description: Catalysis of the random hydrolysis of (1->4)-beta-D-mannosidic linkages in mannans, galactomannans, glucomannans, and galactoglucomannans.


name: negative regulation of substrate-dependent cell migration, cell attachment to substrate

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Any process that stops, prevents or reduces the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate.


type II pneumocyte differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a type II pneumocyte. A type II pneumocyte is a surfactant secreting cell that contains abundant cytoplasm containing numerous lipid-rich multilamellar bodies.


name: methyl tert-butyl ether metabolic process

description: The chemical reactions and pathways involving methyl tert-butyl ether, 2-methoxy-2-methylpropane. Methyl tert-butyl ether is a synthetic chemical which is mixed with gasoline for use in reformulated gasoline. It was first introduced as an additive for unleaded gasoline in the 1980s. It is also used as a laboratory reagent and a pharmaceutical agent.


name: protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + fructose(out) = protein histidine + fructose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.


metanephric short nephron development

description: The process whose specific outcome is the progression of a short nephron in the metanephros over time, from its formation to the mature structure. Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb.


name: positive regulation of B-1 B cell differentiation

description: Any process that activates or increases the frequency, rate or extent of B-1 B cell differentiation.


name: pituitary adenylate cyclase-activating polypeptide receptor activity

description: A G protein-coupled receptor that interacts with pituitary adenylate cyclase-activating polypeptide.


name: toxin transmembrane transporter activity

description: Enables the transfer of a toxin from one side of a membrane to the other. A toxin is a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.


name: negative regulation of chlorophyll biosynthetic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of chlorophyll biosynthetic process.


catecholamine metabolic process

description: The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.


name: cellular process involved in reproduction in multicellular organism

description: A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism.


diphosphotransferase activity

description: Catalysis of the transfer of a diphosphate group from one compound (donor) to a another (acceptor).


phenylacetyl-CoA dehydrogenase activity

description: Catalysis of the reaction: 2 1,4-benzoquinone + H2O + phenylacetyl-CoA = 2 hydroquinone + phenylglyoxylyl-CoA.


name: negative regulation of cardiac muscle tissue regeneration

description: Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle tissue regeneration.


name: positive regulation of interleukin-17-mediated signaling pathway

description: Any process that activates or increases the frequency, rate or extent of interleukin-17-mediated signaling pathway.


8-oxocoformycin reductase activity

description: Catalysis of the reaction: coformycin + NADP+ = 8-oxocoformycin + 2 H+ + NADPH.


description: Catalysis of the reaction: 1-O-alkyl-2-acetyl-sn-glycerol + acyl-CoA = 1-O-alkyl-2-acetyl-3-acyl-sn-glycerol + CoA.


name: retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission

description: Modulation of synaptic transmission by cell-cell signaling across the synaptic cleft from postsynapse to presynapse, mediated by a neuropeptide.


cellular response to hydrogen sulfide

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen sulfide stimulus.


intronic box H/ACA snoRNA processing

description: Any process involved in the conversion of a primary box H/ACA type small nucleolar RNA (snoRNA) transcript that resides within, and is processed from, the intron of a pre-mRNA into a mature box H/ACA snoRNA.


name: negative regulation of establishment or maintenance of cell polarity regulating cell shape

description: Any process that stops, prevents or reduces the frequency, rate or extent of establishment or maintenance of cell polarity regulating cell shape.


name: regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

description: Any process that modulates the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway.


name: regulation of striated muscle contraction

description: Any process that modulates the frequency, rate or extent of striated muscle contraction.


description: Catalysis of the reaction: tetrahydroxypteridine = H+ + xanthine-8-carboxylate.


external genitalia morphogenesis

description: The process in which the anatomical structures of the external genitalia are generated and organized. The external genitalia are the outer sex organs, such as the penis or vulva in mammals.


name: positive regulation of gamma-delta T cell differentiation

description: Any process that activates or increases the frequency, rate or extent of gamma-delta T cell differentiation.


response to growth factor

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.


cellular response to decane

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a decane stimulus.


maintenance of seed dormancy

description: Any process that maintains a seed in a dormant state.


histone crotonyltransferase activity

description: Catalysis of the reaction: crotonyl-CoA + histone = CoA + crotonyl-histone.


description: Catalysis of the reaction: (S)-reticulinium(1+) + S-adenosyl-L-methionine = H+ + laudanine(1+) + S-adenosyl-L-homocysteine.


fluorene oxygenase activity

description: Catalysis of the reaction: fluorene + 2 H+ + 2 e- + O2 = H2O + 9-fluorenol.


name: positive regulation of complement-dependent cytotoxicity

description: Any process that activates or increases the frequency, rate or extent of complement-dependent cytotoxicity.


chlorophyll synthetase activity

description: Catalysis of the reaction: chlorophyllide a + 2 H+ + phytyl diphosphate = chlorophyll a + diphosphate.


name: L-idonate transmembrane transporter activity

description: Enables the transfer of L-idonate from one side of a membrane to the other. L-idonate is an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose.


endothelial microparticle formation

description: The cellular component organization process in which microparticles bud off from an endothelial cell.


cellular response to alcohol

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus.


name: envenomation resulting in plasminogen activation in another organism

description: The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with the activation of plasminogen into plasmin in the bitten organism. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide.


name: thiamine-containing compound catabolic process

description: The chemical reactions and pathways resulting in the breakdown of thiamine (vitamin B1), and compounds derived from it.


IkappaB kinase complex binding

description: Binding to a IkappaB kinase complex.


name: purine ribonucleotide transmembrane transporter activity

description: Enables the transfer of a purine ribonucleotide, any compound consisting of a purine ribonucleoside (a purine organic base attached to a ribose sugar) esterified with (ortho)phosphate, from one side of a membrane to the other.


lamellipodium organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lamellipodium. A lamellipodium is a thin sheetlike process extended by the leading edge of a crawling fibroblast; contains a dense meshwork of actin filaments.


name: ABC-type fatty-acyl-CoA transporter activity

description: Catalysis of the reaction ATP + H2O + fatty acyl CoA(Side 1) = ADP + phosphate + fatty acyl CoA(Side 2). A fatty acyl CoA group is any acyl group derived from a fatty acid with a coenzyme A group attached to it.


amelogenesis

description: The process whose specific outcome is the formation of tooth enamel, occurring in two stages: secretory stage and maturation stage.


crotonyl-CoA reductase activity

description: Catalysis of the reduction of crotonyl-CoA to butyryl-CoA.


name: negative regulation of lateral mesodermal cell fate determination

description: Any process that stops, prevents, or reduces the frequency, rate or extent of lateral mesoderm cell fate determination.


endocardial cushion development

description: The progression of a cardiac cushion over time, from its initial formation to the mature structure. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.


regulation of cell differentiation

description: Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features.


peptidyl-tryptophan hydroxylation

description: The hydroxylation of peptidyl-tryptophan, to form peptidyl-L-3-hydroxytryptophan.


description: Catalysis of the reaction: ATP + L-glutamate + L-propargylglycine = ADP + H+ + L-gamma-glutamyl-L-propargylglycine + phosphate.


dendrite self-avoidance

description: The process in which dendrites recognize and avoid contact with sister dendrites from the same cell.


dimethylarsinate reductase activity

description: Catalysis of the reaction: dimethylarsinate + 3 H+ + 2 e- = dimethylarsinous acid + H2O.


name: voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels

description: Positive regulation of presynaptic cytosolic calcium ion concentrations via the directed movement of calcium ions across the plasma-membrane into the cytosol via the action of voltage-gated calcium ion channels. This is the first step in synaptic transmission.


cellular response to erythromycin

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythromycin stimulus.


description: Catalysis of the reaction: (1E,2Z)-3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate + H2O = 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oate + (2Z,4Z)-2-hydroxyhexa-2,4-dienoate + H+.


diplotene

description: The cell cycle phase which follows pachytene during prophase I of meiosis, during which the homologous chromosomes begin to separate and the synaptonemal complex dissolves.


nitrogen fixation

description: The process in which nitrogen is taken from its relatively inert molecular form (N2) in the atmosphere and converted into nitrogen compounds useful for other chemical processes, such as ammonia, nitrate and nitrogen dioxide.


description: Catalysis of the reaction: N-acetyl-LL-2,6-diaminopimelate + H2O = LL-2,6-diaminopimelate + acetate.


name: protein lipidation involved in autophagosome assembly

description: The protein lipidation process by which phosphatidylethanolamine is conjugated to a protein of the ATG8 family, leading to membrane insertion of the protein as a step in autophagosome assembly.


delta-carotene catabolic process

description: The chemical reactions and pathways resulting in the breakdown of delta-carotene.


name: regulation of non-canonical NF-kappaB signal transduction

description: Any process that modulates the frequency, rate or extent of the non-canonical NF-kappaB signaling cascade.


name: regulation of mini excitatory postsynaptic potential

description: Any process that modulates the frequency, rate or extent of mini excitatory postsynaptic potential. Mini excitatory postsynaptic potential is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse.


name: tRNA-specific adenosine deaminase activity

description: Catalysis of the reaction: adenosine + H2O = inosine + NH3, in a tRNA molecule.


septin ring assembly

description: The aggregation, arrangement and bonding together of septins and associated proteins to form an organized structure resembling a ring at the cell cortex.


name: sequestering of nodal from receptor via nodal binding

description: Binding to a nodal protein in the extracellular region, and inhibiting nodal signaling by preventing nodal from binding to its cell surface receptor.


regulation of ERBB signaling pathway

description: Any process that modulates the frequency, rate or extent of ERBB signaling pathway.


SAGA complex assembly

description: The aggregation, arrangement and bonding together of a set of components to form a SAGA complex, a SAGA-type histone acetyltransferase complex that contains Spt8 (in budding yeast) or a homolog thereof.


description: Catalysis of the reaction: UDP-alpha-D-glucose + 4-hydroxylamino-2,6-dinitrotoluene = 4-hydroxylamino-2,6-dinitrotoluene-O-glucoside + UDP + H+.


plant organ formation

description: The process that gives rise to the plant organ. This process pertains to the initial formation of a structure from unspecified parts.


description: Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methylguanosine.


name: negative regulation of raffinose biosynthetic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of raffinose biosynthetic process.


glycolipid mannosyltransferase activity

description: Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-D-mannosyl-D-mannose linkage.


oculomotor nerve formation

description: The process that gives rise to the oculomotor nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.


positive regulation of cell volume

description: Any process that increases cell volume.


microtubule stabilizing activity

description: A protein-containing complex stabilizing activity that prevents dissociation of microtubules.


glucan metabolic process

description: The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues.


peptidyl-threonine modification

description: The modification of peptidyl-threonine.


maintenance of location

description: Any process in which a cell, substance or cellular entity, such as a protein complex or organelle, is maintained in a location and prevented from moving elsewhere.


seed dormancy process

description: A dormancy process in which dormancy (sometimes called a dormant state) is induced, maintained or broken in a seed. Seed dormancy is a suspension of most physiological activity and growth in a seed, including the embryo contained therein, that can be reactivated. It often requires special conditions for reactivation, such as specific temperature, scarification, or leaching of inhibitors.


dorsal/ventral axis specification

description: The establishment, maintenance and elaboration of the dorsal/ventral axis. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.


sperm capacitation

description: A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium.


name: positive regulation of small GTPase mediated signal transduction

description: Any process that activates or increases the frequency, rate or extent of small GTPase mediated signal transduction.


anterior cibarial plate morphogenesis

description: The process in which the anatomical structures of the anterior cibarial plate are generated and organized.


name: DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, resulting in the induction of the transcription of p21 (also known as WAF1, CIP1 and SDI1) or any equivalent protein, in response to the detection of DNA damage.


name: calcium,diacylglycerol-dependent serine/threonine kinase activity

description: Calcium-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.


inulin catabolic process

description: The chemical reactions and pathways resulting in the breakdown of inulin.


name: afferent axon development in anterior lateral line nerve

description: The process whose specific outcome is the progression of an afferent axon in the anterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in the anterior lateral line nerve.


name: protease localization to mast cell secretory granule

description: Any process in which a protease is transported to, or maintained in, a location within a secretory granule in a mast cell.


fructose catabolic process

description: The chemical reactions and pathways resulting in the breakdown of fructose, the ketohexose arabino-2-hexulose.


name: regulation of initiation of premeiotic DNA replication

description: Any process that modulates the frequency, rate or extent of initiation of premeiotic DNA replication.


flavonoid sulfotransferase activity

description: Catalysis of the reaction: a flavonoid + 3'-phosphoadenosine-5'-phosphosulfate = sulfated flavonoid + adenosine-3',5'-diphosphate. This reaction is the transfer of a sulfate group to the hydroxyl group of a flavonoid acceptor, producing the sulfated flavonoid derivative.


name: positive regulation of cellobiose catabolic process

description: Any process that activates or increases the frequency, rate or extent of cellobiose catabolic process.


peptidyl-lysine carboxyethylation

description: The modification of peptidyl-lysine to form peptidyl-N6-1-carboxyethyl-L-lysine.


arugosin metabolic process

description: The chemical reactions and pathways involving arugosin.


name: negative regulation of response to amylopectin

description: Any process that stops, prevents or reduces the frequency, rate or extent of response to amylopectin.


T cell tolerance induction

description: A process involving any mechanism for tolerance induction in T cells.


name: leukocyte adhesion to arterial endothelial cell

description: The attachment of a leukocyte to an arterial endothelial cell via adhesion molecules.


L-leucine metabolic process

description: The chemical reactions and pathways involving L-leucine, 2-amino-4-methylpentanoic acid.


methyl-CpNpG binding

description: Binding to a methylated cytosine/unspecified/guanine trinucleotide.


description: Catalysis of the reaction: kaempferide + S-adenosyl-L-methionine = 7,4'-dimethylkaempferol + S-adenosyl-L-homocysteine.


name: negative regulation of toll-like receptor 4 signaling pathway

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 4 signaling pathway.


name: positive regulation of endothelial cell chemotaxis to fibroblast growth factor

description: Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis to fibroblast growth factor.


retinal binding

description: Binding to retinal, one of the forms of vitamin A. Retinal plays an important role in the visual process in most vertebrates, combining with opsins to form visual pigments in the retina.


description: Catalysis of the reaction: pyridoxamine + pyruvate = L-alanine + pyridoxal.


description: Catalysis of the reaction: ATP + pantetheine 4'-phosphate = 3'-dephospho-CoA + diphosphate.


description: Catalysis of the reaction: 2 a peptidoglycan dimer (tetrapeptide) + 3 H2O = a peptidoglycan tetramer with L,D cross-links (L-Lys-D-Asn-L-Lys) + di-trans,poly-cis-undecaprenyl diphosphate + 4 D-alanine.


apoptosome assembly

description: The aggregation, arrangement and bonding together of the apoptosome, a multisubunit protein complex involved in the signaling phase of the apoptotic process.


thymine dehydrogenase activity

description: Catalysis of the reaction: H2O + thymine + acceptor = 5-methyl-barbiturate + donor-H2.


clathrin coat disassembly

description: The disaggregation of a clathrin coat into its constituent components; results in stripping or removing the clathrin coat from clathrin-coated vesicles (CCV) before fusing with their targets. CVVs transport cargo from plasma membrane and trans-Golgi to the endosomal system.


abequosyltransferase activity

description: Catalysis of the reaction: CDP-abequose + D-mannosyl-L-rhamnosyl-D-galactose-1-diphospholipid = CDP + D-abequosyl-D-mannosyl-rhamnosyl-D-galactose-1-diphospholipid.


name: anaerobic phenol-containing compound catabolic process

description: The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen.


olfactory behavior

description: The behavior of an organism in response to an odor.


cartilage condensation

description: The condensation of mesenchymal cells that have been committed to differentiate into chondrocytes.


response to acetate

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus.


name: regulation of organelle transport along microtubule

description: Any process that modulates the frequency, rate or extent of organelle transport along microtubule.


name: epithelial cell migration involved in metanephric nephron tubule morphogenesis

description: The orderly movement of epithelial cells within a renal tubule that contributes to metanephric nephron tubule morphogenesis.


disproportionation of elemental sulfur

description: The process in which sulfur compounds with an intermediate oxidation state serve as both electron donors and electron acceptors in an energy-generating redox process. The reaction takes place anaerobically, in light and in the absence of CO2.


name: negative regulation of lung alveolus development

description: Any process that stops, prevents or reduces the frequency, rate or extent of lung alveolus development.


histone H3R2 methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 2) = S-adenosyl-L-homocysteine + (histone H3)-N-methyl-arginine (position 2). This reaction is the addition of a methyl group to the arginine residue at position 2 of histone H3.


lipoxygenase pathway

description: The chemical reactions and pathways by which an unsaturated fatty acid (such as arachidonic acid or linolenic acid) is converted to other compounds, and in which the first step is hydroperoxide formation catalyzed by lipoxygenase.


macrolide metabolic process

description: The chemical reactions and pathways involving macrolides, any of a large group of polyketide compounds that contain a large lactone ring with few or no double bonds and no nitrogen atoms, linked glycosidically to one or more sugar groups. The macrolides include the carbomycins, the erythromycins, oleandomycin, oligomycins, and the spiramycins, and act as antibiotics, mainly against Gram-positive bacteria.


seminal vesicle epithelium development

description: The progression of the seminal vesicle epithelium over time, from its formation to the mature structure.


name: somatic diversification of immunoglobulins

description: The somatic process that results in the generation of sequence diversity of immunoglobulins.


description: Catalysis of the reaction: all-trans-nonaprenyl diphosphate + H+ + homogentisate = 2-methyl-6-all-trans-nonaprenylbenzene-1,4-diol + CO2 + diphosphate. 2-methyl-6-solanyl-1,4-benzoquinonone is also known as 2-methyl-6-solanesylplastoquinol and all-trans-nonaprenyl diphosphate as solanesyl diphosphate.


PRC1 complex binding

description: Binding to a PRC1 complex.


purine nucleobase salvage

description: Any process that generates purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from derivatives of them without de novo synthesis.


regulation of adenosine transport

description: Any process that modulates the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


name: aerobic respiration, using nitrite as electron donor

description: The oxidation of nitrite (NO2) to nitrate (NO3), using oxygen (O2) as the electron acceptor. Nitrite oxidation is the final step in nitrification, the oxidation of ammonia to nitrate, and nitrite oxidoreductase (NOR) is the key enzyme complex that catalyzes the conversion of nitrite to nitrate in nitrite oxidizing species.


description: Catalysis of the reaction: (R)-1,2,3,4-tetrahydronaphthol = 1,2,3,4-tetrahydronaphthalone + 2 H+ + 2 e-.


COPII vesicle uncoating

description: The process in which COPII vesicle coat proteins are disassembled, and released.


name: glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity

description: Catalysis of the reaction: L-glutamine + glutamyl-tRNA(Gln) + ATP = L-glutamate + glutaminyl-tRNA(Gln) + phosphate + ADP.


renal cortex development

description: The process whose specific outcome is the progression of the renal cortex over time, from its formation to the mature structure. The renal cortex is the outer region of the kidney.


cellular response to antibiotic

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.


alpha-amylase activity

description: Catalysis of the endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more alpha-(1->4)-linked D-glucose units.


apical dendrite morphogenesis

description: The process in which the anatomical structures of an apical dendrite are generated and organized.


description: Catalysis of the reaction: S-adenosyl-L-methionine + a [release factor]-L-glutamine = S-adenosyl-L-homocysteine + H+ + a [release factor]-N5-methyl-L-glutamine.


1-phenylethanol dehydrogenase activity

description: Catalysis of the reaction: (S)-1-phenylethanol + NAD+ = acetophenone + H+ + NADH.


name: sulfite transmembrane transporter activity

description: Enables the transfer of sulfite ions from one side of a membrane to the other.


discadenine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid.


description: Catalysis of the reaction: (2R)-3-amino-2-methylpropanoate + pyruvate = 2-methyl-3-oxopropanoate + L-alanine.


name: NAD(P)+ transhydrogenase (Si-specific) activity

description: Catalysis of the reaction: NADPH + NAD+ = NADP+ + NADH.


response to brassinosteroid

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brassinosteroid stimulus.


name: regulation protein catabolic process at presynapse

description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the presynapse.


bacteriochlorophyll binding

description: Binding to bacteriochlorophyll, a form of chlorophyll found in photosynthetic bacteria, such as the purple and green bacteria. There are several types, designated a to g. Bacteriochlorophyll a and bacteriochlorophyll b are structurally similar to the chlorophyll a and chlorophyll b found in plants.


name: pouch outgrowth involved in semicircular canal formation

description: The morphogenetic process in which an epithelial sheet bends along a linear axis and gives rise to a pouch that will form a semicircular canal.


ensheathment of neuronal cell bodies

description: The process in which satellite glial cells isolate neuronal cell bodies.


name: negative regulation of transporter activity

description: Any process that stops or reduces the activity of a transporter.


name: establishment of body hair planar orientation

description: Orientation of body hairs, projections from the surface of an organism, such that the hairs all point in a uniform direction along the surface.


interleukin-33 receptor activity

description: Combining with interleukin-33 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


L-lysine 6-oxidase activity

description: Catalysis of the reaction: L-lysine + H2O + O2 = allysine + H2O2 + NH4.


name: GDP-mannose biosynthetic process from mannose

description: The chemical reactions and pathways resulting in the formation of GDP-mannose from mannose.


regulation of mRNA metabolic process

description: Any process that modulates the frequency, rate or extent of mRNA metabolic process.


cellular response to interleukin-17

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-17 stimulus.


leucoanthocyanidin reductase activity

description: Catalysis of the reaction: (2R,3S)-catechin + NADP+ + H2O = 2,3-trans-3,4-cis-leucocyanidin + NADPH + H+.


name: double-strand break repair via single-strand annealing, removal of nonhomologous ends

description: During DSBR via single-strand annealing, the removal of nonhomologous sequences at the broken 3' single-strand DNA end before DNA repair synthesis can occur.


sno(s)RNA catabolic process

description: The chemical reactions and pathways resulting in the breakdown of snoRNA, small nucleolar RNA, any of a class of small RNAs that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins.


name: killing by virus of host cell by post-segregational killing

description: The process by which a virus causes the death of daughter cells which do not contain its genes after host cell division, by a mechanism of post-segregational killing (PSK). The extrachromosomal viral DNA consist of two genes; the product of the second is long lived and toxic, while the product of the first is short lived and antagonizes the lethal action of the toxin. Daughter cells that do not contain the viral extrachromosomal element are killed by the long lived toxin, while daughter cells that do contain the viral extrachromosomal element are protected by the action of the short lived antitoxin it encodes.


description: The chemical reactions and pathways resulting in the formation of the exopolysaccharide galactosaminogalactan. GAG is a heteropolysaccharide composed of alpha-1,4 linked galactose, N-acetyl galactosamine (GalNAc) and galactosamine (GalN).


name: regulation of L-glutamine import across plasma membrane

description: Any process that modulates the frequency, rate or extent of L-glutamine import into cell.


response to wounding

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.


choline-sulfatase activity

description: Catalysis of the reaction: choline sulfate + H2O = choline + H+ + sulfate.


regulation of membrane potential

description: Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.


UDP-rhamnose metabolic process

description: The chemical reactions and pathways involving UDP-L-rhamnose, a substance composed of rhamnose in glycosidic linkage with uridine diphosphate.


name: regulation of Schwann cell differentiation

description: Any process that modulates the frequency, rate or extent of Schwann cell differentiation.


name: 6-phosphoglucan, water dikinase activity

description: Catalysis of the reaction: n ATP + n H2O + a 6-phosphogluco-maltodextrin = n AMP + n hydrogenphosphate + a poly-6-phosphogluco-maltodextrin.


name: TRAIL death-inducing signaling complex assembly

description: The aggregation, arrangement and bonding together of a set of components to form a TRAIL death-inducing signaling complex.


sn-glycerol 3-phosphate binding

description: Binding to sn-glycerol 3-phosphate.


fatty acid homeostasis

description: Any process involved in the maintenance of an internal steady state of fatty acid within an organism or cell.


name: symbiont-mediated evasion of host innate immune response

description: A process by which a symbiont avoids recognition by host's innate immune response by altering, concealing or destroying a conserved symbiont molecule recognized by the host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


response to Aroclor 1254

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an Aroclor 1254 stimulus.


regulation of ascus development

description: Any process that modulates the frequency, rate or extent of ascus development, a process that leads to the formation of basidium, a sac-like structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed.


name: positive regulation of border follicle cell migration

description: Any process that activates or increases the frequency, rate or extent of border follicle cell migration.


name: negative regulation of steroid metabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving steroids.


name: negative regulation of horizontal cell localization

description: Any process that stops, prevents or reduces the frequency, rate or extent of horizontal cell localization.


name: positive regulation of aortic smooth muscle cell differentiation

description: Any process that activates or increases the frequency, rate or extent of aortic smooth muscle cell differentiation.


myeloid dendritic cell chemotaxis

description: The movement of a myeloid dendritic cell in response to an external stimulus.


flagellated sperm motility

description: The directed, self-propelled movement of a cilium (aka flagellum) that contributes to the movement of a flagellated sperm.


lupeol 28-monooxygenase activity

description: Catalysis of the reaction: lupeol + NADPH(4-) + O2 + H+ = betulin + NADP(3-) + H2O.


name: shikimate 3-dehydrogenase (NADP+) activity

description: Catalysis of the reaction: shikimate + NADP+ = 3-dehydroshikimate + NADPH + H+.


spliceosomal snRNP assembly

description: The aggregation, arrangement and bonding together of one or more snRNA and multiple protein components to form a ribonucleoprotein complex that is involved in formation of the spliceosome.


10-oxogeraniol oxidoreductase activity

description: Catalysis of the reaction: (6E)-8-oxogeraniol + NADP = (6E)-8-oxogeranial + NADPH + H+.


structural constituent of egg chorion

description: The action of a molecule that contributes to the structural integrity of an egg chorion. An example of this is found in Drosophila melanogaster.


description: Catalysis of the reaction: zeaxanthin + 2 NADH + 2 H+ + 2 O2 = nostoxanthin + 2 NAD + 2 H2O.


name: negative regulation of hormone metabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any hormone.


name: lymph gland plasmatocyte differentiation

description: The process in which a relatively unspecialized larval lymph gland-derived hemocyte precursor cell acquires the specialized features of the phagocytic blood-cell type, the plasmatocyte.


name: negative regulation of mesodermal cell fate specification

description: Any process that stops, prevents, or reduces the frequency, rate or extent of mesoderm cell fate specification.


name: regulation of ER to Golgi vesicle-mediated transport

description: Any process that modulates the rate, frequency, or extent of ER to Golgi vesicle-mediated transport, the directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.


dirigent protein activity

description: Catalysis of the reaction: 2 H+ + 2 coniferol + O2 = (+)-pinoresinol + 2 H2O.


violaxanthin de-epoxidase activity

description: Catalysis of the reaction: violaxanthin + 2 ascorbate = zeaxanthin + 2 dehydroascorbate + 2 H2O; and antheraxanthin + ascorbate = zeaxanthin + dehydroascorbate + H2O.


pigment accumulation

description: The aggregation of coloring matter in a particular location in an organism, tissue or cell, occurring in response to some external stimulus.


cell-cell junction organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-cell junction. A cell-cell junction is a specialized region of connection between two cells.


low-affinity IgE receptor activity

description: Combining with low affinity with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


name: negative regulation of cell differentiation involved in phenotypic switching

description: Any process that stops, prevents or reduces the frequency, rate or extent of cell differentiation involved in phenotypic switching.


protein retention in Golgi apparatus

description: The retention of proteins within the Golgi apparatus. Golgi-localized carbohydrate-modifying enzymes have a short N-terminal domain that faces the cytosol, a single transmembrane alpha helix, and a large C-terminal domain that faces the Golgi lumen and that contains the catalytic site. How the membrane-spanning alpha helix in a Golgi enzyme causes its localization and prevents its movement to the plasma membrane is not known.


fourth ventricle development

description: The process whose specific outcome is the progression of the fourth ventricle over time, from its formation to the mature structure. The fourth ventricle is an irregularly shaped cavity in the rhombencephalon, between the medulla oblongata, the pons, and the isthmus in front, and the cerebellum behind. It is continuous with the central canal of the cord below and with the cerebral aqueduct above, and through its lateral and median apertures it communicates with the subarachnoid space.


L-ascorbate oxidase activity

description: Catalysis of the reaction: 4 L-ascorbate + O2 = 4 monodehydroascorbate + 2 H2O.


RNA strand-exchange activity

description: Facilitates the displacement of one strand of an RNA-RNA duplex and its replacement with a different strand of higher complementarity.


name: choline biosynthetic process via CDP-choline

description: The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate CDP-choline.


superior raphe nucleus development

description: The process whose specific outcome is the progression of the superior raphe nucleus over time, from its formation to the mature structure.


creatinine catabolic process to formate

description: The chemical reactions and pathways resulting in the breakdown of creatinine into other compounds, including formate.


name: 4-hydroxybenzoate amino acid synthetase activity

description: Catalysis of the reaction: 4-hydroxybenzoate + ATP + amino acid = 4-hydroxybenzoyl amino acid conjugate + AMP + diphosphate.


name: S-(hydroxymethyl)glutathione dehydrogenase (NADP+) activity

description: Catalysis of the reaction: S-(hydroxymethyl)glutathione + NADP+ = S-formylglutathione + NADPH + H+.


name: positive regulation of Schwann cell migration

description: Any process that activates or increases the frequency, rate or extent of Schwann cell migration.


ventral midline development

description: The process whose specific outcome is the progression of the ventral midline over time, from its formation to the mature structure. In protostomes (such as insects, snails and worms) as well as deuterostomes (vertebrates), the midline is an embryonic region that functions in patterning of the adjacent nervous tissue. The ventral midline in insects is a cell population extending along the ventral surface of the embryo and is the region from which cells detach to form the ventrally located nerve cords. In vertebrates, the midline is originally located dorsally. During development, it folds inwards and becomes the ventral part of the dorsally located neural tube and is then called the ventral midline, or floor plate.


name: negative regulation of synoviocyte proliferation

description: Any process that stops, prevents or reduces the frequency, rate or extent of synoviocyte proliferation.


5S rRNA binding

description: Binding to a 5S ribosomal RNA, the smallest RNA constituent of a ribosome.


name: ventricular compact myocardium morphogenesis

description: The process in which the anatomical structures of the compact cardiac ventricle muscle are generated and organized.


name: regulation of developmental pigmentation

description: Any process that modulates the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.


name: response to diacyl bacterial lipopeptide

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diacylated bacterial lipopeptide stimulus.


name: flavin-containing compound metabolic process

description: The chemical reactions and pathways involving a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position.


name: high-affinity zinc transmembrane transporter activity

description: Enables the transfer of zinc ions (Zn2+) from one side of a membrane to the other, probably powered by proton motive force. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.


name: shikimate transmembrane transporter activity

description: Enables the transfer of shikimate from one side of a membrane to the other. Shikimate is an important intermediate in the biosynthesis of aromatic amino acids.


name: mesonephric glomerular parietal epithelial cell fate commitment

description: The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular parietal epithelial cell. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes.


fruit ripening

description: An developmental maturation process that has as participant a fruit. Ripening causes changes in one or more characteristics of a fruit (color, aroma, flavor, texture, hardness, cell wall structure) and may make it more attractive to animals and aid in seed dispersal.


response to photoperiod, blue light

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a blue light photoperiod stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm.


halogen metabolic process

description: The chemical reactions and pathways involving any halogen, elements of Group VII; includes metabolism of halogen-containing compounds.


description: Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-galactosamine.


corrin metabolic process

description: The chemical reactions and pathways involving corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule.


peptidyl-threonine octanoylation

description: The octanoylation of peptidyl-threonine to form peptidyl-O3-octanoyl-L-threonine, typical of the protein ghrelin.


Fc-gamma receptor signaling pathway

description: The series of molecular signals initiated by the binding of the Fc portion of immunoglobulin G (IgG) to an Fc-gamma receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region.


renal capsule specification

description: The regionalization process in which the identity of the renal capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.


hyponitrite reductase activity

description: Catalysis of the reaction: 2 hydroxylamine + 2 NAD+ = 2 H+ + hyponitrous acid + 2 NADH.


ciliary body morphogenesis

description: The process in which the ciliary body generated and organized. The ciliary body is the circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes.


description: Catalysis of the random hydrolysis of (1->6) linkages in (1->6)-beta-D-glucans.


name: neural crest-derived cardiac glial cell differentiation

description: The process in which a neural crest cell acquires the specialized features of a glial cell of the heart.


nucleobase metabolic process

description: The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent of a nucleic acid, e.g. the purines: adenine, guanine, hypoxanthine, xanthine and the pyrimidines: cytosine, uracil, thymine.


name: mitochondrial protein-transporting ATPase activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the mitochondrion via the mitochondrial inner membrane translocase complex.


name: molybdenum incorporation into metallo-sulfur cluster

description: The incorporation of molybdenum into a metallo-sulfur cluster.


cellular response to glutathione

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glutathione stimulus.


alpha-glucosidase activity

description: Catalysis of the hydrolysis of terminal, non-reducing alpha-linked alpha-D-glucose residue with release of alpha-D-glucose.


name: formation of peptidyl-cystine persulfide by sulphur transfer from H2S

description: The modification of a peptidyl-cystine residue in a protein by the direct addition of H2S, followed by the removal of 2 protons to form peptidyl-cysteine persulfide.


folate reductase activity

description: Catalysis of the reaction: 7,8-dihydrofolate + NADP+ = folate + NADPH + H+.


glyoxal metabolic process

description: The chemical reactions and pathways involving glyoxal.


name: 1-deoxy-D-xylulose 5-phosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of 1-deoxy-D-xylulose 5-phosphate, the 5-phospho derivative of 1-deoxy-D-xylulose. 1-deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway and a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis.


name: regulation of stomatal complex patterning

description: Any process that modulates the frequency, rate or extent of stomatal complex patterning.


response to mycophenolic acid

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycophenolic acid stimulus.


name: 3,5-dichloro-THPH methyl transferase activity

description: Catalysis of the reaction: (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one + S-adenosyl-L-methionine = 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one + H+ + S-adenosyl-L-homocysteine.


name: UDP-glucuronic acid dehydrogenase activity

description: Catalysis of the reaction: UDP-glucuronate + NAD+ = UDP-beta-L-threo-pentapyranos-4-ulose + CO2 + NADH + H+.


description: Catalysis of the reaction: selenocysteine + S-adenosyl-L-methionine = Se-methylselenocysteine + S-adenosyl-homocysteine.


oxalate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of oxalate, the organic acid ethanedioate.


4-hydroxytryptamine kinase activity

description: Catalysis of the reaction: 4-hydroxytryptamine + ATP = 4-hydoxytryptamine 4-phosphate + ADP + H+.


name: mammillotegmental axonal tract development

description: The process in which the mammillotegmental tract progresses over time, from its formation to the mature structure. The mammillotegmental tract is the collection of axons that connects the ventral diencephalon to the tegmentum and pons.


name: very-low-density lipoprotein particle clearance

description: The process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.


regulation of dopamine secretion

description: Any process that modulates the frequency, rate or extent of the regulated release of dopamine.


neural plate axis specification

description: The pattern specification process in which the axes of the nervous system are established.


name: NAD-dependent protein de-2-hydroxyisobutyrylase activity

description: Catalysis of the reaction: H2O + N6-(2-hydroxyisobutanoyl)-L-lysyl-[protein] + NAD+ = 2''-O-(2-hydroxyisobutanoyl)-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.


galactoxylomannan biosynthetic process

description: The chemical reactions and pathways resulting in the formation of the exopolysaccharide galactoxylomannan. Galactoxylomannan is produced by a pathogenic fungus and causes paralysis in some animals.


lysosomal membrane organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosomal membrane. A lysosomal membrane is the lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.


7S RNA binding

description: Binding to a 7S RNA, the RNA component of the signal recognition particle (SRP).


name: negative regulation of cellotriose metabolic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of cellotriose metabolic process.


phototropism

description: The movement of an organism, or part of an organism, in response to a light stimulus, usually toward or away from it.


malonyl-CoA biosynthetic process

description: The chemical reactions and pathways resulting in the formation of malonyl-CoA, the S-malonyl derivative of coenzyme A.


name: formation of peptidyl-cystine persulfide by sulphur transfer from free cysteine

description: The modification of a peptidyl-cystine residue in a protein by the transfer of a sulfur atom from a free cysteine (in the process converting the free cysteine to alanine) to the peptidyl-cysteine to form peptidyl-cysteine persulfide.


name: phenol-containing compound metabolic process

description: The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring.


leukocyte mediated immunity

description: Any process involved in the carrying out of an immune response by a leukocyte.


name: mesonephric nephron tubule morphogenesis

description: The process in which the anatomical structures of a mesonephric nephron tubule are generated and organized. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros.


name: secondary active transmembrane transporter activity

description: Enables the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy, not direct ATP coupling. Secondary active transporters include symporters and antiporters.


premeiotic DNA replication termination

description: Any DNA replication termination involved in meiotic cell cycle DNA replication.


peptidyl-pyrromethane cofactor linkage

description: The covalent binding of a pyrromethane (dipyrrin) cofactor to protein via the sulfur atom of cysteine forming dipyrrolylmethanemethyl-L-cysteine.


description: Catalysis of the reaction: P1-P6-bis(5'-adenosyl) hexaphosphate + H2O = AMP + adenosine 5'-pentaphosphate.


name: negative regulation of vasculature development

description: Any process that stops, prevents or reduces the frequency, rate or extent of vasculature development.


mitochondrial RNA surveillance

description: The set of processes involved in identifying and degrading defective or aberrant RNAs that takes place in the mitochondrion.


name: corticospinal neuron axon guidance through the cerebral peduncle

description: The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the internal capsule through the cerebral peduncle in response to a combination of attractive and repulsive cues.


establishment of organelle localization

description: The directed movement of an organelle to a specific location.


description: The methylation of 5-hydroxy-L-lysine to form peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine.


name: (R)-4-hydroxyphenyllactate dehydrogenase (NADP+) activity

description: Catalysis of the reaction: NADP+ + (R)-3-(4-hydroxyphenyl)lactate = NADPH + H+ + 3-(4-hydroxyphenyl)pyruvate.


name: regulation of cellodextrin catabolic process

description: Any process that modulates the frequency, rate or extent of cellodextrin catabolic process.


sevenless signaling pathway

description: The series of molecular signals initiated by an extracellular ligand binding to sevenless (sev; a receptor tyrosine kinase) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: negative regulation of nerve growth factor production

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of production of nerve growth factor (NGF).


eoxin E4 synthase activity

description: Catalysis of the reaction: eoxin D4 + H20 = eoxin E4 + glycine.


name: medulla reticulospinal tract morphogenesis

description: Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the medulla towards target cells in the spinal cord.


name: cellular response to lipoprotein particle stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus.


FAT10 conjugating enzyme activity

description: Isoenergetic transfer of FAT10 from one protein to another via the reaction X-FAT10 + Y = Y-FAT10 + X, where both the X-FAT10 and Y-FAT10 linkages are thioester bonds between the C-terminal amino acid of FAT10 and a sulfhydryl side group of a cysteine residue.


name: regulation of cell differentiation involved in embryonic placenta development

description: Any process that modulates the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state.


description: Catalysis of the reaction: nucleoside triphosphate + aminoglycoside = diphosphate + nucleotidylaminoglycoside.


name: positive regulation of CD8-positive, alpha-beta T cell proliferation

description: Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation.


homocysteine metabolic process

description: The chemical reactions and pathways involving homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid. Homocysteine is an important intermediate in the metabolic reactions of its S-methyl derivative, methionine.


snRNA methylation

description: The posttranscriptional addition of methyl groups to specific residues in an snRNA molecule.


embryonic hindlimb morphogenesis

description: The process, occurring in the embryo, by which the anatomical structures of the hindlimbs are generated and organized. The hindlimbs are the posterior limbs of an animal.


regulation of vesicle docking

description: Any process that modulates the frequency, rate or extent of vesicle docking.


antennal development

description: The process whose specific outcome is the progression of the antenna over time, from its formation to the mature structure. The antenna are the sensory structures on the head that are capable of detecting various environmental stimuli.


angioblast cell differentiation

description: The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an angioblast cell. Angioblasts are one of the two products formed from hemangioblast cells (the other being pluripotent hemopoietic stem cells).


peptidyl-lysine malonylation

description: The addition of a malonyl group (CO-CH2-CO) to peptidyl-lysine to form N6-malonyl-L-lysine.


regulation of B cell activation

description: Any process that modulates the frequency, rate or extent of B cell activation.


name: adult salivary gland boundary specification

description: Determination in an adult organism of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland.


name: propionate transmembrane transporter activity

description: Enables the transfer of propionate from one side of a membrane to the other. Propionate (or propanoate) is the organic acid CH3-CH2-COOH.


description: The dehydration of peptidyl-S-carbamoyl-L-cysteine to form peptidyl-S-cyano-L-cysteine.


description: Catalysis of the reaction: a branched-chain amino acid + 2-oxoglutarate = L-glutamate + a 2-oxocarboxylate derived from the branched-chain amino acid.


negative regulation of ovulation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary.


name: symbiont-mediated perturbation of host actin cytoskeleton via actin filament reorganization

description: The process in which an organism effects a change that impairs the structure or function of the host actin cytoskeleton by reorganizing the actin filaments, in a way that keeps the total filementous actin remains approximately constant. The host is defined as the larger of the organisms involved in a symbiotic interaction.


cell-matrix recognition

description: Cell recognition that involves the interaction of the cell with the extracellular matrix.


mammary gland duct regression in males

description: The process in which the epithelium of the mammary duct is destroyed in males.


N-methyl nucleosidase activity

description: Catalysis of the reaction: 7-methylxanthosine + H2O = 7-methylxanthine + H+ + ribofuranose.


name: cardiac epithelial to mesenchymal transition

description: A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.


phosphoserine-tRNA(Cys) ligase activity

description: Catalysis of the reaction: tRNA(Cys) + O-phospho-L-serine + ATP = AMP + diphosphate + phosphoseryl-tRNA(Cys).


name: protein localization to cytosolic proteasome complex

description: A process in which a protein is transported to, or maintained in, a location within a cytosolic proteasome complex.


nucleobase binding

description: Binding to a nucleobase, any of a class of pyrmidines or purines, organic nitrogenous bases.


name: protein localization to actin cortical patch

description: A process in which a protein is transported to, or maintained in, an actin cortical patch.


phlobaphene metabolic process

description: The chemical reactions and pathways involving phlobaphenes, red pigments with oligomeric or polymeric structure derived from the flavonoid intermediate flavan-4-ols.


name: positive regulation of heart rate by norepinephrine

description: The process in which the secretion of norepinephrine into the bloodstream or released from nerve endings increases the rate of heart muscle contraction.


basket cell precursor proliferation

description: The multiplication or reproduction of neuroblasts that will give rise to basket cells. A cerebellar basket cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.


mitotic cell cycle

description: Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.


regulation of G0 to G1 transition

description: A cell cycle process that modulates the rate or extent of the transition from the G0 quiescent state to the G1 phase.


gluconate dehydratase activity

description: Catalysis of the reaction: D-gluconate = 2-dehydro-3-deoxy-D-gluconate + H2O.


name: positive regulation of mast cell proliferation

description: Any process that activates or increases the rate or extent of mast cell proliferation.


7SK snRNA binding

description: Binding to a 7SK small nuclear RNA (7SK snRNA).


bisdemethoxycurcumin synthase activity

description: Catalysis of the reaction: 2 4-coumaryl-CoA + malonyl-CoA + H2O + H+ = 3 coenzyme A + bisdemethoxycurcumin + 2 carbon dioxide.


description: Catalysis of the reaction: S-adenosyl-L-methionine + myricetin = S-adenosyl-L-homocysteine + laricitrin.


ectopic germ cell programmed cell death

description: Programmed cell death of an errant germ line cell that is outside the normal migratory path or ectopic to the gonad. This is an important mechanism of regulating germ cell survival within the embryo.


description: Catalysis of the reaction: L-glutamate + ATP + NADPH = ADP + L-glutamate gamma-semialdehyde + NADP+ + phosphate.


response to blue light

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a blue light stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm.


name: glial cell migration in anterior lateral line nerve

description: The movement of a glial cell along the axons in the anterior lateral line nerve.


name: regulation of proline import across plasma membrane

description: Any process that modulates the frequency, rate or extent of proline import into cell.


bromide peroxidase activity

description: Catalysis of the reaction: 2 R-H + 2 bromide + H2O2 = 2 R-Br + 2 H2O. Enzymes with this activity often accept other halide ions as substrates, including chloride and iodide.


name: regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

description: Any process that modulates the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning.


schizogony

description: Cell division by multiple fission in which nuclei and other organelles in the parent cell divide repeatedly and move to the cell periphery before internal membranes develop around them, producing a large number of daughter cells simultaneously.


name: inhibitory C-type lectin receptor signaling pathway

description: The series of molecular signals initiated by an extracellular ligand binding to an inhibitory C-type lectin receptor capable of inhibiting an immune effector process contributing to an immune response.


vacuole-mitochondria membrane tethering

description: The attachment of a mitochondrial membrane to a vacuolar membrane via molecular tethers that physically bridge their respective membranes and attach them to each other. The tethering may facilitate exchange of metabolites between the organelles.


description: Catalysis of the reaction: coniferyl aldehyde + H2O + NAD(P)+ = ferulate + NAD(P)H + H+.


heme oxidation

description: The chemical reactions and pathways resulting in the loss of electrons from one or more atoms in heme.


name: negative regulation of muscle cell apoptotic process

description: Any process that decreases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.


description: Catalysis of the reaction: 1,2-dihydroxyphenanthrene + UDP-glucose = 2-hydroxy-1-phenanthryl-beta-D-glucopyranoside + UDP.


name: symbiont entry into host cell via disruption of host cell envelope

description: The disruption by a symbiont of host cell envelope components to allow entry into the host cell.


plasmid maintenance

description: The maintenance of the integrity of extrachromosomal plasmid DNA; includes processes that ensure plasmids are retained in the daughter cells after cell division.


R-loop processing

description: A DNA metabolic process that results in the disassembly of R-loops. R-loops are three-stranded nucleic acid structures consisitng of an RNA:DNA heteroduplex and a looped-out non-template strand. Aberrant formation and persistence of R-loops block transcription elongation and cause DNA damage. Mechanisms that resolve R-loops are essential for genome stability.


heart morphogenesis

description: The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.


name: deoxynucleotide transmembrane transporter activity

description: Catalyzes transport of all four deoxy (d) NDPs, and, less efficiently, the corresponding dNTPs, in exchange for dNDPs, ADP, or ATP.


name: cell growth mode switching, filamentous to budding

description: The process in which a cell switches from growing as a filament (elongated cells attached end-to-end) to growing as a round budding cell. An example of this is observed in Candida albicans.


name: negative regulation of glomerular mesangial cell proliferation

description: Any process that decreases the frequency, rate or extent of glomerular mesangial cell proliferation.


cerebellum vasculature morphogenesis

description: The process in which the vasculature of the cerebellum is generated and organized.


name: regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway

description: Any process that modulates the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway.


cellular response to diosgenin

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diosgenin stimulus.


dihydroorotase activity

description: Catalysis of the reaction: (S)-dihydroorotate + H2O = N-carbamoyl-L-aspartate + H+.


renal sodium excretion

description: The elimination of sodium ions from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine.


description: Catalysis of the reaction: 1,2,3-tri-(9Z,12Z)-octadecadienoylglycerol + N-(30-hydroxytriacontanoyl)-sphing-4-enine = di-(9Z,12Z)-octadecadienoylglycerol + N-[30-(9Z,12Z-octadecadienoyloxy)-triacontanoyl]-sphing-4-enine.


propan-2-ol metabolic process

description: The chemical reactions and pathways involving propan-2-ol.


dehiscence

description: The opening of an anther, fruit or other structure, which permits the escape of reproductive bodies contained within it.


isoflavonoid metabolic process

description: The chemical reactions and pathways involving isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids, containing a flavan skeleton. They are differentiated from flavonoids by the point of attachment of the aromatic ring group.


cGMP-mediated signaling

description: An intracellular signaling cassette that starts with production of cyclic GMP (cGMP), and ends with activation of downstream effectors that further transmit the signal within the cell.


CCL19-activated CCR7 signaling pathway

description: The series of molecular signals initiated by the binding of the C-C chemokine CCL19 to a C-C chemokine type 7 receptor (CCR7) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: cell motility involved in cerebral cortex radial glia guided migration

description: The movement of a cell along the process of a radial glial cell involved in cerebral cortex glial-mediated radial migration.


name: negative regulation of catecholamine metabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catecholamine.


anhydrosialidase activity

description: Catalysis of the reaction: an N-acetylneuraminate glycoside = 2,7-anhydro-alpha-N-acetylneuraminate + an alpha-sialyl group. This reaction is the elimination of alpha-sialyl groups in N-acetylneuraminic acid glycosides, releasing 2,7-anhydro-alpha-N-acetylneuraminate.


nucleic acid biosynthetic process

description: The biosynthetic process resulting in the formation of a nucleic acid.


CD27 signaling pathway

description: The series of molecular signals initiated by the binding of the cell surface receptor CD27 to its physiological ligand CD70, and ending with the regulation of a downstream cellular process, e.g. transcription.


glucocorticoid metabolic process

description: The chemical reactions and pathways involving glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.


name: Mo-molybdopterin cofactor catabolic process

description: The chemical reactions and pathways resulting in the breakdown of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.


phosphogluconate dehydratase activity

description: Catalysis of the reaction: 6-phospho-D-gluconate = 2-dehydro-3-deoxy-6-phospho-D-gluconate + H2O.


description: Catalysis of the reaction: UDP-alpha-D-glucose(2-) + medicagenate = UDP(3-) + a medicagenate monoglucoside.


quinoline 2-oxidoreductase activity

description: Catalysis of the reaction: quinoline + acceptor + H2O = isoquinolin-1(2H)-one + reduced acceptor.


name: negative regulation of lamellocyte differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.


name: negative regulation of fibroblast apoptotic process

description: Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast apoptotic process.


name: hypoxia-inducible factor-proline dioxygenase activity

description: Catalysis of the reaction: 2-oxoglutarate + L-prolyl-[hypoxia-inducible factor alpha subunit] + O2 = CO2 + succinate + trans-4-hydroxy-L-prolyl-[hypoxia-inducible factor alpha subunit].


description: Catalysis of the reaction: UDP-N-acetyl-alpha-D-quinovosamine + NAD(P) = UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose + H+ + NAD(P)H.


specification of axis polarity

description: The pattern specification process in which the polarity of a body or organ axis is established and maintained.


name: positive regulation of T cell extravasation

description: Any process that activates or increases the frequency, rate or extent of T cell extravasation.


name: negative regulation of cell differentiation involved in stem cell population maintenance

description: Any negative regulation of cell differentiation that is involved in stem cell population maintenance.


heterotrimeric G-protein binding

description: Binding to a heterotrimeric G-protein.


description: Catalysis of the reaction: phenylacetyl-CoA + L-glutamine = CoA + alpha-N-phenylacetyl-L-glutamine.


slime layer organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a slime layer. A slime layer is an easily removed, diffuse, unorganized layer of extracellular material that surrounds a cell.


protein-heme P460 linkage

description: The linkage of protein to heme P460.


background adaptation

description: Any process in which an organism changes its pigmentation (lightening in response to a brighter environment or darkening in response to a dimmer environment) in response to a change in light intensity.


name: regulation of neurotransmitter loading into synaptic vesicle

description: Any process that modulates the frequency, rate or extent of neurotransmitter loading into synaptic vesicles.


name: D-arabitol catabolic process to xylulose 5-phosphate

description: The chemical reactions and pathways resulting in the breakdown of D-arabitol to form xylulose 5-phosphate. D-arabitol is converted into D-xylulose, which is then phosphorylated to form D-xylulose-5-phosphate.


preribosome binding

description: Binding to a preribosome.


forebrain development

description: The process whose specific outcome is the progression of the forebrain over time, from its formation to the mature structure. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions).


RNA polymerase IV activity

description: Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase IV specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.


verruculogen biosynthetic process

description: The chemical reactions and pathways resulting in the formation of verruculogen.


anaerobic fructose catabolic process

description: The chemical reactions and pathways resulting in the breakdown of fructose that occurs in the absence of oxygen.


name: molybdenum cofactor cytidylyltransferase activity

description: Catalysis of the reaction CTP + molybdenum cofactor = diphosphate + cytidylyl molybdenum cofactor.


histidine N-acetyltransferase activity

description: Catalysis of the reaction: L-histidine + acetyl-CoA = N(alpha)-acetyl-L-histidine + CoA + H+.


retinal blood vessel morphogenesis

description: The process whose specific outcome is the progression of a blood vessel of the retina over time, from its formation to the mature structure.


name: positive regulation of nematode larval development

description: Any process that increases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.


eye-antennal disc morphogenesis

description: The process in which the anatomical structures derived from the eye-antennal disc are generated and organized. This includes the transformation of an eye-antennal imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the eye, antenna, head capsule and maxillary palps.


name: right ventricular compact myocardium morphogenesis

description: The process in which the anatomical structures of the right ventricular compact myocardium are generated and organized.


name: positive regulation of dopaminergic neuron differentiation

description: Any process that activates or increases the frequency, rate or extent of dopaminergic neuron differentiation.


name: negative regulation of L-dopa decarboxylase activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of L-dopa decarboxylase activity.


engulfment of apoptotic cell

description: The removal of the apoptotic cell by phagocytosis, by a neighboring cell or by a phagocyte.


regulation of foraging behavior

description: Any process that modulates the frequency, rate or extent of foraging behavior.


name: hormonal regulation of the force of heart contraction

description: The process in which the hormones modulates the force of heart muscle contraction. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action.


gentisate decarboxylase activity

description: Catalysis of the reaction: 2,5-dihydroxybenzoate + H+ = CO2 + hydroquinone.


response to interleukin-6

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus.


protein-hormone receptor activity

description: Combining with a protein hormone to initiate a change in cell activity.


box H/ACA sno(s)RNA 3'-end processing

description: Any process involved in forming the mature 3' end of a box H/ACA RNA molecule.


peptide cross-linking via L-cystine

description: The oxidation of two peptidyl-cysteine residues to form a peptidyl-L-cystine (dicysteine) in which segments of peptide chain are linked by a disulfide bond; the cross-link may be between different or the same peptide chain.


regulation of nitrogen utilization

description: Any process that modulates the frequency, rate or extent of nitrogen utilization.


myoblast differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers.


name: positive regulation of systemic acquired resistance

description: Any process that activates or increases the frequency, rate or extent of systemic acquired resistance.


name: myeloid dendritic cell antigen processing and presentation

description: The process in which a myeloid dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.


gibberellin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators.


description: The series of molecular signals initiated by interleukin-5 binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


name: phytochrome chromophore biosynthetic process

description: The chemical reactions and pathways resulting in the formation of the phytochrome chromophore. The phytochrome chromophore is a linear tetrapyrrolic prosthetic group covalently attached to the large soluble protein phytochrome. Light absorption by the phytochrome chromophore triggers photoconversion between two spectrally distinct forms of the photoreceptor: Pr, the red light absorbing form, and Pfr, the far red light absorbing form.


myrtenol dehydrogenase activity

description: Catalysis of the reaction: myrtenol + O2 + 2 H+ + 2 e- = 2 H2O + myrtenal.


mRNA 3'-UTR AU-rich region binding

description: Binding to a region containing frequent adenine and uridine bases within the 3' untranslated region of a mRNA molecule or in pre-mRNA intron. The ARE-binding element consensus is UUAUUUAUU. ARE-binding proteins control the stability and/or translation of mRNAs.


name: development of primary male sexual characteristics

description: The process whose specific outcome is the progression of the primary male sexual characteristics over time, from their formation to the mature structures. The primary male sexual characteristics are the testes, and they develop in response to sex hormone secretion.


regulation of mitotic cytokinesis

description: Any process that modulates the frequency, rate or extent of mitotic cytokinesis.


name: establishment of plant organ orientation

description: The process that determines the orientation of a plant organ or tissue with reference to an axis.


cardiac neuron fate commitment

description: The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron of the heart.


response to desipramine

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desipramine stimulus.


pro-B cell differentiation

description: The process in which a precursor cell type acquires the specialized features of a pro-B cell. Pro-B cells are the earliest stage of the B cell lineage and undergo heavy chain D and J gene rearrangements, although they are not fully committed.


mannan biosynthetic process

description: The chemical reactions and pathways resulting in the formation of mannan, the main hemicellulose of soft (coniferous) wood, made up of D-mannose, D-glucose and D-galactose.


name: fatty acid beta-oxidation, unsaturated, even number

description: A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).


name: inorganic molecular entity transmembrane transporter activity

description: Enables the transfer of an inorganic molecular entity from the outside of a cell to the inside of the cell across a membrane. An inorganic molecular entity is a molecular entity that contains no carbon.


name: cellular response to catecholamine stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution.


name: eukaryotic translation initiation factor 4F complex assembly

description: The aggregation, arrangement and bonding together of a set of components to form the eukaryotic translation initiation factor 4F complex.


tRNA N-acetyltransferase activity

description: Catalysis of the reaction: a cytidine in tRNA + acetyl-CoA + ATP + H2O = ADP + an N4-acetylcytidine in tRNA + CoA + H+ + phosphate.


terpenoid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure.


name: positive regulation of oogonium development

description: Any process that activates, maintains or increases the frequency, rate or extent of oogonium development, a process that leads to the formation of a female gametangium of oomycetes, containing one or more gametes.


alcohol O-hexanoyltransferase activity

description: Catalysis of the reaction: hexanoyl-CoA + an alcohol = CoA + a hexyl ester.


name: cis-zeatin UDP glycosyltransferase activity

description: Catalysis of the reaction: UDP-alpha-D-glucose + cis-zeatin = H+ + 9-(alpha-D-glucosyl)-cis-zeatin + UDP.


regulation of platelet aggregation

description: Any process that modulates the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.


inosine kinase activity

description: Catalysis of the reaction: ATP + inosine = ADP + IMP.


description: The chemical reactions and pathways resulting in the breakdown of (+)-epi-alpha-bisabolol.


name: negative regulation of metabolic activity involved in hibernation

description: The slowing of metabolic processes to very low levels in order to conserve energy as a part of hibernation.


name: cellular biogenic amine catabolic process

description: The chemical reactions and pathways occurring at the level of individual cells resulting in the breakdown of biogenic amines, any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.


cAMP-dependent protein kinase activity

description: cAMP-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.


regulation of programmed cell death

description: Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.


name: histone H3K36 trimethyltransferase activity

description: Catalysis of the reaction: L-lysyl36-[histone H3] + 3 S-adenosyl-L-methionine = 3 H+ + N6,N6,N6-trimethyl-L-lysyl36-[histone H3] + 3 S-adenosyl-L-homocysteine. This reaction is the successive addition of three methyl groups to the lysine residue at position 36 of histone H3, producing histone H3K36me3.


name: semaphorin-plexin signaling pathway involved in neuron projection guidance

description: Any semaphorin-plexin signaling pathway that is involved in neuron projection guidance.


description: Catalysis of the reaction: 7,8-dihydro-7,8-dihydroxykynurenate + NAD+ = 7,8-dihydroxykynurenate + H+ + NADH.


name: zeaxanthin bis(beta-D-glucoside) metabolic process

description: The chemical reactions and pathways involving zeaxanthin bis(beta-D-glucoside).


description: Catalysis of the reaction: UDP-alpha-D-glucose + gypsogenin = gypsogenin-28-beta-D-glucoside + UDP.


(+)-delta-cadinene synthase activity

description: Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + (+)-delta-cadinene.


name: regulation of anterograde synaptic vesicle transport

description: Any process that modulates the frequency, rate or extent of anterograde synaptic vesicle transport.


protein C-linked glycosylation

description: A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via a C atom.


hermaphrodite somatic sex determination

description: The determination of sex and sexual phenotypes in a hermaphroditic organism's soma. An example of this is found in Caenorhabditis elegans.


name: positive regulation of DNA damage response, signal transduction by p53 class mediator

description: Any process that activates, maintains or increases the rate of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.


lymph circulation

description: The flow of lymph through the body of an animal.


name: inorganic diphosphate transmembrane transporter activity

description: Enables the transfer of inorganic diphosphate across a membrane.


name: glutamate:sodium symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glutamate(out) + Na+(out) = glutamate(in) + Na+(in).


ornithine N-benzoyltransferase activity

description: Catalysis of the reaction: L-ornithine + 2 benzoyl-CoA = N(2),N(5)-dibenzoyl-L-ornithine + 2 CoA + 2 H+.


description: The acetylation of the N-terminal methionine of proteins to form the derivative N-acetyl-L-methionine.


name: mannose to fructose-6-phosphate catabolic process

description: The chemical reactions and pathways in which mannose, the aldohexose manno-hexose, is converted to fructose-6-phosphate.


coenzyme A metabolic process

description: The chemical reactions and pathways involving coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.


5'-3' DNA/RNA helicase activity

description: Unwinding of a DNA/RNA duplex in the 5' to 3' direction, driven by ATP hydrolysis.


SCF complex assembly

description: The aggregation, arrangement and bonding together of a set of components to form the SKP1-Cullin/Cdc53-F-box protein ubiquitin ligase (SCF) complex.


name: positive regulation of acetylcholine metabolic process

description: Any process that increases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.


regulation of xylan catabolic process

description: Any process that modulates the frequency, rate or extent of xylan catabolic process.


name: positive regulation of catabolic process

description: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances.


noradrenergic neuron fate commitment

description: The process in which the developmental fate of a cell becomes restricted such that it will develop into a noradrenergic neuron.


name: positive regulation of erythrocyte differentiation

description: Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation.


mesonephric distal tubule morphogenesis

description: The process in which the anatomical structures of a mesonephric distal tubule are generated and organized. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the macula densa and extends to the mesonephric connecting tubule.


manganese ion homeostasis

description: Any process involved in the maintenance of an internal steady state of manganese ions within an organism or cell.


name: vascular associated smooth muscle cell migration

description: The orderly movement of a vascular associated smooth muscle cell from one site to another.


morphine 6-dehydrogenase activity

description: Catalysis of the reaction: morphine + NAD(P)+ = morphinone + NAD(P)H + H+.


name: iron-sulfur-molybdenum cofactor metabolic process

description: The chemical reactions and pathways involving iron-sulfur-molybdenum cofactor.


name: positive regulation of triglyceride transport

description: Any process that activates or increases the frequency, rate or extent of triglyceride transport.


cellular response to cesium ion

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cesium stimulus.


bromoxynil nitrilase activity

description: Catalysis of the reaction: 3,5-dibromo-4-hydroxybenzonitrile + 2 H2O = 3,5-dibromo-4-hydroxybenzoate + NH4. Involved in the bacterial degradation of the herbicide bromoxynil.


undecan-2-one biosynthetic process

description: The chemical reactions and pathways resulting in the formation of undecan-2-one.


dCTP deaminase activity

description: Catalysis of the reaction: dCTP + H2O = dUTP + NH3.


name: inositol hexakisphosphate 3-kinase activity

description: Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 3-diphospho-1D-myo-inositol (1,2,4,5,6)pentakisphosphate.


UDP-D-xylose metabolic process

description: The chemical reactions and pathways involving UDP-D-xylose, uridinediphosphoxylose, a substance composed of xylose in glycosidic linkage with uridine diphosphate.


name: adenylate cyclase-activating G protein-coupled bile acid receptor signaling pathway

description: An adenylate cyclase-activating G protein-coupled receptor signaling pathway initiated by a ligand binding to a bile acid receptor on the surface of the target cell, and ending with the regulation of a downstream cellular process.


protein localization to nucleoplasm

description: A process in which a protein is transported to, or maintained in, a location within the nucleoplasm.


cell differentiation in hindbrain

description: The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate.


stilbene catabolic process

description: The chemical reactions and pathways resulting in the breakdown of stilbenes, a class of polyketide compounds formed from cinnamic acid and three molecules of malonyl CoA.


thiocyanate metabolic process

description: The chemical reactions and pathways involving thiocyanate, the anion of thiocyanic acid, a toxic cyanide derivative commonly formed as a by-product in the production of gas for fuel, coke, and substances for chemical industries.


peptidyl-lysine methylation

description: The methylation of peptidyl-lysine to form either the mono-, di- or trimethylated derivative.


name: positive regulation of acute inflammatory response to non-antigenic stimulus

description: Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus.