{
  "@context": {
    "@vocab": "https://schema.org/",
    "biolink": "https://w3id.org/biolink/"
  },
  "@type": "Dataset",
  "@id": "https://robokop.renci.org/graphs/SIGNOR/1.0.0/schema.json",
  "name": "A ROBOKOP Knowledge Graph based on SIGnaling Network Open Resource (SIGNOR) Schema",
  "description": "Schema describing the nodes, edges, and attributes in the A ROBOKOP Knowledge Graph based on SIGnaling Network Open Resource (SIGNOR) knowledge graph",
  "encodingFormat": "application/ld+json",
  "isPartOf": {
    "@type": "Dataset",
    "@id": "https://robokop.renci.org/graphs/SIGNOR/1.0.0/",
    "name": "A ROBOKOP Knowledge Graph based on SIGnaling Network Open Resource (SIGNOR)"
  },
  "schema": {
    "nodes": [
      {
        "category": [
          "biolink:Protein"
        ],
        "count": 6448,
        "id_prefixes": {
          "UniProtKB": 6433,
          "UMLS": 15
        },
        "attributes": {
          "name": 6448,
          "equivalent_identifiers": 6448,
          "information_content": 6408,
          "description": 6408,
          "taxon": 6408
        }
      },
      {
        "category": [
          "biolink:SmallMolecule"
        ],
        "count": 214,
        "id_prefixes": {
          "CHEBI": 74,
          "UNII": 72,
          "PUBCHEM.COMPOUND": 68
        },
        "attributes": {
          "name": 214,
          "equivalent_identifiers": 214,
          "information_content": 74,
          "description": 39
        }
      },
      {
        "category": [
          "biolink:BiologicalProcess"
        ],
        "count": 66,
        "id_prefixes": {
          "GO": 66
        },
        "attributes": {
          "name": 66,
          "equivalent_identifiers": 66,
          "information_content": 66,
          "description": 66
        }
      },
      {
        "category": [
          "biolink:MolecularMixture"
        ],
        "count": 28,
        "id_prefixes": {
          "PUBCHEM.COMPOUND": 16,
          "UNII": 7,
          "CHEBI": 5
        },
        "attributes": {
          "name": 28,
          "equivalent_identifiers": 28,
          "information_content": 5,
          "description": 4
        }
      },
      {
        "category": [
          "biolink:ChemicalEntity"
        ],
        "count": 5,
        "id_prefixes": {
          "UNII": 4,
          "DRUGBANK": 1
        },
        "attributes": {
          "name": 5,
          "equivalent_identifiers": 5
        }
      },
      {
        "category": [
          "biolink:Pathway"
        ],
        "count": 1,
        "id_prefixes": {
          "GO": 1
        },
        "attributes": {
          "name": 1,
          "equivalent_identifiers": 1,
          "information_content": 1,
          "description": 1
        }
      }
    ],
    "nodes_summary": {
      "total_count": 6762,
      "id_prefixes": {
        "UniProtKB": 6433,
        "PUBCHEM.COMPOUND": 84,
        "UNII": 83,
        "CHEBI": 79,
        "GO": 67,
        "UMLS": 15,
        "DRUGBANK": 1
      },
      "attributes": {
        "name": 6762,
        "equivalent_identifiers": 6762,
        "information_content": 6554,
        "description": 6518,
        "taxon": 6408
      }
    },
    "edges": [
      {
        "subject_category": [
          "biolink:Protein"
        ],
        "predicate": "biolink:related_to",
        "object_category": [
          "biolink:Protein"
        ],
        "count": 21137,
        "primary_knowledge_sources": {
          "infores:signor": 21137
        },
        "qualifiers": {
          "species_context_qualifier": 18933,
          "anatomical_context_qualifier": 9391,
          "subject_part_qualifier": 25,
          "object_part_qualifier": 18
        },
        "attributes": {
          "knowledge_level": 21137,
          "agent_type": 21137,
          "publications": 21137,
          "description": 21137,
          "original_subject": 21137,
          "original_object": 21137
        },
        "subject_id_prefixes": {
          "UniProtKB": 21117,
          "UMLS": 20
        },
        "object_id_prefixes": {
          "UniProtKB": 21137
        }
      },
      {
        "subject_category": [
          "biolink:Protein"
        ],
        "predicate": "biolink:regulates",
        "object_category": [
          "biolink:Protein"
        ],
        "count": 21805,
        "primary_knowledge_sources": {
          "infores:signor": 21805
        },
        "qualifiers": {
          "object_direction_qualifier": 21805,
          "species_context_qualifier": 19753,
          "object_aspect_qualifier": 15994,
          "anatomical_context_qualifier": 9661,
          "subject_part_qualifier": 34,
          "object_part_qualifier": 19
        },
        "attributes": {
          "knowledge_level": 21805,
          "agent_type": 21805,
          "publications": 21805,
          "description": 21805,
          "original_subject": 21805,
          "original_object": 21805
        },
        "subject_id_prefixes": {
          "UniProtKB": 21785,
          "UMLS": 20
        },
        "object_id_prefixes": {
          "UniProtKB": 21805
        }
      },
      {
        "subject_category": [
          "biolink:Protein"
        ],
        "predicate": "biolink:affects",
        "object_category": [
          "biolink:Protein"
        ],
        "count": 5162,
        "primary_knowledge_sources": {
          "infores:signor": 5162
        },
        "qualifiers": {
          "qualified_predicate": 5162,
          "object_direction_qualifier": 5162,
          "object_aspect_qualifier": 5162,
          "species_context_qualifier": 4687,
          "anatomical_context_qualifier": 2702,
          "object_part_qualifier": 4,
          "subject_part_qualifier": 1
        },
        "attributes": {
          "knowledge_level": 5162,
          "agent_type": 5162,
          "publications": 5162,
          "description": 5162,
          "original_subject": 5162,
          "original_object": 5162
        },
        "subject_id_prefixes": {
          "UniProtKB": 5162
        },
        "object_id_prefixes": {
          "UniProtKB": 5162
        }
      },
      {
        "subject_category": [
          "biolink:SmallMolecule"
        ],
        "predicate": "biolink:related_to",
        "object_category": [
          "biolink:Protein"
        ],
        "count": 365,
        "primary_knowledge_sources": {
          "infores:signor": 365
        },
        "qualifiers": {
          "species_context_qualifier": 304,
          "anatomical_context_qualifier": 83
        },
        "attributes": {
          "knowledge_level": 365,
          "agent_type": 365,
          "publications": 365,
          "description": 365,
          "original_subject": 365,
          "original_object": 365
        },
        "subject_id_prefixes": {
          "CHEBI": 138,
          "UNII": 133,
          "PUBCHEM.COMPOUND": 94
        },
        "object_id_prefixes": {
          "UniProtKB": 365
        }
      },
      {
        "subject_category": [
          "biolink:SmallMolecule"
        ],
        "predicate": "biolink:regulates",
        "object_category": [
          "biolink:Protein"
        ],
        "count": 369,
        "primary_knowledge_sources": {
          "infores:signor": 369
        },
        "qualifiers": {
          "object_direction_qualifier": 369,
          "species_context_qualifier": 308,
          "object_aspect_qualifier": 171,
          "anatomical_context_qualifier": 83
        },
        "attributes": {
          "knowledge_level": 369,
          "agent_type": 369,
          "publications": 369,
          "description": 369,
          "original_subject": 369,
          "original_object": 369
        },
        "subject_id_prefixes": {
          "CHEBI": 140,
          "UNII": 134,
          "PUBCHEM.COMPOUND": 95
        },
        "object_id_prefixes": {
          "UniProtKB": 369
        }
      },
      {
        "subject_category": [
          "biolink:Protein"
        ],
        "predicate": "biolink:regulates",
        "object_category": [
          "biolink:BiologicalProcess"
        ],
        "count": 375,
        "primary_knowledge_sources": {
          "infores:signor": 375
        },
        "qualifiers": {
          "object_direction_qualifier": 375,
          "species_context_qualifier": 299,
          "anatomical_context_qualifier": 136,
          "object_aspect_qualifier": 24
        },
        "attributes": {
          "knowledge_level": 375,
          "agent_type": 375,
          "publications": 375,
          "description": 375,
          "original_subject": 375,
          "original_object": 375
        },
        "subject_id_prefixes": {
          "UniProtKB": 375
        },
        "object_id_prefixes": {
          "GO": 375
        }
      },
      {
        "subject_category": [
          "biolink:MolecularMixture"
        ],
        "predicate": "biolink:related_to",
        "object_category": [
          "biolink:Protein"
        ],
        "count": 42,
        "primary_knowledge_sources": {
          "infores:signor": 42
        },
        "qualifiers": {
          "species_context_qualifier": 38,
          "anatomical_context_qualifier": 6
        },
        "attributes": {
          "knowledge_level": 42,
          "agent_type": 42,
          "publications": 42,
          "description": 42,
          "original_subject": 42,
          "original_object": 42
        },
        "subject_id_prefixes": {
          "PUBCHEM.COMPOUND": 26,
          "UNII": 11,
          "CHEBI": 5
        },
        "object_id_prefixes": {
          "UniProtKB": 42
        }
      },
      {
        "subject_category": [
          "biolink:MolecularMixture"
        ],
        "predicate": "biolink:regulates",
        "object_category": [
          "biolink:Protein"
        ],
        "count": 42,
        "primary_knowledge_sources": {
          "infores:signor": 42
        },
        "qualifiers": {
          "object_direction_qualifier": 42,
          "species_context_qualifier": 38,
          "object_aspect_qualifier": 12,
          "anatomical_context_qualifier": 6
        },
        "attributes": {
          "knowledge_level": 42,
          "agent_type": 42,
          "publications": 42,
          "description": 42,
          "original_subject": 42,
          "original_object": 42
        },
        "subject_id_prefixes": {
          "PUBCHEM.COMPOUND": 26,
          "UNII": 11,
          "CHEBI": 5
        },
        "object_id_prefixes": {
          "UniProtKB": 42
        }
      },
      {
        "subject_category": [
          "biolink:ChemicalEntity"
        ],
        "predicate": "biolink:related_to",
        "object_category": [
          "biolink:Protein"
        ],
        "count": 6,
        "primary_knowledge_sources": {
          "infores:signor": 6
        },
        "qualifiers": {
          "species_context_qualifier": 6,
          "anatomical_context_qualifier": 2
        },
        "attributes": {
          "knowledge_level": 6,
          "agent_type": 6,
          "publications": 6,
          "description": 6,
          "original_subject": 6,
          "original_object": 6
        },
        "subject_id_prefixes": {
          "UNII": 5,
          "DRUGBANK": 1
        },
        "object_id_prefixes": {
          "UniProtKB": 6
        }
      },
      {
        "subject_category": [
          "biolink:ChemicalEntity"
        ],
        "predicate": "biolink:regulates",
        "object_category": [
          "biolink:Protein"
        ],
        "count": 6,
        "primary_knowledge_sources": {
          "infores:signor": 6
        },
        "qualifiers": {
          "species_context_qualifier": 6,
          "object_direction_qualifier": 6,
          "object_aspect_qualifier": 6,
          "anatomical_context_qualifier": 2
        },
        "attributes": {
          "knowledge_level": 6,
          "agent_type": 6,
          "publications": 6,
          "description": 6,
          "original_subject": 6,
          "original_object": 6
        },
        "subject_id_prefixes": {
          "UNII": 5,
          "DRUGBANK": 1
        },
        "object_id_prefixes": {
          "UniProtKB": 6
        }
      },
      {
        "subject_category": [
          "biolink:Protein"
        ],
        "predicate": "biolink:regulates",
        "object_category": [
          "biolink:SmallMolecule"
        ],
        "count": 6,
        "primary_knowledge_sources": {
          "infores:signor": 6
        },
        "qualifiers": {
          "object_direction_qualifier": 6,
          "species_context_qualifier": 5,
          "object_aspect_qualifier": 3,
          "subject_part_qualifier": 1
        },
        "attributes": {
          "knowledge_level": 6,
          "agent_type": 6,
          "publications": 6,
          "description": 6,
          "original_subject": 6,
          "original_object": 6
        },
        "subject_id_prefixes": {
          "UniProtKB": 6
        },
        "object_id_prefixes": {
          "CHEBI": 4,
          "PUBCHEM.COMPOUND": 2
        }
      },
      {
        "subject_category": [
          "biolink:Protein"
        ],
        "predicate": "biolink:related_to",
        "object_category": [
          "biolink:SmallMolecule"
        ],
        "count": 5,
        "primary_knowledge_sources": {
          "infores:signor": 5
        },
        "qualifiers": {
          "species_context_qualifier": 4,
          "subject_part_qualifier": 1
        },
        "attributes": {
          "knowledge_level": 5,
          "agent_type": 5,
          "publications": 5,
          "description": 5,
          "original_subject": 5,
          "original_object": 5
        },
        "subject_id_prefixes": {
          "UniProtKB": 5
        },
        "object_id_prefixes": {
          "CHEBI": 3,
          "PUBCHEM.COMPOUND": 2
        }
      },
      {
        "subject_category": [
          "biolink:Protein"
        ],
        "predicate": "biolink:related_to",
        "object_category": [
          "biolink:BiologicalProcess"
        ],
        "count": 5,
        "primary_knowledge_sources": {
          "infores:signor": 5
        },
        "qualifiers": {
          "species_context_qualifier": 5,
          "anatomical_context_qualifier": 2
        },
        "attributes": {
          "knowledge_level": 5,
          "agent_type": 5,
          "publications": 5,
          "description": 5,
          "original_subject": 5,
          "original_object": 5
        },
        "subject_id_prefixes": {
          "UniProtKB": 5
        },
        "object_id_prefixes": {
          "GO": 5
        }
      },
      {
        "subject_category": [
          "biolink:BiologicalProcess"
        ],
        "predicate": "biolink:regulates",
        "object_category": [
          "biolink:Protein"
        ],
        "count": 7,
        "primary_knowledge_sources": {
          "infores:signor": 7
        },
        "qualifiers": {
          "object_direction_qualifier": 7,
          "object_aspect_qualifier": 6,
          "anatomical_context_qualifier": 5,
          "species_context_qualifier": 4
        },
        "attributes": {
          "knowledge_level": 7,
          "agent_type": 7,
          "publications": 7,
          "description": 7,
          "original_subject": 7,
          "original_object": 7
        },
        "subject_id_prefixes": {
          "GO": 7
        },
        "object_id_prefixes": {
          "UniProtKB": 7
        }
      },
      {
        "subject_category": [
          "biolink:Protein"
        ],
        "predicate": "biolink:affects",
        "object_category": [
          "biolink:BiologicalProcess"
        ],
        "count": 1,
        "primary_knowledge_sources": {
          "infores:signor": 1
        },
        "qualifiers": {
          "species_context_qualifier": 1,
          "anatomical_context_qualifier": 1,
          "qualified_predicate": 1,
          "object_direction_qualifier": 1,
          "object_aspect_qualifier": 1
        },
        "attributes": {
          "knowledge_level": 1,
          "agent_type": 1,
          "publications": 1,
          "description": 1,
          "original_subject": 1,
          "original_object": 1
        },
        "subject_id_prefixes": {
          "UniProtKB": 1
        },
        "object_id_prefixes": {
          "GO": 1
        }
      },
      {
        "subject_category": [
          "biolink:Protein"
        ],
        "predicate": "biolink:in_complex_with",
        "object_category": [
          "biolink:Protein"
        ],
        "count": 2,
        "primary_knowledge_sources": {
          "infores:signor": 2
        },
        "qualifiers": {
          "species_context_qualifier": 2
        },
        "attributes": {
          "knowledge_level": 2,
          "agent_type": 2,
          "publications": 2,
          "description": 2,
          "original_subject": 2,
          "original_object": 2
        },
        "subject_id_prefixes": {
          "UniProtKB": 2
        },
        "object_id_prefixes": {
          "UniProtKB": 2
        }
      },
      {
        "subject_category": [
          "biolink:Protein"
        ],
        "predicate": "biolink:directly_physically_interacts_with",
        "object_category": [
          "biolink:Protein"
        ],
        "count": 2,
        "primary_knowledge_sources": {
          "infores:signor": 2
        },
        "qualifiers": {
          "species_context_qualifier": 2
        },
        "attributes": {
          "knowledge_level": 2,
          "agent_type": 2,
          "publications": 2,
          "description": 2,
          "original_subject": 2,
          "original_object": 2
        },
        "subject_id_prefixes": {
          "UniProtKB": 2
        },
        "object_id_prefixes": {
          "UniProtKB": 2
        }
      },
      {
        "subject_category": [
          "biolink:Protein"
        ],
        "predicate": "biolink:related_to",
        "object_category": [
          "biolink:Pathway"
        ],
        "count": 1,
        "primary_knowledge_sources": {
          "infores:signor": 1
        },
        "qualifiers": {},
        "attributes": {
          "knowledge_level": 1,
          "agent_type": 1,
          "publications": 1,
          "description": 1,
          "original_subject": 1,
          "original_object": 1
        },
        "subject_id_prefixes": {
          "UniProtKB": 1
        },
        "object_id_prefixes": {
          "GO": 1
        }
      },
      {
        "subject_category": [
          "biolink:Protein"
        ],
        "predicate": "biolink:regulates",
        "object_category": [
          "biolink:Pathway"
        ],
        "count": 1,
        "primary_knowledge_sources": {
          "infores:signor": 1
        },
        "qualifiers": {
          "object_direction_qualifier": 1
        },
        "attributes": {
          "knowledge_level": 1,
          "agent_type": 1,
          "publications": 1,
          "description": 1,
          "original_subject": 1,
          "original_object": 1
        },
        "subject_id_prefixes": {
          "UniProtKB": 1
        },
        "object_id_prefixes": {
          "GO": 1
        }
      },
      {
        "subject_category": [
          "biolink:BiologicalProcess"
        ],
        "predicate": "biolink:regulates",
        "object_category": [
          "biolink:BiologicalProcess"
        ],
        "count": 1,
        "primary_knowledge_sources": {
          "infores:signor": 1
        },
        "qualifiers": {
          "species_context_qualifier": 1,
          "anatomical_context_qualifier": 1,
          "object_direction_qualifier": 1
        },
        "attributes": {
          "knowledge_level": 1,
          "agent_type": 1,
          "publications": 1,
          "description": 1,
          "original_subject": 1,
          "original_object": 1
        },
        "subject_id_prefixes": {
          "GO": 1
        },
        "object_id_prefixes": {
          "GO": 1
        }
      }
    ],
    "edges_summary": {
      "total_count": 49340,
      "predicates": {
        "biolink:regulates": 22612,
        "biolink:related_to": 21561,
        "biolink:affects": 5163,
        "biolink:in_complex_with": 2,
        "biolink:directly_physically_interacts_with": 2
      },
      "primary_knowledge_sources": {
        "infores:signor": 49340
      },
      "predicates_by_knowledge_source": {
        "infores:signor": {
          "biolink:regulates": 22612,
          "biolink:related_to": 21561,
          "biolink:affects": 5163,
          "biolink:in_complex_with": 2,
          "biolink:directly_physically_interacts_with": 2
        }
      },
      "qualifiers": {
        "species_context_qualifier": 44396,
        "object_direction_qualifier": 27775,
        "anatomical_context_qualifier": 22081,
        "object_aspect_qualifier": 21379,
        "qualified_predicate": 5163,
        "subject_part_qualifier": 62,
        "object_part_qualifier": 41
      },
      "attributes": {
        "knowledge_level": 49340,
        "agent_type": 49340,
        "publications": 49340,
        "description": 49340,
        "original_subject": 49340,
        "original_object": 49340
      }
    }
  }
}