{ "@context": { "@vocab": "https://schema.org/", "biolink": "https://w3id.org/biolink/" }, "@type": "Dataset", "@id": "https://robokop.renci.org/graphs/Hetio/1.0.3/schema.json", "name": "A ROBOKOP Knowledge Graph based on Hetionet Schema", "description": "Schema describing the nodes, edges, and attributes in the A ROBOKOP Knowledge Graph based on Hetionet knowledge graph", "encodingFormat": "application/ld+json", "isPartOf": { "@type": "Dataset", "@id": "https://robokop.renci.org/graphs/Hetio/1.0.3/", "name": "A ROBOKOP Knowledge Graph based on Hetionet" }, "schema": { "nodes": [ { "category": [ "biolink:Gene" ], "count": 400, "id_prefixes": { "NCBIGene": 400 }, "attributes": { "name": 400, "equivalent_identifiers": 400, "description": 395, "taxon": 395, "information_content": 307 } }, { "category": [ "biolink:Gene", "biolink:Protein" ], "count": 18531, "id_prefixes": { "NCBIGene": 18531 }, "attributes": { "name": 18531, "equivalent_identifiers": 18531, "description": 18531, "taxon": 18531, "information_content": 18484 } }, { "category": [ "biolink:AnatomicalEntity" ], "count": 101, "id_prefixes": { "UBERON": 97, "UMLS": 4 }, "attributes": { "name": 101, "equivalent_identifiers": 101, "information_content": 97, "description": 97 } }, { "category": [ "biolink:Drug", "biolink:SmallMolecule" ], "count": 1182, "id_prefixes": { "CHEBI": 1157, "UNII": 18, "PUBCHEM.COMPOUND": 7 }, "attributes": { "name": 1182, "equivalent_identifiers": 1182, "information_content": 1151, "description": 926 } }, { "category": [ "biolink:Disease" ], "count": 3195, "id_prefixes": { "MONDO": 1711, "UMLS": 1433, "EFO": 48, "DOID": 3 }, "attributes": { "name": 3195, "equivalent_identifiers": 3195, "information_content": 2035, "description": 1997 } }, { "category": [ "biolink:MolecularActivity" ], "count": 2609, "id_prefixes": { "GO": 2608, "UMLS": 1 }, "attributes": { "name": 2609, "equivalent_identifiers": 2609, "information_content": 2608, "description": 2608 } }, { "category": [ "biolink:PhenotypicFeature" ], "count": 2170, "id_prefixes": { "UMLS": 1092, "HP": 877, "NCIT": 178, "EFO": 23 }, "attributes": { "name": 2170, "equivalent_identifiers": 2170, "information_content": 1072, "description": 1049 } }, { "category": [ "biolink:BiologicalProcess" ], "count": 9882, "id_prefixes": { "GO": 9857, "UMLS": 25 }, "attributes": { "name": 9882, "equivalent_identifiers": 9882, "information_content": 9857, "description": 9857 } }, { "category": [ "biolink:GrossAnatomicalStructure" ], "count": 301, "id_prefixes": { "UBERON": 301 }, "attributes": { "name": 301, "equivalent_identifiers": 301, "information_content": 301, "description": 301 } }, { "category": [ "biolink:Pathway" ], "count": 307, "id_prefixes": { "GO": 307 }, "attributes": { "name": 307, "equivalent_identifiers": 307, "information_content": 307, "description": 307 } }, { "category": [ "biolink:Drug" ], "count": 49, "id_prefixes": { "CHEBI": 37, "UNII": 7, "PUBCHEM.COMPOUND": 4, "CHEMBL.COMPOUND": 1 }, "attributes": { "name": 49, "equivalent_identifiers": 49, "information_content": 41, "description": 26 } }, { "category": [ "biolink:CellularComponent" ], "count": 1290, "id_prefixes": { "GO": 1290 }, "attributes": { "name": 1290, "equivalent_identifiers": 1290, "information_content": 1290, "description": 1290 } }, { "category": [ "biolink:SmallMolecule" ], "count": 237, "id_prefixes": { "CHEBI": 223, "UNII": 9, "PUBCHEM.COMPOUND": 4, "CHEMBL.COMPOUND": 1 }, "attributes": { "name": 237, "equivalent_identifiers": 237, "information_content": 223, "description": 111 } }, { "category": [ "biolink:Protein" ], "count": 32, "id_prefixes": { "UMLS": 32 }, "attributes": { "name": 32, "equivalent_identifiers": 32 } }, { "category": [ "biolink:MolecularMixture" ], "count": 13, "id_prefixes": { "CHEBI": 9, "UNII": 3, "PUBCHEM.COMPOUND": 1 }, "attributes": { "name": 13, "equivalent_identifiers": 13, "information_content": 9, "description": 7 } }, { "category": [ "biolink:MolecularMixture", "biolink:SmallMolecule" ], "count": 10, "id_prefixes": { "CHEBI": 9, "UNII": 1 }, "attributes": { "name": 10, "equivalent_identifiers": 10, "information_content": 10, "description": 6 } }, { "category": [ "biolink:Behavior" ], "count": 22, "id_prefixes": { "UMLS": 22 }, "attributes": { "name": 22, "equivalent_identifiers": 22 } }, { "category": [ "biolink:Procedure" ], "count": 18, "id_prefixes": { "UMLS": 18 }, "attributes": { "name": 18, "equivalent_identifiers": 18 } }, { "category": [ "biolink:Cell" ], "count": 1, "id_prefixes": { "CL": 1 }, "attributes": { "name": 1, "equivalent_identifiers": 1, "information_content": 1, "description": 1 } }, { "category": [ "biolink:InformationContentEntity" ], "count": 2, "id_prefixes": { "UMLS": 2 }, "attributes": { "name": 2, "equivalent_identifiers": 2 } }, { "category": [ "biolink:ClinicalAttribute" ], "count": 4, "id_prefixes": { "UMLS": 4 }, "attributes": { "name": 4, "equivalent_identifiers": 4 } }, { "category": [ "biolink:Phenomenon" ], "count": 3, "id_prefixes": { "UMLS": 3 }, "attributes": { "name": 3, "equivalent_identifiers": 3 } }, { "category": [ "biolink:ChemicalEntity" ], "count": 1, "id_prefixes": { "CHEBI": 1 }, "attributes": { "name": 1, "equivalent_identifiers": 1, "information_content": 1, "description": 1 } } ], "nodes_summary": { "total_count": 40360, "id_prefixes": { "NCBIGene": 18931, "GO": 14062, "UMLS": 2636, "MONDO": 1711, "CHEBI": 1436, "HP": 877, "UBERON": 398, "NCIT": 178, "EFO": 71, "UNII": 38, "PUBCHEM.COMPOUND": 16, "DOID": 3, "CHEMBL.COMPOUND": 2, "CL": 1 }, "attributes": { "name": 40360, "equivalent_identifiers": 40360, "information_content": 37794, "description": 37510, "taxon": 18926 } }, "edges": [ { "subject_category": [ "biolink:Gene" ], "predicate": "biolink:genetically_interacts_with", "object_category": [ "biolink:Gene", "biolink:Protein" ], "count": 3136, "primary_knowledge_sources": { "infores:hetionet": 3136 }, "qualifiers": {}, "attributes": { "knowledge_level": 3136, "agent_type": 3136, "original_subject": 3136, "original_object": 3136, "hetio_source": 2110, "aggregator_knowledge_source": 1026 }, "subject_id_prefixes": { "NCBIGene": 3136 }, "object_id_prefixes": { "NCBIGene": 3136 } }, { "subject_category": [ "biolink:Gene", "biolink:Protein" ], "predicate": "biolink:genetically_interacts_with", "object_category": [ "biolink:Gene", "biolink:Protein" ], "count": 140214, "primary_knowledge_sources": { "infores:hetionet": 140214 }, "qualifiers": {}, "attributes": { "knowledge_level": 140214, "agent_type": 140214, "original_subject": 140214, "original_object": 140214, "aggregator_knowledge_source": 82567, "hetio_source": 57647 }, "subject_id_prefixes": { "NCBIGene": 140214 }, "object_id_prefixes": { "NCBIGene": 140214 } }, { "subject_category": [ "biolink:Gene", "biolink:Protein" ], "predicate": "biolink:expressed_in", "object_category": [ "biolink:AnatomicalEntity" ], "count": 54432, "primary_knowledge_sources": { "infores:tissues-expression-db": 54432 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 54432, "knowledge_level": 54432, "agent_type": 54432, "original_object": 54432, "original_subject": 54432 }, "subject_id_prefixes": { "NCBIGene": 54432 }, "object_id_prefixes": { "UBERON": 54432 } }, { "subject_category": [ "biolink:Drug", "biolink:SmallMolecule" ], "predicate": "biolink:regulates", "object_category": [ "biolink:Gene", "biolink:Protein" ], "count": 36392, "primary_knowledge_sources": { "infores:lincs": 36392 }, "qualifiers": { "object_aspect_qualifier": 36392, "object_direction_qualifier": 36392, "qualified_predicate": 36392 }, "attributes": { "aggregator_knowledge_source": 36392, "knowledge_level": 36392, "agent_type": 36392, "original_subject": 36392, "original_object": 36392 }, "subject_id_prefixes": { "CHEBI": 35716, "UNII": 608, "PUBCHEM.COMPOUND": 68 }, "object_id_prefixes": { "NCBIGene": 36392 } }, { "subject_category": [ "biolink:Drug", "biolink:SmallMolecule" ], "predicate": "biolink:causes", "object_category": [ "biolink:Disease" ], "count": 62524, "primary_knowledge_sources": { "infores:sider": 62524 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 62524, "knowledge_level": 62524, "agent_type": 62524, "original_subject": 62524, "original_object": 62524 }, "subject_id_prefixes": { "CHEBI": 61468, "UNII": 748, "PUBCHEM.COMPOUND": 308 }, "object_id_prefixes": { "MONDO": 50405, "UMLS": 11220, "EFO": 887, "DOID": 12 } }, { "subject_category": [ "biolink:Gene", "biolink:Protein" ], "predicate": "biolink:catalyzes", "object_category": [ "biolink:MolecularActivity" ], "count": 81981, "primary_knowledge_sources": { "infores:hetionet": 81981 }, "qualifiers": {}, "attributes": { "knowledge_level": 81981, "agent_type": 81981, "hetio_source": 81981, "original_subject": 81981, "original_object": 81981 }, "subject_id_prefixes": { "NCBIGene": 81981 }, "object_id_prefixes": { "GO": 81981 } }, { "subject_category": [ "biolink:Drug", "biolink:SmallMolecule" ], "predicate": "biolink:causes", "object_category": [ "biolink:PhenotypicFeature" ], "count": 58710, "primary_knowledge_sources": { "infores:sider": 58710 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 58710, "knowledge_level": 58710, "agent_type": 58710, "original_subject": 58710, "original_object": 58710 }, "subject_id_prefixes": { "CHEBI": 57607, "UNII": 751, "PUBCHEM.COMPOUND": 352 }, "object_id_prefixes": { "HP": 43390, "UMLS": 10127, "NCIT": 4715, "EFO": 478 } }, { "subject_category": [ "biolink:Gene", "biolink:Protein" ], "predicate": "biolink:actively_involved_in", "object_category": [ "biolink:BiologicalProcess" ], "count": 476161, "primary_knowledge_sources": { "infores:hetionet": 476161 }, "qualifiers": {}, "attributes": { "knowledge_level": 476161, "agent_type": 476161, "hetio_source": 476161, "original_subject": 476161, "original_object": 476161 }, "subject_id_prefixes": { "NCBIGene": 476161 }, "object_id_prefixes": { "GO": 476161 } }, { "subject_category": [ "biolink:Drug", "biolink:SmallMolecule" ], "predicate": "biolink:directly_physically_interacts_with", "object_category": [ "biolink:Gene", "biolink:Protein" ], "count": 9747, "primary_knowledge_sources": { "infores:hetionet": 9747 }, "qualifiers": {}, "attributes": { "knowledge_level": 9747, "agent_type": 9747, "hetio_source": 9747, "original_subject": 9747, "original_object": 9747 }, "subject_id_prefixes": { "CHEBI": 9634, "UNII": 64, "PUBCHEM.COMPOUND": 49 }, "object_id_prefixes": { "NCBIGene": 9747 } }, { "subject_category": [ "biolink:Gene", "biolink:Protein" ], "predicate": "biolink:regulates", "object_category": [ "biolink:Gene", "biolink:Protein" ], "count": 264134, "primary_knowledge_sources": { "infores:lincs": 264134 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 264134, "knowledge_level": 264134, "agent_type": 264134, "original_subject": 264134, "original_object": 264134 }, "subject_id_prefixes": { "NCBIGene": 264134 }, "object_id_prefixes": { "NCBIGene": 264134 } }, { "subject_category": [ "biolink:Gene" ], "predicate": "biolink:actively_involved_in", "object_category": [ "biolink:BiologicalProcess" ], "count": 3925, "primary_knowledge_sources": { "infores:hetionet": 3925 }, "qualifiers": {}, "attributes": { "knowledge_level": 3925, "agent_type": 3925, "hetio_source": 3925, "original_subject": 3925, "original_object": 3925 }, "subject_id_prefixes": { "NCBIGene": 3925 }, "object_id_prefixes": { "GO": 3925 } }, { "subject_category": [ "biolink:Disease" ], "predicate": "biolink:related_to", "object_category": [ "biolink:Gene", "biolink:Protein" ], "count": 12538, "primary_knowledge_sources": { "infores:hetionet": 12538 }, "qualifiers": {}, "attributes": { "knowledge_level": 12538, "agent_type": 12538, "hetio_source": 12538, "original_subject": 12538, "original_object": 12538 }, "subject_id_prefixes": { "MONDO": 12538 }, "object_id_prefixes": { "NCBIGene": 12538 } }, { "subject_category": [ "biolink:Gene", "biolink:Protein" ], "predicate": "biolink:expressed_in", "object_category": [ "biolink:GrossAnatomicalStructure" ], "count": 100873, "primary_knowledge_sources": { "infores:tissues-expression-db": 100873 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 100873, "knowledge_level": 100873, "agent_type": 100873, "original_object": 100873, "original_subject": 100873 }, "subject_id_prefixes": { "NCBIGene": 100873 }, "object_id_prefixes": { "UBERON": 100873 } }, { "subject_category": [ "biolink:Gene", "biolink:Protein" ], "predicate": "biolink:correlated_with", "object_category": [ "biolink:Gene", "biolink:Protein" ], "count": 60412, "primary_knowledge_sources": { "infores:hetionet": 60412 }, "qualifiers": {}, "attributes": { "knowledge_level": 60412, "agent_type": 60412, "hetio_source": 60412, "original_subject": 60412, "original_object": 60412 }, "subject_id_prefixes": { "NCBIGene": 60412 }, "object_id_prefixes": { "NCBIGene": 60412 } }, { "subject_category": [ "biolink:Gene", "biolink:Protein" ], "predicate": "biolink:actively_involved_in", "object_category": [ "biolink:Pathway" ], "count": 18077, "primary_knowledge_sources": { "infores:hetionet": 18077 }, "qualifiers": {}, "attributes": { "knowledge_level": 18077, "agent_type": 18077, "hetio_source": 18077, "original_subject": 18077, "original_object": 18077 }, "subject_id_prefixes": { "NCBIGene": 18077 }, "object_id_prefixes": { "GO": 18077 } }, { "subject_category": [ "biolink:Drug" ], "predicate": "biolink:causes", "object_category": [ "biolink:Disease" ], "count": 1333, "primary_knowledge_sources": { "infores:sider": 1333 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 1333, "knowledge_level": 1333, "agent_type": 1333, "original_subject": 1333, "original_object": 1333 }, "subject_id_prefixes": { "CHEBI": 1038, "PUBCHEM.COMPOUND": 197, "UNII": 92, "CHEMBL.COMPOUND": 6 }, "object_id_prefixes": { "MONDO": 1088, "UMLS": 217, "EFO": 28 } }, { "subject_category": [ "biolink:CellularComponent" ], "predicate": "biolink:has_part", "object_category": [ "biolink:Gene", "biolink:Protein" ], "count": 68038, "primary_knowledge_sources": { "infores:hetionet": 68038 }, "qualifiers": {}, "attributes": { "knowledge_level": 68038, "agent_type": 68038, "hetio_source": 68038, "original_object": 68038, "original_subject": 68038 }, "subject_id_prefixes": { "GO": 68038 }, "object_id_prefixes": { "NCBIGene": 68038 } }, { "subject_category": [ "biolink:SmallMolecule" ], "predicate": "biolink:regulates", "object_category": [ "biolink:Gene", "biolink:Protein" ], "count": 2362, "primary_knowledge_sources": { "infores:lincs": 2362 }, "qualifiers": { "object_aspect_qualifier": 2362, "object_direction_qualifier": 2362, "qualified_predicate": 2362 }, "attributes": { "aggregator_knowledge_source": 2362, "knowledge_level": 2362, "agent_type": 2362, "original_subject": 2362, "original_object": 2362 }, "subject_id_prefixes": { "CHEBI": 2300, "UNII": 60, "CHEMBL.COMPOUND": 2 }, "object_id_prefixes": { "NCBIGene": 2362 } }, { "subject_category": [ "biolink:Disease" ], "predicate": "biolink:related_to", "object_category": [ "biolink:GrossAnatomicalStructure" ], "count": 2780, "primary_knowledge_sources": { "infores:hetionet": 2780 }, "qualifiers": {}, "attributes": { "knowledge_level": 2780, "agent_type": 2780, "hetio_source": 2780, "original_subject": 2780, "original_object": 2780 }, "subject_id_prefixes": { "MONDO": 2780 }, "object_id_prefixes": { "UBERON": 2780 } }, { "subject_category": [ "biolink:Gene", "biolink:Protein" ], "predicate": "biolink:genetically_interacts_with", "object_category": [ "biolink:Gene" ], "count": 3514, "primary_knowledge_sources": { "infores:hetionet": 3514 }, "qualifiers": {}, "attributes": { "knowledge_level": 3514, "agent_type": 3514, "original_subject": 3514, "original_object": 3514, "hetio_source": 2420, "aggregator_knowledge_source": 1094 }, "subject_id_prefixes": { "NCBIGene": 3514 }, "object_id_prefixes": { "NCBIGene": 3514 } }, { "subject_category": [ "biolink:Drug", "biolink:SmallMolecule" ], "predicate": "biolink:similar_to", "object_category": [ "biolink:SmallMolecule" ], "count": 838, "primary_knowledge_sources": { "infores:hetionet": 838 }, "qualifiers": {}, "attributes": { "knowledge_level": 838, "agent_type": 838, "hetio_source": 838, "original_subject": 838, "original_object": 838 }, "subject_id_prefixes": { "CHEBI": 831, "UNII": 4, "PUBCHEM.COMPOUND": 3 }, "object_id_prefixes": { "CHEBI": 820, "UNII": 11, "PUBCHEM.COMPOUND": 6, "CHEMBL.COMPOUND": 1 } }, { "subject_category": [ "biolink:Disease" ], "predicate": "biolink:regulates", "object_category": [ "biolink:Gene", "biolink:Protein" ], "count": 15134, "primary_knowledge_sources": { "infores:hetionet": 15134 }, "qualifiers": { "object_aspect_qualifier": 15134, "object_direction_qualifier": 15134, "qualified_predicate": 15134 }, "attributes": { "knowledge_level": 15134, "agent_type": 15134, "hetio_source": 15134, "original_subject": 15134, "original_object": 15134 }, "subject_id_prefixes": { "MONDO": 15134 }, "object_id_prefixes": { "NCBIGene": 15134 } }, { "subject_category": [ "biolink:SmallMolecule" ], "predicate": "biolink:directly_physically_interacts_with", "object_category": [ "biolink:Gene", "biolink:Protein" ], "count": 930, "primary_knowledge_sources": { "infores:hetionet": 930 }, "qualifiers": {}, "attributes": { "knowledge_level": 930, "agent_type": 930, "hetio_source": 930, "original_subject": 930, "original_object": 930 }, "subject_id_prefixes": { "CHEBI": 898, "UNII": 24, "PUBCHEM.COMPOUND": 4, "CHEMBL.COMPOUND": 4 }, "object_id_prefixes": { "NCBIGene": 930 } }, { "subject_category": [ "biolink:Protein" ], "predicate": "biolink:causes", "object_category": [ "biolink:Disease" ], "count": 1774, "primary_knowledge_sources": { "infores:sider": 1774 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 1774, "knowledge_level": 1774, "agent_type": 1774, "original_subject": 1774, "original_object": 1774 }, "subject_id_prefixes": { "UMLS": 1774 }, "object_id_prefixes": { "MONDO": 1431, "UMLS": 322, "EFO": 20, "DOID": 1 } }, { "subject_category": [ "biolink:Drug", "biolink:SmallMolecule" ], "predicate": "biolink:causes", "object_category": [ "biolink:BiologicalProcess" ], "count": 684, "primary_knowledge_sources": { "infores:sider": 684 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 684, "knowledge_level": 684, "agent_type": 684, "original_subject": 684, "original_object": 684 }, "subject_id_prefixes": { "CHEBI": 667, "UNII": 9, "PUBCHEM.COMPOUND": 8 }, "object_id_prefixes": { "UMLS": 534, "GO": 150 } }, { "subject_category": [ "biolink:MolecularMixture" ], "predicate": "biolink:causes", "object_category": [ "biolink:PhenotypicFeature" ], "count": 787, "primary_knowledge_sources": { "infores:sider": 787 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 787, "knowledge_level": 787, "agent_type": 787, "original_subject": 787, "original_object": 787 }, "subject_id_prefixes": { "CHEBI": 453, "UNII": 330, "PUBCHEM.COMPOUND": 4 }, "object_id_prefixes": { "HP": 560, "UMLS": 154, "NCIT": 69, "EFO": 4 } }, { "subject_category": [ "biolink:Drug", "biolink:SmallMolecule" ], "predicate": "biolink:treats", "object_category": [ "biolink:Disease" ], "count": 691, "primary_knowledge_sources": { "infores:hetionet": 691 }, "qualifiers": {}, "attributes": { "knowledge_level": 691, "agent_type": 691, "hetio_source": 691, "original_subject": 691, "original_object": 691 }, "subject_id_prefixes": { "CHEBI": 674, "UNII": 13, "PUBCHEM.COMPOUND": 4 }, "object_id_prefixes": { "MONDO": 691 } }, { "subject_category": [ "biolink:Gene" ], "predicate": "biolink:expressed_in", "object_category": [ "biolink:GrossAnatomicalStructure" ], "count": 1151, "primary_knowledge_sources": { "infores:tissues-expression-db": 1151 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 1151, "knowledge_level": 1151, "agent_type": 1151, "original_object": 1151, "original_subject": 1151 }, "subject_id_prefixes": { "NCBIGene": 1151 }, "object_id_prefixes": { "UBERON": 1151 } }, { "subject_category": [ "biolink:Gene", "biolink:Protein" ], "predicate": "biolink:regulates", "object_category": [ "biolink:Gene" ], "count": 594, "primary_knowledge_sources": { "infores:lincs": 594 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 594, "knowledge_level": 594, "agent_type": 594, "original_subject": 594, "original_object": 594 }, "subject_id_prefixes": { "NCBIGene": 594 }, "object_id_prefixes": { "NCBIGene": 594 } }, { "subject_category": [ "biolink:Drug", "biolink:SmallMolecule" ], "predicate": "biolink:similar_to", "object_category": [ "biolink:Drug", "biolink:SmallMolecule" ], "count": 3999, "primary_knowledge_sources": { "infores:hetionet": 3999 }, "qualifiers": {}, "attributes": { "knowledge_level": 3999, "agent_type": 3999, "hetio_source": 3999, "original_subject": 3999, "original_object": 3999 }, "subject_id_prefixes": { "CHEBI": 3951, "UNII": 27, "PUBCHEM.COMPOUND": 21 }, "object_id_prefixes": { "CHEBI": 3952, "UNII": 31, "PUBCHEM.COMPOUND": 16 } }, { "subject_category": [ "biolink:MolecularMixture" ], "predicate": "biolink:causes", "object_category": [ "biolink:Disease" ], "count": 630, "primary_knowledge_sources": { "infores:sider": 630 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 630, "knowledge_level": 630, "agent_type": 630, "original_subject": 630, "original_object": 630 }, "subject_id_prefixes": { "CHEBI": 364, "UNII": 260, "PUBCHEM.COMPOUND": 6 }, "object_id_prefixes": { "MONDO": 470, "UMLS": 142, "EFO": 18 } }, { "subject_category": [ "biolink:Drug", "biolink:SmallMolecule" ], "predicate": "biolink:directly_physically_interacts_with", "object_category": [ "biolink:Gene" ], "count": 274, "primary_knowledge_sources": { "infores:hetionet": 274 }, "qualifiers": {}, "attributes": { "knowledge_level": 274, "agent_type": 274, "hetio_source": 274, "original_subject": 274, "original_object": 274 }, "subject_id_prefixes": { "CHEBI": 272, "UNII": 2 }, "object_id_prefixes": { "NCBIGene": 274 } }, { "subject_category": [ "biolink:Gene" ], "predicate": "biolink:regulates", "object_category": [ "biolink:Gene", "biolink:Protein" ], "count": 932, "primary_knowledge_sources": { "infores:lincs": 932 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 932, "knowledge_level": 932, "agent_type": 932, "original_subject": 932, "original_object": 932 }, "subject_id_prefixes": { "NCBIGene": 932 }, "object_id_prefixes": { "NCBIGene": 932 } }, { "subject_category": [ "biolink:MolecularMixture", "biolink:SmallMolecule" ], "predicate": "biolink:causes", "object_category": [ "biolink:Disease" ], "count": 101, "primary_knowledge_sources": { "infores:sider": 101 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 101, "knowledge_level": 101, "agent_type": 101, "original_subject": 101, "original_object": 101 }, "subject_id_prefixes": { "CHEBI": 78, "UNII": 23 }, "object_id_prefixes": { "MONDO": 71, "UMLS": 26, "EFO": 4 } }, { "subject_category": [ "biolink:Protein" ], "predicate": "biolink:causes", "object_category": [ "biolink:PhenotypicFeature" ], "count": 1497, "primary_knowledge_sources": { "infores:sider": 1497 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 1497, "knowledge_level": 1497, "agent_type": 1497, "original_subject": 1497, "original_object": 1497 }, "subject_id_prefixes": { "UMLS": 1497 }, "object_id_prefixes": { "HP": 1110, "UMLS": 257, "NCIT": 114, "EFO": 16 } }, { "subject_category": [ "biolink:Disease" ], "predicate": "biolink:related_to", "object_category": [ "biolink:AnatomicalEntity" ], "count": 810, "primary_knowledge_sources": { "infores:hetionet": 810 }, "qualifiers": {}, "attributes": { "knowledge_level": 810, "agent_type": 810, "hetio_source": 810, "original_subject": 810, "original_object": 810 }, "subject_id_prefixes": { "MONDO": 810 }, "object_id_prefixes": { "UBERON": 810 } }, { "subject_category": [ "biolink:SmallMolecule" ], "predicate": "biolink:causes", "object_category": [ "biolink:PhenotypicFeature" ], "count": 1138, "primary_knowledge_sources": { "infores:sider": 1138 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 1138, "knowledge_level": 1138, "agent_type": 1138, "original_subject": 1138, "original_object": 1138 }, "subject_id_prefixes": { "CHEBI": 955, "CHEMBL.COMPOUND": 90, "UNII": 62, "PUBCHEM.COMPOUND": 31 }, "object_id_prefixes": { "HP": 826, "UMLS": 200, "NCIT": 98, "EFO": 14 } }, { "subject_category": [ "biolink:CellularComponent" ], "predicate": "biolink:has_part", "object_category": [ "biolink:Gene" ], "count": 661, "primary_knowledge_sources": { "infores:hetionet": 661 }, "qualifiers": {}, "attributes": { "knowledge_level": 661, "agent_type": 661, "hetio_source": 661, "original_object": 661, "original_subject": 661 }, "subject_id_prefixes": { "GO": 661 }, "object_id_prefixes": { "NCBIGene": 661 } }, { "subject_category": [ "biolink:SmallMolecule" ], "predicate": "biolink:causes", "object_category": [ "biolink:Disease" ], "count": 1009, "primary_knowledge_sources": { "infores:sider": 1009 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 1009, "knowledge_level": 1009, "agent_type": 1009, "original_subject": 1009, "original_object": 1009 }, "subject_id_prefixes": { "CHEBI": 903, "CHEMBL.COMPOUND": 54, "UNII": 42, "PUBCHEM.COMPOUND": 10 }, "object_id_prefixes": { "MONDO": 801, "UMLS": 195, "EFO": 12, "DOID": 1 } }, { "subject_category": [ "biolink:Gene" ], "predicate": "biolink:catalyzes", "object_category": [ "biolink:MolecularActivity" ], "count": 839, "primary_knowledge_sources": { "infores:hetionet": 839 }, "qualifiers": {}, "attributes": { "knowledge_level": 839, "agent_type": 839, "hetio_source": 839, "original_subject": 839, "original_object": 839 }, "subject_id_prefixes": { "NCBIGene": 839 }, "object_id_prefixes": { "GO": 839 } }, { "subject_category": [ "biolink:Gene" ], "predicate": "biolink:expressed_in", "object_category": [ "biolink:AnatomicalEntity" ], "count": 505, "primary_knowledge_sources": { "infores:tissues-expression-db": 505 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 505, "knowledge_level": 505, "agent_type": 505, "original_object": 505, "original_subject": 505 }, "subject_id_prefixes": { "NCBIGene": 505 }, "object_id_prefixes": { "UBERON": 505 } }, { "subject_category": [ "biolink:Drug", "biolink:SmallMolecule" ], "predicate": "biolink:similar_to", "object_category": [ "biolink:Drug" ], "count": 60, "primary_knowledge_sources": { "infores:hetionet": 60 }, "qualifiers": {}, "attributes": { "knowledge_level": 60, "agent_type": 60, "hetio_source": 60, "original_subject": 60, "original_object": 60 }, "subject_id_prefixes": { "CHEBI": 56, "PUBCHEM.COMPOUND": 4 }, "object_id_prefixes": { "CHEBI": 48, "PUBCHEM.COMPOUND": 8, "UNII": 4 } }, { "subject_category": [ "biolink:Drug" ], "predicate": "biolink:causes", "object_category": [ "biolink:PhenotypicFeature" ], "count": 1248, "primary_knowledge_sources": { "infores:sider": 1248 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 1248, "knowledge_level": 1248, "agent_type": 1248, "original_subject": 1248, "original_object": 1248 }, "subject_id_prefixes": { "CHEBI": 990, "PUBCHEM.COMPOUND": 154, "UNII": 100, "CHEMBL.COMPOUND": 4 }, "object_id_prefixes": { "HP": 927, "UMLS": 191, "NCIT": 118, "EFO": 12 } }, { "subject_category": [ "biolink:SmallMolecule" ], "predicate": "biolink:similar_to", "object_category": [ "biolink:SmallMolecule" ], "count": 233, "primary_knowledge_sources": { "infores:hetionet": 233 }, "qualifiers": {}, "attributes": { "knowledge_level": 233, "agent_type": 233, "hetio_source": 233, "original_subject": 233, "original_object": 233 }, "subject_id_prefixes": { "CHEBI": 228, "PUBCHEM.COMPOUND": 3, "UNII": 2 }, "object_id_prefixes": { "CHEBI": 231, "PUBCHEM.COMPOUND": 2 } }, { "subject_category": [ "biolink:Gene" ], "predicate": "biolink:correlated_with", "object_category": [ "biolink:Gene", "biolink:Protein" ], "count": 770, "primary_knowledge_sources": { "infores:hetionet": 770 }, "qualifiers": {}, "attributes": { "knowledge_level": 770, "agent_type": 770, "hetio_source": 770, "original_subject": 770, "original_object": 770 }, "subject_id_prefixes": { "NCBIGene": 770 }, "object_id_prefixes": { "NCBIGene": 770 } }, { "subject_category": [ "biolink:SmallMolecule" ], "predicate": "biolink:similar_to", "object_category": [ "biolink:Drug", "biolink:SmallMolecule" ], "count": 923, "primary_knowledge_sources": { "infores:hetionet": 923 }, "qualifiers": {}, "attributes": { "knowledge_level": 923, "agent_type": 923, "hetio_source": 923, "original_subject": 923, "original_object": 923 }, "subject_id_prefixes": { "CHEBI": 894, "UNII": 16, "PUBCHEM.COMPOUND": 12, "CHEMBL.COMPOUND": 1 }, "object_id_prefixes": { "CHEBI": 914, "UNII": 5, "PUBCHEM.COMPOUND": 4 } }, { "subject_category": [ "biolink:Drug", "biolink:SmallMolecule" ], "predicate": "biolink:causes", "object_category": [ "biolink:Behavior" ], "count": 433, "primary_knowledge_sources": { "infores:sider": 433 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 433, "knowledge_level": 433, "agent_type": 433, "original_subject": 433, "original_object": 433 }, "subject_id_prefixes": { "CHEBI": 431, "UNII": 1, "PUBCHEM.COMPOUND": 1 }, "object_id_prefixes": { "UMLS": 433 } }, { "subject_category": [ "biolink:Disease" ], "predicate": "biolink:similar_to", "object_category": [ "biolink:Disease" ], "count": 543, "primary_knowledge_sources": { "infores:hetionet": 543 }, "qualifiers": {}, "attributes": { "knowledge_level": 543, "agent_type": 543, "hetio_source": 543, "original_subject": 543, "original_object": 543 }, "subject_id_prefixes": { "MONDO": 543 }, "object_id_prefixes": { "MONDO": 543 } }, { "subject_category": [ "biolink:Drug", "biolink:SmallMolecule" ], "predicate": "biolink:causes", "object_category": [ "biolink:Procedure" ], "count": 501, "primary_knowledge_sources": { "infores:sider": 501 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 501, "knowledge_level": 501, "agent_type": 501, "original_subject": 501, "original_object": 501 }, "subject_id_prefixes": { "CHEBI": 493, "UNII": 6, "PUBCHEM.COMPOUND": 2 }, "object_id_prefixes": { "UMLS": 501 } }, { "subject_category": [ "biolink:Drug", "biolink:SmallMolecule" ], "predicate": "biolink:regulates", "object_category": [ "biolink:Gene" ], "count": 79, "primary_knowledge_sources": { "infores:lincs": 79 }, "qualifiers": { "object_aspect_qualifier": 79, "object_direction_qualifier": 79, "qualified_predicate": 79 }, "attributes": { "aggregator_knowledge_source": 79, "knowledge_level": 79, "agent_type": 79, "original_subject": 79, "original_object": 79 }, "subject_id_prefixes": { "CHEBI": 79 }, "object_id_prefixes": { "NCBIGene": 79 } }, { "subject_category": [ "biolink:Drug", "biolink:SmallMolecule" ], "predicate": "biolink:ameliorates_condition", "object_category": [ "biolink:Disease" ], "count": 371, "primary_knowledge_sources": { "infores:hetionet": 371 }, "qualifiers": {}, "attributes": { "knowledge_level": 371, "agent_type": 371, "hetio_source": 371, "original_subject": 371, "original_object": 371 }, "subject_id_prefixes": { "CHEBI": 366, "PUBCHEM.COMPOUND": 4, "UNII": 1 }, "object_id_prefixes": { "MONDO": 371 } }, { "subject_category": [ "biolink:Protein" ], "predicate": "biolink:treats", "object_category": [ "biolink:Disease" ], "count": 23, "primary_knowledge_sources": { "infores:hetionet": 23 }, "qualifiers": {}, "attributes": { "knowledge_level": 23, "agent_type": 23, "hetio_source": 23, "original_subject": 23, "original_object": 23 }, "subject_id_prefixes": { "UMLS": 23 }, "object_id_prefixes": { "MONDO": 23 } }, { "subject_category": [ "biolink:Gene", "biolink:Protein" ], "predicate": "biolink:correlated_with", "object_category": [ "biolink:Gene" ], "count": 434, "primary_knowledge_sources": { "infores:hetionet": 434 }, "qualifiers": {}, "attributes": { "knowledge_level": 434, "agent_type": 434, "hetio_source": 434, "original_subject": 434, "original_object": 434 }, "subject_id_prefixes": { "NCBIGene": 434 }, "object_id_prefixes": { "NCBIGene": 434 } }, { "subject_category": [ "biolink:Drug" ], "predicate": "biolink:regulates", "object_category": [ "biolink:Gene", "biolink:Protein" ], "count": 364, "primary_knowledge_sources": { "infores:lincs": 364 }, "qualifiers": { "object_aspect_qualifier": 364, "object_direction_qualifier": 364, "qualified_predicate": 364 }, "attributes": { "aggregator_knowledge_source": 364, "knowledge_level": 364, "agent_type": 364, "original_subject": 364, "original_object": 364 }, "subject_id_prefixes": { "CHEBI": 324, "PUBCHEM.COMPOUND": 35, "UNII": 5 }, "object_id_prefixes": { "NCBIGene": 364 } }, { "subject_category": [ "biolink:Disease" ], "predicate": "biolink:related_to", "object_category": [ "biolink:Gene" ], "count": 83, "primary_knowledge_sources": { "infores:hetionet": 83 }, "qualifiers": {}, "attributes": { "knowledge_level": 83, "agent_type": 83, "hetio_source": 83, "original_subject": 83, "original_object": 83 }, "subject_id_prefixes": { "MONDO": 83 }, "object_id_prefixes": { "NCBIGene": 83 } }, { "subject_category": [ "biolink:Protein" ], "predicate": "biolink:causes", "object_category": [ "biolink:AnatomicalEntity" ], "count": 4, "primary_knowledge_sources": { "infores:sider": 4 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 4, "knowledge_level": 4, "agent_type": 4, "original_subject": 4, "original_object": 4 }, "subject_id_prefixes": { "UMLS": 4 }, "object_id_prefixes": { "UMLS": 4 } }, { "subject_category": [ "biolink:MolecularMixture" ], "predicate": "biolink:causes", "object_category": [ "biolink:Procedure" ], "count": 10, "primary_knowledge_sources": { "infores:sider": 10 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 10, "knowledge_level": 10, "agent_type": 10, "original_subject": 10, "original_object": 10 }, "subject_id_prefixes": { "CHEBI": 9, "UNII": 1 }, "object_id_prefixes": { "UMLS": 10 } }, { "subject_category": [ "biolink:Drug" ], "predicate": "biolink:directly_physically_interacts_with", "object_category": [ "biolink:Gene", "biolink:Protein" ], "count": 253, "primary_knowledge_sources": { "infores:hetionet": 253 }, "qualifiers": {}, "attributes": { "knowledge_level": 253, "agent_type": 253, "hetio_source": 253, "original_subject": 253, "original_object": 253 }, "subject_id_prefixes": { "CHEBI": 174, "PUBCHEM.COMPOUND": 45, "UNII": 27, "CHEMBL.COMPOUND": 7 }, "object_id_prefixes": { "NCBIGene": 253 } }, { "subject_category": [ "biolink:Protein" ], "predicate": "biolink:regulates", "object_category": [ "biolink:Gene", "biolink:Protein" ], "count": 527, "primary_knowledge_sources": { "infores:lincs": 527 }, "qualifiers": { "object_aspect_qualifier": 527, "object_direction_qualifier": 527, "qualified_predicate": 527 }, "attributes": { "aggregator_knowledge_source": 527, "knowledge_level": 527, "agent_type": 527, "original_subject": 527, "original_object": 527 }, "subject_id_prefixes": { "UMLS": 527 }, "object_id_prefixes": { "NCBIGene": 527 } }, { "subject_category": [ "biolink:Gene" ], "predicate": "biolink:regulates", "object_category": [ "biolink:Gene" ], "count": 7, "primary_knowledge_sources": { "infores:lincs": 7 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 7, "knowledge_level": 7, "agent_type": 7, "original_subject": 7, "original_object": 7 }, "subject_id_prefixes": { "NCBIGene": 7 }, "object_id_prefixes": { "NCBIGene": 7 } }, { "subject_category": [ "biolink:Protein" ], "predicate": "biolink:directly_physically_interacts_with", "object_category": [ "biolink:Gene", "biolink:Protein" ], "count": 228, "primary_knowledge_sources": { "infores:hetionet": 228 }, "qualifiers": {}, "attributes": { "knowledge_level": 228, "agent_type": 228, "hetio_source": 228, "original_subject": 228, "original_object": 228 }, "subject_id_prefixes": { "UMLS": 228 }, "object_id_prefixes": { "NCBIGene": 228 } }, { "subject_category": [ "biolink:SmallMolecule" ], "predicate": "biolink:causes", "object_category": [ "biolink:Behavior" ], "count": 2, "primary_knowledge_sources": { "infores:sider": 2 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 2, "knowledge_level": 2, "agent_type": 2, "original_subject": 2, "original_object": 2 }, "subject_id_prefixes": { "CHEBI": 2 }, "object_id_prefixes": { "UMLS": 2 } }, { "subject_category": [ "biolink:Gene" ], "predicate": "biolink:genetically_interacts_with", "object_category": [ "biolink:Gene" ], "count": 275, "primary_knowledge_sources": { "infores:hetionet": 275 }, "qualifiers": {}, "attributes": { "knowledge_level": 275, "agent_type": 275, "original_subject": 275, "original_object": 275, "aggregator_knowledge_source": 158, "hetio_source": 117 }, "subject_id_prefixes": { "NCBIGene": 275 }, "object_id_prefixes": { "NCBIGene": 275 } }, { "subject_category": [ "biolink:Gene", "biolink:Protein" ], "predicate": "biolink:expressed_in", "object_category": [ "biolink:Cell" ], "count": 50, "primary_knowledge_sources": { "infores:tissues-expression-db": 50 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 50, "knowledge_level": 50, "agent_type": 50, "original_object": 50, "original_subject": 50 }, "subject_id_prefixes": { "NCBIGene": 50 }, "object_id_prefixes": { "CL": 50 } }, { "subject_category": [ "biolink:Drug", "biolink:SmallMolecule" ], "predicate": "biolink:causes", "object_category": [ "biolink:AnatomicalEntity" ], "count": 111, "primary_knowledge_sources": { "infores:sider": 111 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 111, "knowledge_level": 111, "agent_type": 111, "original_subject": 111, "original_object": 111 }, "subject_id_prefixes": { "CHEBI": 109, "UNII": 2 }, "object_id_prefixes": { "UMLS": 111 } }, { "subject_category": [ "biolink:Disease" ], "predicate": "biolink:regulates", "object_category": [ "biolink:Gene" ], "count": 183, "primary_knowledge_sources": { "infores:hetionet": 183 }, "qualifiers": { "object_aspect_qualifier": 183, "object_direction_qualifier": 183, "qualified_predicate": 183 }, "attributes": { "knowledge_level": 183, "agent_type": 183, "hetio_source": 183, "original_subject": 183, "original_object": 183 }, "subject_id_prefixes": { "MONDO": 183 }, "object_id_prefixes": { "NCBIGene": 183 } }, { "subject_category": [ "biolink:Drug" ], "predicate": "biolink:similar_to", "object_category": [ "biolink:Drug", "biolink:SmallMolecule" ], "count": 23, "primary_knowledge_sources": { "infores:hetionet": 23 }, "qualifiers": {}, "attributes": { "knowledge_level": 23, "agent_type": 23, "hetio_source": 23, "original_subject": 23, "original_object": 23 }, "subject_id_prefixes": { "CHEBI": 17, "PUBCHEM.COMPOUND": 5, "UNII": 1 }, "object_id_prefixes": { "CHEBI": 23 } }, { "subject_category": [ "biolink:SmallMolecule" ], "predicate": "biolink:directly_physically_interacts_with", "object_category": [ "biolink:Gene" ], "count": 14, "primary_knowledge_sources": { "infores:hetionet": 14 }, "qualifiers": {}, "attributes": { "knowledge_level": 14, "agent_type": 14, "hetio_source": 14, "original_subject": 14, "original_object": 14 }, "subject_id_prefixes": { "CHEBI": 14 }, "object_id_prefixes": { "NCBIGene": 14 } }, { "subject_category": [ "biolink:Drug" ], "predicate": "biolink:causes", "object_category": [ "biolink:BiologicalProcess" ], "count": 17, "primary_knowledge_sources": { "infores:sider": 17 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 17, "knowledge_level": 17, "agent_type": 17, "original_subject": 17, "original_object": 17 }, "subject_id_prefixes": { "CHEBI": 15, "PUBCHEM.COMPOUND": 2 }, "object_id_prefixes": { "UMLS": 11, "GO": 6 } }, { "subject_category": [ "biolink:Drug" ], "predicate": "biolink:similar_to", "object_category": [ "biolink:Drug" ], "count": 9, "primary_knowledge_sources": { "infores:hetionet": 9 }, "qualifiers": {}, "attributes": { "knowledge_level": 9, "agent_type": 9, "hetio_source": 9, "original_subject": 9, "original_object": 9 }, "subject_id_prefixes": { "CHEBI": 9 }, "object_id_prefixes": { "CHEBI": 8, "UNII": 1 } }, { "subject_category": [ "biolink:Drug" ], "predicate": "biolink:treats", "object_category": [ "biolink:Disease" ], "count": 31, "primary_knowledge_sources": { "infores:hetionet": 31 }, "qualifiers": {}, "attributes": { "knowledge_level": 31, "agent_type": 31, "hetio_source": 31, "original_subject": 31, "original_object": 31 }, "subject_id_prefixes": { "CHEBI": 25, "PUBCHEM.COMPOUND": 6 }, "object_id_prefixes": { "MONDO": 31 } }, { "subject_category": [ "biolink:MolecularMixture", "biolink:SmallMolecule" ], "predicate": "biolink:causes", "object_category": [ "biolink:PhenotypicFeature" ], "count": 125, "primary_knowledge_sources": { "infores:sider": 125 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 125, "knowledge_level": 125, "agent_type": 125, "original_subject": 125, "original_object": 125 }, "subject_id_prefixes": { "CHEBI": 103, "UNII": 22 }, "object_id_prefixes": { "HP": 93, "UMLS": 19, "NCIT": 12, "EFO": 1 } }, { "subject_category": [ "biolink:Drug", "biolink:SmallMolecule" ], "predicate": "biolink:similar_to", "object_category": [ "biolink:Protein" ], "count": 78, "primary_knowledge_sources": { "infores:hetionet": 78 }, "qualifiers": {}, "attributes": { "knowledge_level": 78, "agent_type": 78, "hetio_source": 78, "original_subject": 78, "original_object": 78 }, "subject_id_prefixes": { "CHEBI": 76, "PUBCHEM.COMPOUND": 2 }, "object_id_prefixes": { "UMLS": 78 } }, { "subject_category": [ "biolink:Drug", "biolink:SmallMolecule" ], "predicate": "biolink:causes", "object_category": [ "biolink:InformationContentEntity" ], "count": 38, "primary_knowledge_sources": { "infores:sider": 38 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 38, "knowledge_level": 38, "agent_type": 38, "original_subject": 38, "original_object": 38 }, "subject_id_prefixes": { "CHEBI": 35, "UNII": 2, "PUBCHEM.COMPOUND": 1 }, "object_id_prefixes": { "UMLS": 38 } }, { "subject_category": [ "biolink:Gene" ], "predicate": "biolink:actively_involved_in", "object_category": [ "biolink:Pathway" ], "count": 146, "primary_knowledge_sources": { "infores:hetionet": 146 }, "qualifiers": {}, "attributes": { "knowledge_level": 146, "agent_type": 146, "hetio_source": 146, "original_subject": 146, "original_object": 146 }, "subject_id_prefixes": { "NCBIGene": 146 }, "object_id_prefixes": { "GO": 146 } }, { "subject_category": [ "biolink:Protein" ], "predicate": "biolink:causes", "object_category": [ "biolink:BiologicalProcess" ], "count": 15, "primary_knowledge_sources": { "infores:sider": 15 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 15, "knowledge_level": 15, "agent_type": 15, "original_subject": 15, "original_object": 15 }, "subject_id_prefixes": { "UMLS": 15 }, "object_id_prefixes": { "UMLS": 10, "GO": 5 } }, { "subject_category": [ "biolink:MolecularMixture" ], "predicate": "biolink:directly_physically_interacts_with", "object_category": [ "biolink:Gene", "biolink:Protein" ], "count": 23, "primary_knowledge_sources": { "infores:hetionet": 23 }, "qualifiers": {}, "attributes": { "knowledge_level": 23, "agent_type": 23, "hetio_source": 23, "original_subject": 23, "original_object": 23 }, "subject_id_prefixes": { "CHEBI": 14, "UNII": 7, "PUBCHEM.COMPOUND": 2 }, "object_id_prefixes": { "NCBIGene": 23 } }, { "subject_category": [ "biolink:Disease" ], "predicate": "biolink:related_to", "object_category": [ "biolink:CellularComponent" ], "count": 9, "primary_knowledge_sources": { "infores:hetionet": 9 }, "qualifiers": {}, "attributes": { "knowledge_level": 9, "agent_type": 9, "hetio_source": 9, "original_subject": 9, "original_object": 9 }, "subject_id_prefixes": { "MONDO": 9 }, "object_id_prefixes": { "GO": 9 } }, { "subject_category": [ "biolink:SmallMolecule" ], "predicate": "biolink:treats", "object_category": [ "biolink:Disease" ], "count": 5, "primary_knowledge_sources": { "infores:hetionet": 5 }, "qualifiers": {}, "attributes": { "knowledge_level": 5, "agent_type": 5, "hetio_source": 5, "original_subject": 5, "original_object": 5 }, "subject_id_prefixes": { "CHEBI": 3, "UNII": 2 }, "object_id_prefixes": { "MONDO": 5 } }, { "subject_category": [ "biolink:MolecularMixture", "biolink:SmallMolecule" ], "predicate": "biolink:similar_to", "object_category": [ "biolink:Drug", "biolink:SmallMolecule" ], "count": 27, "primary_knowledge_sources": { "infores:hetionet": 27 }, "qualifiers": {}, "attributes": { "knowledge_level": 27, "agent_type": 27, "hetio_source": 27, "original_subject": 27, "original_object": 27 }, "subject_id_prefixes": { "CHEBI": 27 }, "object_id_prefixes": { "CHEBI": 27 } }, { "subject_category": [ "biolink:Protein" ], "predicate": "biolink:similar_to", "object_category": [ "biolink:Drug", "biolink:SmallMolecule" ], "count": 81, "primary_knowledge_sources": { "infores:hetionet": 81 }, "qualifiers": {}, "attributes": { "knowledge_level": 81, "agent_type": 81, "hetio_source": 81, "original_subject": 81, "original_object": 81 }, "subject_id_prefixes": { "UMLS": 81 }, "object_id_prefixes": { "CHEBI": 77, "PUBCHEM.COMPOUND": 3, "UNII": 1 } }, { "subject_category": [ "biolink:Protein" ], "predicate": "biolink:causes", "object_category": [ "biolink:Behavior" ], "count": 7, "primary_knowledge_sources": { "infores:sider": 7 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 7, "knowledge_level": 7, "agent_type": 7, "original_subject": 7, "original_object": 7 }, "subject_id_prefixes": { "UMLS": 7 }, "object_id_prefixes": { "UMLS": 7 } }, { "subject_category": [ "biolink:MolecularMixture", "biolink:SmallMolecule" ], "predicate": "biolink:causes", "object_category": [ "biolink:BiologicalProcess" ], "count": 5, "primary_knowledge_sources": { "infores:sider": 5 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 5, "knowledge_level": 5, "agent_type": 5, "original_subject": 5, "original_object": 5 }, "subject_id_prefixes": { "UNII": 3, "CHEBI": 2 }, "object_id_prefixes": { "UMLS": 3, "GO": 2 } }, { "subject_category": [ "biolink:MolecularMixture", "biolink:SmallMolecule" ], "predicate": "biolink:directly_physically_interacts_with", "object_category": [ "biolink:Gene", "biolink:Protein" ], "count": 53, "primary_knowledge_sources": { "infores:hetionet": 53 }, "qualifiers": {}, "attributes": { "knowledge_level": 53, "agent_type": 53, "hetio_source": 53, "original_subject": 53, "original_object": 53 }, "subject_id_prefixes": { "CHEBI": 49, "UNII": 4 }, "object_id_prefixes": { "NCBIGene": 53 } }, { "subject_category": [ "biolink:Protein" ], "predicate": "biolink:similar_to", "object_category": [ "biolink:Protein" ], "count": 27, "primary_knowledge_sources": { "infores:hetionet": 27 }, "qualifiers": {}, "attributes": { "knowledge_level": 27, "agent_type": 27, "hetio_source": 27, "original_subject": 27, "original_object": 27 }, "subject_id_prefixes": { "UMLS": 27 }, "object_id_prefixes": { "UMLS": 27 } }, { "subject_category": [ "biolink:Protein" ], "predicate": "biolink:causes", "object_category": [ "biolink:Procedure" ], "count": 12, "primary_knowledge_sources": { "infores:sider": 12 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 12, "knowledge_level": 12, "agent_type": 12, "original_subject": 12, "original_object": 12 }, "subject_id_prefixes": { "UMLS": 12 }, "object_id_prefixes": { "UMLS": 12 } }, { "subject_category": [ "biolink:SmallMolecule" ], "predicate": "biolink:similar_to", "object_category": [ "biolink:Drug" ], "count": 19, "primary_knowledge_sources": { "infores:hetionet": 19 }, "qualifiers": {}, "attributes": { "knowledge_level": 19, "agent_type": 19, "hetio_source": 19, "original_subject": 19, "original_object": 19 }, "subject_id_prefixes": { "CHEBI": 17, "UNII": 2 }, "object_id_prefixes": { "CHEBI": 18, "PUBCHEM.COMPOUND": 1 } }, { "subject_category": [ "biolink:SmallMolecule" ], "predicate": "biolink:regulates", "object_category": [ "biolink:Gene" ], "count": 7, "primary_knowledge_sources": { "infores:lincs": 7 }, "qualifiers": { "object_aspect_qualifier": 7, "object_direction_qualifier": 7, "qualified_predicate": 7 }, "attributes": { "aggregator_knowledge_source": 7, "knowledge_level": 7, "agent_type": 7, "original_subject": 7, "original_object": 7 }, "subject_id_prefixes": { "CHEBI": 7 }, "object_id_prefixes": { "NCBIGene": 7 } }, { "subject_category": [ "biolink:Drug" ], "predicate": "biolink:causes", "object_category": [ "biolink:AnatomicalEntity" ], "count": 2, "primary_knowledge_sources": { "infores:sider": 2 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 2, "knowledge_level": 2, "agent_type": 2, "original_subject": 2, "original_object": 2 }, "subject_id_prefixes": { "UNII": 1, "CHEBI": 1 }, "object_id_prefixes": { "UMLS": 2 } }, { "subject_category": [ "biolink:MolecularMixture" ], "predicate": "biolink:similar_to", "object_category": [ "biolink:Drug", "biolink:SmallMolecule" ], "count": 5, "primary_knowledge_sources": { "infores:hetionet": 5 }, "qualifiers": {}, "attributes": { "knowledge_level": 5, "agent_type": 5, "hetio_source": 5, "original_subject": 5, "original_object": 5 }, "subject_id_prefixes": { "CHEBI": 5 }, "object_id_prefixes": { "CHEBI": 4, "PUBCHEM.COMPOUND": 1 } }, { "subject_category": [ "biolink:SmallMolecule" ], "predicate": "biolink:ameliorates_condition", "object_category": [ "biolink:Disease" ], "count": 2, "primary_knowledge_sources": { "infores:hetionet": 2 }, "qualifiers": {}, "attributes": { "knowledge_level": 2, "agent_type": 2, "hetio_source": 2, "original_subject": 2, "original_object": 2 }, "subject_id_prefixes": { "CHEBI": 2 }, "object_id_prefixes": { "MONDO": 2 } }, { "subject_category": [ "biolink:Protein" ], "predicate": "biolink:ameliorates_condition", "object_category": [ "biolink:Disease" ], "count": 4, "primary_knowledge_sources": { "infores:hetionet": 4 }, "qualifiers": {}, "attributes": { "knowledge_level": 4, "agent_type": 4, "hetio_source": 4, "original_subject": 4, "original_object": 4 }, "subject_id_prefixes": { "UMLS": 4 }, "object_id_prefixes": { "MONDO": 4 } }, { "subject_category": [ "biolink:Drug", "biolink:SmallMolecule" ], "predicate": "biolink:causes", "object_category": [ "biolink:ClinicalAttribute" ], "count": 13, "primary_knowledge_sources": { "infores:sider": 13 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 13, "knowledge_level": 13, "agent_type": 13, "original_subject": 13, "original_object": 13 }, "subject_id_prefixes": { "CHEBI": 13 }, "object_id_prefixes": { "UMLS": 13 } }, { "subject_category": [ "biolink:Drug" ], "predicate": "biolink:ameliorates_condition", "object_category": [ "biolink:Disease" ], "count": 7, "primary_knowledge_sources": { "infores:hetionet": 7 }, "qualifiers": {}, "attributes": { "knowledge_level": 7, "agent_type": 7, "hetio_source": 7, "original_subject": 7, "original_object": 7 }, "subject_id_prefixes": { "CHEBI": 4, "UNII": 2, "PUBCHEM.COMPOUND": 1 }, "object_id_prefixes": { "MONDO": 7 } }, { "subject_category": [ "biolink:MolecularMixture" ], "predicate": "biolink:causes", "object_category": [ "biolink:BiologicalProcess" ], "count": 23, "primary_knowledge_sources": { "infores:sider": 23 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 23, "knowledge_level": 23, "agent_type": 23, "original_subject": 23, "original_object": 23 }, "subject_id_prefixes": { "CHEBI": 13, "UNII": 10 }, "object_id_prefixes": { "UMLS": 20, "GO": 3 } }, { "subject_category": [ "biolink:SmallMolecule" ], "predicate": "biolink:causes", "object_category": [ "biolink:BiologicalProcess" ], "count": 9, "primary_knowledge_sources": { "infores:sider": 9 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 9, "knowledge_level": 9, "agent_type": 9, "original_subject": 9, "original_object": 9 }, "subject_id_prefixes": { "CHEBI": 8, "UNII": 1 }, "object_id_prefixes": { "UMLS": 7, "GO": 2 } }, { "subject_category": [ "biolink:Drug", "biolink:SmallMolecule" ], "predicate": "biolink:causes", "object_category": [ "biolink:Phenomenon" ], "count": 10, "primary_knowledge_sources": { "infores:sider": 10 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 10, "knowledge_level": 10, "agent_type": 10, "original_subject": 10, "original_object": 10 }, "subject_id_prefixes": { "CHEBI": 10 }, "object_id_prefixes": { "UMLS": 10 } }, { "subject_category": [ "biolink:SmallMolecule" ], "predicate": "biolink:similar_to", "object_category": [ "biolink:Protein" ], "count": 17, "primary_knowledge_sources": { "infores:hetionet": 17 }, "qualifiers": {}, "attributes": { "knowledge_level": 17, "agent_type": 17, "hetio_source": 17, "original_subject": 17, "original_object": 17 }, "subject_id_prefixes": { "CHEBI": 14, "UNII": 3 }, "object_id_prefixes": { "UMLS": 17 } }, { "subject_category": [ "biolink:Drug", "biolink:SmallMolecule" ], "predicate": "biolink:similar_to", "object_category": [ "biolink:MolecularMixture", "biolink:SmallMolecule" ], "count": 13, "primary_knowledge_sources": { "infores:hetionet": 13 }, "qualifiers": {}, "attributes": { "knowledge_level": 13, "agent_type": 13, "hetio_source": 13, "original_subject": 13, "original_object": 13 }, "subject_id_prefixes": { "CHEBI": 13 }, "object_id_prefixes": { "CHEBI": 13 } }, { "subject_category": [ "biolink:Drug" ], "predicate": "biolink:similar_to", "object_category": [ "biolink:SmallMolecule" ], "count": 14, "primary_knowledge_sources": { "infores:hetionet": 14 }, "qualifiers": {}, "attributes": { "knowledge_level": 14, "agent_type": 14, "hetio_source": 14, "original_subject": 14, "original_object": 14 }, "subject_id_prefixes": { "CHEBI": 9, "PUBCHEM.COMPOUND": 5 }, "object_id_prefixes": { "CHEBI": 14 } }, { "subject_category": [ "biolink:SmallMolecule" ], "predicate": "biolink:causes", "object_category": [ "biolink:Procedure" ], "count": 7, "primary_knowledge_sources": { "infores:sider": 7 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 7, "knowledge_level": 7, "agent_type": 7, "original_subject": 7, "original_object": 7 }, "subject_id_prefixes": { "CHEBI": 7 }, "object_id_prefixes": { "UMLS": 7 } }, { "subject_category": [ "biolink:Drug", "biolink:SmallMolecule" ], "predicate": "biolink:similar_to", "object_category": [ "biolink:ChemicalEntity" ], "count": 2, "primary_knowledge_sources": { "infores:hetionet": 2 }, "qualifiers": {}, "attributes": { "knowledge_level": 2, "agent_type": 2, "hetio_source": 2, "original_subject": 2, "original_object": 2 }, "subject_id_prefixes": { "CHEBI": 1, "PUBCHEM.COMPOUND": 1 }, "object_id_prefixes": { "CHEBI": 2 } }, { "subject_category": [ "biolink:MolecularMixture", "biolink:SmallMolecule" ], "predicate": "biolink:causes", "object_category": [ "biolink:Procedure" ], "count": 2, "primary_knowledge_sources": { "infores:sider": 2 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 2, "knowledge_level": 2, "agent_type": 2, "original_subject": 2, "original_object": 2 }, "subject_id_prefixes": { "CHEBI": 2 }, "object_id_prefixes": { "UMLS": 2 } }, { "subject_category": [ "biolink:Drug" ], "predicate": "biolink:causes", "object_category": [ "biolink:Behavior" ], "count": 4, "primary_knowledge_sources": { "infores:sider": 4 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 4, "knowledge_level": 4, "agent_type": 4, "original_subject": 4, "original_object": 4 }, "subject_id_prefixes": { "CHEBI": 4 }, "object_id_prefixes": { "UMLS": 4 } }, { "subject_category": [ "biolink:Gene" ], "predicate": "biolink:expressed_in", "object_category": [ "biolink:Cell" ], "count": 2, "primary_knowledge_sources": { "infores:tissues-expression-db": 2 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 2, "knowledge_level": 2, "agent_type": 2, "original_object": 2, "original_subject": 2 }, "subject_id_prefixes": { "NCBIGene": 2 }, "object_id_prefixes": { "CL": 2 } }, { "subject_category": [ "biolink:Protein" ], "predicate": "biolink:directly_physically_interacts_with", "object_category": [ "biolink:Gene" ], "count": 7, "primary_knowledge_sources": { "infores:hetionet": 7 }, "qualifiers": {}, "attributes": { "knowledge_level": 7, "agent_type": 7, "hetio_source": 7, "original_subject": 7, "original_object": 7 }, "subject_id_prefixes": { "UMLS": 7 }, "object_id_prefixes": { "NCBIGene": 7 } }, { "subject_category": [ "biolink:Gene" ], "predicate": "biolink:correlated_with", "object_category": [ "biolink:Gene" ], "count": 5, "primary_knowledge_sources": { "infores:hetionet": 5 }, "qualifiers": {}, "attributes": { "knowledge_level": 5, "agent_type": 5, "hetio_source": 5, "original_subject": 5, "original_object": 5 }, "subject_id_prefixes": { "NCBIGene": 5 }, "object_id_prefixes": { "NCBIGene": 5 } }, { "subject_category": [ "biolink:Drug", "biolink:SmallMolecule" ], "predicate": "biolink:similar_to", "object_category": [ "biolink:MolecularMixture" ], "count": 2, "primary_knowledge_sources": { "infores:hetionet": 2 }, "qualifiers": {}, "attributes": { "knowledge_level": 2, "agent_type": 2, "hetio_source": 2, "original_subject": 2, "original_object": 2 }, "subject_id_prefixes": { "CHEBI": 2 }, "object_id_prefixes": { "CHEBI": 2 } }, { "subject_category": [ "biolink:MolecularMixture" ], "predicate": "biolink:similar_to", "object_category": [ "biolink:MolecularMixture" ], "count": 11, "primary_knowledge_sources": { "infores:hetionet": 11 }, "qualifiers": {}, "attributes": { "knowledge_level": 11, "agent_type": 11, "hetio_source": 11, "original_subject": 11, "original_object": 11 }, "subject_id_prefixes": { "CHEBI": 8, "UNII": 3 }, "object_id_prefixes": { "CHEBI": 7, "UNII": 4 } }, { "subject_category": [ "biolink:MolecularMixture", "biolink:SmallMolecule" ], "predicate": "biolink:similar_to", "object_category": [ "biolink:SmallMolecule" ], "count": 7, "primary_knowledge_sources": { "infores:hetionet": 7 }, "qualifiers": {}, "attributes": { "knowledge_level": 7, "agent_type": 7, "hetio_source": 7, "original_subject": 7, "original_object": 7 }, "subject_id_prefixes": { "CHEBI": 7 }, "object_id_prefixes": { "CHEBI": 6, "UNII": 1 } }, { "subject_category": [ "biolink:Drug" ], "predicate": "biolink:causes", "object_category": [ "biolink:Procedure" ], "count": 8, "primary_knowledge_sources": { "infores:sider": 8 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 8, "knowledge_level": 8, "agent_type": 8, "original_subject": 8, "original_object": 8 }, "subject_id_prefixes": { "CHEBI": 7, "UNII": 1 }, "object_id_prefixes": { "UMLS": 8 } }, { "subject_category": [ "biolink:MolecularMixture", "biolink:SmallMolecule" ], "predicate": "biolink:regulates", "object_category": [ "biolink:Gene", "biolink:Protein" ], "count": 3, "primary_knowledge_sources": { "infores:lincs": 3 }, "qualifiers": { "object_aspect_qualifier": 3, "object_direction_qualifier": 3, "qualified_predicate": 3 }, "attributes": { "aggregator_knowledge_source": 3, "knowledge_level": 3, "agent_type": 3, "original_subject": 3, "original_object": 3 }, "subject_id_prefixes": { "CHEBI": 3 }, "object_id_prefixes": { "NCBIGene": 3 } }, { "subject_category": [ "biolink:Disease" ], "predicate": "biolink:related_to", "object_category": [ "biolink:Cell" ], "count": 3, "primary_knowledge_sources": { "infores:hetionet": 3 }, "qualifiers": {}, "attributes": { "knowledge_level": 3, "agent_type": 3, "hetio_source": 3, "original_subject": 3, "original_object": 3 }, "subject_id_prefixes": { "MONDO": 3 }, "object_id_prefixes": { "CL": 3 } }, { "subject_category": [ "biolink:SmallMolecule" ], "predicate": "biolink:causes", "object_category": [ "biolink:AnatomicalEntity" ], "count": 1, "primary_knowledge_sources": { "infores:sider": 1 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 1, "knowledge_level": 1, "agent_type": 1, "original_subject": 1, "original_object": 1 }, "subject_id_prefixes": { "CHEBI": 1 }, "object_id_prefixes": { "UMLS": 1 } }, { "subject_category": [ "biolink:Drug", "biolink:SmallMolecule" ], "predicate": "biolink:causes", "object_category": [ "biolink:MolecularActivity" ], "count": 3, "primary_knowledge_sources": { "infores:sider": 3 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 3, "knowledge_level": 3, "agent_type": 3, "original_subject": 3, "original_object": 3 }, "subject_id_prefixes": { "CHEBI": 3 }, "object_id_prefixes": { "UMLS": 3 } }, { "subject_category": [ "biolink:Protein" ], "predicate": "biolink:similar_to", "object_category": [ "biolink:MolecularMixture", "biolink:SmallMolecule" ], "count": 3, "primary_knowledge_sources": { "infores:hetionet": 3 }, "qualifiers": {}, "attributes": { "knowledge_level": 3, "agent_type": 3, "hetio_source": 3, "original_subject": 3, "original_object": 3 }, "subject_id_prefixes": { "UMLS": 3 }, "object_id_prefixes": { "CHEBI": 3 } }, { "subject_category": [ "biolink:Drug" ], "predicate": "biolink:regulates", "object_category": [ "biolink:Gene" ], "count": 1, "primary_knowledge_sources": { "infores:lincs": 1 }, "qualifiers": { "object_aspect_qualifier": 1, "object_direction_qualifier": 1, "qualified_predicate": 1 }, "attributes": { "aggregator_knowledge_source": 1, "knowledge_level": 1, "agent_type": 1, "original_subject": 1, "original_object": 1 }, "subject_id_prefixes": { "CHEBI": 1 }, "object_id_prefixes": { "NCBIGene": 1 } }, { "subject_category": [ "biolink:ChemicalEntity" ], "predicate": "biolink:directly_physically_interacts_with", "object_category": [ "biolink:Gene", "biolink:Protein" ], "count": 1, "primary_knowledge_sources": { "infores:hetionet": 1 }, "qualifiers": {}, "attributes": { "knowledge_level": 1, "agent_type": 1, "hetio_source": 1, "original_subject": 1, "original_object": 1 }, "subject_id_prefixes": { "CHEBI": 1 }, "object_id_prefixes": { "NCBIGene": 1 } }, { "subject_category": [ "biolink:MolecularMixture", "biolink:SmallMolecule" ], "predicate": "biolink:ameliorates_condition", "object_category": [ "biolink:Disease" ], "count": 1, "primary_knowledge_sources": { "infores:hetionet": 1 }, "qualifiers": {}, "attributes": { "knowledge_level": 1, "agent_type": 1, "hetio_source": 1, "original_subject": 1, "original_object": 1 }, "subject_id_prefixes": { "CHEBI": 1 }, "object_id_prefixes": { "MONDO": 1 } }, { "subject_category": [ "biolink:MolecularMixture", "biolink:SmallMolecule" ], "predicate": "biolink:similar_to", "object_category": [ "biolink:Protein" ], "count": 3, "primary_knowledge_sources": { "infores:hetionet": 3 }, "qualifiers": {}, "attributes": { "knowledge_level": 3, "agent_type": 3, "hetio_source": 3, "original_subject": 3, "original_object": 3 }, "subject_id_prefixes": { "CHEBI": 3 }, "object_id_prefixes": { "UMLS": 3 } }, { "subject_category": [ "biolink:ChemicalEntity" ], "predicate": "biolink:similar_to", "object_category": [ "biolink:SmallMolecule" ], "count": 1, "primary_knowledge_sources": { "infores:hetionet": 1 }, "qualifiers": {}, "attributes": { "knowledge_level": 1, "agent_type": 1, "hetio_source": 1, "original_subject": 1, "original_object": 1 }, "subject_id_prefixes": { "CHEBI": 1 }, "object_id_prefixes": { "CHEBI": 1 } }, { "subject_category": [ "biolink:Drug" ], "predicate": "biolink:similar_to", "object_category": [ "biolink:ChemicalEntity" ], "count": 2, "primary_knowledge_sources": { "infores:hetionet": 2 }, "qualifiers": {}, "attributes": { "knowledge_level": 2, "agent_type": 2, "hetio_source": 2, "original_subject": 2, "original_object": 2 }, "subject_id_prefixes": { "CHEBI": 2 }, "object_id_prefixes": { "CHEBI": 2 } }, { "subject_category": [ "biolink:SmallMolecule" ], "predicate": "biolink:similar_to", "object_category": [ "biolink:MolecularMixture", "biolink:SmallMolecule" ], "count": 3, "primary_knowledge_sources": { "infores:hetionet": 3 }, "qualifiers": {}, "attributes": { "knowledge_level": 3, "agent_type": 3, "hetio_source": 3, "original_subject": 3, "original_object": 3 }, "subject_id_prefixes": { "CHEBI": 3 }, "object_id_prefixes": { "CHEBI": 3 } }, { "subject_category": [ "biolink:Drug" ], "predicate": "biolink:causes", "object_category": [ "biolink:Phenomenon" ], "count": 1, "primary_knowledge_sources": { "infores:sider": 1 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 1, "knowledge_level": 1, "agent_type": 1, "original_subject": 1, "original_object": 1 }, "subject_id_prefixes": { "PUBCHEM.COMPOUND": 1 }, "object_id_prefixes": { "UMLS": 1 } }, { "subject_category": [ "biolink:Protein" ], "predicate": "biolink:similar_to", "object_category": [ "biolink:SmallMolecule" ], "count": 10, "primary_knowledge_sources": { "infores:hetionet": 10 }, "qualifiers": {}, "attributes": { "knowledge_level": 10, "agent_type": 10, "hetio_source": 10, "original_subject": 10, "original_object": 10 }, "subject_id_prefixes": { "UMLS": 10 }, "object_id_prefixes": { "CHEBI": 9, "UNII": 1 } }, { "subject_category": [ "biolink:SmallMolecule" ], "predicate": "biolink:similar_to", "object_category": [ "biolink:ChemicalEntity" ], "count": 1, "primary_knowledge_sources": { "infores:hetionet": 1 }, "qualifiers": {}, "attributes": { "knowledge_level": 1, "agent_type": 1, "hetio_source": 1, "original_subject": 1, "original_object": 1 }, "subject_id_prefixes": { "CHEBI": 1 }, "object_id_prefixes": { "CHEBI": 1 } }, { "subject_category": [ "biolink:MolecularMixture" ], "predicate": "biolink:treats", "object_category": [ "biolink:Disease" ], "count": 2, "primary_knowledge_sources": { "infores:hetionet": 2 }, "qualifiers": {}, "attributes": { "knowledge_level": 2, "agent_type": 2, "hetio_source": 2, "original_subject": 2, "original_object": 2 }, "subject_id_prefixes": { "CHEBI": 1, "PUBCHEM.COMPOUND": 1 }, "object_id_prefixes": { "MONDO": 2 } }, { "subject_category": [ "biolink:Drug" ], "predicate": "biolink:causes", "object_category": [ "biolink:InformationContentEntity" ], "count": 1, "primary_knowledge_sources": { "infores:sider": 1 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 1, "knowledge_level": 1, "agent_type": 1, "original_subject": 1, "original_object": 1 }, "subject_id_prefixes": { "CHEBI": 1 }, "object_id_prefixes": { "UMLS": 1 } }, { "subject_category": [ "biolink:ChemicalEntity" ], "predicate": "biolink:similar_to", "object_category": [ "biolink:Drug", "biolink:SmallMolecule" ], "count": 1, "primary_knowledge_sources": { "infores:hetionet": 1 }, "qualifiers": {}, "attributes": { "knowledge_level": 1, "agent_type": 1, "hetio_source": 1, "original_subject": 1, "original_object": 1 }, "subject_id_prefixes": { "CHEBI": 1 }, "object_id_prefixes": { "CHEBI": 1 } }, { "subject_category": [ "biolink:SmallMolecule" ], "predicate": "biolink:causes", "object_category": [ "biolink:InformationContentEntity" ], "count": 1, "primary_knowledge_sources": { "infores:sider": 1 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 1, "knowledge_level": 1, "agent_type": 1, "original_subject": 1, "original_object": 1 }, "subject_id_prefixes": { "CHEBI": 1 }, "object_id_prefixes": { "UMLS": 1 } }, { "subject_category": [ "biolink:MolecularMixture", "biolink:SmallMolecule" ], "predicate": "biolink:similar_to", "object_category": [ "biolink:MolecularMixture", "biolink:SmallMolecule" ], "count": 1, "primary_knowledge_sources": { "infores:hetionet": 1 }, "qualifiers": {}, "attributes": { "knowledge_level": 1, "agent_type": 1, "hetio_source": 1, "original_subject": 1, "original_object": 1 }, "subject_id_prefixes": { "CHEBI": 1 }, "object_id_prefixes": { "CHEBI": 1 } }, { "subject_category": [ "biolink:ChemicalEntity" ], "predicate": "biolink:similar_to", "object_category": [ "biolink:Drug" ], "count": 1, "primary_knowledge_sources": { "infores:hetionet": 1 }, "qualifiers": {}, "attributes": { "knowledge_level": 1, "agent_type": 1, "hetio_source": 1, "original_subject": 1, "original_object": 1 }, "subject_id_prefixes": { "CHEBI": 1 }, "object_id_prefixes": { "CHEBI": 1 } }, { "subject_category": [ "biolink:MolecularMixture" ], "predicate": "biolink:causes", "object_category": [ "biolink:Behavior" ], "count": 1, "primary_knowledge_sources": { "infores:sider": 1 }, "qualifiers": {}, "attributes": { "aggregator_knowledge_source": 1, "knowledge_level": 1, "agent_type": 1, "original_subject": 1, "original_object": 1 }, "subject_id_prefixes": { "CHEBI": 1 }, "object_id_prefixes": { "UMLS": 1 } } ], "edges_summary": { "total_count": 1504968, "predicates": { "biolink:actively_involved_in": 498309, "biolink:regulates": 320719, "biolink:expressed_in": 157013, "biolink:genetically_interacts_with": 147139, "biolink:causes": 132801, "biolink:catalyzes": 82820, "biolink:has_part": 68699, "biolink:correlated_with": 61621, "biolink:related_to": 16223, "biolink:directly_physically_interacts_with": 11530, "biolink:similar_to": 6957, "biolink:treats": 752, "biolink:ameliorates_condition": 385 }, "primary_knowledge_sources": { "infores:hetionet": 909752, "infores:lincs": 305402, "infores:tissues-expression-db": 157013, "infores:sider": 132801 }, "predicates_by_knowledge_source": { "infores:hetionet": { "biolink:actively_involved_in": 498309, "biolink:genetically_interacts_with": 147139, "biolink:catalyzes": 82820, "biolink:has_part": 68699, "biolink:correlated_with": 61621, "biolink:related_to": 16223, "biolink:regulates": 15317, "biolink:directly_physically_interacts_with": 11530, "biolink:similar_to": 6957, "biolink:treats": 752, "biolink:ameliorates_condition": 385 }, "infores:tissues-expression-db": { "biolink:expressed_in": 157013 }, "infores:lincs": { "biolink:regulates": 305402 }, "infores:sider": { "biolink:causes": 132801 } }, "qualifiers": { "object_aspect_qualifier": 55052, "object_direction_qualifier": 55052, "qualified_predicate": 55052 }, "attributes": { "knowledge_level": 1504968, "agent_type": 1504968, "original_subject": 1504968, "original_object": 1504968, "hetio_source": 824907, "aggregator_knowledge_source": 680061 } } } }