name: chromium ion transmembrane transporter activity

description: Enables the transfer of chromium (Cr) ions from one side of a membrane to the other.


name: purine-containing compound metabolic process

category: biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The chemical reactions and pathways involving a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof.


nicotianamine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of nicotianamine, 2(S),3'2(S),3''(S)-N-(N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl)-azetidine-2-carboxylic acid.


malonyl-CoA metabolic process

description: The chemical reactions and pathways involving malonyl-CoA, the S-malonyl derivative of coenzyme A.


lipopolysaccharide transfer activity

category: biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: Removes a lipopolysaccharide (LPS) from the outer leaflet of a donor membrane, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to the outer leaflet of an acceptor membrane.


synoviocyte proliferation

description: The multiplication or reproduction of type B synoviocytes by cell division, resulting in the expansion of their population. A type B synoviocyte is a fibroblast-like cell found in synovial tissues.


name: negative regulation of neutrophil mediated cytotoxicity

description: Any process that decreases the frequency, rate or extent of the directed killing of a target cell by a neutrophil.


hepoxilin metabolic process

description: The chemical reactions and pathways involving hepoxilins, a class of bioactive icosanoids with roles in the regulation of cell physiology.


name: negative regulation of multicellular organism growth

description: Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size.


quercetin O-glucoside metabolic process

description: The chemical reactions and pathways involving O-glucosylated derivatives of quercetin.


cellular response to methionine

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methionine stimulus.


description: Catalysis of the reaction: 5-hydroxypyrrole-2-carboxylate = 5-oxo-4,5-dihydropyrrole-2-carboxylate.


regulation of fibroblast migration

description: Any process that modulates the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.


premature acrosome loss

description: The discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents.


name: protein localization to perinuclear region of cytoplasm

description: A process in which a protein is transported to, or maintained in, a location within the perinuclear region of the cytoplasm.


TOR signaling

category: biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

description: The series of molecular signals mediated by TOR (Target of rapamycin) proteins, members of the phosphoinositide (PI) 3-kinase related kinase (PIKK) family that act as serine/threonine kinases in response to nutrient availability or growth factors.


description: Catalysis of the reaction: 5,10-methenyltetrahydrofolate + H2O = 10-formyltetrahydrofolate.


name: fucose transmembrane transporter activity

description: Enables the transfer of fucose from one side of a membrane to the other. Fucose is 6-deoxygalactose and has two enantiomers, D-fucose and L-fucose.


MutLbeta complex binding

description: Binding to a MutLbeta mismatch repair complex.


neuron cell-cell adhesion

description: The attachment of a neuron to another cell via adhesion molecules.


name: negative regulation of hexasaccharide transport

description: Any process that stops, prevents or reduces the frequency, rate or extent of hexasaccharide transport.


embryonic lung development

description: The process occurring during the embryonic phase whose specific outcome is the progression of the lung over time, from its formation to the mature structure.


forebrain neuroblast division

description: The division of a neuroblast located in the forebrain. Neuroblast division gives rise to at least another neuroblast.


taurine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats.


Ras palmitoyltransferase activity

description: Catalysis of the reaction: palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA, specific for Ras proteins.


name: abscisic acid-activated signaling pathway involved in stomatal movement

description: Any abscisic acid mediated signaling pathway that is involved in stomatal movement.


detection of gibberellic acid stimulus

description: The series of events in which a gibberellic acid stimulus is received by a cell and converted into a molecular signal.


name: rhamnogalacturonan alpha-L-rhamnopyranosyl-(1->4)-alpha-D-galactopyranosyluronide lyase activity

description: Catalysis of the cleavage of rhamnogalacturonan, generating oligosaccharides of the form alpha-D-us-galacturonic acid-(1,2)-alpha-L-rhamnose-(1,4)-alpha-D-galacturonate-(1,2)-L-rhamnose-(1,2)-alpha-L-rhamnose-p-(1,4)-alpha-D-galacturonic acid, terminating at the non-reducing end with a hex-4-enopyranosyluronic acid residue.


name: epithelial-mesenchymal cell signaling involved in lung development

description: Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell and contributes to the progression of the lung over time from its initial formation to the mature organ.


name: lysophosphatidic acid acyltransferase activity

description: Catalysis of the transfer of acyl groups from an acyl-CoA to lysophosphatidic acid to form phosphatidic acid.


floral organ development

description: The process whose specific outcome is the progression of the floral organ over time, from its formation to the mature structure.


GTP metabolic process

description: The chemical reactions and pathways involving GTP, guanosine triphosphate.


name: regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation

description: Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation.


acylglycerol homeostasis

description: Any process involved in the maintenance of an internal steady state of acylglycerol within an organism or cell.


description: Catalysis of the reaction: 2,3-dihydroxybenzoate + ATP + holo-[ACP] = 2,3-dihydroxybenzoyl-[ACP] + AMP + diphosphate.


description: Catalysis of the addition of mannose to dolichyl-pyrophosphate Man7GlcNAc2 (also written as Man7GlcNAc2-PP-Dol) in alpha-(1->6) linkage, producing Man8GlcNAc2-PP-Dol.


urethra development

description: The progression of the urethra over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body.


cellular response to estradiol stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.


cellular response to UV-C

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm.


rifamycin-B oxidase activity

description: Catalysis of the reaction: 2 H+ + O2 + rifamycin B = H2O2 + rifamycin O.


name: regulation of adult chitin-containing cuticle pigmentation

description: Any process that modulates the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism.


name: cell fate specification involved in pattern specification

description: The process involved in the specification of the identity of a cell in a field of cells that is being instructed as to how to differentiate. Once specification has taken place, that cell will be committed to differentiate down a specific pathway if left in its normal environment.


nitrile hydratase activity

description: Catalysis of the reaction: an aliphatic amide = a nitrile + H2O.


nuclear export signal receptor activity

description: Combining with a nuclear export signal (NES) on a cargo to be transported, to mediate transport of a the cargo through the nuclear pore, from the nuclear lumen to the cytoplasm. The cargo can be either a RNA or a protein.


name: pre-mRNA intronic pyrimidine-rich binding

description: Binding to a pyrimidine-rich (CU-rich) intronic sequence of a pre-messenger RNA (pre-mRNA).


cellular response to ethylene stimulus

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus.


exo-(1,4)-alpha-D-glucan lyase activity

description: Catalysis of the reaction: linear alpha-D-glucan = 1,5-anhydro-D-fructose + beta-D-glucose.


pollen tube development

description: The process whose specific outcome is the progression of a pollen tube over time, from its initial formation to a mature structure.


metanephric nephron tubule formation

description: The developmental process pertaining to the initial formation of a metanephric nephron tubule from unspecified parts. A metanephric nephron tubule is an epithelial tube that is part of a nephron in the metanephros.


glycolipid floppase activity

description: Catalysis of the movement of a glycolipid from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.


name: positive regulation of cell adhesion involved in single-species biofilm formation

description: Any process that activates or increases the frequency, rate or extent of cell adhesion involved in single-species biofilm formation.


name: methylglyoxal reductase (NADPH) (acetol producing) activity

description: Catalysis of the reaction: hydroxyacetone + NADP+ = H+ + methylglyoxal + NADPH.


description: Catalysis of the reaction: H2O + N-(long-chain-acyl)ethanolamine = ethanolamine + a fatty acid.


regulation of sporangiospore formation

description: Any process that modulates the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm.


name: positive regulation of smooth muscle hypertrophy

description: Any process that activates or increases the frequency, rate or extent of smooth muscle hypertrophy.


proton channel activity

description: Enables the facilitated diffusion of a hydrogen ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.


RNA polymerase III assembly

description: The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase III complex.


description: Catalysis of the reaction: (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + NAD+ = 2,3-dihydroxybenzoate + H+ + NADH.


cellular response to purvalanol A

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purvalanol A stimulus.


name: hydroxymethyl-, formyl- and related transferase activity

description: Catalysis of the transfer of a hydroxymethyl- or formyl group from one compound (donor) to another (acceptor).


chloroplast mRNA modification

description: The covalent alteration within the chloroplast of one or more nucleotides within an mRNA to produce an mRNA molecule with a sequence that differs from that coded genetically.


tongue muscle cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a tongue muscle cell.


proximal/distal pattern formation

description: The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end).


vesicle tethering

description: The initial, indirect interaction between a vesicle membrane and a membrane to which it is targeted for fusion. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to interaction between factors involved in fusion.


subsynaptic reticulum organization

description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a subsynaptic reticulum. A subsynaptic reticulum is an elaborate tubulolamellar membrane system that underlies the postsynaptic cell membrane.


description: Catalysis of the reaction: N-(6-aminohexanoyl)-6-aminohexanoate + H2O = 2 6-aminohexanoate.


detection of endogenous stimulus

description: The series of events in which an endogenous stimulus is received by a cell and converted into a molecular signal.


name: protein localization to bicellular tight junction

description: A process in which a protein is transported to, or maintained in, a location within a bicellular tight junction.


(R)-lactaldehyde dehydrogenase activity

description: Catalysis of the reaction: (R)-propane-1,2-diol + NADP = (R)-lactaldehyde + NADPH + H+.


skeletal muscle adaptation

description: Any process in which skeletal muscles change their phenotypic profiles in response to altered functional demands and a variety of signals.


name: negative regulation of fibroblast chemotaxis

description: Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast chemotaxis.


autophagosome maturation

description: Removal of PI3P and Atg8/LC3 after the closure of the phagophore and before the fusion with the endosome/lysosome (e.g. mammals and insects) or vacuole (yeast), and that very likely destabilizes other Atg proteins and thus enables their efficient dissociation and recycling.


name: positive regulation of spermidine biosynthetic process

description: Any process that activates or increases the frequency, rate or extent of spermidine biosynthetic process.


description: Catalysis of the reaction: luteolin 7-O-beta-D-glucosiduronate + UDP-alpha-D-glucuronate = H+ + luteolin 7-O-[(beta-D-glucosiduronate)-(1->2)-(beta-D-glucosiduronate)] + UDP.


name: positive regulation of dopamine metabolic process

description: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving dopamine.


anaerobic amino acid catabolic process

description: The anaerobic chemical reactions and pathways resulting in the breakdown of amino acids, yielding energy in the form of ATP.


name: positive regulation of imaginal disc-derived leg joint morphogenesis

description: Any process that activates or increases the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis.


name: positive regulation of cell adhesion involved in sprouting angiogenesis

description: Any process that activates or increases the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis.


name: positive regulation of cell proliferation involved in mesonephros development

description: Any process that activates or increases the frequency, rate or extent of cell proliferation involved in mesonephros development.


name: (gibberellin-36), 2-oxoglutarate:oxygen oxidoreductase activity

description: Catalysis of the reaction: gibberellin A36 + O2 + 2-oxoglutarate = H+ + gibberellin A4 + succinate + 2 carbon dioxide.


inositol catabolic process

description: The chemical reactions and pathways resulting in the breakdown of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms.


name: 3,3'-dibromobisphenol A reductive dehalogenase activity

description: Catalysis of the reaction: 3,3'-dibromobisphenol A + 2 H+ + 2 e- = 3-monobromobisphenol A + HBr.


name: negative regulation of melanocyte differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of melanocyte differentiation.


positive regulation of heart rate

description: Any process that activates or increases the frequency or rate of heart contraction.


name: positive regulation of galactoglucomannan catabolic process

description: Any process that activates or increases the frequency, rate or extent of galactoglucomannan catabolic process.


cellular response to chitin

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus.


name: regulation of myofibroblast cell apoptotic process

description: Any process that modulates the frequency, rate or extent of myofibroblast cell apoptotic process.


cellular response to genistein

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a genistein stimulus.


name: positive regulation of netrin-activated signaling pathway

description: Any process that activates or increases the frequency, rate or extent of netrin-activated signaling pathway.


name: 23S rRNA (adenine(1618)-N(6))-methyltransferase activity

description: Catalysis of the reaction: S-adenosyl-L-methionine + adenine(1618) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(1618) in 23S rRNA.


name: H2A-H2B histone complex chaperone activity

description: A histone chaperone that carries a H2A-H2B histone complex.


formaldehyde catabolic process

description: The chemical reactions and pathways resulting in the breakdown of formaldehyde (methanal, H2C=O), the simplest aldehyde.


cellulose synthase activity

description: Catalysis of the reaction: nucleoside-disphosphate-glucose + ((1,4)-beta-D-glucosyl)(n) = nucleoside-disphosphate + ((1,4)-beta-D-glucosyl)(n+1).


CCG codon-amino acid adaptor activity

description: A triplet codon-amino acid adaptor activity that recognizes a CCG codon.


name: protein localization to horsetail-astral microtubule array

description: A process in which a protein is transported to, or maintained in, a location within a horsetail-astral microtubule array.


vitellogenin receptor activity

description: Receiving vitellogenin, and delivering vitellogenin into the cell via endocytosis.


description: Catalysis of the hydrolysis of glucosidic link in beta-gentiobiose.


description: Catalysis of the reaction: (S)-3-(imidazol-5-yl)lactate + NADP+ = 3-(imidazol-5-yl)pyruvate + NADPH + H+.


acetoacetate decarboxylase activity

description: Catalysis of the reaction: acetoacetate + H+ = acetone + CO2.


name: L-asparagine:sodium symporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: L-asparagine(out) + Na+(out) = L-asparagine(in) + Na+(in).


strictosidine beta-glucosidase activity

description: Catalysis of the reaction: 3alpha(S)-strictosidine + H2O = D-glucose + strictosidine aglycone.


name: positive regulation by symbiont of entry into host

description: Any process that activates or increases the frequency, rate or extent to which it enters into the host organism, where the two organisms are in a symbiotic interaction.


positive regulation of chemotaxis

description: Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.


maintenance of DNA repeat elements

description: Any process involved in sustaining the fidelity and copy number of DNA repeat elements.


name: arbutin transmembrane transporter activity

description: Enables the transfer of arbutin, a glycoside found in the bearberry and related plants which has been used to treat urinary-tract diseases, from one side of a membrane to the other.


cytokinin metabolic process

description: The chemical reactions and pathways involving cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators.


description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + K+(out) + Cl-(out) = Na+(in) + K+(in) + Cl-(in).


name: cellular modified amino acid biosynthetic process

description: The chemical reactions and pathways resulting in the formation of compounds derived from amino acids, organic acids containing one or more amino substituents.


name: glomerular basement membrane development

description: The process whose specific outcome is the progression of the glomerular basement membrane over time, from its formation to the mature structure. The glomerular basement membrane is the basal laminal portion of the glomerulus which performs the actual filtration.


mesonephric capsule specification

description: The regionalization process in which the identity of the mesonephric capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.


name: RNA-(apurinic or apyrimidinic site) endonuclease activity

description: Catalysis of the hydrolysis of ester linkages immediately 5' to an apurinic/apyrimidinic (AP; also called abasic) site within a ribonucleic acid molecule by creating internal breaks, generating a single-strand break with 5'-ribose phosphate and 3'-hydroxyl ends.


name: glucose 1-dehydrogenase [NAD(P)+] activity

description: Catalysis of the reaction: beta-D-glucose + NAD(P)+ = D-glucono-1,5-lactone + NAD(P)H.


name: methylcytosine to 5-glyceryl-methylcytosine dioxygenase activity

description: Catalysis of the reaction: methylcytosine + L-ascorbate + O2 = 5-glyceryl-methylcytosine + glyoxylate + CO2.


pole plasm mRNA localization

description: Any process in which mRNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.


name: protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine

description: The modification of peptidyl-lysine to form N6-pyridoxal phosphate-L-lysine.


name: phylloquinone monooxygenase (2,3-epoxidizing) activity

description: Catalysis of the reaction: AH(2) + O2 + phylloquinone = 2,3-epoxyphylloquinone + A + H2O.


spheroidene metabolic process

description: The chemical reactions and pathways involving spheroidene.


DNA strand elongation

description: The DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand.


description: Catalysis of the reaction: cis-2-oxohept-3-ene-1,7-dioate + H2O = 2,4-dihydroxy-hept-trans-2-ene-1,7-dioate.


description: Catalysis of the reaction: apigeninidin + UDP-alpha-D-glucose = apigeninidin 5-O-glucoside + UDP + H+.


galactolipid O-acyltransferase activity

description: Catalysis of the reaction: 2 mono-beta-D-galactosyldiacylglycerol = acylmono-beta-D-galactosyl-diacylglycerol + mono-beta-D-galactosylacylglycerol.


pre-mRNA intronic binding

description: Binding to an intronic sequence of a pre-messenger RNA (pre-mRNA).


name: lipopolysaccharide glucosyltransferase I activity

description: Catalysis of the reaction: UDP-glucose + lipopolysaccharide = UDP + D-glucosyl-lipopolysaccharide.


name: palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity

description: Catalysis of the reaction: a palmitoleoyl-[acyl-carrier protein] + alpha-KDO-(2->4)-alpha-KDO-(2->6)-lipid IVA = KDO2-(palmitoleoyl)-lipid IVA + a holo-[acyl-carrier protein].


protein histidine tele-kinase activity

description: Catalysis of the reaction: ATP + protein L-histidine = ADP + protein N(tau)-phospho-L-histidine.


type B pancreatic cell differentiation

description: The process in which relatively unspecialized cells acquire specialized structural and/or functional features of a type B pancreatic cell. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin.


fructose biosynthetic process

description: The chemical reactions and pathways resulting in the formation of fructose, the ketohexose arabino-2-hexulose.


cellular response to antimycin A

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimycin A stimulus.


regulation of biological process

description: Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.


description: Catalysis of the reaction: 2-hydroxyisobutyrate + H+ = CO2 + 2-propanol.


linamarin synthase activity

description: Catalysis of the reaction: UDP-glucose + 2-hydroxy-2-methylpropanenitrile = UDP + linamarin.


name: neutral L-amino acid secondary active transmembrane transporter activity

description: Enables the transfer of a neutral L-amino acid from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.


deoxyadenosine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of deoxyadenosine, 2-deoxyribosyladenine, one of the four major nucleosides of DNA.


name: chemokine (C-C motif) ligand 17 production

description: The appearance of chemokine (C-C motif) ligand 17 (CCL17) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


intermediate mesoderm development

description: The process whose specific outcome is the progression of the intermediate mesoderm over time, from its formation to the mature structure. The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads.


name: all-trans retinoic acid 3,4-desaturase activity

description: Catalysis of the reaction: all-trans-retinoic acid + 2 H+ + O2 + 2 reduced [adrenodoxin] = all-trans-3,4-didehydro retinoic acid + 2 H2O + 2 oxidized [adrenodoxin].


peroxiredoxin activity

description: Catalysis of the reaction: [protein]-dithol + ROOH = [protein]-disulfide + H2O + ROH.


name: regulation of mesenchymal cell apoptotic process

description: Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process.


description: The series of molecular signals initiated by interleukin-13 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


sensory perception of high humidity

description: The series of events required for an organism to detect high environmental humidity, convert this detection into a molecular signal, and recognize and characterize the signal. This is a neurological process.


glucuronoxylan biosynthetic process

description: The chemical reactions and pathways resulting in the formation of glucuronoxylan, a polymer containing a beta-1,4-linked D-xylose backbone substituted with glucuronic acid residues.


name: 5-formyltetrahydrofolate transmembrane transporter activity

description: Enables the transfer of 5-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate, from one side of a membrane to the other.


name: negative regulation of zoospore encystment on host

description: Any process that stops, prevents, or reduces the frequency, rate or extent of zoospore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


description: Catalysis of the reaction: benzothiazole-2-sulfonate + H2O = 2-hydroxybenzothiazole + HSO3-.


name: envenomation resulting in modulation of platelet aggregation in another organism

description: A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change to the frequency, rate or extent of platelet aggregation in the bitten organism.


estrogen metabolic process

description: The chemical reactions and pathways involving estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants.


sterol transfer activity

description: Removes a sterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.


dendrite guidance

description: The process in which the migration of a dendrite is directed to a specific target site in response to a combination of attractive and repulsive cues.


mobile ion carrier activity

description: Small molecule produced by bacteria that carries an ion across the membrane by enclosing the ion and travelling with the ion across the membrane. It does not form a fully open pore across the membrane.


name: negative regulation of intraciliary anterograde transport

description: Any process that stops, prevents or reduces the frequency, rate or extent of intraciliary anterograde transport.


name: tRNA-type intron splice site recognition and cleavage

description: RNA processing that begins when the tertiary structure of a tRNA type intron is recognized, and ends when the endonucleolytic cleavage of the RNA at both the 5' and 3' splice sites occurs.


regulation of grooming behavior

description: Any process that modulates the frequency, rate or extent of grooming behavior.


T cell proliferation

description: The expansion of a T cell population by cell division. Follows T cell activation.


nitrite reductase [NAD(P)H] activity

description: Catalysis of the reaction: NH4+ + 3 NAD(P)+ + 2 H2O = nitrite + 3 NAD(P)H + 5 H+.


cardioblast anterior-lateral migration

description: The orderly movement of a cardioblast toward the head and laterally to form the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.


name: endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

description: Endonucleolytic cleavage within the 5'-External Transcribed Spacer (ETS) of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. Endonucleolytic cleavage within the 5'-ETS of the pre-RNA is conserved as one of the early steps of rRNA processing in all eukaryotes, but the specific position of cleavage is variable.


regulation of eating behavior

description: Any process that modulates the frequency, rate or extent of eating behavior.


name: anterior lateral line neuromast mantle cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast mantle cell. Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded.


name: negative regulation of T-helper cell differentiation

description: Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper cell differentiation.


name: apoptotic process involved in metanephric collecting duct development

description: Any apoptotic process that is involved in metanephric collecting duct development.


name: negative regulation of complement-dependent cytotoxicity

description: Any process that stops, prevents or reduces the frequency, rate or extent of complement-dependent cytotoxicity.


receptor metabolic process

description: The chemical reactions and pathways involving a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.


2-hydroxy-dATP hydrolase activity

description: Catalysis of the reaction: 2-hydroxy-dATP + H2O = 2-hydroxy-dAMP + H+ + diphosphate.


mesaconyl-CoA hydratase activity

description: Catalysis of the hydration of mesaconyl-CoA to beta-methylmalyl-CoA.


spore-bearing structure formation

description: The process of generating a spore-bearing structure. A spore-bearing structure is an anatomical structure that produces new spores.


error-free postreplication DNA repair

description: The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA via processes such as template switching, which does not remove the replication-blocking lesions but does not increase the endogenous mutation rate.


name: hydrolase activity, acting on acid carbon-carbon bonds

description: Catalysis of the hydrolysis of any acid carbon-carbon bond.


name: enterobacterial common antigen metabolic process

description: The chemical reactions and pathways involving enterobacterial common antigen, an acidic polysaccharide containing N-acetyl-D-glucosamine, N-acetyl-D-mannosaminouronic acid, and 4-acetamido-4,6-dideoxy-D-galactose. A major component of the cell wall outer membrane of Gram-negative bacteria.


regulation of transdifferentiation

description: Any process that modulates the frequency, rate or extent of transdifferentiation.


name: ornithine-acyl [acyl carrier protein] N-acyltransferase activity

description: Catalysis of the reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + L-ornithine = lyso-ornithine lipid + [acyl-carrier protein]. The enzyme, found in bacteria, catalyzes the first step in the biosynthesis of ornithine lipids.


ERK5 cascade

description: A MAPK cascade containing at least the ERK5 MAP kinase (MAPK7; also called BMK1). It starts with the activation of a MAP3K, and the consecutive activation of a MPK2K and of ERK5. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier. The ERK5 cascade is activated by stress, mitogens, and by G protein-coupled receptors, and results in cellular responses such as cell growth, cell differentiation and development.


FMN reductase (NADH) activity

description: Catalysis of the reaction: FMNH2 + NAD+ = FMN + NADH + 2 H+.


name: calcium- and calmodulin-responsive adenylate cyclase activity

description: Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate, stimulated by calcium-bound calmodulin.


omega-amidase activity

description: Catalysis of the reaction: a monoamide of a dicarboxylic acid + H2O = a dicarboxylate + NH3.


tRNA nucleoside ribose methylation

description: The process that results in the modification of the sugar of a nucleoside in tRNA at the 2'O position.


spongiotrophoblast layer development

description: The process in which the spongiotrophoblast layer of the placenta progresses from its formation to its mature state.


leg disc pattern formation

description: The process that gives rise to the patterns of cell differentiation in the leg imaginal disc.


cell cycle

description: The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.


description: Catalysis of the reaction: (2E,4Z,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioate + H2O = (2E)-2-hydroxypenta-2,4-dienoate + fumarate + H+.


name: negative regulation of calcium-independent cell-cell adhesion

description: Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-independent cell-cell adhesion.


indole glucosinolate metabolic process

description: The chemical reactions and pathways resulting in the formation of indole glucosinolates. Glucosinolates are sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan; indoles are biologically active substances based on 2,3-benzopyrrole, formed during the catabolism of tryptophan.


name: Glc2Man9GlcNAc2 oligosaccharide glucosidase activity

description: Catalysis of the reaction: Glc(2)Man(9)GlcNAc(2)-[protein] + H2O = GlcMan(9)GlcNAc(2)-[protein] + beta-D-glucopyranose.


prostanoid catabolic process

description: The chemical reactions and pathways resulting in the breakdown of prostanoids.


superoxide anion generation

description: The enzymatic generation of superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species, by a cell in response to environmental stress, thereby mediating the activation of various stress-inducible signaling pathways.


blood vessel lumen ensheathment

description: A blood vessel lumenization process that occurs by blood vessel endothelial cells delaminating and aligning along the inner surface of an existing luminal space, extending the open ended lumen, and joining to other blood vessels to form a complete blood vessel.


name: straight chain (R)-2-hydroxy fatty acyl-CoA lyase activity

description: Catalysis of the reaction: a (R)-2-hydroxy even numbered straight chain 2,3,4-saturated fatty acyl CoA = formyl-CoA + an odd numbered straight chain 2,3,4-saturated fatty aldehyde.


anti-sigma factor antagonist activity

description: The function of binding to an anti-sigma factor and stopping, preventing or reducing the rate of its activity.


name: endocardial cushion to mesenchymal transition involved in cardiac skeleton development

description: A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will give rise to the cardiac skeleton.


name: catechol-containing compound metabolic process

description: The chemical reactions and pathways involving a compound containing a pyrocatechol (1,2-benzenediol) nucleus or substituent.


description: Catalysis of the reaction: S-adenosyl-L-methionine + N-alpha,N-alpha-dimethyl-L-histidine = S-adenosyl-L-homocysteine + N-alpha,N-alpha,N-alpha-trimethyl-L-histidine.


name: dihydroceramide fatty acyl 2-hydroxylase activity

description: Catalysis of the reaction: an N-(1,2-saturated acyl)sphinganine + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = an N-[(2'R)-hydroxyacyl]sphinganine + 2 Fe(III)-[cytochrome b5] + H2O.


name: ornithine catabolic process, by decarboxylation

description: The chemical reactions and pathways resulting in the breakdown of ornithine by decarboxylation.


formation of infection structure

description: The formation of a symbiont structure that serves to infect its host organism. It includes physiological, developmental, and morphological changes of the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.


negative regulation of T cell migration

description: Any process that stops, prevents or reduces the frequency, rate or extent of T cell migration.


TDP metabolic process

description: The chemical reactions and pathways involving TDP, ribosylthymine diphosphate.


ammonia assimilation cycle

description: The pathway by which ammonia is processed and incorporated into a cell. In an energy-rich (glucose-containing), nitrogen-poor environment, glutamine synthetase and glutamate synthase form an ammonia assimilatory cycle, in which ammonia is incorporated into L-glutamate to form L-glutamine, which then combines with alpha-ketoglutarate to regenerate L-glutamate. This ATP-dependent cycle is essential for nitrogen-limited growth and for steady-state growth with some sources of nitrogen.


UDP-L-arabinose biosynthetic process

description: The chemical reactions and pathways resulting in the formation of UDP-L-arabinose, uridinediphosphoarabinose, a substance composed of arabinose in glycosidic linkage with uridine diphosphate.


name: regulation of cerebral blood circulation

description: Any process that modulates the frequency, rate or extent of cerebral blood circulation.


glial cell fate commitment

description: The process in which the developmental fate of a cell becomes restricted such that it will develop into a glial cell.


name: protein localization to cell division site involved in cell separation after cytokinesis

description: Any protein localization to cell division site that is involved in cell separation after cytokinesis.


L-arabitol catabolic process

description: The chemical reactions and pathways resulting in the breakdown of L-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group.


feminization of hermaphrodite soma

description: Promotion of female sex and sexual phenotypes in the hermaphroditic soma. An example of this is found in Caenorhabditis elegans.


name: type I interferon-mediated signaling pathway

description: The series of molecular signals initiated by type I interferon binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.


larval foraging behavior

description: The movement of a larva through a feeding substrate whilst feeding on food.


sieve element enucleation

description: The process in which nucleated precursor cells lose their nucleus as part of sieve element differentiation. The nuclear contents are released and degraded in the cytoplasm at the same time as other organelles are rearranged and the cytosol is degraded.


description: Catalysis of the reaction: aminohydroquinone + 2 e- + 2 H+ + 1/2 O2 = 1,2,4-benzenetriol + NH3.


name: symbiont-mediated perturbation of host actin cytoskeleton via filamentous actin depolymerization

description: The process in which an organism effects a change that impairs the structure or function of the host actin cytoskeleton by depolymerizing the host filamentous actin. The host is defined as the larger of the organisms involved in a symbiotic interaction.


glycine amidinotransferase activity

description: Catalysis of the reaction: L-arginine + glycine = L-ornithine + guanidinoacetate.


histone H3T45 kinase activity

description: Catalysis of the reaction: histone H3-threonine (position 45) + ATP = histone H3-phosphothreonine (position 45) + ADP. This reaction is the addition of a phosphate group to the threonine residue at position 45 of histone H3.


response to laminar fluid shear stress

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a laminar fluid shear stress stimulus. Laminar fluid flow is the force acting on an object in a system where the fluid is moving across a solid surface in parallel layers. As an example, laminar shear stress can be seen where blood flows against the luminal side of blood vessel walls.


name: complement component C4b receptor activity

description: Combining with the C4b product of the classical complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


name: mesonephric juxtaglomerulus cell differentiation

description: The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the mesonephros as it progresses from its formation to the mature state.


name: nitrate efflux transmembrane transporter activity

description: Enables the transfer of nitrate from the inside of the cell to the outside of the cell across a membrane.


response to gonadotropin

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus.


name: positive regulation of nucleobase-containing compound metabolic process

description: Any cellular process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.


limb granular cell differentiation

description: The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal granular cell.


response to hesperadin

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hesperadin stimulus.


name: plasmacytoid dendritic cell differentiation

description: The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a plasmacytoid dendritic cell.


name: tetraketide alpha-pyrone synthase activity

description: Catalyzes the reaction: a hydroxyacyl-CoA + 3 malonyl-CoA + 2 H+ = a hydroxylated tetraketide alpha-pyrone + 3 CO2 + 4 coenzyme A .


immature T cell proliferation in thymus

description: The expansion of an immature T cell population by cell division in the thymus.


(E,E)-geranyllinalool synthase activity

description: Catalysis of the reaction: all-trans-geranyl-geranyl diphosphate + H2O = (E,E)-geranyllinalool + diphosphate.


regulation of root development

description: Any process that modulates the frequency, rate or extent of root development.


prostanoid metabolic process

description: The chemical reactions and pathways involving prostanoids, any compound based on or derived from the prostanoate structure.


name: symbiont-mediated perturbation of host neurotransmitter secretion

description: A process in which a symbiont alters or subverts the regulated release of a neurotransmitter from a cell in its host organism.


response to formic acid

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a formic acid stimulus.


description: Catalysis of the reaction: anthocyanidin 3-glucoside + UDP-rhamnose = anthocyanidin 3-rutinoside + UDP.


description: Catalysis of the reaction: trans-cinnamate + NADPH + H+ + O2 = 4-hydroxycinnamate + NADP+ + H2O.


G protein-coupled UTP receptor activity

description: Combining with a nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity, activated by UTP.


inositol trisphosphate kinase activity

description: Catalysis of the reaction: inositol trisphosphate + ATP = inositol tetrakisphosphate + ADP + H+.


description: Catalysis of the reaction: 4-aminobenzoate + NADPH + H+ + O2 = 4-hydroxyaniline + NADP+ + H2O + CO2.


amylopectin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of amylopectin, the (1->4) linked alpha glucose units with alpha-(1->6) linkages.


lysosomal protein catabolic process

description: Any cellular protein catabolic process that takes place in a lysosome.


binding

description: The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.


description: Catalysis of the reaction: neoagarotetraose + H2O = 3,6-anhydro-alpha-L-galactopyranose + agarotriose.


name: regulation of acute inflammatory response to antigenic stimulus

description: Any process that modulates the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus.


protein sulfhydration

description: The modification of a protein amino acid by the addition of sulfur.


primary piRNA processing

description: The process involved in converting precursor piRNAs into non-overlapping, contiguous primary piRNAs (approximately 24-30-nt piRNAs with a preference for a 5' uridine (U) via the endonucleolytic activity of cytosolic PIWI. This may include pre-piRNA maturation of 3' ends by trimming and 2'-O-methylation.


forebrain morphogenesis

description: The process in which the anatomical structures of the forebrain are generated and organized. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions).


regulation of gastric motility

description: Any process that modulates the frequency, rate or extent of gastric motility.


nasal suture morphogenesis

description: The process in which the nasal suture is generated and organized.


mannosidase activity

description: Catalysis of the hydrolysis of mannosyl compounds, substances containing a group derived from a cyclic form of mannose or a mannose derivative.


13-series resolvin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of resolvin family 13-series, hydroxy fatty acids derived from docosapentaenoic acid.


name: lysobisphosphatidic acid metabolic process

description: The chemical reactions and pathways involving a lysobisphosphatidic acid. A lysobisphosphatidic acid is a lysophosphatidic acid having the unusual property of a phosphodiester moiety linked to positions sn-1 and sn1' of glycerol; and two additional fatty acids esterified to the glycerol head group.


protein-DNA-RNA complex assembly

description: The aggregation, arrangement and bonding together of proteins, DNA, and RNA molecules to form a protein-DNA-RNA complex.


mesoderm formation

description: The process that gives rise to the mesoderm. This process pertains to the initial formation of the structure from unspecified parts.


apical cell fate commitment

description: The process in which the developmental fate of a cell becomes restricted such that it will develop into an apical cell. The apical cell is the upper cell formed after the first division of the zygote.


endocardial cell development

description: The progression of an endocardial cell over time, from its formation to the mature cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart.


name: isoflavonoid phytoalexin metabolic process

description: The chemical reactions and pathways involving isoflavonoid phytoalexins, a group of water-soluble phenolic derivatives isomeric with flavonoids that possess antibiotic activity and are produced by plant tissues in response to infection.


observational learning

description: Learning that occurs through observing the behavior of others.


description: Catalysis of the reaction: dolichyl D-xylosyl phosphate + protein = dolichol-phosphate + D-xylosylprotein.


regulation of tRNA metabolic process

description: Any process that modulates the frequency, rate or extent of tRNA metabolic process.


secretin receptor activity

description: Combining with secretin to initiate a change in cell activity.


name: oxidoreductase activity, acting on the CH-NH group of donors

description: Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.


name: transcription elongation by RNA polymerase II

description: The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase II promoter by the addition of ribonucleotides catalyzed by RNA polymerase II.


name: regulation of chorionic trophoblast cell proliferation

description: Any process that modulates the frequency, rate or extent of chorionic trophoblast cell proliferation.


syncytium formation

description: The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane. Syncytia are normally derived from single cells that fuse or fail to complete cell division.


name: 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity

description: Catalysis of the hydroxylation of C-24 of 1-alpha,25-hydroxycholecalciferol (25-hydroxyvitamin D3; calcitriol).


name: positive regulation of cell communication by chemical coupling

description: Any process that increases the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels.


P-type manganese transporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Mn2+(in) = ADP + H+ + Mn2+(out) + phosphate.


description: Catalysis of the reaction: myricetin(1-) + S-adenosyl-L-methionine = 7-O-methylmyricetin + S-adenosyl-L-homocysteine.


description: Catalysis of the reaction: caffeoyl-CoA + putrescine = N-caffeoylputrescine + CoA + H+.


L-fucose metabolic process

description: The chemical reactions and pathways involving L-fucose, 6-deoxy-L-galactose, a sugar that occurs in fucans, a class of polysaccharides in seaweeds, especially Fucus species, and in the cell wall matrix of higher plants.


name: cerebral cortex GABAergic interneuron development

description: The process whose specific outcome is the progression of a cerebral cortex GABAergic interneuron over time, from initial commitment to its fate, to the fully functional differentiated cell.


name: protein-phosphocysteine-N-acetylglucosamine phosphotransferase system transporter activity

description: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + N-acetylglucosamine (out) = protein cysteine + N-acetylglucosamine-6-phosphate (in).


regulation of response to amylopectin

description: Any process that modulates the frequency, rate or extent of response to amylopectin.


name: histone H3R26 arginine deiminase activity

description: Catalysis of the reaction: H2O + histone H3 L-arginyl (position 26)= histone H3 L-citrullyl (position 26) + NH4+, resulting in histone H3 citrullination at position 26.


name: soyasapogenol B glucuronosyltransferase activity

description: Catalysis of the reaction: UDP-alpha-D-glucuronate + soyasapogenol B = H+ + UDP + soyasapogenol B 3-O-beta-glucuronate.


ADP deaminase activity

description: Catalysis of the reaction: ADP + H2O = IDP + NH3.


histamine metabolic process

description: The chemical reactions and pathways involving histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.


trypanothione catabolic process

description: The chemical reactions and pathways resulting in the breakdown of trypanothione (N1,N6,-bis(glutathionyl)spermidine), an essential redox intermediate in intracellular thiol redox regulation which also plays a role in protecting against oxidative stress.


name: regulation of methanophenazine biosynthetic process

description: Any process that modulates the frequency, rate or extent of methanophenazine biosynthetic process.


response to BMP

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bone morphogenetic protein (BMP) stimulus.


cellular response to food

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat.


dipeptidase activity

description: Catalysis of the hydrolysis of a dipeptide.


name: regulation of amino acid import across plasma membrane

description: Any process that modulates the frequency, rate or extent of amino acid import into a cell.


muscle tissue morphogenesis

description: The process in which the anatomical structures of muscle tissue are generated and organized. Muscle tissue consists of a set of cells that are part of an organ and carry out a contractive function.


lambda-carrageenase activity

description: Catalysis of the endohydrolysis of beta-1,4-linkages in the backbone of lambda-carrageenan, resulting in the tetrasaccharide alpha-D-Galp2,6S2-(1->3)-beta-D-Galp2S-(1->4)-alpha-D-Galp2,6S2-(1->3)-D-Galp2S.


name: regulation of retrograde trans-synaptic signaling by neuropeptide

description: Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide.


excitatory synapse assembly

description: The aggregation, arrangement and bonding together of a set of components to form an excitatory synapse.


name: regulation of activation of membrane attack complex

description: Any process that modulates the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade.


amino-acid betaine catabolic process

description: The chemical reactions and pathways resulting in the breakdown of any betaine, the N-trimethyl derivative of an amino acid.


xanthosine metabolic process

description: The chemical reactions and pathways involving xanthosine.


pyrimidine nucleotide binding

description: Binding to a pyrimidine nucleotide, a pyrimidine nucleoside esterified with (ortho)phosphate.


name: regulation of oligodendrocyte apoptotic process

description: Any process that modulates the frequency, rate or extent of oligodendrocyte apoptotic process.


hypotaurocyamine kinase activity

description: Catalysis of the reaction: ATP + hypotaurocyamine = N(omega)-phosphohypotaurocyamine + ADP + 2 H+.


name: regulation of D-amino-acid oxidase activity

description: Any process that modulates the frequency, rate or extent of D-amino-acid oxidase activity.


name: Fas-activated serine/threonine kinase activity

description: Catalysis of the reaction: ATP + Fas-activated serine/threonine protein = ADP + Fas-activated serine/threonine phosphoprotein.


name: vascular associated smooth muscle cell proliferation

description: The multiplication or reproduction of vascular smooth muscle cells, resulting in the expansion of a cell population. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.


metaphase

description: The cell cycle phase, following prophase or prometaphase in higher eukaryotes, during which chromosomes become aligned on the equatorial plate of the cell.


embryonic digestive tract development

description: The process whose specific outcome is the progression of the gut over time, from its formation to the mature structure during embryonic development. The gut is the region of the digestive tract extending from the beginning of the intestines to the anus.


glycerophospholipid flippase activity

description: Catalysis of the movement of a glycerophospholipid from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP.


name: cell wall polysaccharide catabolic process involved in abscission

description: Any cell wall polysaccharide catabolic process that is involved in abscission.


beta-amyrin 30-monooxygenase activity

description: Catalysis of the reaction: beta-amyrin + NADPH + H+ + O2 = 30-hydroxy-beta-amyrin + NADP + H2O.


fear response

description: The response of an organism to a perceived external threat.


inferior colliculus development

description: The process whose specific outcome is the progression of the inferior colliculus over time, from its formation to the mature structure. The inferior colliculus (IC) (Latin, lower hill) is the principal midbrain nucleus of the auditory pathway and receives input from several more peripheral brainstem nuclei in the auditory pathway, as well as inputs from the auditory cortex. The inferior colliculus has three subdivisions: the central nucleus (CIC), a dorsal cortex (DCIC) by which it is surrounded, and an external cortex (ICX) which is located laterally.


RISC complex binding

description: Binding to a RISC complex.


name: trans-Golgi-derived vesicle fusion with Golgi medial cisterna membrane

description: The joining of the lipid bilayer membrane around a trans-Golgi-derived vesicle to the lipid bilayer membrane around the medial-Golgi cisterna. Such vesicles include COPI-coated transport vesicles involved in retrograde transport.


name: Schwann cell proliferation involved in axon regeneration

description: The multiplication or reproduction of Schwann cells by cell division, resulting in the expansion of their population in response to an axonal lesion. The newly generated Schwann cells support subsequent axon regeneration in the peripheral nervous system.


regulation of pyruvate kinase activity

description: Any process that modulates the frequency, rate or extent of pyruvate kinase activity.


cystoblast division

description: Any of the rounds of incomplete mitosis undergone by a cystoblast to form a cyst of interconnected cells.


cardiac pacemaker cell fate commitment

description: The commitment of cells to pacemaker cell fates and their capacity to differentiate into pacemaker cells. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.


arsonoacetate metabolic process

description: The chemical reactions and pathways involving arsonoacetate, a synthetic, organic compound containing a single arsenic atom. Arsonoacetate and other arsenic containing compounds are used in agricultural applications as animal feed additives, cotton defoliants and post-emergence grass herbicides.


name: quercetin 3-gentiobioside 7-O-rhamnosyltransferase activity

description: Catalysis of the reaction: quercetin-3-gentiobioside + UDP-L-rhamnose = quercetin 3-O-gentiobioside-7-O-rhamnoside + UDP + H+.


protein-containing complex remodeling

description: The acquisition, loss, or modification of macromolecules within a complex, resulting in the alteration of an existing complex.


name: positive regulation of cell wall polysaccharide catabolic process

description: Any process that activates or increases the frequency, rate or extent of cell wall polysaccharide catabolic process.


name: positive regulation of hepatocyte differentiation

description: Any process that activates or increases the rate or extent of hepatocyte differentiation.


description: Catalysis of the reaction: 6-deoxycathasterone + O2 + a reduced electron acceptor = 6-deoxoteasterone + H2O + an oxidized electron acceptor.


keratinocyte apoptotic process

description: Any apoptotic process in a keratinocyte. A keratinocyte is an epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin.


detection of redox state

description: The series of events in which a chemical stimulus indicating redox state is received and converted into a molecular signal. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important.


interneuron migration

description: The orderly movement of an interneuron from one site to another.


name: positive regulation of granulosa cell apoptotic process

description: Any process that activates or increases the frequency, rate or extent of granulosa cell apoptotic process.


3-phenylpropionate dioxygenase activity

description: Catalysis of the reaction: 3-phenylpropionate + NADH + H+ + O2 = NAD+ + cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol.


mitochondrial DNA catabolic process

description: The chemical reactions and pathways resulting in the breakdown of mitochondrial DNA.


middle viral transcription

description: The viral transcription that takes place after early transcription in the viral life cycle, and which involves the transcription of genes required for replication.


name: negative regulation of synaptic metaplasticity

description: A process that decreases synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require.


angiotensin maturation

description: The process leading to the attainment of the full functional capacity of angiotensin by conversion of angiotensinogen into mature angiotensin in the blood.


description: The chemical reactions and pathways involving N-alpha,N-alpha,N-alpha-trimethyl-L-histidine, also known as histidine betaine or hercynine, a trimethylated derivative of histidine.


hepatic stellate cell contraction

description: The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a hepatic stellate cell.


isopentenol metabolic process

description: The chemical reactions and pathways involving isopentenol.


type IIb hypersensitivity

description: An inflammatory response resulting in cell death or dysfunction mediated by the direct binding of antibody to cellular receptors.


guanine binding

description: Binding to guanine.


ferredoxin-nitrite reductase activity

description: Catalysis of the reaction: NH3 + 2 H2O + 6 oxidized ferredoxin = nitrite + 6 reduced ferredoxin + 7 H+.


description: Catalysis of the reaction: GDP-6-deoxy-D-mannose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-mannose + NAD(P)H + H+.


name: cinnamic acid ester biosynthetic process

description: The chemical reactions and pathways resulting in the formation of ester derivatives of cinnamic acid, phenylpropenoic acid.


name: lymph gland crystal cell differentiation

description: The process in which a relatively unspecialized larval lymph gland-derived hemocyte precursor cell acquires the specialized features of a crystal cell. Crystal cells are a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph.


name: ATP-dependent protein-DNA complex displacement activity

description: An activity that displaces proteins or protein complexes from DNA, sometimes in a 'wire stripping' fashion, driven by ATP hydrolysis.


response to interleukin-9

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-9 stimulus.


D-glutamyltransferase activity

description: Catalysis of the reaction: D-glutamate + D-glutamine = gamma-D-glutamyl-D-glutamate + NH4+. Can also transfer additional glutamyl residues to a peptide, extending the polypeptide chain.


description: Catalysis of the reaction: quercetin-7-olate + UDP-D-galactose = quercetin 3-O-beta-D-galactopyranoside + UDP(3-) + H+.


cadinene metabolic process

description: The chemical reactions and pathways involving cadinene.


retroviral integrase activity

description: Catalysis of the covalent insertion of double-stranded retroviral DNA into host DNA. Proceeds by an endonucleolytic cleavage at each 3'-OH extremity of the viral genome, named 3'-processing, followed by a strand transfer reaction leading to the insertion of the processed viral DNA into the target DNA by a trans-esterification mechanism.


nicotine biosynthetic process

description: The chemical reactions and pathways resulting in the formation of nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine.


response to defenses of other organism

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the defenses of another organism.


urea carboxylase activity

description: Catalysis of the reaction: ATP + bicarbonate + urea = ADP + 2 H+ + phosphate + urea-1-carboxylate.


name: symbiont-mediated cell-to-cell migration by invasive hypha

description: The directional movement of a hyphal filament from one host cell to another. This process involves the clearance of plant-derived plasmodesmal occlusion materials, cytoskeleton based constriction of invasive hypha to traverse plasmodesmata. Septins and F-actin are reorganized into an hourglass shape at the point of maximum hyphal constriction.


execution phase of apoptosis

description: A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.


name: cellular response to topologically incorrect protein

description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure.


tryptophan 2'-dioxygenase activity

description: Catalysis of the reaction: L-tryptophan + O2 = 3-indoleglycolaldehyde + CO2 + NH3.


regulation of carbon utilization

description: Any process that modulates the frequency, rate, or extent of carbon utilization.


name: L-aspartate transmembrane transporter activity

description: Enables the transfer of L-aspartate from one side of a membrane to the other. L-aspartate is the anion derived from aspartic acid.


name: low-affinity ferric iron ion transmembrane transporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Fe2+(out) = Fe2+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.


description: Catalysis of the reaction: (+)-secoisolariciresinol + UDP-alpha-D-glucose = (+)-secoisolariciresinol monoglucoside + UDP + H+.


description: Catalysis of the reaction: 6C-glucosyl-2-hydroxynaringenin = isovitexin-7-olate + H2O.


T-helper 1 type immune response

description: An immune response which is associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis, and which is typically orchestrated by the production of particular cytokines by T-helper 1 cells, most notably interferon-gamma, IL-2, and lymphotoxin.


name: negative regulation of insulin receptor signaling pathway

description: Any process that stops, prevents, or reduces the frequency, rate or extent of insulin receptor signaling.


description: Catalysis of the reaction: 3,5-dichlorophenylcarboximide + OH- = (3,5-dichlorophenylurea)acetate.


pyridoxal phosphate catabolic process

description: The chemical reactions and pathways resulting in the breakdown of pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6.


pronephric proximal tubule development

description: The progression of the pronephric proximal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros.


name: molybdenum incorporation into iron-sulfur cluster

description: The incorporation of molybdenum into an iron-sulfur cluster.


monodictyphenone catabolic process

description: The chemical reactions and pathways resulting in the breakdown of monodictyphenone.


dephospho-CoA kinase activity

description: Catalysis of the reaction: 3'-dephospho-CoA + ATP = ADP + CoA + 2 H+.


N-terminal peptidyl-glycine acetylation

description: The acetylation of the N-terminal glycine of proteins to form the derivative N-acetylglycine.


name: dolichyl monophosphate biosynthetic process

description: The chemical reactions and pathways resulting in the formation of dolichyl diphosphate, a phosphorylated dolichol derivative.


peptidyl-proline modification

description: The modification of peptidyl-proline.


name: regulation of vascular endothelial cell proliferation

description: Any process that modulates the frequency, rate or extent of vascular endothelial cell proliferation.


description: The chemical reactions and pathways resulting in the formation of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.


trochlear nerve structural organization

description: The process that contributes to the act of creating the structural organization of the trochlear nerve. This process pertains to the physical shaping of a rudimentary structure. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.


name: regulation of entry into reproductive diapause

description: Any process that modulates the rate or extent of the dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.


name: spermidine:caffeoyl CoA N-acyltransferase activity

description: Catalysis of the transfer of a caffeoyl group to a nitrogen atom on the spermidine molecule.


description: Catalysis of the reaction: (3,5-dichlorophenylurea)acetate + OH- = 3,5-dichloroaniline + N-carboxyglycine.


name: positive regulation of apoptotic process involved in outflow tract morphogenesis

description: Any process that activates or increases the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis.


ferricrocin biosynthetic process

description: The chemical reactions and pathways resulting in the formation of ferricrocin, a cyclic hexapeptide siderophore with the structure Gly-Ser-Gly-(N5-acetyl-N5-hydroxyornithine)3.


2-chloroacrylate reductase activity

description: Catalysis of the reaction: (S)-2-chloropropanoate + NADP = 2-chloroacrylate + NADPH + H+.


tRNA N1-guanine methylation

description: The process whereby a guanine in tRNA is methylated at position N1 of the guanine.


description: Catalysis of the reaction: gamma-N-formylaminovinylacetate + H2O = gamma-aminovinylacetate + HCOOH.


DN2 thymocyte differentiation

description: The process in which a relatively unspecialized cell acquires the specialized features of a DN2 thymocyte. A DN2 thymocyte is a CD4-,CD8- thymocyte that is also CD44+,CD25-.


hindbrain tangential cell migration

description: The migration of a cell in the hindbrain in which cells move orthogonal to the direction of radial migration.


name: positive regulation of mitotic cell cycle

description: Any process that activates or increases the rate or extent of progression through the mitotic cell cycle.


dihydropterin deaminase activity

description: Catalysis of the reaction: 7,8-dihydropterin + H2O = 7,8-dihydrolumazine + NH3.


renal system vasculature morphogenesis

description: The process in which the renal system vasculature is generated and organized. Morphogenesis pertains to the creation of form.


UFM1 conjugating enzyme activity

description: Isoenergetic transfer of UFM1 from one protein to another via the reaction X-UFM1 + Y = Y-UFM1 + X, where both the X-UFM1 and Y-UFM1 linkages are thioester bonds between the C-terminal amino acid of UFM1 and a sulfhydryl side group of a cysteine residue.


response to cesium ion

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cesium stimulus.


name: positive regulation of single-species biofilm formation in or on host organism

description: Any process that activates or increases the frequency, rate or extent of single-species biofilm formation in or on host organism.


name: negative regulation of mesenchymal cell proliferation involved in ureter development

description: Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.


cytidine deaminase activity

description: Catalysis of the reaction: cytidine + H+ + H2O = uridine + NH4 and deoxycytidine + H+ + H2O = deoxyuridine + NH4+.


protein localization to motile cilium

description: A process in which a protein is transported to, or maintained in, a location within a motile cilium.


name: monocyte activation involved in immune response

description: The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.


name: regulation of metanephric S-shaped body morphogenesis

description: Any process that modulates the frequency, rate or extent of metanephric S-shaped body morphogenesis.


UDP biosynthetic process

description: The chemical reactions and pathways resulting in the formation of UDP, uridine (5'-)diphosphate.


regulation of small intestinal transit

description: Any process that modulates the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine.


ABC-type nitrate transporter activity

description: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + nitrate(out) = ADP + phosphate + nitrate(in).


endoplasmic reticulum disassembly

description: The disaggregation of an endoplasmic reticulum into its constituent components.


description: The series of molecular signals initiated by interleukin-3 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


L-arabinonate dehydratase activity

description: Catalysis of the reaction: L-arabinonate = 2-dehydro-3-deoxy-L-arabinonate + H2O.


2-nitropropane metabolic process

description: The chemical reactions and pathways involving 2-nitropropane, a clear, colorless liquid with a mild, fruity odor. 2-nitropropane is used principally as a solvent and chemical intermediate. As a solvent, it is used in inks, paints, adhesives, varnishes, polymers, and synthetic materials. It is a feedstock for the manufacture of 2-nitro-2-methyl-1-propanol and 2-amino-2-methyl-1-propanol.


name: substrate-bound cell migration, adhesion receptor recycling

description: The directed movement of accumulated adhesion components such as integrins from the rear of a migrating cell toward the cell front, where they are available to form new protrusions and adhesions.


name: aryl-alcohol dehydrogenase (NADP+) activity

description: Catalysis of the reaction: an aromatic alcohol + NADP+ = an aromatic aldehyde + NADPH.


name: antimonite secondary active transmembrane transporter activity

description: Enables the transfer of antimonite from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.


name: classical arabinogalactan protein metabolic process

description: The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein, which is composed of a group of core protein containing Hyp, Ala, Ser, Thr and Gly as the major amino acid constituents, and the C-terminus is GPI anchored.


protein localization to cell wall

description: The process of directing proteins towards the cell-wall.


lipoprotein modification

description: The chemical reactions and pathways resulting in the covalent alteration of one or more amino acid or lipid residues occurring in a lipoprotein, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.


insulin processing

description: The formation of mature insulin by proteolysis of the precursor preproinsulin. The signal sequence is first cleaved from preproinsulin to form proinsulin; proinsulin is then cleaved to release the C peptide, leaving the A and B chains of mature insulin linked by disulfide bridges.


name: regulation of embryonic camera-type eye development

description: Any process that modulates the frequency, rate or extent of embryonic camera-type eye development.


description: Catalysis of the reaction: 13-hydroxylupanine + 2-methylcrotonoyl-CoA = 13-(2-methylcrotonoyloxy)lupanine + CoA.


name: hydrogen peroxide-mediated programmed cell death

description: Programmed cell death induced by hydrogen peroxide. Programmed cell death is the cell death resulting from activation of endogenous cellular processes.


protein succinylation

description: The modification of a protein by the addition of a succinyl group (CO-CH2-CH2-CO) to an amino acid residue.


name: programmed cell death in response to retinoic acid

description: Cell death resulting from activation of endogenous cellular processes and occurring as a result of a retinoic acid.


auditory receptor cell development

description: The process whose specific outcome is the progression of an auditory receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.


name: positive regulation of filamentous growth

description: Any process that increases the frequency, rate or extent of the process in which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.


lactam metabolic process

description: The chemical reactions and pathways involving lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.


name: histone H4K20me methyltransferase activity

description: Catalysis of the reaction: N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = H+ + N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine. This reaction is the addition of a methyl group to the monomethlyated lysine residue at position 20 of histone H4, producing H4K20me2.


name: negative regulation of dopamine metabolic process

description: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving dopamine.


transketolase or transaldolase activity

description: Catalysis of the transfer of an aldehyde or ketonic group from one compound (donor) to another (acceptor).


peptidyl-serine sulfation

description: The sulfation of peptidyl-serine to form peptidyl-O-sulfo-L-serine.


CD4 biosynthetic process

description: The chemical reactions and pathways resulting in the formation of CD4, a CD marker that occurs on T-helper cells and is involved in MHC class II restricted interactions.


name: peregrinol diphosphate synthase activity

description: Catalysis of the reaction:peregrinol diphosphate = all-trans-geranylgeranyl diphosphate + H2O.


name: hindbrain-spinal cord boundary formation

description: The process whose specific outcome is the formation of the hindbrain-spinal cord boundary.


description: Catalysis of the reaction: acetyl-CoA + an aralkylamine = CoA + an N-acetylaralkylamine.


name: negative regulation of DNA topoisomerase (ATP-hydrolyzing) activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity.


name: metanephric intraglomerular mesangial cell proliferation

description: The multiplication or reproduction of intraglomerular glomerular mesangium cells in the metanephros by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis.


chylomicron assembly

description: The non-covalent aggregation and arrangement of proteins and lipids in the intestine to form a chylomicron.


vagus nerve formation

description: The process that gives rise to the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.


name: vascular associated smooth muscle cell fate commitment

description: The commitment of cells to a vascular smooth muscle cell fate and their capacity to differentiate into vascular smooth muscle cells. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.


name: branching involved in lymph vessel morphogenesis

description: The process of the coordinated growth and sprouting of lymph vessels giving rise to the organized lymphatic system.


name: regulation of mature B cell apoptotic process

description: Any process that modulates the frequency, rate, or extent of mature B cell apoptotic process.


glyoxal biosynthetic process

description: The chemical reactions and pathways resulting in the formation of glyoxal.


cyanophycin synthetase activity

description: Catalysis of the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).


name: negative regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity

description: Any process that stops, prevents or reduces the frequency, rate or extent of CDP-diacylglycerol-serine O-phosphatidyltransferase activity.


neuron cellular homeostasis

description: The cellular homeostatic process that preserves a neuron in a stable, differentiated functional and structural state.


name: regulation of chitin-based cuticle tanning

description: Any process that modulates the frequency, rate or extent of chitin-based cuticular tanning.


trans-synaptic signaling

description: Cell-cell signaling in either direction across the synaptic cleft.


name: positive regulation of backward locomotion

description: Any process that activates or increases the frequency, rate or extent of backward locomotion.


premeiotic DNA replication DNA ligation

description: Any DNA ligation involved in meiotic cell cycle DNA replication.


substantia nigra development

description: The progression of the substantia nigra over time from its initial formation until its mature state. The substantia nigra is the layer of gray substance that separates the posterior parts of the cerebral peduncles (tegmentum mesencephali) from the anterior parts; it normally includes a posterior compact part with many pigmented cells (pars compacta) and an anterior reticular part whose cells contain little pigment (pars reticularis).


pinene synthase activity

description: Catalysis of the reaction: geranyl diphosphate = pinene + diphosphate. This reaction can produce both alpha-pinene and beta-pinene.


histone H4K48 deacetylase activity

description: Catalysis of the reaction: histone H4 N6-acetyl-L-lysine (position 12) + H2O = histone H4 L-lysine (position 48) + acetate. This reaction represents the removal of an acetyl group from lysine at position 48 of the histone H4 protein.


description: Catalysis of the reaction: 4alpha-carboxy-5alpha-cholesta-7,24-dien-3beta-ol + NAD(1-) = 5alpha-cholesta-7,24-dien-3-one + NADH(2-) + carbon dioxide.


name: symbiont-mediated perturbation of host gene expression

description: A process in which a symbiont alters or subverts the normal execution of host gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. The host is defined as the larger of the organisms involved in a symbiotic interaction.


description: Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UDP + dolichyl N-acetyl-alpha-D-glucosaminyl phosphate.


name: sorbose transmembrane transporter activity

description: Enables the transfer of sorbose from one side of a membrane to the other. Sorbose is the ketohexose xylo-2-hexulose; L-sorbose is formed by bacterial oxidation of sorbitol. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid.


methylglyoxal biosynthetic process

description: The chemical reactions and pathways resulting in the formation of methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid.


intron homing

description: Lateral transfer of an intron to a homologous allele that lacks the intron, mediated by a site-specific endonuclease encoded within the mobile intron.


name: dorsal motor nucleus of vagus nerve maturation

description: A developmental process, independent of morphogenetic (shape) change, that is required for the dorsal motor nucleus of the vagus nerve to attain its fully functional state.


T-helper 2 cell lineage commitment

description: The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 2 cell, a CD4-positive, alpha-beta T cell specialized to promote immunological processes often associated with resistance to extracellular organisms such as helminths, enhanced production of particular antibody isotypes, and pathological conditions such as allergy.


name: positive regulation of outer hair cell apoptotic process

description: Any process that activates or increases the frequency, rate or extent of outer hair cell apoptotic process.


name: plant-type cell wall cellulose biosynthetic process

description: The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, as part of the organization and biogenesis of the cell wall.


name: negative regulation of cell adhesion mediated by integrin

description: Any process that stops, prevents, or reduces the frequency, rate, or extent of cell adhesion mediated by integrin.


name: regulation of copper ion transmembrane transport

description: Any process that modulates the frequency, rate or extent of copper ion transmembrane transport.


name: negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway

description: Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase C-activating G protein-coupled receptor signaling pathway.


name: positive regulation of nuclear migration during mitotic telophase

description: Any process that activates or increases the frequency, rate or extent of nuclear migration during mitotic telophase.


name: mannitol 2-dehydrogenase (NADP+) activity

description: Catalysis of the reaction: D-mannitol + NADP+ = D-fructose + H+ + NADPH.


adenyl nucleotide binding

description: Binding to an adenyl nucleotide, an adenosine esterified with (ortho)phosphate.


name: positive regulation of amine metabolic process

description: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amines.


name: iron ion transmembrane transporter activity

description: Enables the transfer of iron (Fe) ions from one side of a membrane to the other.


name: regulation of Notch signaling pathway involved in somitogenesis

description: Any process that modulates the frequency, rate or extent of Notch signaling pathway involved in somitogenesis.


callose localization

description: Any process in which callose is transported to, and/or maintained in, a specific location. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.


response to abiotic stimulus

description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (not derived from living organisms) stimulus.


name: trans-synaptic signaling by soluble gas, modulating synaptic transmission

description: Cell-cell signaling between presynapse and postsynapse, via the release and reception of gaseous molecules, that modulates the synaptic transmission properties of the synapse.


pons maturation

description: A developmental process, independent of morphogenetic (shape) change, that is required for the pons to attain its fully functional state. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.


name: positive regulation of juvenile hormone secretion

description: Any process that activates or increases the frequency, rate or extent of the regulated release of juvenile hormone.


name: mammary gland branching involved in thelarche

description: The process in which the branching structure of the mammary gland duct is generated and organized during the period of sexual maturity in mammals. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.


hatching

description: The emergence of an immature organism from a protective structure.


description: Catalysis of the hydrolysis of P(1),P(4)-bis(5'-nucleosyl)tetraphosphate into two nucleotides.


name: positive regulation of purine nucleobase metabolic process

description: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving purine bases.


N-terminal peptidyl-alanine methylation

description: The methylation of the N-terminal alanine of proteins.


ceramide glucosyltransferase activity

description: Catalysis of the reaction: UDP-glucose + N-acylsphingosine = UDP + D-glucosyl-N-acylsphingosine.


name: proximal convoluted tubule segment 2 development

description: The process whose specific outcome is the progression of the S2 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S2 portion of the tubule is involved in reabsorption of water and sodium chloride.


name: symbiont-mediated activation of host programmed cell death

description: A process in which a symbiont gene product activates host programmed cell death, leading to an increase in the frequency, rate or extent of programmed cell death in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.


name: reduced coenzyme F420 dehydrogenase activity

description: Catalysis of the reaction: methanophenazine + reduced coenzyme F420 = dihydromethanophenazine + coenzyme F420.


behavior

description: The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity.


mercury ion binding

description: Binding to a mercury ion (Hg2+).


name: negative regulation of endothelial cell migration

description: Any process that decreases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.


name: regulation of interleukin-1-mediated signaling pathway

description: Any process that modulates the frequency, rate or extent of interleukin-1-mediated signaling pathway.


name: detection of carbon dioxide by vasomotor center

description: The process by a carbon dioxide stimulus is received and converted to a molecular signal by the vasomotor center of the central nervous system.


description: Catalysis of the reaction: S-adenosyl-L-methionine + trichlorophenol = S-adenosyl-L-homocysteine + trichloroanisole.


2-iminopropanoate deaminase activity

description: Catalysis of the reaction: 2-iminopropanoate + H2O = NH4(+) + pyruvate.


description: Catalysis of the reaction: phosphatidylglycerol + phosphatidylethanolamine = cardiolipin + ethanolamine.