown of 3-(2,3-dihydroxyphenyl)propanoate.


neuroblast fate determination

description: The cell fate determination process in which a cell becomes capable of differentiating autonomously into a neuroblast cell regardless of its environment; upon determination, the cell fate cannot be reversed. An example of this process is found in Mus musculus.


fetal process involved in parturition

description: A reproductive process occurring in the embryo that results in birth.


name: negative regulation of single-species biofilm formation on inanimate substrate

description: Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation on inanimate substrate.


cytochrome-c3 hydrogenase activity

description: Catalysis of the reaction: 2 H2 + ferricytochrome c3 = 4 H+ + ferrocytochrome c3.


name: galactose:sodium symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose(out) + Na+(out) = glucose(in) + Na+(in).


organelle organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.


phagosome reneutralization

description: Any process that increases the pH of the phagosome, measured by the concentration of the hydrogen ion, as part of the process of phagosome maturation.


name: viral release via disruption of host outer membrane

description: The dissemination of mature viral particles from a host cell via the destabilization of the cell outer membrane.


peptidyl-cysteine S-acetylation

description: The acetylation of peptidyl-cysteine to form peptidyl-S-acetyl-L-cysteine.


description: Catalysis of the reaction: NAD+ + [dinitrogen reductase] = nicotinamide + ADP-D-ribosyl-[dinitrogen reductase].


DNA ADP-ribosylation

description: The covalent attachment of an ADP-ribosyl group to a residue in double-stranded DNA.


umbilical cord morphogenesis

description: The process in which the anatomical structures of the umbilical cord are generated and organized. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta.


mitochondrial protein quality control

description: The chemical reactions and pathways resulting in the breakdown of misfolded proteins in the mitochondrion, which are targeted for degradation.


name: symbiont-mediated evasion of recognition by host pattern recognition receptor

description: A process by which a symbiont avoids recognition by host's innate immune response by altering or concealing a conserved molecule recognized by the host's cell surface and intracellular pattern recognition receptors, including Toll-like and NOD-like receptors. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: specification of ureteric bud anterior/posterior symmetry

description: The establishment of the ureteric bud such that there is a similar arrangement in form and relationship of parts along its anterior/posterior axis.


name: negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

description: Any process that decreases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand.


name: avascular cornea development in camera-type eye

description: The progression of an avascular cornea over time, from its formation to the mature structure. Corneal avascularity (the absence of blood vessels in the cornea) is required for optical clarity and optimal vision. Avascular corneas are present in most animals, except Manatees.


name: slug development involved in sorocarp development

description: The process whose specific outcome is the progression of the slug over time, from its formation to the mature structure. Slug development begins when the aggregate rises upwards to form a finger-shaped structure and ends when culmination begins. Slug development begins after aggregation and ends before culmination in sorocarp development.


name: positive regulation of mitotic cytokinesis, division site positioning

description: Any process that activates or increases the frequency, rate or extent of mitotic cytokinesis, division site positioning.


glycerol ether metabolic process

description: The chemical reactions and pathways involving glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol.


N-acylhexosamine oxidase activity

description: Catalysis of the reaction: N-acetyl-D-glucosamine + H2O + O2 = N-acetyl-D-glucosaminate + H2O2 + H+.


name: positive regulation of heart contraction

description: Any process that activates or increases the frequency, rate or extent of heart contraction.


noradrenergic neuron development

description: The process whose specific outcome is the progression of a noradrenergic neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.


name: asymmetric neuroblast division resulting in ganglion mother cell formation

description: Any process resulting in the physical partitioning and separation of a neuroblast into a neuroblast and a ganglion mother cell.


regulation of carbohydrate utilization

description: Any process that modulates the frequency, rate or extent of carbohydrate utilization.


name: symbiont-mediated disruption of host chloroplast thylakoid

description: The process in which an organism effects a change that impairs the structure or function of the host cell chloroplast thylakoid. The host is defined as the larger of the organisms involved in a symbiotic interaction.


description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: zinc(out) + HCO3-(out) + HO3Se-(out) = zinc(in) + HCO3-(in) + HO3Se-(out).


regulation of myelination

description: Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons.


sodium ion homeostasis

description: Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell.


description: Catalysis of the reaction: N-methylethanolamine phosphate + S-adenosyl-L-methionine = N,N-dimethylethanolamine phosphate + S-adenosyl-L-homocysteine + H+.


engulfment of target by autophagosome

description: The membrane invagination process by which an autophagosomal membrane surrounds an object that will be degraded by macroautophagy.


name: cellular response to sodium dodecyl sulfate

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium dodecyl sulfate (SDS) stimulus.


blue light photoreceptor activity

description: The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 400-470nm. The response may involve a change in conformation.


name: regulation of systemic arterial blood pressure by local renal renin-angiotensin

description: The process in which angiotensinogen metabolites in the kidney modulate the force with which blood passes through the renal circulatory system. The process begins when renin cleaves angiotensinogen.


protein K6-linked ubiquitination

description: A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 6 of the ubiquitin monomers, is added to a protein. K6-linked ubiquitination is involved in DNA repair.


meiotic prophase I

description: The cell cycle phase which is the first stage of meiosis I and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.


phosphoarginine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of phosphoarginine, a phosphorylated derivative of the amino acid arginine.


name: regulation of postsynaptic neurotransmitter receptor activity

description: Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity involved in synaptic transmission. Modulation may be via an effect on ligand affinity, or effector function such as ion selectivity or pore opening/closing in ionotropic receptors.


response to acetaldehyde

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetaldehyde stimulus.


autophagosome assembly

description: The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm.


name: positive regulation of antigen processing and presentation of peptide antigen via MHC class I

description: Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I.


name: negative regulation of diorcinol biosynthetic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of diorcinol biosynthetic process.


name: saturated monocarboxylic acid metabolic process

description: The chemical reactions and pathways involving saturated monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-) and fully saturated C-C bonds.


orcinol 2-monooxygenase activity

description: Catalysis of the reaction: H+ + NADH + O2 + orcinol = 2,3,5-trihydroxytoluene + H2O + NAD+.


description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: alpha-ketoglutarate(out) + H+(out) = alpha-ketoglutarate(in) + H+(in).


name: 1-alpha,25-dihydroxyvitamin D3 23-hydroxylase activity

description: Catatlysis of the reaction: calcitriol + 2 H+ + O2 + 2 reduced [adrenodoxin] = 1alpha,23S,25-trihydroxycholecalciferol + H2O + 2 oxidized [adrenodoxin].


foramen ovale closure

description: The morphogenetic process in which the foramen ovale closes after birth, to prevent blood flow between the right and left atria. In the fetal heart, the foramen ovale allows blood to enter the left atrium from the right atrium. Closure of the foramen ovale after birth stops this blood flow.


terpene synthase activity

description: Catalysis of the formation of cyclic terpenes through the cyclization of linear terpenes (e.g. isopentenyl-PP, geranyl-PP, farnesyl-PP and geranylgeranyl-PP) containing varying numbers of isoprene units.


name: positive regulation of mitotic cytokinesis

description: Any process that activates or increases the frequency, rate or extent of mitotic cytokinesis.


UDP-glucosamine 4-epimerase activity

description: Catalysis of the reaction: UDP-glucosamine = UDP-galactosamine.


renal phosphate excretion

description: The elimination of phosphate ions from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine.


name: protein C-linked glycosylation via tryptophan

description: The glycosylation of a carbon atom of a peptidyl-tryptophan residue.


description: The chemical reactions and pathways involving S-adenosylhomocysteine; the L-enantiomer is formed from S-adenosylmethionine and is a strong inhibitor of S-adenosylmethionine-mediated methylation reactions. It can be cleaved to form adenosine and homocysteine.


interleukin-19 production

description: The appearance of interleukin-19 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


name: metanephric interstitial fibroblast differentiation

description: The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblasts of the metanephros as it progresses from its formation to the mature state.


name: ripoptosome assembly involved in necroptotic process

description: The aggregation, arrangement and bonding together of ripoptosome components leading to a necroptotic process.


description: Catalysis of the reaction: UDP-alpha-D-xylose + zeatin = O-beta-D-xylosylzeatin + H+ + UDP.


hydroxymethylbilane synthase activity

description: Catalysis of the reaction: H2O + 4 porphobilinogen = hydroxymethylbilane + 4 NH4.


description: Catalysis of the reaction: S-adenosylmethionine + 7-(aminomethyl)-7-deazaguanosine-tRNA = adenine + methionine + epoxyqueuosine-tRNA. 7-(aminomethyl)-7-deazaguanosine-tRNA is also known as preQ1-tRNA, and epoxyqueuosine-tRNA as oQ-tRNA.


beta-alanyl amine synthase activity

description: Catalysis of the synthesis of beta-alanyl amine conjugate from a precursor biogenic amine, such as dopamine or histamine.


name: regulation of cellulose catabolic process

description: Any process that modulates the frequency, rate or extent of cellulose catabolic process.


regulation of granuloma formation

description: Any process that modulates the frequency, rate, or extent of granuloma formation.


name: peptidyl-tyrosine dehydrogenation to form (Z)-2,3-didehydrotyrosine

description: The oxidation of the C alpha-C beta bond of peptidyl-tyrosine to form peptidyl-(Z)-2,3-didehydrotyrosine coupled with cyclization of neighboring residues.


ribose isomerase activity

description: Catalysis of the reaction: ribofuranose = D-ribulose.


imaginal disc eversion

description: The eversion (turning inside out) of imaginal discs from their peripodial sacs, resulting in movement of the epithelium to the outside of the larval epidermis.


name: regulation of alpha-glucan metabolic process

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving alpha-glucans.


MCM complex binding

description: Binding to an MCM complex.


amidine-lyase activity

description: Catalysis of the release of amides or amidines by the cleavage of a carbon-nitrogen bond or the reverse reaction with an amide or amidine as a substrate.


mononuclear cell proliferation

description: The expansion of a mononuclear cell population by cell division. A mononuclear cell is a leukocyte with a single non-segmented nucleus in the mature form.


name: axial mesodermal cell fate determination

description: The process in which a cell becomes capable of differentiating autonomously into an axial mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.


name: uridine-rich cytoplasmic polyadenylylation element binding

description: Binding to a U-rich sequence in the 3'-end of nuclear-transcribed mRNAs; required for cytoplasmic polyadenylylation.


hepatic duct development

description: The progression of the hepatic duct over time, from its formation to the mature structure. The hepatic duct is the duct that leads from the liver to the common bile duct.


1,4-dichlorobenzene catabolic process

description: The chemical reactions and pathways resulting in the breakdown of 1,4-dichlorobenzene (p-dichlorobenzene or paramoth), a derivative of benzene with two chlorine atoms attached at opposite positions on the ring.


name: protein localization to lateral cortical node

description: A process in which a protein is transported to, or maintained in, a location within a lateral cortical node.


name: oxidoreductase activity, acting on a heme group of donors

description: Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.


description: Catalysis of the reaction: bis(4-chlorophenyl)acetate + H+ = CO2 + bis(4-chlorophenyl)methane. Bis(4-chlorophenyl)acetate is also known as DDA; bis(4-chlorophenyl)methane is also known as DDM.


response to doxorubicin

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a doxorubicin stimulus.


mitochondrial DNA metabolic process

description: The chemical reactions and pathways involving mitochondrial DNA.


protein uridylylation

description: The addition of phospho-uridine to a protein amino acid.


description: The chemical reactions and pathways resulting in the formation of trimethylenediamine.


ADP catabolic process

description: The chemical reactions and pathways resulting in the breakdown of ADP, adenosine 5'-diphosphate.


name: aspartate family amino acid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine.


name: RNA-protein covalent cross-linking via peptidyl-serine

description: The formation of a covalent cross-link between RNA and a peptidyl-serine residue by the formation of O-(phospho-5'-5NA)-L-serine.


name: protein insertion into membrane from inner side

description: The process in which a protein is incorporated into a lipid bilayer, e.g., the prokaryotic, mitochondrial, or chloroplast inner membrane, from the inner side.


cellular response to glucose starvation

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of glucose.


name: adenylate cyclase-inhibiting dopamine receptor signaling pathway

description: An adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway initiated by dopamine binding to its receptor, and ending with the regulation of a downstream cellular process.


name: response to low light intensity stimulus

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low light intensity stimulus. Low light intensity is defined as a level of electromagnetic radiation at or below 0.1 micromols/m2.


sno(s)RNA 3'-end cleavage

description: The endonucleolytic cleavage of snoRNA 3' ends, which is required for mature snoRNAs to be functional.


description: Catalysis of the reaction: cis-1,2-dihydronaphthalene-1,2-diol + NAD+ = naphthalene-1,2-diol + NADH + H+.


name: positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response

description: Any process that activates or increases the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response.


name: negative regulation of plant-type hypersensitive response

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the hypersensitive response in a plant.


name: maintenance of protein location in mitochondrion

description: Any process in which a protein is maintained in a specific location in a mitochondrion, and is prevented from moving elsewhere.


inner dynein arm assembly

description: The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein inner arm, an inner arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes.


name: positive regulation of the force of heart contraction by neuronal norepinephrine

description: The process in which the release of norepinephrine from nerve endings modulates the force of heart muscle contraction.


leaf phyllotactic patterning

description: The radial pattern formation process that results in the formation of leaf primordia around the center of a shoot apical meristem.


name: regulation of purine nucleoside transport

description: Any process that modulates the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


name: phenol-containing compound catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring.


cardiac muscle cell differentiation

description: The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.


dense core granule maturation

description: Steps required to transform a dense core granule generated at the trans-Golgi network into a fully formed and transmissible dense core granule. Dense core granule maturation proceeds through clathrin-mediated membrane remodeling events and is essential for efficient processing of cargo within dense core granules as well as for removing factors that might otherwise interfere with dense core granule trafficking and exocytosis.


name: mesonephric cell migration involved in male gonad development

description: The orderly movement of a cell from the mesonephros to the male gonad, contributing to its development.


name: branched-chain amino acid:sodium symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: branched-chain amino acid(out) + cation(out) = branched-chain amino acid(in) + cation(in).


nipple morphogenesis

description: The process in which the nipple is generated and organized.


name: L-cysteine catabolic process via cystine

description: The chemical reactions and pathways resulting in the breakdown of L-cysteine, via the intermediate cystine.


ethanol biosynthetic process

description: The chemical reactions and pathways resulting in the formation of ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation.


axon choice point recognition

description: The recognition of molecules at a choice point by an axon growth cone; at a choice point the growth cone determines the direction of its future growth.


serotonin receptor activity

description: Combining with the biogenic amine serotonin and transmitting a signal across a membrane by activating some effector activity. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates.


phenylacetaldehyde reductase activity

description: Catalysis of the reaction: 2-phenylethanol + NADP = phenylacetaldehyde + NADPH + H+.


description: Catalysis of the reaction: 2,4-dihydroxy-hept-trans-2-ene-1,7-dioate = pyruvate + succinic semialdehyde.


name: symbiont-mediated suppression of host translation termination

description: A process in which a symbiont inhibits or disrupts translation termination of host mRNAs. The host is defined as the larger of the organisms involved in a symbiotic interaction.


detection of unfolded protein

description: The series of events in which an unfolded protein stimulus is received and converted into a molecular signal.


cordyol C catabolic process

description: The chemical reactions and pathways resulting in the breakdown of cordyol C.


histone H4K20 demethylase activity

description: Catalysis of the removal of the methyl group from a modified lysine residue at position 20 of the histone H4 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.


nephron epithelium development

description: The process whose specific outcome is the progression of the nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The nephron epithelium is a tissue that covers the surface of a nephron.


name: positive regulation of pattern recognition receptor signaling pathway

description: Any process that decreases the rate, frequency or extent of a pattern recognition receptor signaling pathway.


response to muscle inactivity

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle inactivity stimulus.


name: icosanoid transmembrane transporter activity

description: Enables the transfer of icosanoids from one side of a membrane to the other.


urethanase activity

description: Catalysis of the reaction: H2O + H+ + urethane = CO2 + ethanol + NH4.


motor learning

description: Any process in which an organism acquires a novel neuromuscular action or movement as the result of experience.


ubiquinone-6 biosynthetic process

description: The chemical reactions and pathways resulting in the formation of ubiquinone-6.


cell volume homeostasis

description: Any process involved in maintaining the steady state of a cell's volume. The cell's volume refers to the three-dimensional space occupied by a cell.


name: response to G2 DNA damage checkpoint signaling

description: A process that occurs in response to signals generated as a result of G2/M transition DNA damage checkpoint signaling.


description: Catalysis of the reaction: curcumin 4'-O-beta-D-gentiotrioside + UDP-alpha-D-glucose = curcumin 4'-O-beta-D-gentiotetraside + UDP + H+.


name: regulation of endothelial cell chemotaxis to vascular endothelial growth factor

description: Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis to vascular endothelial growth factor.


name: negative regulation of mitotic cell cycle phase transition

description: Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle phase transition.


name: murein tripeptide carboxypeptidase activity

description: Catalysis of the reaction L-Ala-gamma-D-Glu-meso-Dap (murein tripeptide) + H2O = L-Ala-gamma-D-Glu + meso-diaminopimelate.


adenine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of adenine, 6-aminopurine, one of the five main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.


lens fiber cell development

description: The process whose specific outcome is the progression of a lens fiber cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a lens fiber cell fate. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.


name: negative regulation of myeloid dendritic cell activation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid dendritic cell activation.


neural crest cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a neural crest cell.


type IIa hypersensitivity

description: An inflammatory response resulting in cell death mediated by activation of the classical complement pathway or induction of effector cell phagocytosis or cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell.


detection of humidity

description: The series of events in which a humidity stimulus is received and converted into a molecular signal.


cellular response to caffeine

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them.


name: 2,5-dioxovalerate dehydrogenase (NAD+) activity

description: Catalysis of the reaction: 2,5-dioxopentanoate + NAD+ + H2O = 2-oxoglutarate + NADH + H+.


apocarotenoid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of apocarotenoids, a class of compounds derived from the oxidative cleavage of carotenoids, many of which are biologically important e.g. retinal and abscisic acid.


pyrimidine nucleoside metabolic process

description: The chemical reactions and pathways involving any pyrimidine nucleoside, one of a family of organic molecules consisting of a pyrimidine base covalently bonded to ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).


name: extracellular regulation of signal transduction

description: Any regulation of signal transduction that takes place in the extracellular region.


name: regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide

description: Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to hydrogen peroxide.


name: regulation of neuroinflammatory response

description: Any process that modulates the frequency, rate or extent of neuroinflammatory response.


protein decrotonylase activity

description: Catalysis of the reaction: H2O + N6-(2E)-butenoyl-L-lysyl-[protein] = (2E)-2-butenoate + L-lysyl-[protein].


ectoine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid), a tetrahydropyrimidine commonly synthesized by halophilic bacteria.


6-oxohexanoate dehydrogenase activity

description: Catalysis of the reaction: 6-oxohexanoate + NADP+ + H2O = adipate + NADPH + H+.


name: positive regulation of intestinal absorption

description: Any process that activates or increases the frequency, rate or extent of intestinal absorption.


regulation of membrane depolarization

description: Any process that modulates the rate, frequency or extent of membrane depolarization. Membrane depolarization is the process in which membrane potential changes in the depolarizing direction from the resting potential, usually from negative to positive.


name: positive regulation of mesenchymal cell apoptotic process

description: Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process.


CENP-A containing chromatin assembly

description: The formation of chromatin containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres, and the central core in modular centromeres.


name: regulation of respiratory burst involved in inflammatory response

description: Any process that modulates the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.


phyllome development

description: The process whose specific outcome is the progression of a phyllome over time, from its formation to the mature structure. A phyllome is a collective term for all the different types of leaves appearing on plants.


name: cis-2,3-dihydrodiol DDT dehydrogenase activity

description: Catalysis of the reaction: cis-2,3-dihydrodiol DDT + NADP+ = NADPH + 2,3-dihydroxy DDT.


name: fibroblast growth factor receptor signaling pathway involved in heart development

description: The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands and contributing to the progression of the heart over time.


lysosomal lumen acidification

description: Any process that reduces the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion.


lactoylglutathione lyase activity

description: Catalysis of the reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal.


name: positive regulation of lymphangiogenesis

description: Any process that activates or increases the frequency, rate or extent of lymphangiogenesis.


kidney smooth muscle tissue development

description: The process whose specific outcome is the progression of smooth muscle in the kidney over time, from its formation to the mature structure.


endothelial tip cell fate specification

description: The process involved in the specification of identity of an endothelial tip cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. An endothelial tip cell is a specialized endothelial cell localized to the leading edge of an angiogenic sprout that senses extracellular signals and guides the directed growth of blood vessels.


thiamine metabolic process

description: The chemical reactions and pathways involving thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.


name: clustering of voltage-gated sodium channels

description: The process in which voltage-gated sodium channels become localized together in high densities. In animals, nodes of Ranvier differ dramatically from internodal axonal regions in very high densities of voltage-dependent sodium (Nav) channels responsible for the rapid, inward ionic currents that produce membrane depolarization.


name: metanephric proximal tubule morphogenesis

description: The process in which the anatomical structures of a metanephric proximal tubule are generated and organized. The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology.


name: positive regulation of entry into reproductive diapause

description: Any process that activates or increases the rate or extent of the dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.


name: positive regulation of vesicle transport along microtubule

description: Any process that activates or increases the frequency, rate or extent of vesicle transport along microtubule.


name: mitochondrion-endoplasmic reticulum membrane tethering

description: The attachment of a mitochondrion and an endoplasmic reticulum via molecular tethers that physically bridge their respective membranes and attach them to each other. The tethering may facilitate exchange of metabolites between the organelles.


proboscis extension reflex

description: The extension, through direct muscle actions, of the proboscis (the trunk-like extension of the mouthparts on the adult external head) in response to a nutritional stimulus.


name: positive regulation of plant-type cell wall cellulose catabolic process

description: Any process that activates or increases the frequency, rate or extent of plant-type cell wall cellulose catabolic process.


name: inferior olivary nucleus structural organization

description: The process that contributes to the act of creating the structural organization of the inferior olivary nucleus structure. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.


description: Catalysis of the reaction: lithocholate + NAD+ = 3-oxo-5beta-cholanate + H+ + NADH.


primary amine oxidase activity

description: Catalysis of the reaction: a primary amine + H2O + O2 = an aldehyde + NH3 + hydrogen peroxide.


oligodendrocyte apoptotic process

description: Any apoptotic process in an oligodendrocyte. Oligodendrocytes belong to a class of large neuroglial (macroglial) cells in the central nervous system, where they form the insulating myelin sheath of axons.


name: negative regulation of early stripe melanocyte differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of early stripe melanocyte differentiation.


fatty-acyl-CoA biosynthetic process

description: The chemical reactions and pathways resulting in the formation of a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group.


cellulase activity

description: Catalysis of the endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.


granzyme A production

description: The appearance of granzyme A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


description: Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamate + D-lysinium(1+) + ATP = UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-D-lysine + ADP + hydrogenphosphate + H+.


response to catechin

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catechin stimulus.


cellular response to hydroxyisoflavone

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyisoflavone stimulus.


prostaglandin metabolic process

description: The chemical reactions and pathways involving prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities.


collagen metabolic process

description: The chemical reactions and pathways involving collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).


name: negative regulation of synaptic vesicle recycling

description: Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle recycling.


3-oxo-myristate decarboxylase activity

description: Catalysis of the reaction: 3-oxo-myristate + H+ = 2-tridecanone + carbon dioxide.


name: peptidyl-lactic acid biosynthetic process from peptidyl-serine

description: The modification of N-terminal peptidyl-serine to lactic acid.


name: response to molecule of oomycetes origin

description: Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of oomycetes origin.


riboflavin phosphotransferase activity

description: Catalysis of the reaction: alpha-D-glucose 1-phosphate + riboflavin = D-glucose + FMN.