name: (3R)-hydroxyacyl-CoA dehydrogenase (NAD+) activity

description: Catalysis of the reaction: 3R-hydroxyacyl-CoA + NAD+ = 3-oxoacyl-CoA + NADH.


name: regulation of transcription-coupled nucleotide-excision repair

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Any process that modulates the frequency, rate, or extent of the nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway.


name: regulation of nucleotide-excision repair

description: Any process that modulates the frequency, rate or extent of nucleotide-excision repair.


name: cholesterol biosynthetic process via desmosterol

description: The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate desmosterol.


name: cholesterol biosynthetic process via 24,25-dihydrolanosterol

description: The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate 24,25-dihydrolanosterol.


proline racemase activity

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Catalysis of the reaction: L-proline = D-proline.


name: modulation by symbiont of host protein localization to phagocytic vesicle

description: Any process in which an organism modulates the frequency, rate or extent of protein localisation to the host phagosome. The host is defined as the larger of the organisms involved in a symbiotic interaction.


cellular hypotonic salinity response

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.


hypotonic salinity response

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.


mutator focus

category: biolink:CellularComponent biolink:AnatomicalEntity biolink:PhysicalEssence biolink:OrganismalEntity biolink:SubjectOfInvestigation biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: A type of punctate focus localized to the perinuclear region of germline cytoplasm in C. elegans. Mutator foci are required for RNA interference (RNAi) and serve as sites of small inhibitory RNA (siRNA) amplification. As such, proteins that localize to mutator foci include RNA-directed RNA polymerases (RdRPs) and beta-nucleotidyltransferases. Mutator foci are distinct from, but adjacent to or partially overlap, P granules.


description: Catalysis of the reaction: 6-hydroxynicotinate + H2O + O2 = 2,6-dihydroxynicotinate + H2O2.


regulation of type IIa hypersensitivity

description: Any process that modulates the frequency, rate, or extent of type IIa hypersensitivity, a type of inflammatory response.


name: regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains

description: Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata.


name: negative regulation of type IIa hypersensitivity

description: Any process that stops, prevents, or reduces the rate of type IIa hypersensitivity, a type of inflammatory response.


name: negative regulation of tolerance induction to nonself antigen

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to nonself antigen.


name: positive regulation of T-helper 17 cell differentiation

description: Any process that activates or increases the frequency, rate or extent of T-helper 17 cell differentiation.


name: negative regulation of T-helper 1 cell differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 1 cell differentiation.


name: negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata.


regulation of type III hypersensitivity

description: Any process that modulates the frequency, rate, or extent of type III hypersensitivity, a type of inflammatory response.


name: positive regulation of humoral immune response mediated by circulating immunoglobulin

description: Any process that activates or increases the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin.


name: positive regulation of B cell mediated immunity

description: Any process that activates or increases the frequency, rate, or extent of B cell mediated immunity.


name: positive regulation of germinal center formation

description: Any process that activates or increases the frequency, rate, or extent of germinal center formation.


name: regulation of T cell antigen processing and presentation

description: Any process that modulates the frequency, rate, or extent of T cell antigen processing and presentation.


name: negative regulation of tolerance induction dependent upon immune response

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction dependent upon immune response.


regulation of type IV hypersensitivity

description: Any process that modulates the frequency, rate, or extent of type IV hypersensitivity, a type of inflammatory response.


name: positive regulation of T cell antigen processing and presentation

description: Any process that activates or increases the frequency, rate, or extent of T cell antigen processing and presentation.


name: regulation of T-helper 17 cell differentiation

description: Any process that modulates the frequency, rate or extent of T-helper 17 cell differentiation.


name: positive regulation of complement activation, classical pathway

description: Any process that activates or increases the frequency, rate or extent of complement activation by the classical pathway.


name: regulation of antibody-dependent cellular cytotoxicity

description: Any process that modulates the frequency, rate, or extent of antibody-dependent cellular cytotoxicity.


name: positive regulation of type II hypersensitivity

description: Any process that activates or increases the frequency, rate, or extent of type II hypersensitivity.


name: negative regulation of B cell antigen processing and presentation

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell antigen processing and presentation.


name: regulation of immunoglobulin mediated immune response

description: Any process that modulates the frequency, rate, or extent of an immunoglobulin mediated immune response.


name: negative regulation of humoral immune response mediated by circulating immunoglobulin

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin.


regulation of T cell mediated immunity

description: Any process that modulates the frequency, rate, or extent of T cell mediated immunity.


name: positive regulation of type IIa hypersensitivity

description: Any process that activates or increases the frequency, rate or extent of type IIa hypersensitivity, a type of inflammatory response.


name: regulation of tolerance induction to nonself antigen

description: Any process that modulates the frequency, rate, or extent of tolerance induction to nonself antigen.


name: positive regulation of T-helper 1 cell differentiation

description: Any process that activates or increases the frequency, rate or extent of T-helper 1 cell differentiation.


regulation of germinal center formation

description: Any process that modulates the frequency, rate, or extent of germinal center formation.


name: positive regulation of T cell mediated immunity

description: Any process that activates or increases the frequency, rate, or extent of T cell mediated immunity.


name: positive regulation of B cell antigen processing and presentation

description: Any process that activates or increases the frequency, rate, or extent of B cell antigen processing and presentation.


name: negative regulation of type IIb hypersensitivity

description: Any process that stops, prevents, or reduces the rate of type IIb hypersensitivity, a type of inflammatory response.


name: positive regulation of T-helper 17 type immune response

description: Any process that activates or increases the frequency, rate or extent of T-helper 17 type immune response.


name: regulation of tolerance induction dependent upon immune response

description: Any process that modulates the frequency, rate, or extent of tolerance induction dependent upon immune response.


name: negative regulation of T-helper 17 cell lineage commitment

description: Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell lineage commitment.


name: helper T cell enhancement of B cell mediated immune response

description: Positive regulation of a B cell mediated immune response mediated via cytokine production by a helper T cell.


name: positive regulation of type IIb hypersensitivity

description: Any process that activates or increases the frequency, rate or extent of type IIb hypersensitivity, a type of inflammatory response.


name: regulation of B cell antigen processing and presentation

description: Any process that modulates the frequency, rate, or extent of B cell antigen processing and presentation.


name: negative regulation of type II hypersensitivity

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of type II hypersensitivity.


regulation of type I hypersensitivity

description: Any process that modulates the frequency, rate, or extent of type I hypersensitivity, a type of inflammatory response.


name: negative regulation of immunoglobulin mediated immune response

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of an immunoglobulin mediated immune response.


name: regulation of humoral immune response mediated by circulating immunoglobulin

description: Any process that modulates the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin.


name: negative regulation of T cell antigen processing and presentation

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell antigen processing and presentation.


name: regulation of T-helper 17 cell lineage commitment

description: Any process that modulates the frequency, rate or extent of T-helper 17 cell lineage commitment.


name: positive regulation of peripheral tolerance induction

description: Any process that activates or increases the frequency, rate, or extent of peripheral tolerance induction.


name: negative regulation of T-helper 17 cell differentiation

description: Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell differentiation.


name: negative regulation of T cell mediated immunity

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated immunity.


name: positive regulation of tolerance induction to nonself antigen

description: Any process that activates or increases the frequency, rate, or extent of tolerance induction to nonself antigen.


name: helper T cell enhancement of T cell mediated immune response

description: Positive regulation of a T cell mediated immune response mediated via cytokine production by a helper T cell.


name: regulation of complement activation, classical pathway

description: Any process that modulates the frequency, rate or extent of the classical pathway of complement activation.


name: regulation of T-helper 1 type immune response

description: Any process that modulates the frequency, rate, or extent of a T-helper 1 type immune response.


name: negative regulation of antibody-dependent cellular cytotoxicity

description: Any process that stops, prevents, or reduces the rate of antibody-dependent cellular cytotoxicity.


name: positive regulation of T-helper 1 type immune response

description: Any process that activates or increases the frequency, rate, or extent of a T-helper 1 type immune response.


name: negative regulation of B cell mediated immunity

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell mediated immunity.


name: regulation of peripheral tolerance induction

description: Any process that modulates the frequency, rate, or extent of peripheral tolerance induction.


regulation of type II hypersensitivity

description: Any process that modulates the frequency, rate, or extent of type II hypersensitivity.


name: positive regulation of tolerance induction dependent upon immune response

description: Any process that activates or increases the frequency, rate, or extent of tolerance induction dependent upon immune response.


name: negative regulation of T cell mediated cytotoxicity

description: Any process that stops, prevents, or reduces the rate of T cell mediated cytotoxicity.


name: susceptibility to T cell mediated cytotoxicity

description: The process of causing a cell to become susceptible to T cell mediated cytotoxicity.


name: regulation of T cell mediated cytotoxicity

description: Any process that modulates the frequency, rate, or extent of T cell mediated cytotoxicity.


name: regulation of T-helper 1 cell differentiation

description: Any process that modulates the frequency, rate or extent of T-helper 1 cell differentiation.


name: negative regulation of type III hypersensitivity

description: Any process that stops, prevents, or reduces the rate of type III hypersensitivity, a type of inflammatory response.


name: negative regulation of type I hypersensitivity

description: Any process that stops, prevents, or reduces the rate of type I hypersensitivity, a type of inflammatory response.


regulation of type IIb hypersensitivity

description: Any process that modulates the frequency, rate, or extent of type IIb hypersensitivity, a type of inflammatory response.


name: positive regulation of type IV hypersensitivity

description: Any process that activates or increases the frequency, rate or extent of type IV hypersensitivity, a type of inflammatory response.


name: positive regulation of type III hypersensitivity

description: Any process that activates or increases the frequency, rate or extent of type III hypersensitivity, a type of inflammatory response.


name: helper T cell enhancement of adaptive immune response

description: Positive regulation of an adaptive immune response mediated via cytokine production by helper T cell.


name: negative regulation of peripheral tolerance induction

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral tolerance induction.


name: negative regulation of germinal center formation

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of germinal center formation.


name: positive regulation of type I hypersensitivity

description: Any process that activates or increases the frequency, rate or extent of type I hypersensitivity, a type of inflammatory response.


regulation of B cell mediated immunity

description: Any process that modulates the frequency, rate, or extent of B cell mediated immunity.


name: positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains

description: Any process that activates or increases the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata.


name: regulation of T-helper 17 type immune response

description: Any process that modulates the frequency, rate or extent of T-helper 17 type immune response.


name: negative regulation of type IV hypersensitivity

description: Any process that stops, prevents, or reduces the rate of type IV hypersensitivity, a type of inflammatory response.


name: negative regulation of T-helper 1 type immune response

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of a T-helper 1 type immune response.


name: negative regulation of T-helper 17 type immune response

description: Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 type immune response.


amyloid-beta clearance

description: The process in which amyloid-beta is removed from extracellular brain regions by mechanisms involving cell surface receptors.


sialic acid:proton symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sialate(out) + H+(out) = sialate(in) + H+(in).


name: caste determination, influence by genetic factors

description: The process in which individuals, having the potential to develop any of several distinct developmental paths, have their individual developmental fate determined in response to genetic cues. Individuals with distinct developmental fates perform different functions in a colony of social insects.


polyphenic determination

description: The process in which individuals that have the potential to develop any of several possible distinct developmental paths have their individual developmental fates determined in response to environmental and/or genetic cues.


caste determination

description: The process in which individuals, having the potential to develop any of several distinct developmental paths, have their individual developmental fate determined in response to environmental and/or genetic cues. Individuals with distinct developmental fates perform different functions in a colony of social insects.


name: polyphenic determination, influence by environmental factors

description: The process in which individuals that have the potential to develop any of several possible distinct developmental paths have their individual developmental fates determined in response to environmental cues.


name: caste determination, influence by environmental factors

description: The process in which individuals, having the potential to develop any of several distinct developmental paths, have their individual developmental fate determined in response to environmental cues. Individuals with distinct developmental fates perform different functions in a colony of social insects.


name: polyphenic determination, influence by genetic factors

description: The process in which individuals that have the potential to develop any of several possible distinct developmental paths have their individual developmental fates determined in response to genetic cues.


name: copper-nicotianamine transmembrane transporter activity

description: Enables the transfer of the copper chelate copper-nicotianamine (Cu-NA) from one side of a membrane to the other.


name: regulation of somatic stem cell division

description: Any process that modulates the frequency, rate or extent of somatic stem cell division.


name: positive regulation of somatic stem cell division

description: Any process that activates or increases the frequency, rate or extent of somatic stem cell division.


name: negative regulation of somatic stem cell division

description: Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell division.


epinephrine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.


plastoglobule

description: A lipoprotein particle present in chloroplasts. They are rich in non-polar lipids (triglycerides, esters) as well as in prenylquinones, plastoquinone and tocopherols. Plastoglobules are often associated with thylakoid membranes, suggesting an exchange of lipids with thylakoids.


Fused-Smurf ubiquitin ligase complex

description: A ubiquitin ligase complex. In D. melanogaster, it regulates ubiquitination and proteolysis of the BMP receptor Thickveins in cystoblasts, potentially by controlling Tkv ubiquitination and degradation.


description: Catalysis of the reaction: S-adenosyl-L-methionine + O-demethylpuromycin = S-adenosyl-L-homocysteine + puromycin.


citrate (Si)-synthase activity

description: Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA, where the acetyl group is added to the si-face of oxaloacetate; acetyl-CoA thus provides the two carbon atoms of the pro-S carboxymethyl group.


citrate synthase activity

description: Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA.


citrate (Re)-synthase activity

description: Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA, where the acetyl group is added to the re-face of oxaloacetate; acetyl-CoA provides the two carbon atoms of the pro-R carboxymethyl group.


name: modulation of relaxation of smooth muscle in another organism

description: The process in which an organism effects a change in the relaxation of smooth muscle in a second organism.


name: positive regulation of relaxation of uterine smooth muscle in another organism

description: The process in which an organism increases the extent of relaxation of smooth muscle in the uterus of a second organism.


name: modulation of relaxation of uterine smooth muscle in another organism

description: The process in which an organism effects a change in the relaxation of smooth muscle in the uterus of a second organism.


translation at presynapse

description: Translation that occurs at the presynapse.


name: translation at presynapse, modulating chemical synaptic transmission

description: Translation that occurs at the presynapse, and that modulates chemical synaptic transmission.


name: negative regulation of oxidoreductase activity

description: Any process that stops or reduces the rate of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered.


name: negative regulation of glutathione peroxidase activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of glutathione peroxidase activity.


name: negative regulation of NAD(P)H oxidase activity

description: Any process that stops or reduces the activity of the enzyme NAD(P)H oxidase.


name: negative regulation of thioredoxin peroxidase activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of thioredoxin peroxidase activity.


name: negative regulation of tyrosinase activity

description: Any process that stops or reduces the activity of a tyrosinase enzyme.


name: negative regulation of pyruvate dehydrogenase activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of pyruvate dehydrogenase activity.


name: negative regulation of malate dehydrogenase (decarboxylating) (NADP+) activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of malate dehydrogenase (decarboxylating) (NADP+) activity.


name: negative regulation of monooxygenase activity

description: Any process that stops or reduces the activity of a monooxygenase.


name: negative regulation of succinate dehydrogenase activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of succinate dehydrogenase activity.


name: negative regulation of heme oxygenase activity

description: Any process that stops, prevents, or reduces the frequency or rate of heme oxygenase activity.


name: negative regulation of primary amine oxidase activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of primary amine oxidase activity.


name: negative regulation of cytokinin dehydrogenase activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of cytokinin dehydrogenase activity.


name: negative regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of methylenetetrahydrofolate reductase (NAD(P)H) activity.


name: negative regulation of peroxidase activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of peroxidase activity.


name: negative regulation of D-amino-acid oxidase activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of D-amino-acid oxidase activity.


name: regulation of advanced glycation end-product receptor activity

description: Any process that modulates the frequency, rate or extent of advanced glycation end-product receptor activity.


name: negative regulation of advanced glycation end-product receptor activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of advanced glycation end-product receptor activity.


extracellular matrix of synaptic cleft

description: The portion of the extracellular matrix that lies within the synaptic cleft.


cranial suture morphogenesis

description: The process in which any suture between cranial bones is generated and organized.


coronal suture morphogenesis

description: The process in which the coronal suture is generated and organized.


frontal suture morphogenesis

description: The process in which the frontal suture is generated and organized.


lambdoid suture morphogenesis

description: The process in which the lambdoid suture is generated and organized.


sagittal suture morphogenesis

description: The process in which the sagittal suture is generated and organized.


name: positive regulation of BMP signaling pathway

description: Any process that activates or increases the frequency, rate or extent of BMP signaling pathway activity.


cellular response to L-canavanine

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-canavanine stimulus. L-canavanine is L-homoserine substituted at oxygen with a guanidino (carbamimidamido) group.


response to L-canavanine

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-canavanine stimulus.


name: positive regulation of odontogenesis of dentin-containing tooth

description: Any process that activates or increases the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages that are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates.


positive regulation of odontogenesis

description: Any process that activates or increases the frequency, rate or extent of the formation and development of a tooth or teeth.


name: positive regulation of dentin-containing tooth bud formation by mesenchymal-epithelial signaling

description: Any process that initiates the formation of a tooth bud by the secretion of a signal from a mesenchymal cell and its reception and subsequent change in the identity of an epithelial cell of the tooth bud.


name: positive regulation of cardiac muscle cell apoptotic process

description: Any process that increases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.


name: cellular response to phosphate starvation

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of phosphate.


description: Catalysis of the reaction: choline + O2 = betaine aldehyde + hydrogen peroxide.


D-nopaline dehydrogenase activity

description: Catalysis of the reaction: N2-(D-1,3-dicarboxypropyl)-L-arginine + NADP+ + H2O = L-arginine + 2-oxoglutarate + NADPH.


keratinization

description: The process in which the cytoplasm of the outermost cells of the vertebrate epidermis is replaced by keratin. Keratinization occurs in the stratum corneum, feathers, hair, claws, nails, hooves, and horns.


name: mesenchymal to epithelial transition involved in renal vesicle formation

description: A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the renal vesicle.


mesenchymal to epithelial transition

description: A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell.


name: mesenchymal to epithelial transition involved in metanephric renal vesicle formation

description: A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephric renal vesicle.


name: mesenchymal to epithelial transition involved in metanephros morphogenesis

description: A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.


name: mesenchymal to epithelial transition involved in mesonephric renal vesicle formation

description: A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephric renal vesicle.


name: mesenchymal to epithelial transition involved in mesonephros morphogenesis

description: A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephros.


description: The monomethylation of the N-terminal serine of proteins to form the derivative N-methylserine.


phosphonoacetate metabolic process

description: The chemical reactions and pathways involving phosphonoacetate, C2H4PO5, a substance composed of an acetate and a phosphonic acid residue.


cspyrone B1 biosynthetic process

description: The chemical reactions and pathways resulting in the formation of cspyrone B1.


ecdysteroid 22-kinase activity

description: Catalysis of the reaction: an ecdysteroid + ATP = an ecdysteroid 22-phosphate + ADP + H+.


tartrate epimerase activity

description: Catalysis of the reaction: L-tartrate = (2R,3S)-tartrate.


bBAF complex

description: A brain-specific SWI/SNF-type complex that contains eight or nine proteins, including both conserved (core) and nonconserved components; contains the ATPase product of either the SMARCA4/BAF190A/BRG1 gene, the mammalian ortholog of the yeast SNF2 gene, or the SMARCA2/BAF190B/BRM gene, the mammalian ortholog of the Drosophila brm (brahma) gene, or an ortholog of either of these genes. Compared to the neuron-specific nBAF complex (GO:0071565) it does not contain DPF1, DPF3 or SMARCC1 or their orthologs. May contain PB1/BAF180.


GTP cyclohydrolase II activity

description: Catalysis of the reaction: GTP + 4 H2O = 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + formate + 3 H+ + 2 phosphate.


2-oxoglutarate synthase activity

description: Catalysis of the reaction: 2-oxoglutarate + CoA + oxidized ferredoxin = succinyl-CoA + CO2 + reduced ferredoxin.


(+)-2-epi-prezizaene synthase activity

description: Catalysis of the reaction: 2-cis,6-trans-farnesyl diphosphate = (+)-2-epi-prezizaene + diphosphoric acid.


name: 2-cis,6-cis-farnesyl pyrophosphate synthase activity

description: Catalysis of the reaction: dimethylallyl diphosphate + 2 isopentenyl diphosphate = 2 diphosphate + (2Z,6Z)-farnesyl diphosphate.


heart induction

description: The close range interaction between mesoderm and endoderm or ectoderm that causes cells to change their fates and specify the development of the heart.


description: Catalysis of the reaction: 5-chloro-4-hydroxy-2-oxopentanate = pyruvate + chloroacetaldehyde.


description: Catalysis of the transfer of a beta-D-GlcNAc residue from UDP-D-GlcNAc to the fucose residue of a fucosylated protein acceptor.


name: negative regulation of substance P receptor binding

description: Any process that stops, prevents or reduces the frequency, rate or extent of substance P receptor binding.


name: positive regulation of vascular endothelial growth factor signaling pathway

description: Any process that activates or increases the frequency, rate or extent of vascular endothelial growth factor signaling pathway.


description: Catalysis of the reaction 1,4-dihydroxy-2-naphthoyl-CoA + H2O = 1,4-dihydroxy-2-naphthoate + CoA + H+.


toluene oxidation via 4-hydroxytoluene

description: The degradation of toluene to form p-hydroxybenzoate; the first step in the pathway is the oxidation of toluene to form 4-hydroxytoluene (4-cresol).


toluene metabolic process

description: The chemical reactions and pathways involving toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products such as gasoline and commonly used as a paint thinning agent and in other solvent applications.


toluene oxidation to catechol

description: The formation from toluene of catechol, dihydroxybenzene, by successive oxidations followed by loss of carbon dioxide (CO2).


toluene oxidation

description: The chemical reactions and pathways resulting in the loss of electrons from one or more atoms in toluene.


anaerobic toluene metabolic process

description: The chemical reactions and pathways involving toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products, that occur in the absence of oxygen.


toluene oxidation via 2-hydroxytoluene

description: The degradation of toluene to form pyruvate and acetaldehyde; the first step in the pathway is the oxidation of toluene to form 2-hydroxytoluene (o-cresol).


toluene oxidation via 3-hydroxytoluene

description: The degradation of toluene to form pyruvate and acetaldehyde; the first step in the pathway is the oxidation of toluene to form 3-hydroxytoluene (m-cresol).


name: toluene oxidation via toluene-cis-1,2-dihydrodiol

description: The degradation of toluene to form pyruvate and acetaldehyde; the first step in the pathway is the oxidation of toluene to form toluene-cis-1,2-dihydrodiol.


toluene catabolic process

description: The chemical reactions and pathways resulting in the breakdown of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products.


anaerobic toluene catabolic process

description: The chemical reactions and pathways resulting in the breakdown of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products, in the absence of oxygen.


name: negative regulation of amacrine cell differentiation

description: Any process that stops, prevents or reduces the frequency, rate or extent of amacrine cell differentiation.


name: regulation of amacrine cell differentiation

description: Any process that modulates the frequency, rate or extent of amacrine cell differentiation.


name: positive regulation of amacrine cell differentiation

description: Any process that activates or increases the frequency, rate or extent of amacrine cell differentiation.


muscle myosin complex

description: A filament of myosin found in a muscle cell of any type.


description: Catalysis of the reaction: 4-chlorobenzoyl-CoA + chloride + NADP+ = 2,4-dichlorobenzoyl-CoA + NADPH.


description: Catalysis of the reaction: 4-sulfobenzoate + H+ + NADH + O2 = 3,4-dihydroxybenzoate + NAD+ + sulfite.


alphaIIb-beta3 integrin-ICAM-4 complex

description: A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell adhesion molecule ICAM-4.


name: lateral sprouting involved in mammary gland duct morphogenesis

description: The process in which a branch forms along the side of a mammary duct.


name: negative regulation of androgen secretion

description: Any process that stops, prevents or reduces the frequency, rate or extent of androgen secretion.


negative regulation of secretion

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.


negative regulation of defecation

description: Any process that stops, prevents or reduces the frequency, rate or extent of defecation.


name: negative regulation of defecation rhythm

description: Any process that stops, prevents or reduces the frequency, rate or extent of defecation rhythm.


name: negative regulation of thyroid-stimulating hormone secretion

description: Any process that stops, prevents or reduces the frequency, rate or extent of thyroid-stimulating hormone secretion.


name: negative regulation of glucagon secretion

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of glucagon.


name: negative regulation of luteinizing hormone secretion

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of luteinizing hormone.


name: negative regulation of ecdysteroid secretion

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of ecdysteroid.


name: negative regulation of substance P secretion

description: Any process that stops, prevents or reduces the frequency, rate or extent of substance P secretion.


name: negative regulation of neurotransmitter secretion

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter.


name: negative regulation of corticosterone secretion

description: Any process that stops, prevents or reduces the frequency, rate or extent of corticosterone secretion.


name: negative regulation of follicle-stimulating hormone secretion

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of follicle-stimulating hormone.


name: negative regulation of histamine secretion by mast cell

description: Any process that stops, prevents or reduces the frequency, rate or extent of histamine secretion by mast cell.


name: negative regulation of androstenedione secretion

description: Any process that stops, prevents or reduces the frequency, rate or extent of androstenedione secretion.


name: negative regulation of renal sodium excretion

description: Any process that decreases the amount of sodium excreted in urine over a unit of time.


name: negative regulation of renal sodium excretion by angiotensin

description: The process in which angiotensin decreases the amount of sodium that is excreted in urine over a unit of time.


name: negative regulation of testosterone secretion

description: Any process that stops, prevents or reduces the frequency, rate or extent of testosterone secretion.


name: negative regulation of epinephrine secretion

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of epinephrine.


name: negative regulation of glutamate secretion, neurotransmission

description: Any process that stops, prevents or reduces the frequency, rate or extent of glutamate secretion, neurotransmission.


name: negative regulation of gastrin-induced gastric acid secretion

description: Any process that stops, prevents or reduces the frequency, rate or extent of gastrin-induced gastric acid secretion.


name: negative regulation of dehydroepiandrosterone secretion

description: Any process that stops, prevents or reduces the frequency, rate or extent of dehydroepiandrosterone secretion.


name: negative regulation of estradiol secretion

description: Any process that stops, prevents or reduces the frequency, rate or extent of estradiol secretion.


name: negative regulation of bile acid secretion

description: Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue.


negative regulation of saliva secretion

description: Any process that stops, prevents or reduces the frequency, rate or extent of saliva secretion.


name: negative regulation of progesterone secretion

description: Any process that stops, prevents or reduces the frequency, rate or extent of progesterone secretion.


name: negative regulation of activin secretion

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of activin from a cell.


name: negative regulation of pancreatic juice secretion

description: Any process that decreases the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine.


name: negative regulation of icosanoid secretion

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of an icosanoid from a cell.


name: negative regulation of dopamine secretion

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of dopamine.


name: negative regulation of growth hormone secretion

description: Any process that decreases or stops the frequency, rate or extent of the regulated release of growth hormone from a cell.


name: negative regulation of glycine secretion, neurotransmission

description: Any process that stops, prevents or reduces the frequency, rate or extent of glycine secretion, neurotransmission.


name: negative regulation of glucocorticoid secretion

description: Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid secretion.


name: negative regulation of serotonin secretion

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of serotonin.


name: negative regulation of substance P secretion, neurotransmission

description: Any process that stops, prevents or reduces the frequency, rate or extent of substance P secretion, neurotransmission.


name: negative regulation of corticosteroid hormone secretion

description: Any process that stops, prevents or reduces the frequency, rate or extent of corticosteroid hormone secretion.


name: negative regulation of estrogen secretion

description: Any process that stops, prevents or reduces the frequency, rate or extent of estrogen secretion.


name: negative regulation of somatostatin secretion

description: Any process that decreases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas.


name: negative regulation of aldosterone secretion

description: Any process that stops, prevents or reduces the frequency, rate or extent of aldosterone secretion.


name: negative regulation of aspartate secretion

description: Any process that stops, prevents or reduces the frequency, rate or extent of aspartate secretion.


name: negative regulation of corticotropin-releasing hormone secretion

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of corticotropin-releasing hormone from a cell.


name: negative regulation of hormone secretion

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a hormone from a cell.


name: negative regulation of secretion by cell

description: Any process that stops, prevents or reduces the frequency, rate or extent of secretion by cell.


name: negative regulation of peptide hormone secretion

description: Any process that decreases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules.


name: negative regulation of glutamate secretion

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of glutamate.


name: negative regulation of calcitonin secretion

description: Any process that stops, prevents or reduces the frequency, rate or extent of calcitonin secretion.


name: negative regulation of gastric acid secretion

description: Any process that decreases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.


negative regulation of mucus secretion

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of mucus from a cell or a tissue.


name: negative regulation of spontaneous neurotransmitter secretion

description: Any process that stops, prevents or reduces the frequency, rate or extent of spontaneous neurotransmitter secretion.


name: negative regulation of parathyroid hormone secretion

description: Any process that stops, prevents or reduces the frequency, rate or extent of parathyroid hormone secretion.


name: negative regulation of peptide secretion

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion.


name: negative regulation of mineralocorticoid secretion

description: Any process that stops, prevents or reduces the frequency, rate or extent of mineralocorticoid secretion.


name: negative regulation of inhibin secretion

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of inhibin from a cell.


name: negative regulation of steroid hormone secretion

description: Any process that stops, prevents or reduces the frequency, rate or extent of steroid hormone secretion.


name: negative regulation of corticotropin secretion

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of corticotropic hormone from a cell.


name: negative regulation of gamma-aminobutyric acid secretion

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of gamma-aminobutyric acid.


name: negative regulation of estrone secretion

description: Any process that stops, prevents or reduces the frequency, rate or extent of estrone secretion.


name: negative regulation of gonadotropin secretion

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a gonadotropin.


name: negative regulation of cortisol secretion

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of cortisol from a cell.


name: negative regulation of arachidonic acid secretion

description: Any process that stops, prevents or reduces the frequency, rate or extent of arachidonic acid secretion.


name: negative regulation of juvenile hormone secretion

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of juvenile hormone.


name: negative regulation of catecholamine secretion

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a catecholamine.


description: Any process that activates or increases the frequency, rate or extent of positive regulation of 5-methylcytosine DNA demethylation, direct 5-methylcytosine excision pathway.


name: signal transduction involved in regulation of gene expression

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a signal is released and/or conveyed from one location to another.


description: Catalysis of the reaction: S-adenosyl-L-methionine + anthranilate = N-methylanthranilate + S-adenosyl-L-homocysteine + H+.


sequestering of calcium ion

description: The process of binding or confining calcium ions such that they are separated from other components of a biological system.


name: negative regulation of midbrain dopaminergic neuron differentiation

description: Any process that stops, prevents or reduces the frequency, rate or extent of midbrain dopaminergic neuron differentiation.


name: negative regulation of dopaminergic neuron differentiation

description: Any process that stops, prevents or reduces the frequency, rate or extent of dopaminergic neuron differentiation.


name: unsaturated chondroitin disaccharide hydrolase activity

description: Catalysis of the reaction: beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GalpNAc6S + H2O = 5-dehydro-4-deoxy-D-glucuronate + N-acetyl-beta-D-galactosamine 6-sulfate.


catagen

description: The regression phase of the hair cycle during which cell proliferation ceases, the hair follicle shortens, and an anchored club hair is produced.


hair cycle phase

description: The cyclical periods of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body.


anagen

description: The growth phase of the hair cycle. Lasts, for example, about 3 to 6 years for human scalp hair.


exogen

description: The shedding phase of the hair cycle.


telogen

description: The resting phase of hair cycle.


1-undecene metabolic process

description: The chemical reactions and pathways involving 1-undecene.


endothelial cell-cell adhesion

description: The attachment of an endothelial cell to another endothelial cell via adhesion molecules.


NuA4 histone acetyltransferase complex

description: A complex having histone acetylase activity on chromatin, as well as ATPase, DNA helicase and structural DNA binding activities. The complex is thought to be involved in double-strand DNA break repair. Subunits of the human complex include HTATIP/TIP60, TRRAP, RUVBL1, BUVBL2, beta-actin and BAF53/ACTL6A. In yeast, the complex has 13 subunits, including the catalytic subunit Esa1 (homologous to human Tip60).


sphingoid metabolic process

description: The chemical reactions and pathways involving sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds.


3-keto-sphinganine metabolic process

description: The chemical reactions and pathways involving 3-keto-sphinganine, a derivative of sphinganine with a ketone group at C3. It is an intermediate in the synthesis of sphingosine.


sphingosine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues.


sphinganine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of sphinganine, D-erythro-2-amino-1,3-octadecanediol.


sphinganine metabolic process

description: The chemical reactions and pathways involving sphinganine, D-erythro-2-amino-1,3-octadecanediol.


phytosphingosine metabolic process

description: The chemical reactions and pathways involving phytosphingosine, (2S,3S,4R)-2-aminooctadecane-1,3,4-triol, a constituent of many plant sphingolipids.


sphingosine metabolic process

description: The chemical reactions and pathways involving sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues.


sphingoid biosynthetic process

description: The chemical reactions and pathways resulting in the formation of sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds.


phytosphingosine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of phytosphingosine, (2S,3S,4R)-2-aminooctadecane-1,3,4-triol.


shikimate metabolic process

description: The chemical reactions and pathways involving shikimate, (3R,4S,5R)--3,4,5-trihydroxycyclohex-1-ene-1-carboxylate, the anion of shikimic acid. It is an important intermediate in the biosynthesis of aromatic amino acids.


shikimate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of shikimate, (3R,4S,5R)--3,4,5-trihydroxycyclohex-1-ene-1-carboxylate, the anion of shikimic acid.


name: heparan sulfate proteoglycan biosynthetic process, linkage to polypeptide

description: The polymerization of one or more heparan sulfate chains via a xylose link onto serine residues in the core protein of a proteoglycan.


name: response to meiotic cell cycle checkpoint signaling

description: A process that acts directly to delay or stop progression through the cell cycle in response to signals generated as a result of meiotic cell cycle checkpoint signaling; contributes to a meiotic cell cycle checkpoint.


name: response to meiotic spindle assembly checkpoint signaling

description: A process that occurs in response to signals generated as a result of meiotic spindle assembly checkpoint signaling.


name: response to meiotic DNA replication checkpoint signaling

description: A process that occurs in response to signals generated as a result of meiotic DNA replication checkpoint signaling.


L-phenylalanine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of phenylalanine, 2-amino-3-phenylpropanoic acid.


anaerobic phenylalanine oxidation

description: The chemical reactions and pathways resulting in the breakdown of phenylalanine under anaerobic conditions; occurs via the intermediates phenylpyruvate and phenylacetaldehyde.


name: cytoplasmic side of apical plasma membrane

description: The side (leaflet) of the apical region of the plasma membrane that faces the cytoplasm.


collagen type X trimer

description: A collagen homotrimer of alpha1(X) chains; type X collagen triple helices form hexagonal networks (sheets).


name: positive regulation of response to formic acid

description: Any process that activates or increases the frequency, rate or extent of response to formic acid.


regulation of response to formic acid

description: Any process that modulates the frequency, rate or extent of response to formic acid.


name: negative regulation of response to formic acid

description: Any process that stops, prevents or reduces the frequency, rate or extent of response to formic acid.


transcription factor TFIIIE complex

description: A transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIE contains a specific subset of ribosomal proteins.


name: positive regulation of vitamin metabolic process

description: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.


name: positive regulation of cobalamin metabolic process

description: Any process that activates or increases the frequency, rate or extent of a cobalamin metabolic process.


4-alpha-methyl-delta7-sterol oxidation

description: A lipid oxidation process proceeding through a series of three successive monooxygenations of the alpha methyl group on the C4 carbon (CH3 to CH2OH to CHO to COOH) and resulting in this overall reaction: 4-alpha-methyl-delta7-sterol + 3 NADPH + 3 H+ + 3 O2 = 4-alpha-carboxy,delta7-sterol + 3 NADP+ + 3 H2O.


name: regulation of protein-glutamine gamma-glutamyltransferase activity

description: Any process that modulates the frequency, rate or extent of protein-glutamine gamma-glutamyltransferase activity.


name: negative regulation of protein-glutamine gamma-glutamyltransferase activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of protein-glutamine gamma-glutamyltransferase activity.


miRNA binding

description: Binding to a microRNA, a 21-23 nucleotide RNA that is processed from a stem-loop RNA precursor (pre-miRNA) that is encoded within plant and animal genomes.


lachrymatory factor synthase activity

description: Catalysis of the reaction: 1-propenylsulfenate = propanethiol S-oxide.


name: negative regulation of gamma-delta T cell proliferation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell proliferation.


name: negative regulation of immature T cell proliferation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation.


name: negative regulation of CD4-positive, alpha-beta T cell proliferation

description: Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation.


name: negative regulation of CD8-positive, alpha-beta T cell proliferation

description: Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation.


name: negative regulation of activated T cell proliferation

description: Any process that stops, prevents or reduces the rate or extent of activated T cell proliferation.


name: negative regulation of immature T cell proliferation in thymus

description: Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation in the thymus.


name: negative regulation of T cell homeostatic proliferation

description: Any process that stops, prevents or reduces the rate or extent of resting T cell proliferation.


name: negative regulation of NK T cell proliferation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell proliferation.


name: positive regulation of centriole-centriole cohesion

description: Any process that activates or increases the frequency, rate or extent of centriole-centriole cohesion.


name: regulation of centriole-centriole cohesion

description: Any process that modulates the extent to which the two centrioles within a centrosome remain tightly paired; may be mediated by the assembly and disassembly of a proteinaceous linker.


name: negative regulation of centriole-centriole cohesion

description: Any process that stops, prevents or reduces the frequency, rate or extent of centriole-centriole cohesion.


name: negative regulation of age-related resistance

description: Any process that stops, prevents or reduces the extent of age-related resistance.


keratinocyte proliferation

description: The multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. Keratinocytes are epidermal cells which synthesize keratin and undergo a characteristic change as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin.


pericardium development

description: The process whose specific outcome is the progression of the pericardium over time, from its formation to the mature structure. The pericardium is a double-walled sac that contains the heart and the roots of the aorta, vena cava and the pulmonary artery.


description: Catalysis of the reaction: sterigmatocystin + S-adenosyl-L-methionine = 7-O-methylsterigmatocystin + S-adenosyl-homocysteine.


propanediol catabolic process

description: The chemical reactions and pathways resulting in the breakdown of propanediol, a sweet, colorless, viscous, hygroscopic liquid with the formula CH3-CHOH-CH2OH.


propanediol metabolic process

description: The chemical reactions and pathways involving propanediol, CH3-CHOH-CH2OH, a sweet, colorless, viscous, hygroscopic liquid used as an antifreeze, in brake fluid and as a humectant in cosmetics and personal care items.


name: anaerobic glycerol catabolic process to propane-1,3-diol

description: The anaerobic chemical reactions and pathways resulting in the breakdown of glycerol into propane-1,3-diol and water.


name: negative regulation of epithelial cell-cell adhesion involved in epithelium migration

description: Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell-cell adhesion involved in epithelium migration.


name: regulation of epithelial cell-cell adhesion involved in epithelium migration

description: Any process that modulates the frequency, rate or extent of epithelial cell-cell adhesion involved in epithelium migration.


name: positive regulation of epithelial cell-cell adhesion involved in epithelium migration

description: Any process that activates or increases the frequency, rate or extent of epithelial cell-cell adhesion involved in epithelium migration.


telomere single strand break repair

description: Single strand break repair that takes place in a telomere.


description: Catalysis of the addition of UDP-glucose on to asparagine-linked (N-linked) oligosaccharides of the form Man7-9GlcNAc2 on incorrectly folded glycoproteins.


name: nucleosomal methylation activator complex

description: A protein complex that contains eight subunits in common with the SWI/SNF complex, plus the ATPase BRG1 (SMARCA4) and the histone methyltransferase CARM1; the complex is involved in regulating nuclear receptor-dependent transcription.


name: negative regulation of meiotic chromosome separation

description: Any process that stops, prevents or reduces the frequency, rate or extent of meiotic chromosome separation.


posterior cibarial plate morphogenesis

description: The process in which the anatomical structures of the posterior cibarial plate are generated and organized.


sarcinapterin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of sarcinapterin.


sarcinapterin metabolic process

description: The chemical reactions and pathways involving sarcinapterin.


NADPH-cytochrome-c2 reductase activity

description: Catalysis of the reaction: NADPH + H+ + 2 ferricytochrome c2 = NADP+ + 2 ferrocytochrome c2.


name: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

description: Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced flavin or flavoprotein and one other donor, and one atom of oxygen is incorporated into one donor.


ent-kaurene oxidase activity

description: Catalysis of the reaction: H+ + NADPH + ent-kaur-16-ene + oxygen = H2O + NADP+ + ent-kaur-16-en-19-ol.


description: Catalysis of the reaction: taurochenodeoxycholate + O2 + reduced [NADPH--hemoprotein reductase] +  = taurohyocholate H+ + H2O + oxidized [NADPH--hemoprotein reductase]. Acts on taurochenodeoxycholate, taurodeoxycholate and less readily on lithocholate and chenodeoxycholate.


name: ent-kaurenoic acid monooxygenase activity

description: Catalysis of the reaction:ent-kaur-16-en-19-oate + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = gibberellin A12 + 4 H+ + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]. Catalyzes three successive oxidations of ent-kaurenoic acid.


2-hydroxyisoflavanone synthase activity

description: Catalysis of the reactions: liquiritigenin + O2 + [reduced NADPH--hemoprotein reductase] = 2,4',7-trihydroxyisoflavanone + H2O + [oxidized NADPH--hemoprotein reductase] and (2S)-naringenin + O2 + [reduced NADPH--hemoprotein reductase] = 2,4',5,7-tetrahydroxyisoflavanone + H2O + [oxidized NADPH--hemoprotein reductase].


(R)-limonene 6-monooxygenase activity

description: Catalysis of the reaction: (4R)-limonene + O2 + reduced [NADPH--hemoprotein reductase] = (1R,5S)-carveol + H+ + H2O + oxidized [NADPH--hemoprotein reductase].


name: arachidonic acid omega-hydroxylase activity

description: Catalysis of the reaction: arachidonic acid + O2 + NADPH + H+ = 20-HETE + NADP+ + H2O. Arachidonic acid is also known as (5Z,8Z,11Z,14Z)-icosatetraenoic acid, and 20-HETE is also known as (5Z,8Z,11Z,14Z)-20-hydroxyicosa-5,8,11,14-tetraenoic acid.


flavanone 2-hydroxylase activity

description: Catalysis of the reaction: a flavanone + O2 + reduced [NADPH--hemoprotein reductase] = a 2-hydroxyflavanone + H+ + H2O + oxidized [NADPH--hemoprotein reductase].


aflatoxin B synthase activity

description: Catalyzes the reaction: 8-O-methylsterigmatocystin + 2 [reduced NADPH--hemoprotein reductase] + 2 O2 = aflatoxin B + 2 [oxidized NADPH--hemoprotein reductase] + H2O + methanol + CO2. Produces both aflatoxin B(1) and aflatoxin B(2).


(S)-limonene 3-monooxygenase activity

description: Catalysis of the reaction: (4S)-limonene + O2 + reduced [NADPH--hemoprotein reductase] = (1S,6R)-isopiperitenol + H+ + H2O + oxidized [NADPH--hemoprotein reductase].


name: alkanal monooxygenase (FMN-linked) activity

description: Catalysis of the reaction: R-CHO + reduced FMN + O2 = R-COOH + FMN + H2O + light.


heme oxygenase (decyclizing) activity

description: Catalysis of the reaction: heme b + 3 O2 + 3 reduced [NADPH-hemoprotein reductase] = biliverdin + CO + Fe2+ + H+ + 3 H2O + 3 oxidized [NADPH-hemoprotein reductase].


7-deoxyloganin 7-hydroxylase activity

description: Catalysis of the reaction: 7-deoxyloganin + O2 + reduced [NADPH-hemoprotein reductase] = H+ + H2O + loganin + oxidized [NADPH-hemoprotein reductase].


indole-2-monooxygenase activity

description: Catalysis of the reaction: indole + O2 + reduced [NADPH--hemoprotein reductase] = H+ + H2O + indolin-2-one + oxidized [NADPH--hemoprotein reductase].


description: Catalysis of the reaction: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMNH2 + O2 = 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMN + H2O.


description: Catalysis of the reaction: leukotriene B4 + O2 + reduced [NADPH-hemoprotein reductase] = 20-hydroxy-leukotriene B4 + H+ + H2O + oxidized [NADPH-hemoprotein reductase].


name: cytochrome P450 dependent beta-amyrin 16beta-hydroxylase activity

description: Catalysis of the reaction: beta-amyrin + O2 + H+ + NADPH = 16beta-hydroxy-beta-amyrin + H2O + NADP.


(S)-limonene 7-monooxygenase activity

description: Catalysis of the reaction: (4S)-limonene + O2 + reduced [NADPH--hemoprotein reductase] = (4S)-perillyl alcohol + H+ + H2O + oxidized [NADPH--hemoprotein reductase].


(S)-limonene 6-monooxygenase activity

description: Catalysis of the reaction: (4S)-limonene + O2 + reduced [NADPH--hemoprotein reductase] = (1S,5R)-carveol + H+ + H2O + oxidized [NADPH--hemoprotein reductase].


(+)-menthofuran synthase activity

description: Catalysis of the reaction: (R)-pulegone + reduced [NADPH--hemoprotein reductase] + O2 = (R)-menthofuran + 2 H2O + +H+ + oxidized [NADPH--hemoprotein reductase].


phenylacetate 2-hydroxylase activity

description: Catalysis of the reaction: 2-phenylacetate + O2 + reduced [NADPH--hemoprotein reductase] = (2-hydroxyphenyl)acetate + H+ + H2O + oxidized [NADPH--hemoprotein reductase].


sterol 12-alpha-hydroxylase activity

description: Catalysis of the reaction: a steroid + donor-H2 + O2 = 12-alpha-hydroxysteroid + H2O.


2,5-diketocamphane 1,2-monooxygenase

description: Catalysis of the reaction: 1R,4R)-bornane-2,5-dione + FMNH2 + O2 = (1R,4R)-5-oxo-1,2-campholide + FMN + H+ + H2O.


tryptophan N-monooxygenase activity

description: Catalyzes the multi-step reaction: L-tryptophan + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = (E)-(indol-3-yl)acetaldehyde oxime + CO2 + 2 H+ + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase].


3-chloro THPH synthase activity

description: Catalysis of the reaction: 2,4,6-trihydroxyphenylhexan-1-one + chloride + FADH2 + O2 = (3-chloro-2,4,6-trihydroxyphenyl)hexan-1-one + FAD + H+ + 2 H2O.


alkanesulfonate monooxygenase activity

description: Catalysis of the reaction: an alkanesulfonate + O2 + FMNH2 = an aldehyde + sulfite + H2O + FMN.


description: Catalysis of the reaction: (+)-alpha-tocopherol + O2 + reduced [NADPH--hemoprotein reductase] = 13-hydroxy-alpha-tocopherol + H+ + H2O + oxidized [NADPH--hemoprotein reductase].


fatty acid omega-1 hydroxylase activity

description: Catalysis of the reaction: an (omega-1)-ethyl fatty acid + O2 + reduced [NADPH--hemoprotein reductase] = an (omega-1)-hydroxy fatty acid + H+ + H2O + oxidized [NADPH--hemoprotein reductase].


methyl farnesoate epoxidase activity

description: Catalysis of the reaction: methyl (2E,6E)-farnesoate + O2 + reduced [NADPH--hemoprotein reductase] = H+ + H2O + juvenile hormone III + oxidized [NADPH--hemoprotein reductase].


name: (22S)-22-hydroxy-5alpha-campestan-3-one C-23 hydroxylase activity

description: Catalysis of the reaction: (5alpha,22S,24R)-22-hydroxyergostan-3-one + O2 + NADPH + H+ = 3-dehydro-6-deoxoteasterone + NADP + H2O.


description: Catalysis of the reaction: nitrilotriacetate + NADH + H+ + O2 = NAD+ + H2O + glyoxylate + iminodiacetate.


pipecolic acid N-hydroxylase

description: Catalysis of the reaction: L-pipecolic acid + NAD(P)H + O2 + H+ = N-hydroxypipecolic acid + NAD(P)+ + H2O.


description: Catalysis of the reaction: 7alpha-hydroxycholest-4-en-3-one + H+ + NADPH + O2 = 7alpha,12alpha-dihydroxycholest-4-en-3-one + H2O + NADP+.


3,5 dichloro-THPH synthase activity

description: Catalysis of the reaction: (3-chloro-2,4,6-trihydroxyphenyl)hexan-1-one + chloride + FADH2 + O2 = (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one + FAD + 2 H2O.


name: very long-chain fatty acid omega-hydroxylase activity

description: Catalysis of the reaction: an omega-methyl-very-long-chain fatty acid + O2 + reduced [NADPH-hemoprotein reductase] = an omega-hydroxy-very-long-chain fatty acid + H+ + H2O + oxidized [NADPH-hemoprotein reductase]. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons.


description: Catalysis of the reactions: cholest-5-ene-3beta,25-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,25-triol + NADP+ + H2O, and cholest-5-ene-3beta,27-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,27-triol + NADP+ + H2O.


aromatase activity

description: Catalysis of the reduction of an aliphatic ring to yield an aromatic ring.


description: Catalysis of the reaction: 5beta-cholestane-3alpha,7alpha-diol + H+ + NADPH + O2 = 5beta-cholestane-3alpha,7alpha,12alpha-triol + H2O + NADP+.


name: long-chain fatty acid omega-1 hydroxylase activity

description: Catalysis of the reaction: an (omega-1)-ethyl long-chain fatty acid + O2 + reduced [NADPH-hemoprotein reductase] = an (omega-1)-hydroxy-long-chain fatty acid + H+ + H2O + oxidized [NADPH-hemoprotein reductase. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.


thalianol hydroxylase activity

description: Catalysis of the reaction: a thalianol = a thalian-diol. This reaction is the addition of a hydroxyl group to thalianol ((13R,14R,17E)-podioda-8,17,21-trien-3beta-ol) to create a thalian-diol ((13R,14R,17E)-podioda-8,17,21-trien-3beta,X-diol), where the hydroxyl group may be attached at one of several different available carbons in ring B or C of thalianol, indicated by the X.


germacrene A hydroxylase activity

description: Catalysis of the reaction:(+)-(R)-germacrene A + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = germacra-1(10),4,11(13)-trien-12-oate + 4 H+ + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase].


description: Catalysis of the reaction: (24S)-hydroxycholesterol + O2 + reduced [NADPH-hemoprotein reductase] = (24S)-7alpha-dihydroxycholesterol + H+ + H2O + oxidized [NADPH-hemoprotein reductase].


description: Catalysis of the reaction: 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + O2 + reduced [NADPH--hemoprotein reductase] = DIBOA + H+ + H2O + oxidized [NADPH--hemoprotein reductase].


description: Catalysis of the reaction: (4-hydroxyphenyl)acetate + FADH(2) + O2 = 3,4-dihydroxyphenylacetate + FAD + H+ + H2O.


name: long-chain fatty acid omega-hydroxylase activity

description: Catalysis of the reaction: an omega-methyl-long-chain fatty acid + O2 + reduced [NADPH--hemoprotein reductase] = an omega-hydroxy-long-chain fatty acid + H+ + H2O + oxidized [NADPH--hemoprotein reductase]. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.


description: Catalysis of the reaction: 3-hydroxyindolin-2-one + O2 + reduced [NADPH--hemoprotein reductase] = 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + H+ + H2O + oxidized [NADPH--hemoprotein reductase].


name: medium-chain fatty acid omega-hydroxylase activity

description: Catalysis of the reaction: an omega-methyl-medium-chain fatty acid + O2 + reduced [NADPH--hemoprotein reductase] = an omega-hydroxy-medium-chain fatty acid + H+ + H2O + oxidized [NADPH--hemoprotein reductase]. A medium-chain fatty acid has an aliphatic tail containing 6 to 12 carbons.


fatty acid omega-hydroxylase activity

description: Catalysis of the reaction: an omega-methyl fatty acid + O2 + reduced [NADPH--hemoprotein reductase] = an omega-hydroxy fatty acid + H+ + H2O + oxidized [NADPH--hemoprotein reductase].


7-deoxyloganate 7-hydroxylase activity

description: Catalysis of the reaction: 7-deoxyloganate + O2 + reduced [NADPH-hemoprotein reductase] = H+ + H2O + loganate + oxidized [NADPH-hemoprotein reductase].


isoflavone 2'-hydroxylase activity

description: Catalysis of the reaction: an isoflavone + O2 + reduced [NADPH-hemoprotein reductase] = a 2'-hydroxyisoflavone + H+ + H2O + oxidized [NADPH-hemoprotein reductase].


linalool 8-monooxygenase activity

description: Catalysis of the reaction: linalool + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = (6E)-8-oxolinalool + 2 H+ + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase].


uvaol dehydrogenase activity

description: Catalysis of the reaction: uvaol + NADPH + O2 + H+ = ursolic aldehyde + NADP + 2 H2O.


name: medium-chain fatty acid omega-1 hydroxylase activity

description: Catalysis of the reaction: an (omega-1)-ethyl medium-chain fatty acid + O2 + reduced [NADPH-hemoprotein reductase] = an (omega-1)-hydroxy-medium-chain fatty acid + H+ + H2O + oxidized [NADPH-hemoprotein reductase. A medium-chain fatty acid has an aliphatic tail containing 6 to 12 carbons.


farnesoate epoxidase activity

description: Catalysis of the reaction: (2E,6E)-farnesoate + O2 + reduced [NADPH--hemoprotein reductase] = H+ + H2O + juvenile hormone III carboxylate + oxidized [NADPH--hemoprotein reductase].


name: humoral immune response mediated by circulating immunoglobulin

description: An immune response dependent upon secreted immunoglobulin. An example of this process is found in Mus musculus.


Golgi cell precursor proliferation

description: The multiplication or reproduction of neuroblasts that will give rise to Golgi cells. A Golgi cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.


name: clathrin-sculpted acetylcholine transport vesicle membrane

description: The lipid bilayer surrounding a clathrin-sculpted acetylcholine transport vesicle.


sarcosine metabolic process

description: The chemical reactions and pathways involving sarcosine.


sarcosine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of sarcosine.


sarcosine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of sarcosine.


L-amino acid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of an L-amino acid.


3-cyano-L-alanine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of 3-cyano-L-alanine.


AGA codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes an AGA codon.


name: negative regulation of cell proliferation involved in heart valve morphogenesis

description: Any process that decreases the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve.


name: regulation of cell proliferation involved in heart valve morphogenesis

description: Any process that modulates the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve.


name: positive regulation of cell proliferation involved in heart valve morphogenesis

description: Any process that increases the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve.


regulation of binding

description: Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.


regulation of mRNA cap binding

description: Any process that modulates the frequency, rate or extent of mRNA cap binding.


regulation of chromatin binding

description: Any process that modulates the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.


regulation of receptor binding

description: Any process that modulates the frequency, rate or extent of a protein or other molecule binding to a receptor.


name: negative regulation of transferrin receptor binding

description: Any process that stops, prevents or reduces the frequency, rate or extent of transferrin receptor binding.


name: negative regulation of selenocysteine insertion sequence binding

description: Any process that stops, prevents or reduces the frequency, rate or extent of selenocysteine insertion sequence binding.


name: negative regulation of apolipoprotein binding

description: Any process that stops, prevents or reduces the frequency, rate or extent of apolipoprotein binding.


regulation of small GTPase binding

description: Any process that modulates the frequency, rate or extent of small GTPase binding.


regulation of actin binding

description: Any process that modulates the frequency, rate or extent of actin binding.


name: regulation of heparan sulfate proteoglycan binding

description: Any process that modulates the frequency, rate or extent of heparan sulfate proteoglycan binding.


regulation of ferrous iron binding

description: Any process that modulates the frequency, rate or extent of ferrous iron binding.


negative regulation of lipid binding

description: Any process that stops, prevents or reduces the frequency, rate or extent of lipid binding.


regulation of C-C chemokine binding

description: Any process that modulates the frequency, rate or extent of C-C chemokine binding.


name: regulation of RNA polymerase II regulatory region sequence-specific DNA binding

description: Any process that modulates the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding.


regulation of protein binding

description: Any process that modulates the frequency, rate or extent of protein binding.


name: regulation of transferrin receptor binding

description: Any process that modulates the frequency, rate or extent of transferrin receptor binding.


regulation of core promoter binding

description: Any process that modulates the frequency, rate or extent of core promoter binding.


name: regulation of transcription regulatory region DNA binding

description: Any process that modulates the frequency, rate or extent of transcription regulatory region DNA binding.


name: negative regulation of C-C chemokine binding

description: Any process that stops, prevents or reduces the frequency, rate or extent of C-C chemokine binding.


negative regulation of actin binding

description: Any process that stops, prevents or reduces the frequency, rate or extent of actin binding.


name: regulation of selenocysteine insertion sequence binding

description: Any process that modulates the frequency, rate or extent of selenocysteine insertion sequence binding.


name: negative regulation of chemokine activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of chemokine activity.


name: regulation of microtubule plus-end binding

description: Any process that modulates the frequency, rate or extent of microtubule plus-end binding.


regulation of GTP binding

description: Any process that modulates the frequency, rate or extent of GTP binding.


name: negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding

description: Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding.


regulation of calcium ion binding

description: Any process that modulates the frequency, rate or extent of calcium ion binding.


regulation of mRNA binding

description: Any process that modulates the frequency, rate or extent of mRNA binding.


name: negative regulation of double-stranded telomeric DNA binding

description: Any process that stops, prevents or reduces the frequency, rate or extent of double-stranded telomeric DNA binding.


name: negative regulation of microtubule binding

description: Any process that stops, prevents or reduces the frequency, rate or extent of microtubule binding.


name: negative regulation of growth hormone activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of growth hormone activity.


negative regulation of mRNA cap binding

description: Any process that stops, prevents or reduces the frequency, rate or extent of mRNA cap binding.


name: negative regulation of core promoter binding

description: Any process that stops, prevents or reduces the frequency, rate or extent of core promoter binding.


name: regulation of microtubule minus-end binding

description: Any process that modulates the frequency, rate or extent of microtubule minus-end binding.


negative regulation of collagen binding

description: Any process that stops, prevents, or reduces the frequency, rate or extent of collagen binding.


name: negative regulation of G-quadruplex DNA binding

description: Any process that stops, prevents or reduces the frequency, rate or extent of G-quadruplex DNA binding.


regulation of G-quadruplex DNA binding

description: Any process that modulates the frequency, rate or extent of G-quadruplex DNA binding.


name: regulation of single-stranded telomeric DNA binding

description: Any process that modulates the frequency, rate or extent of binding to single-stranded telomeric DNA.


regulation of chemokine activity

description: Any process that modulates the frequency, rate or extent of chemokine activity.


negative regulation of RNA binding

description: Any process that stops, prevents or reduces the frequency, rate or extent of RNA binding.


regulation of actin filament binding

description: Any process that modulates the frequency, rate or extent of actin filament binding.


negative regulation of protein binding

description: Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding.


regulation of apolipoprotein binding

description: Any process that modulates the frequency, rate or extent of apolipoprotein binding.


regulation of DNA binding

description: Any process that modulates the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).


regulation of telomeric DNA binding

description: Any process that modulates the frequency, rate or extent of telomeric DNA binding.


name: negative regulation of calcium ion binding

description: Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion binding.


regulation of triplex DNA binding

description: Any process that modulates the frequency, rate or extent of triplex DNA binding.


name: regulation of protein homodimerization activity

description: Any process that modulates the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer.


name: negative regulation of telomeric DNA binding

description: Any process that stops, prevents or reduces the frequency, rate or extent of telomeric DNA binding.


negative regulation of mRNA binding

description: Any process that stops, prevents or reduces the frequency, rate or extent of mRNA binding.


name: regulation of DNA replication origin binding

description: Any process that modulates the frequency, rate or extent of DNA replication origin binding.


name: negative regulation of euchromatin binding

description: Any process that stops, prevents or reduces the frequency, rate or extent of euchromatin binding.


name: negative regulation of actin filament binding

description: Any process that stops, prevents or reduces the frequency, rate or extent of actin filament binding.


regulation of cytokine activity

description: Any process that modulates the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells.


name: negative regulation of chromatin binding

description: Any process that stops or reduces the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.


name: regulation of substance P receptor binding

description: Any process that modulates the frequency, rate or extent of substance P receptor binding.


name: negative regulation of DNA replication origin binding

description: Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication origin binding.


regulation of heparan sulfate binding

description: Any process that modulates the frequency, rate or extent of heparan sulfate binding.


regulation of microtubule binding

description: Any process that modulates the frequency, rate or extent of microtubule binding.


regulation of growth hormone activity

description: Any process that modulates the frequency, rate or extent of growth hormone activity.


name: negative regulation of small GTPase binding

description: Any process that stops, prevents or reduces the frequency, rate or extent of small GTPase binding.


name: regulation of double-stranded telomeric DNA binding

description: Any process that modulates the frequency, rate or extent of double-stranded telomeric DNA binding.


name: negative regulation of heparan sulfate binding

description: Any process that stops, prevents or reduces the frequency, rate or extent of heparan sulfate binding.


regulation of euchromatin binding

description: Any process that modulates the frequency, rate or extent of euchromatin binding.


regulation of collagen binding

description: Any process that modulates the frequency, rate or extent of collagen binding.


name: negative regulation of protein homodimerization activity

description: Any process that decreases the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer.


regulation of lipid binding

description: Any process that modulates the frequency, rate or extent of lipid binding.


negative regulation of binding

description: Any process that stops or reduces the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.


regulation of mRNA 3'-UTR binding

description: Any process that modulates the frequency, rate or extent of mRNA 3'-UTR binding.


name: regulation of guanyl-nucleotide exchange factor activity

description: Any process that modulates the frequency, rate or extent of guanyl-nucleotide exchange factor activity.


name: regulation of Rho guanyl-nucleotide exchange factor activity

description: Any process that modulates the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity.


name: negative regulation of mRNA 3'-UTR binding

description: Any process that stops, prevents or reduces the frequency, rate or extent of mRNA 3'-UTR binding.


name: modulation by host of RNA binding by virus

description: A process in which a host organism modulates the frequency, rate or extent of a viral gene product binding to RNA.


name: regulation of protein heterodimerization activity

description: Any process that modulates the frequency, rate or extent of protein heterodimerization, interacting selectively with a nonidentical protein to form a heterodimer.


name: regulation of recombination hotspot binding

description: Any process that modulates the frequency, rate or extent of recombination hotspot binding.


negative regulation of receptor binding

description: Any process that stops, prevents or reduces the frequency, rate or extent of a protein or other molecule binding to a receptor.


name: negative regulation of ferrous iron binding

description: Any process that stops, prevents or reduces the frequency, rate or extent of ferrous iron binding.


name: negative regulation of heparan sulfate proteoglycan binding

description: Any process that stops, prevents or reduces the frequency, rate or extent of heparan sulfate proteoglycan binding.


name: negative regulation of transcription regulatory region DNA binding

description: Any process that stops, prevents or reduces the frequency, rate or extent of transcription regulatory region DNA binding.


name: regulation of RNA polymerase I regulatory region sequence-specific DNA binding

description: Any process that modulates the frequency, rate or extent of RNA polymerase I regulatory region sequence-specific DNA binding.


name: negative regulation of cytokine activity

description: Any process that decreases the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells.


name: negative regulation of microtubule plus-end binding

description: Any process that stops, prevents or reduces the frequency, rate or extent of microtubule plus-end binding.


name: regulation of low-density lipoprotein particle receptor binding

description: Any process that modulates the frequency, rate or extent of low-density lipoprotein particle receptor binding.


negative regulation of DNA binding

description: Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).


regulation of RNA binding

description: Any process that modulates the frequency, rate or extent of RNA binding.


name: negative regulation of triplex DNA binding

description: Any process that stops, prevents or reduces the frequency, rate or extent of triplex DNA binding.


negative regulation of GTP binding

description: Any process that stops, prevents or reduces the frequency, rate or extent of GTP binding.


name: negative regulation of RNA polymerase I regulatory region sequence-specific DNA binding

description: Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase I regulatory region sequence-specific DNA binding.


gamma-tubulin complex

description: A multiprotein complex composed of gamma-tubulin and other non-tubulin proteins. Gamma-tubulin complexes are localized to microtubule organizing centers, and play an important role in the nucleation of microtubules. The number and complexity of non-tubulin proteins associated with these complexes varies between species.


gamma-tubulin small complex

description: A complex usually comprising two gamma-tubulin molecules and two conserved non-tubulin proteins. Some gamma-tubulin small complexes are thought to be the repeating unit making up the core of the gamma-tubulin ring complex.


gamma-tubulin ring complex

description: A complex of gamma tubulin and associated proteins thought to be formed by multimerization of gamma-tubulin small complexes. An example of this structure is found in Schizosaccharomyces pombe.


nonassociative learning

description: A simple form of learning whereby the repeated presence of a stimulus leads to a change in the probability or strength of the response to that stimulus. There is no association of one type of stimulus with another, rather it is a generalized response to the environment.


dishabituation

description: The temporary recovery of response to a stimulus when a novel stimulus is added.


sensitization

description: An increased in a behavioral response to a repeated stimulus. For example, a shock to the tail of the marine snail Aplysia, to which the snail responds by withdrawing its gill, will result in increased gill withdrawal the next time the skin is touched.


habituation

description: A decrease in a behavioral response to a repeated stimulus. This is exemplified by the failure of a person to show a startle response to a loud noise that has been repeatedly presented.


D-allose biosynthetic process

description: The chemical reactions and pathways resulting in the formation of D-allose, the D-enantiomer of allo-hexose, an aldohexose similar to glucose.


name: 3,8-divinyl protochlorophyllide a 8-vinyl reductase activity

description: Catalysis of the reaction: divinyl protochlorophyllide a + NADPH + H+ = monovinyl protochlorophyllide a + NADP+.


description: Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + UDP-N-acetyl-D-galactosamine 4-sulfate = adenosine 3',5'-diphosphate + H+ + UDP-N-acetyl-D-galactosamine 4,6-disulfate.


name: CD8-positive, alpha-beta cytotoxic T cell extravasation

description: The migration of a CD8-positive, alpha-beta cytotoxic T cell from the blood vessels into the surrounding tissue.


name: CD8-positive, alpha-beta T cell extravasation

description: The migration of a CD8-positive, alpha-beta T cell from the blood vessels into the surrounding tissue.


T-helper 1 cell extravasation

description: The migration of a T-helper 1 cell from the blood vessels into the surrounding tissue. A T-helper 1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma.


T-helper 17 cell extravasation

description: The migration of a T-helper 17 cell from the blood vessels into the surrounding tissue.


3'-flap-structured DNA binding

description: Binding to a 3'-flap structure in DNA. A DNA flap structure is one in which a single-stranded 3'-end of DNA or RNA protrudes from a double-stranded DNA molecule.


spermidine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of spermidine, N-(3-aminopropyl)-1,4-diaminobutane.


name: clathrin-sculpted glutamate transport vesicle

description: A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing glutamate.


name: negative regulation of retrograde dense core granule transport

description: Any process that stops, prevents or reduces the frequency, rate or extent of retrograde dense core granule transport.


site of DNA damage

description: A region of a chromosome at which DNA damage has occurred. DNA damage signaling and repair proteins accumulate at the lesion to respond to the damage and repair the DNA to form a continuous DNA helix.


tetraspanin-enriched microdomain

description: A pre-organized unit composed either of adhesion molecules (mainly integrins and members of the Ig superfamily), signaling receptors and/or enzyme-enriched plasma membrane domains that compartmentalizes cellular processes. Tetraspanin-enriched microdomains might be specially suited for the regulation of avidity of adhesion receptors and the compartmentalization of enzymatic activities.


cellular response to streptomycin

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a streptomycin stimulus. Streptomycin is a commonly used antibiotic in cell culture media which acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome.


name: ABC-type quaternary ammonium compound transporting activity

description: Catalysis of the reaction: ATP + H2O + quaternary ammonium(out) = ADP + H+ + phosphate + quaternary ammonium(in).


name: quaternary ammonium group transmembrane transporter activity

description: Enables the transfer of quaternary ammonium groups from one side of a membrane to the other. Quaternary ammonium groups are any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups.