{
    "source_type": "primary",
    "edges": [
        {
            "subject_category": "biolink:SmallMolecule",
            "object_category": "biolink:ChemicalEntity",
            "predicate": "biolink:subclass_of",
            "subject_id": "CHEBI:32374",
            "object_id": "CHEBI:33285"
        },
        {
            "subject_category": "biolink:SmallMolecule",
            "object_category": "biolink:Gene",
            "predicate": "biolink:directly_physically_interacts_with",
            "subject_id": "GTOPDB:12652",
            "object_id": "NCBIGene:961"
        },
        {
            "subject_category": "biolink:SmallMolecule",
            "object_category": "biolink:Gene",
            "predicate": "biolink:affects",
            "subject_id": "UNII:JKP2Z098S2",
            "object_id": "NCBIGene:5144",
            "qualifiers": [
                {
                    "qualifier_type_id": "biolink:object_aspect_qualifier",
                    "qualifier_value": "activity"
                },
                {
                    "qualifier_type_id": "biolink:object_direction_qualifier",
                    "qualifier_value": "decreased"
                },
                {
                    "qualifier_type_id": "biolink:qualified_predicate",
                    "qualifier_value": "biolink:causes"
                }
            ]
        },
        {
            "subject_category": "biolink:SmallMolecule",
            "object_category": "biolink:Gene",
            "predicate": "biolink:gene_product_of",
            "subject_id": "GTOPDB:756",
            "object_id": "NCBIGene:6348"
        },
        {
            "subject_category": "biolink:SmallMolecule",
            "object_category": "biolink:SmallMolecule",
            "predicate": "biolink:has_part",
            "subject_id": "GTOPDB:2000",
            "object_id": "GTOPDB:3751"
        },
        {
            "subject_category": "biolink:SmallMolecule",
            "object_category": "biolink:SmallMolecule",
            "predicate": "biolink:subclass_of",
            "subject_id": "CHEBI:48935",
            "object_id": "CHEBI:48844"
        },
        {
            "subject_category": "biolink:SmallMolecule",
            "object_category": "biolink:MolecularMixture",
            "predicate": "biolink:subclass_of",
            "subject_id": "CHEBI:4514",
            "object_id": "CHEBI:32952"
        },
        {
            "subject_category": "biolink:SmallMolecule",
            "object_category": "biolink:ChemicalMixture",
            "predicate": "biolink:subclass_of",
            "subject_id": "CHEBI:82644",
            "object_id": "CHEBI:60004"
        },
        {
            "subject_category": "biolink:ChemicalEntity",
            "object_category": "biolink:ChemicalEntity",
            "predicate": "biolink:subclass_of",
            "subject_id": "CHEBI:70726",
            "object_id": "CHEBI:33675"
        },
        {
            "subject_category": "biolink:ChemicalEntity",
            "object_category": "biolink:Gene",
            "predicate": "biolink:directly_physically_interacts_with",
            "subject_id": "UNII:7NL2E3F6K3",
            "object_id": "NCBIGene:2159"
        },
        {
            "subject_category": "biolink:ChemicalEntity",
            "object_category": "biolink:Gene",
            "predicate": "biolink:affects",
            "subject_id": "CHEBI:16684",
            "object_id": "NCBIGene:1128",
            "qualifiers": [
                {
                    "qualifier_type_id": "biolink:object_aspect_qualifier",
                    "qualifier_value": "activity"
                },
                {
                    "qualifier_type_id": "biolink:object_direction_qualifier",
                    "qualifier_value": "decreased"
                },
                {
                    "qualifier_type_id": "biolink:qualified_predicate",
                    "qualifier_value": "biolink:causes"
                }
            ]
        },
        {
            "subject_category": "biolink:ChemicalEntity",
            "object_category": "biolink:Gene",
            "predicate": "biolink:gene_product_of",
            "subject_id": "CHEBI:80343",
            "object_id": "NCBIGene:3479"
        },
        {
            "subject_category": "biolink:ChemicalEntity",
            "object_category": "biolink:SmallMolecule",
            "predicate": "biolink:subclass_of",
            "subject_id": "CHEBI:86411",
            "object_id": "CHEBI:47519"
        },
        {
            "subject_category": "biolink:ChemicalEntity",
            "object_category": "biolink:ChemicalMixture",
            "predicate": "biolink:subclass_of",
            "subject_id": "CHEBI:16684",
            "object_id": "CHEBI:60004"
        },
        {
            "subject_category": "biolink:ChemicalEntity",
            "object_category": "biolink:MolecularMixture",
            "predicate": "biolink:subclass_of",
            "subject_id": "CHEBI:16684",
            "object_id": "CHEBI:60911"
        },
        {
            "subject_category": "biolink:MolecularMixture",
            "object_category": "biolink:ChemicalEntity",
            "predicate": "biolink:subclass_of",
            "subject_id": "CHEBI:32076",
            "object_id": "CHEBI:36566"
        },
        {
            "subject_category": "biolink:MolecularMixture",
            "object_category": "biolink:Gene",
            "predicate": "biolink:affects",
            "subject_id": "PUBCHEM.COMPOUND:90488883",
            "object_id": "NCBIGene:5032",
            "qualifiers": [
                {
                    "qualifier_type_id": "biolink:object_aspect_qualifier",
                    "qualifier_value": "activity"
                },
                {
                    "qualifier_type_id": "biolink:object_direction_qualifier",
                    "qualifier_value": "decreased"
                },
                {
                    "qualifier_type_id": "biolink:qualified_predicate",
                    "qualifier_value": "biolink:causes"
                }
            ]
        },
        {
            "subject_category": "biolink:MolecularMixture",
            "object_category": "biolink:ChemicalMixture",
            "predicate": "biolink:subclass_of",
            "subject_id": "CHEBI:134126",
            "object_id": "CHEBI:60004"
        },
        {
            "subject_category": "biolink:MolecularMixture",
            "object_category": "biolink:SmallMolecule",
            "predicate": "biolink:subclass_of",
            "subject_id": "CHEBI:77967",
            "object_id": "CHEBI:17996"
        }
    ]
}