congenital cataract-microcephaly-nevus flammeus simplex-severe intellectual disability syndrome


hereditary spastic paraplegia 74

biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing


developmental and epileptic encephalopathy, 50


intellectual disability, autosomal recessive 50


progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal recessive 2


microcephaly 15, primary, autosomal recessive


epidermolysis bullosa simplex with nail dystrophy


congenital insensitivity to pain-hypohidrosis syndrome


Charcot-Marie-Tooth disease axonal type 2V


lethal congenital contracture syndrome 9


neuropathy, hereditary motor and sensory, type 6B


maturity-onset diabetes of the young type 14


autosomal recessive nonsyndromic hearing loss 104


intellectual disability, autosomal dominant 39


combined oxidative phosphorylation defect type 26


Klippel-Feil anomaly-myopathy-facial dysmorphism syndrome


microcephaly-intellectual disability-sensorineural hearing loss-epilepsy-abnormal muscle tone syndrome


intellectual disability, autosomal dominant 40


autosomal recessive complex spastic paraplegia type 9B


skeletal overgrowth-craniofacial dysmorphism-hyperelastic skin-white matter lesions syndrome


autosomal recessive mendelian susceptibility to mycobacterial diseases due to complete RORgamma receptor deficiency


autosomal dominant Charcot-Marie-Tooth disease type 2W


progressive microcephaly-seizures-cortical blindness-developmental delay syndrome


primary immunodeficiency with post-measles-mumps-rubella vaccine viral infection


developmental and epileptic encephalopathy, 34


developmental and epileptic encephalopathy, 35


Charcot-Marie-Tooth disease axonal type 2X


combined oxidative phosphorylation defect type 27


microcephaly 16, primary, autosomal recessive


Charcot-Marie-Tooth disease axonal type 2Z


autosomal dominant nonsyndromic hearing loss 69


autosomal recessive nonsyndromic hearing loss 97


autosomal dominant nonsyndromic hearing loss 68


DeSanto-Shinawi syndrome due to WAC point mutation


Parkinson disease 22, autosomal dominant


rhizomelic chondrodysplasia punctata type 5


familial progressive retinal dystrophy-iris coloboma-congenital cataract syndrome


palatal anomalies-widely spaced teeth-facial dysmorphism-developmental delay syndrome


macrothrombocytopenia-lymphedema-developmental delay-facial dysmorphism-camptodactyly syndrome


intellectual disability, autosomal recessive 51


leukodystrophy and acquired microcephaly with or without dystonia;


cardiac anomalies - developmental delay - facial dysmorphism syndrome


combined oxidative phosphorylation deficiency 28


hypotonia, infantile, with psychomotor retardation and characteristic facies 2


combined oxidative phosphorylation deficiency 29


autosomal recessive limb-girdle muscular dystrophy type 2X


severe hypotonia-psychomotor developmental delay-strabismus-cardiac septal defect syndrome


microcephaly, short stature, and impaired glucose metabolism 2


severe intellectual disability-corpus callosum agenesis-facial dysmorphism-cerebellar ataxia syndrome


autosomal recessive limb-girdle muscular dystrophy type 2W


microcephaly-congenital cataract-psoriasiform dermatitis syndrome


autosomal recessive early-onset Parkinson disease 23


progressive scapulohumeroperoneal distal myopathy


spinal muscular atrophy with congenital bone fractures 1


spinal muscular atrophy with congenital bone fractures 2


cerebellar atrophy, visual impairment, and psychomotor retardation;


intellectual disability, autosomal recessive 52


split-foot malformation-mesoaxial polydactyly syndrome


mitochondrial DNA depletion syndrome 14 (cardioencephalomyopathic type)


hypotonia, infantile, with psychomotor retardation and characteristic facies 3


autosomal recessive spastic paraplegia type 76


immunodeficiency-centromeric instability-facial anomalies syndrome 3


immunodeficiency-centromeric instability-facial anomalies syndrome 4


progeroid and marfanoid aspect-lipodystrophy syndrome


intellectual disability, autosomal recessive 53


striatal degeneration, autosomal dominant 2


Charcot-Marie-Tooth disease axonal type 2CC


chorea, childhood-onset, with psychomotor retardation


intellectual disability, autosomal dominant 41


TELO2-related intellectual disability-neurodevelopmental disorder


retinitis pigmentosa and erythrocytic microcytosis


autosomal dominant nonsyndromic hearing loss 70


autosomal dominant nonsyndromic hearing loss 66


intellectual disability, autosomal dominant 42


combined oxidative phosphorylation defect type 30


neurodevelopmental disorder with or without anomalies of the brain, eye, or heart


intellectual disability, autosomal dominant 43


developmental and epileptic encephalopathy, 37


autoimmune disease, multisystem, infantile-onset, 2


macrocephaly, dysmorphic facies, and psychomotor retardation


autosomal recessive severe congenital neutropenia due to CSF3R deficiency


Charcot-Marie-Tooth disease axonal type 2T


developmental and epileptic encephalopathy, 38


hydrops-lactic acidosis-sideroblastic anemia-multisystemic failure syndrome


intellectual disability, autosomal recessive 54


cholestasis, progressive familial intrahepatic, 5


severe growth deficiency-strabismus-extensive dermal melanocytosis-intellectual disability syndrome


hyperuricemic nephropathy, familial juvenile type 4


micrognathia-recurrent infections-behavioral abnormalities-mild intellectual disability syndrome


developmental and epileptic encephalopathy, 40


congenital muscular dystrophy-respiratory failure-skin abnormalities-joint hyperlaxity syndrome


progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal recessive 3


progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal recessive 4


autosomal recessive limb-girdle muscular dystrophy type 2Y


congenital disorder of glycosylation, type IAA


encephalopathy due to defective mitochondrial and peroxisomal fission 2


Charcot-Marie-Tooth disease, axonal, autosomal recessive, type 2a2b;


microcephaly 17, primary, autosomal recessive


growth retardation, intellectual developmental disorder, hypotonia, and hepatopathy


autoinflammation, panniculitis, and dermatosis syndrome, autosomal recessive


developmental and epileptic encephalopathy, 41


developmental and epileptic encephalopathy, 42


tall stature-intellectual disability-renal anomalies syndrome


developmental and epileptic encephalopathy, 43


intellectual disability, autosomal recessive 56


developmental and epileptic encephalopathy, 44


neurodegeneration with ataxia, dystonia, and gaze palsy, childhood-onset


arthrogryposis, distal, with impaired proprioception and touch


developmental and epileptic encephalopathy, 45


mitochondrial DNA depletion syndrome 15 (hepatocerebral type)


developmental and epileptic encephalopathy, 46


developmental and epileptic encephalopathy, 47


gnb5-related intellectual disability-cardiac arrhythmia syndrome


Ehlers-Danlos syndrome, periodontal type 2


language delay and attention deficit-hyperactivity disorder/cognitive impairment with or without cardiac arrhythmia


mitochondrial DNA depletion syndrome 12A (cardiomyopathic type), autosomal dominant


intellectual disability, autosomal recessive 57


lethal congenital contracture syndrome 11


encephalopathy, progressive, with amyotrophy and optic atrophy


amelogenesis imperfecta, hypomaturation type, IIa6


autosomal recessive spastic paraplegia type 78


lethal left ventricular non-compaction-seizures-hypotonia-cataract-developmental delay syndrome


autosomal recessive limb-girdle muscular dystrophy type 2R1


lung disease, immunodeficiency, and chromosome breakage syndrome;


global developmental delay, absent or hypoplastic corpus callosum, and dysmorphic facies


neurodevelopmental disorder with hypotonia, seizures, and absent language


intellectual disability, autosomal recessive 58


developmental and epileptic encephalopathy, 48


developmental and epileptic encephalopathy, 49


epidermolysis bullosa simplex 6, generalized, with scarring and hair loss


coloboma, osteopetrosis, microphthalmia, macrocephaly, albinism, and deafness


ichthyosis, congenital, autosomal recessive 12


intellectual disability, autosomal recessive 59


hypotonia, ataxia, and delayed development syndrome


intellectual developmental disorder with dysmorphic facies and ptosis


ectodermal dysplasia 12, hypohidrotic/hair/tooth/nail type


developmental and epileptic encephalopathy, 51


drug rash with eosinophilia and systemic symptoms


hereditary sensory and autonomic neuropathy


anti-neutrophil cytoplasmic antibody-associated vasculitis


macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss


eosinophilic granulomatosis with polyangiitis


46,XX ovotesticular disorder of sex development


foveal hypoplasia-presenile cataract syndrome


autosomal recessive hypohidrotic ectodermal dysplasia


autosomal recessive progressive external ophthalmoplegia


mitochondrial myopathy-lactic acidosis-deafness syndrome


methylmalonic aciduria and homocystinuria


heritable pulmonary arterial hypertension


frontotemporal dementia with motor neuron disease


fatal multiple mitochondrial dysfunctions syndrome


acute generalized exanthematous pustulosis


hypoplastic pancreas-intestinal atresia-hypoplastic gallbalder syndrome


inherited glutathione synthetase deficiency


catecholaminergic polymorphic ventricular tachycardia


Koolen-de Vries syndrome due to 17q21.31 microdeletion syndrome


peripheral primitive neuroectodermal tumor


neurodegeneration with brain iron accumulation


autosomal recessive distal renal tubular acidosis


microcephalic primordial dwarfism due to RTTN deficiency


isolated neonatal sclerosing cholangitis


distal myopathy with vocal cord weakness


patterned dystrophy of the retinal pigment epithelium


spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 2


hereditary thrombophilia due to congenital protein C deficiency


inborn disorder of purine or pyrimidine metabolism


infantile neuronal ceroid lipofuscinosis


punctate palmoplantar keratoderma type 1


steroid-responsive encephalopathy associated with autoimmune thyroiditis


oligoarticular juvenile idiopathic arthritis


myelodysplastic syndrome with excess blasts


T-cell large granular lymphocyte leukemia


subcutaneous panniculitis-like T-cell lymphoma


hereditary motor and sensory neuropathy type 6


spondyloepimetaphyseal dysplasia, PAPSS2 type


acquired thrombotic thrombocytopenic purpura


familial focal epilepsy with variable foci


sulfite oxidase deficiency due to molybdenum cofactor deficiency


Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis


combined oxidative phosphorylation deficiency 22


optic atrophy 10 with or without ataxia, intellectual disability, and seizures


encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy, 1


hypomagnesemia, seizures, and intellectual disability 1


autosomal dominant limb-girdle muscular dystrophy type 1D (DNAJB6)


craniodiaphyseal dysplasia, autosomal dominant


temporomandibular joint dysfunction syndrome


hypothyroidism, congenital, nongoitrous, 2


skin disease caused by bacterial infection


neuropathy, hereditary sensory and autonomic, type 2A


circadian rhythm sleep disorder, jet lag type


neurodegeneration with brain iron accumulation 2A


pituitary hormone deficiency, combined, 1


surfactant metabolism dysfunction, pulmonary, 2


digestive system neuroendocrine neoplasm


dyschromatosis universalis hereditaria 1


ectodermal dysplasia-syndactyly syndrome 1


hypotonia, infantile, with psychomotor retardation and characteristic facies 1


congenital muscular dystrophy with cataracts and intellectual disability


central nervous system infectious disorder


gastroenteritis, transmissible, of swine


simian acquired immunodeficiency syndrome


murine acquired immunodeficiency syndrome


porcine reproductive and respiratory syndrome


famililal cerebral cavernous malformations


microcephaly, epilepsy, and diabetes syndrome 1


developmental and epileptic encephalopathy, 52


developmental and epileptic encephalopathy, 53


developmental and epileptic encephalopathy, 54


neurodevelopmental disorder with progressive spasticity and brain white matter abnormalities


mitochondrial complex IV deficiency, nuclear-type


neutropenia, severe congenital, 1, autosomal dominant


hearing loss, mixed conductive-sensorineural


otospondylomegaepiphyseal dysplasia, autosomal recessive


aortic aneurysm, familial thoracic 11, susceptibility to


congenital heart defects, dysmorphic facial features, and intellectual developmental disorder


congenital heart defects and ectodermal dysplasia


hyperphenylalaninemia due to DNAJC12 deficiency


ectodermal dysplasia 13, hair/tooth type


neurodevelopmental disorder with epilepsy, cataracts, feeding difficulties, and delayed brain myelination


brachycephaly, trichomegaly, and developmental delay


immunoskeletal dysplasia with neurodevelopmental abnormalities


intellectual disability, autosomal recessive 60


thrombocytopenia, anemia, and myelofibrosis


intellectual developmental disorder with gastrointestinal difficulties and high pain threshold


intellectual developmental disorder with dysmorphic facies, seizures, and distal limb anomalies


infantile-onset generalized dyskinesia with orofacial involvement


early-onset progressive diffuse brain atrophy-microcephaly-muscle weakness-optic atrophy syndrome


menstrual cycle-dependent periodic fever


congenital disorder of glycosylation, type IIq


Noonan syndrome-like disorder with loose anagen hair 1


autoinflammation with arthritis and dyskeratosis


arthrogryposis multiplex congenita 1, neurogenic, with myelin defect


susceptibility to angioedema induced by ACE inhibitors


adult acute respiratory distress syndrome


growth hormone insensitivity with immune dysregulation 1, autosomal recessive


IFAP syndrome 1, with or without BRESHECK syndrome


Rajab interstitial lung disease with brain calcifications 1


paroxysmal familial ventricular fibrillation


familial hyperphosphatemic tumoral calcinosis/hyperphosphatemic hyperostosis syndrome


mitochondrial complex II deficiency, nuclear type 1


neuronopathy, distal hereditary motor, type 5


short stature and advanced bone age, with or without early-onset osteoarthritis and/or osteochondritis dissecans


brain malformations with or without urinary tract defects


mitochondrial DNA depletion syndrome, hepatocerebral form


leukoencephalopathy, diffuse hereditary, with spheroids 1


dyskinesia with orofacial involvement, autosomal dominant


central hypoventilation syndrome, congenital


congenital disorder of deglycosylation 1


autoinflammatory syndrome, familial, Behcet-like 1


macrothrombocytopenia, isolated, 1, autosomal dominant


fibrosis of extraocular muscles, congenital, 3b


efavirenz central nervous system toxicity, susceptibility to


developmental delay with short stature, dysmorphic facial features, and sparse hair 1


congenital amegakaryocytic thrombocytopenia 1


visceral neuropathy, familial, 1, autosomal recessive


neurologic, endocrine, and pancreatic disease, multisystem, infantile-onset 1


autoimmune lymphoproliferative syndrome, type III caused by mutation in PRKCD


Failure to Thrive

biolink:PhenotypicFeature biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing


URIC ACID CONCENTRATION, SERUM, QUANTITATIVE TRAIT LOCUS 1


Juvenile Polyposis with Hereditary Hemorrhagic Telangiectasia


Trichorhinophalangeal Syndrome, Type III


Cafe-au-lait macules with pulmonary stenosis


PLASMODIUM FALCIPARUM BLOOD INFECTION LEVEL


Retinitis Pigmentosa, X-Linked, And Sinorespiratory Infections, With Or Without Deafness


BONE MINERAL DENSITY QUANTITATIVE TRAIT LOCUS 18


Platelet Disorder, Familial, with Associated Myeloid Malignancy


BODY MASS INDEX QUANTITATIVE TRAIT LOCUS 9


PROSTATE CANCER/BRAIN CANCER SUSCEPTIBILITY


DEAFNESS, AUTOSOMAL RECESSIVE 26, MODIFIER OF


ADIPONECTIN, SERUM LEVEL OF, QUANTITATIVE TRAIT LOCUS 2


ADIPONECTIN, SERUM LEVEL OF, QUANTITATIVE TRAIT LOCUS 3


BODY MASS INDEX QUANTITATIVE TRAIT LOCUS 4


BODY MASS INDEX QUANTITATIVE TRAIT LOCUS 10


Hereditary Non-Polyposis Colon Cancer Type 2


Neutropenia, Severe Congenital, Autosomal Recessive 3


HIGH DENSITY LIPOPROTEIN CHOLESTEROL LEVEL QUANTITATIVE TRAIT LOCUS 6


BODY MASS INDEX QUANTITATIVE TRAIT LOCUS 12


BODY MASS INDEX QUANTITATIVE TRAIT LOCUS 14


VITAMIN B12 PLASMA LEVEL QUANTITATIVE TRAIT LOCUS 1


BONE MINERAL DENSITY QUANTITATIVE TRAIT LOCUS 12


URIC ACID CONCENTRATION, SERUM, QUANTITATIVE TRAIT LOCUS 4


HIGH DENSITY LIPOPROTEIN CHOLESTEROL LEVEL QUANTITATIVE TRAIT LOCUS 12


COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 8


Rhabdoid Tumor Predisposition Syndrome 2


BONE MINERAL DENSITY QUANTITATIVE TRAIT LOCUS 15


DYSKERATOSIS CONGENITA, AUTOSOMAL RECESSIVE 2


Dyskeratosis Congenita, Autosomal Recessive 3


DYSKERATOSIS CONGENITA, AUTOSOMAL DOMINANT 2


Dyskeratosis Congenita, Autosomal Dominant 3


COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 6


COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 4


COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5


Colorectal Cancer, Hereditary Nonpolyposis, Type 7


CUTANEOUS TELANGIECTASIA AND CANCER SYNDROME, FAMILIAL


IMMUNODEFICIENCY, COMMON VARIABLE, 8, WITH AUTOIMMUNITY


DYSKERATOSIS CONGENITA, AUTOSOMAL RECESSIVE 5


BONE MINERAL DENSITY QUANTITATIVE TRAIT LOCUS 17


BODY MASS INDEX QUANTITATIVE TRAIT LOCUS 18


MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 10


Progeroid features, hepatocellular carcinoma predisposition syndrome


DYSKERATOSIS CONGENITA, AUTOSOMAL RECESSIVE 6


PULMONARY FIBROSIS AND/OR BONE MARROW FAILURE SYNDROME, TELOMERE-RELATED, 3


DYSKERATOSIS CONGENITA, AUTOSOMAL RECESSIVE 7


OOCYTE/ZYGOTE/EMBRYO MATURATION ARREST 15


MYELOPROLIFERATIVE/LYMPHOPROLIFERATIVE NEOPLASMS, FAMILIAL (MULTIPLE TYPES), SUSCEPTIBILITY TO


OOCYTE/ZYGOTE/EMBRYO MATURATION ARREST 16


cyclohexylcarbamic acid biphenyl-3-yl ester


sodium p-perfluorous nonenoxybenzene sulfonate


Cyproterone acetate, ethinyl estradiol drug combination


Aspirin-oxycodone hydrochloride-oxycodone terephthalate combination


aspirin, codeine, phenacetin drug combination


acetaminophen, dextropropoxyphene, drug combination


3-adenin-9-yl-2-hydroxypropanoic acid isobutyl ester


chromium (III) beta,gamma-bidentate guanosine triphosphate


chromium (III) bidentate guanosine 5'-(beta,gamma-imido)triphosphate


pyridoxal phosphate gamma-glutamyl hydrazone


5-pregnene-3 beta,17 alpha,20 alpha-triol


Corticotropin-Like Intermediate Lobe Peptide


pyridoxal phosphate gamma-aminobutyric acid


ethosuximide, quinacrine drug combination


amphotericin B, deoxycholate drug combination


aspirin, butalbital and caffeine drug combination


Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide


1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester


3,5-dibromo-4-(3,4-dimethoxyphenyl)-1H-pyrrole-2-carboxylic acid ethyl ester


15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid


enkephalin-Leu, Ala(2)-melphalan methyl ester-


somatotropin releasing hormone (1-29)-amide, N-Ac-Tyr(1)-Phe(2)-


vasoactive intestinal peptide, 4-chloro-Phe(6)-Leu(17)-


4-amidinocyclohexanecarboxylic acid 4-tert-butylphenyl ester


norethindrone acetate, ethinyl estradiol, ferrous fumarate drug combination


alginate, aluminium hydroxide, magnesium trisilicate, sodium bicarbonate drug combination


Artemether, Lumefantrine Drug Combination


3,5-Dimethyl-1-(3-Nitrophenyl)-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester


tyrosyl-valyl-alanyl-aspartic acid fluoromethyl ketone


chlorhexidine gluconate, lidocaine drug combination


Piperacillin, Tazobactam Drug Combination


Interleukin-6 signaling (Homo sapiens)

biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent


Intrinsic Pathway for Apoptosis (Homo sapiens)


Translesion synthesis by REV1 (Homo sapiens)


Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template (Homo sapiens)


Recognition and association of DNA glycosylase with site containing an affected pyrimidine (Homo sapiens)


Cleavage of the damaged pyrimidine  (Homo sapiens)


Recognition and association of DNA glycosylase with site containing an affected purine (Homo sapiens)


Cleavage of the damaged purine (Homo sapiens)


Displacement of DNA glycosylase by APEX1 (Homo sapiens)


POLB-Dependent Long Patch Base Excision Repair (Homo sapiens)


Resolution of AP sites via the multiple-nucleotide patch replacement pathway (Homo sapiens)


Resolution of AP sites via the single-nucleotide replacement pathway (Homo sapiens)


Activation of BIM and translocation to mitochondria  (Homo sapiens)


Activation of BAD and translocation to mitochondria  (Homo sapiens)


Activation of NOXA and translocation to mitochondria (Homo sapiens)


Activation and oligomerization of BAK protein (Homo sapiens)


Release of apoptotic factors from the mitochondria (Homo sapiens)


Activation of caspases through apoptosome-mediated cleavage (Homo sapiens)


Cytochrome c-mediated apoptotic response (Homo sapiens)


SMAC (DIABLO) binds to IAPs  (Homo sapiens)


SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes  (Homo sapiens)


Apoptotic cleavage of cellular proteins (Homo sapiens)


SMAC, XIAP-regulated apoptotic response (Homo sapiens)


Apoptotic factor-mediated response (Homo sapiens)


PKA-mediated phosphorylation of CREB (Homo sapiens)


CaMK IV-mediated phosphorylation of CREB (Homo sapiens)


Calmodulin induced events (Homo sapiens)


G-protein mediated events (Homo sapiens)


Neurotransmitter clearance (Homo sapiens)


Neurotransmitter receptors and postsynaptic signal transmission (Homo sapiens)


Transmission across Chemical Synapses (Homo sapiens)


Formation of RNA Pol II elongation complex  (Homo sapiens)


RAF-independent MAPK1/3 activation (Homo sapiens)


Formation of the Early Elongation Complex (Homo sapiens)


Inhibition of replication initiation of damaged DNA by RB1/E2F1 (Homo sapiens)


E2F-enabled inhibition of pre-replication complex formation (Homo sapiens)


E2F mediated regulation of DNA replication (Homo sapiens)


Activation, translocation and oligomerization of BAX (Homo sapiens)


Activation of BH3-only proteins (Homo sapiens)


Effects of PIP2 hydrolysis (Homo sapiens)


Disinhibition of SNARE formation (Homo sapiens)


GPVI-mediated activation cascade (Homo sapiens)


Downstream signaling events of B Cell Receptor (BCR) (Homo sapiens)


Activation of NF-kappaB in B cells (Homo sapiens)


Activation of RAS in B cells (Homo sapiens)


ISG15 antiviral mechanism (Homo sapiens)


Antiviral mechanism by IFN-stimulated genes (Homo sapiens)


Prolactin receptor signaling (Homo sapiens)


ROS and RNS production in phagocytes (Homo sapiens)


Signaling by FGFR in disease (Homo sapiens)


Regulation of gene expression by Hypoxia-inducible Factor (Homo sapiens)


Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (Homo sapiens)


Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants (Homo sapiens)


Cross-presentation of particulate exogenous antigens (phagosomes) (Homo sapiens)


Cross-presentation of soluble exogenous antigens (endosomes) (Homo sapiens)


Erythrocytes take up carbon dioxide and release oxygen (Homo sapiens)


Methionine salvage pathway (Homo sapiens)


Erythrocytes take up oxygen and release carbon dioxide (Homo sapiens)


SHC1 events in ERBB2 signaling (Homo sapiens)


PI3K events in ERBB4 signaling (Homo sapiens)


SHC1 events in ERBB4 signaling (Homo sapiens)


PLCG1 events in ERBB2 signaling (Homo sapiens)


Nuclear signaling by ERBB4 (Homo sapiens)


Downregulation of ERBB4 signaling (Homo sapiens)


PIP3 activates AKT signaling (Homo sapiens)


Cytokine Signaling in Immune system (Homo sapiens)


Spry regulation of FGF signaling (Homo sapiens)


ATP sensitive Potassium channels (Homo sapiens)


Activation of G protein gated Potassium channels (Homo sapiens)


Ca2+ activated K+ channels (Homo sapiens)


G protein gated Potassium channels (Homo sapiens)


Inwardly rectifying K+ channels (Homo sapiens)


Potassium transport channels (Homo sapiens)


Voltage gated Potassium channels (Homo sapiens)


Tandem pore domain potassium channels (Homo sapiens)


TWIK-releated acid-sensitive K+ channel (TASK) (Homo sapiens)


TWIK related potassium channel (TREK) (Homo sapiens)


GRB7 events in ERBB2 signaling (Homo sapiens)


Downregulation of ERBB2:ERBB3 signaling (Homo sapiens)


Mitochondrial iron-sulfur cluster biogenesis (Homo sapiens)


BMAL1:CLOCK,NPAS2 activates circadian expression (Homo sapiens)


Elevation of cytosolic Ca2+ levels (Homo sapiens)


Activation of PUMA and translocation to mitochondria (Homo sapiens)


Caspase activation via Death Receptors in the presence of ligand (Homo sapiens)


Common Pathway of Fibrin Clot Formation (Homo sapiens)


Formation of Fibrin Clot (Clotting Cascade) (Homo sapiens)


Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB (Homo sapiens)


Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Homo sapiens)


Amplification of signal from the kinetochores (Homo sapiens)


Inactivation of APC/C via direct inhibition of the APC/C complex (Homo sapiens)


Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal (Homo sapiens)


Aerobic respiration and respiratory electron transport (Homo sapiens)


Regulation of KIT signaling (Homo sapiens)


Regulation of signaling by NODAL (Homo sapiens)


Translocation of SLC2A4 (GLUT4) to the plasma membrane (Homo sapiens)


Reversible hydration of carbon dioxide (Homo sapiens)


O2/CO2 exchange in erythrocytes (Homo sapiens)


Phase II - Conjugation of compounds (Homo sapiens)


Fibronectin matrix formation (Homo sapiens)


Polo-like kinase mediated events (Homo sapiens)


L13a-mediated translational silencing of Ceruloplasmin expression (Homo sapiens)


Gap junction trafficking and regulation (Homo sapiens)


Metabolism of nucleotides (Homo sapiens)


Transport of the SLBP independent Mature mRNA (Homo sapiens)


Transport of the SLBP Dependant Mature mRNA (Homo sapiens)


Transport of Mature mRNA Derived from an Intronless Transcript (Homo sapiens)


Transport of Mature mRNAs Derived from Intronless Transcripts (Homo sapiens)


Transport of Mature mRNA derived from an Intron-Containing Transcript (Homo sapiens)


Activation of Matrix Metalloproteinases (Homo sapiens)


Conjugation of carboxylic acids (Homo sapiens)


Gamma-carboxylation of protein precursors (Homo sapiens)


Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus (Homo sapiens)


Gamma-carboxylation, transport, and amino-terminal cleavage of proteins (Homo sapiens)


ZBP1(DAI) mediated induction of type I IFNs (Homo sapiens)


IRF3 mediated activation of type 1 IFN (Homo sapiens)


Sulfide oxidation to sulfate (Homo sapiens)


Cysteine formation from homocysteine (Homo sapiens)


Budding and maturation of HIV virion (Homo sapiens)


Early Phase of HIV Life Cycle (Homo sapiens)


Late Phase of HIV Life Cycle (Homo sapiens)


Host Interactions of HIV factors (Homo sapiens)


PKA-mediated phosphorylation of key metabolic factors (Homo sapiens)


ChREBP activates metabolic gene expression (Homo sapiens)


PP2A-mediated dephosphorylation of key metabolic factors (Homo sapiens)


Heparan sulfate/heparin (HS-GAG) metabolism (Homo sapiens)


Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Homo sapiens)


Signaling by EGFR in Cancer (Homo sapiens)


PKA activation in glucagon signalling (Homo sapiens)


Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters (Homo sapiens)


Nef mediated downregulation of MHC class I complex cell surface expression (Homo sapiens)


Nef and signal transduction (Homo sapiens)


The role of Nef in HIV-1 replication and disease pathogenesis (Homo sapiens)


Rev-mediated nuclear export of HIV RNA (Homo sapiens)


Collagen biosynthesis and modifying enzymes (Homo sapiens)


Inhibition of TSC complex formation by PKB (Homo sapiens)


Toll Like Receptor 4 (TLR4) Cascade (Homo sapiens)


Transfer of LPS from LBP carrier to CD14 (Homo sapiens)


Synthesis of PIPs at the plasma membrane (Homo sapiens)


Synthesis of PIPs at the Golgi membrane (Homo sapiens)


Synthesis of PIPs at the early endosome membrane (Homo sapiens)


Synthesis of PIPs at the late endosome membrane (Homo sapiens)


MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Homo sapiens)


Sphingolipid de novo biosynthesis (Homo sapiens)


MyD88-independent TLR4 cascade  (Homo sapiens)


mTORC1-mediated signalling (Homo sapiens)


The activation of arylsulfatases (Homo sapiens)


Initial triggering of complement (Homo sapiens)


Terminal pathway of complement (Homo sapiens)


Creation of C4 and C2 activators (Homo sapiens)


Formation of HIV elongation complex in the absence of HIV Tat (Homo sapiens)


Formation of the HIV-1 Early Elongation Complex (Homo sapiens)


RNA Pol II CTD phosphorylation and interaction with CE during HIV infection (Homo sapiens)


HIV Transcription Initiation (Homo sapiens)


RNA Polymerase II HIV Promoter Escape (Homo sapiens)


HIV Transcription Elongation (Homo sapiens)


Transcription of the HIV genome (Homo sapiens)


Formation of HIV-1 elongation complex containing HIV-1 Tat (Homo sapiens)


Pausing and recovery of Tat-mediated HIV elongation (Homo sapiens)


Abortive elongation of HIV-1 transcript in the absence of Tat (Homo sapiens)


Tat-mediated HIV elongation arrest and recovery (Homo sapiens)


HIV elongation arrest and recovery (Homo sapiens)


Pausing and recovery of HIV elongation (Homo sapiens)


Nef Mediated CD4 Down-regulation (Homo sapiens)


Trafficking and processing of endosomal TLR (Homo sapiens)


Toll Like Receptor 9 (TLR9) Cascade (Homo sapiens)


Toll Like Receptor 10 (TLR10) Cascade (Homo sapiens)


Toll Like Receptor 3 (TLR3) Cascade (Homo sapiens)


Toll Like Receptor 5 (TLR5) Cascade (Homo sapiens)


Toll Like Receptor TLR1:TLR2 Cascade (Homo sapiens)


Toll Like Receptor 7/8 (TLR7/8) Cascade (Homo sapiens)


Toll Like Receptor TLR6:TLR2 Cascade (Homo sapiens)


Virus Assembly and Release (Homo sapiens)


Transport of Ribonucleoproteins into the Host Nucleus (Homo sapiens)


Influenza Viral RNA Transcription and Replication (Homo sapiens)


Export of Viral Ribonucleoproteins from Nucleus (Homo sapiens)


NS1 Mediated Effects on Host Pathways (Homo sapiens)


Assembly of Viral Components at the Budding Site (Homo sapiens)


Viral Messenger RNA Synthesis (Homo sapiens)


NEP/NS2 Interacts with the Cellular Export Machinery (Homo sapiens)


Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways (Homo sapiens)


Neurotoxicity of clostridium toxins (Homo sapiens)


Toll-like Receptor Cascades (Homo sapiens)


DDX58/IFIH1-mediated induction of interferon-alpha/beta (Homo sapiens)


Prolonged ERK activation events (Homo sapiens)


Adenylate cyclase activating pathway (Homo sapiens)


Adenylate cyclase inhibitory pathway (Homo sapiens)


Signaling by TGF-beta Receptor Complex (Homo sapiens)


Packaging Of Telomere Ends (Homo sapiens)


APC/C:Cdc20 mediated degradation of Cyclin B (Homo sapiens)


Autodegradation of Cdh1 by Cdh1:APC/C (Homo sapiens)


SCF-beta-TrCP mediated degradation of Emi1 (Homo sapiens)


APC/C-mediated degradation of cell cycle proteins (Homo sapiens)


APC/C:Cdc20 mediated degradation of Securin (Homo sapiens)


APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Homo sapiens)


Cdc20:Phospho-APC/C mediated degradation of Cyclin A (Homo sapiens)


Transport and metabolism of PAPS (Homo sapiens)


Glutathione synthesis and recycling (Homo sapiens)


Polymerase switching on the C-strand of the telomere (Homo sapiens)


Processive synthesis on the C-strand of the telomere (Homo sapiens)


Telomere C-strand synthesis initiation (Homo sapiens)


Removal of the Flap Intermediate from the C-strand (Homo sapiens)


Membrane binding and targetting of GAG proteins (Homo sapiens)


Synthesis And Processing Of GAG, GAGPOL Polyproteins (Homo sapiens)


Assembly Of The HIV Virion (Homo sapiens)


Integration of viral DNA into host genomic DNA (Homo sapiens)


Interactions of Vpr with host cellular proteins (Homo sapiens)


Interactions of Tat with host cellular proteins (Homo sapiens)


Activation of ATR in response to replication stress (Homo sapiens)


Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase (Homo sapiens)


Phosphorylation of the APC/C (Homo sapiens)


Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Homo sapiens)


Conjugation of salicylate with glycine (Homo sapiens)


Conjugation of benzoate with glycine (Homo sapiens)


Conjugation of phenylacetate with glutamine (Homo sapiens)


Interactions of Rev with host cellular proteins (Homo sapiens)


Retrograde neurotrophin signalling (Homo sapiens)


Autointegration results in viral DNA circles (Homo sapiens)


Chondroitin sulfate/dermatan sulfate metabolism (Homo sapiens)


APC-Cdc20 mediated degradation of Nek2A (Homo sapiens)


APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint (Homo sapiens)


GRB2 events in EGFR signaling (Homo sapiens)


SHC1 events in EGFR signaling (Homo sapiens)


Vpu mediated degradation of CD4 (Homo sapiens)


Vif-mediated degradation of APOBEC3G (Homo sapiens)


APOBEC3G mediated resistance to HIV-1 infection (Homo sapiens)


Nuclear import of Rev protein (Homo sapiens)


Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization (Homo sapiens)


Vpr-mediated nuclear import of PICs (Homo sapiens)


RIP-mediated NFkB activation via ZBP1 (Homo sapiens)


Serotonin Neurotransmitter Release Cycle (Homo sapiens)


Norepinephrine Neurotransmitter Release Cycle (Homo sapiens)


Acetylcholine binding and downstream events (Homo sapiens)


Toll Like Receptor 2 (TLR2) Cascade (Homo sapiens)


Nef Mediated CD8 Down-regulation (Homo sapiens)


STING mediated induction of host immune responses (Homo sapiens)


Signaling by cytosolic FGFR1 fusion mutants (Homo sapiens)


Signaling by activated point mutants of FGFR1 (Homo sapiens)


FGFR1 mutant receptor activation (Homo sapiens)


FGFR2 mutant receptor activation (Homo sapiens)


Signaling by activated point mutants of FGFR3 (Homo sapiens)


Synthesis of pyrophosphates in the cytosol (Homo sapiens)


Synthesis of IP2, IP, and Ins in the cytosol (Homo sapiens)


Synthesis of IPs in the nucleus (Homo sapiens)


Synthesis of IP3 and IP4 in the cytosol (Homo sapiens)


Downstream signal transduction (Homo sapiens)


Activation of TRKA receptors (Homo sapiens)


Signaling by NTRK1 (TRKA) (Homo sapiens)


SCF(Skp2)-mediated degradation of p27/p21 (Homo sapiens)


Signalling to p38 via RIT and RIN (Homo sapiens)


FGFR3 ligand binding and activation (Homo sapiens)


FGFR2 ligand binding and activation (Homo sapiens)


FGFR1 ligand binding and activation (Homo sapiens)


FGFR4 ligand binding and activation (Homo sapiens)


FGFR1b ligand binding and activation (Homo sapiens)


FGFR3b ligand binding and activation (Homo sapiens)


FGFR3c ligand binding and activation (Homo sapiens)


FGFR1c ligand binding and activation (Homo sapiens)


FGFR1c and Klotho ligand binding and activation (Homo sapiens)


FGFR2c ligand binding and activation (Homo sapiens)


FGFR2b ligand binding and activation (Homo sapiens)


Oligomerization of connexins into connexons (Homo sapiens)


Transport of connexins along the secretory pathway (Homo sapiens)


Transport of connexons to the plasma membrane (Homo sapiens)


Pre-NOTCH Processing in the Endoplasmic Reticulum (Homo sapiens)


Pre-NOTCH Transcription and Translation (Homo sapiens)


Pre-NOTCH Processing in Golgi (Homo sapiens)


Pre-NOTCH Expression and Processing (Homo sapiens)


Regulation of gap junction activity (Homo sapiens)


Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Homo sapiens)


NRAGE signals death through JNK (Homo sapiens)


p75 NTR receptor-mediated signalling (Homo sapiens)


Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Homo sapiens)


Synthesis of bile acids and bile salts via 27-hydroxycholesterol (Homo sapiens)


Neurophilin interactions with VEGF and VEGFR (Homo sapiens)


VEGF ligand-receptor interactions (Homo sapiens)


Metabolism of non-coding RNA (Homo sapiens)


Degradation of beta-catenin by the destruction complex (Homo sapiens)


VEGF binds to VEGFR leading to receptor dimerization (Homo sapiens)


Formation of annular gap junctions (Homo sapiens)


Metabolism of steroid hormones (Homo sapiens)


Beta-catenin phosphorylation cascade (Homo sapiens)


GRB2 events in ERBB2 signaling (Homo sapiens)


PI3K events in ERBB2 signaling (Homo sapiens)


Cobalamin (Cbl, vitamin B12) transport and metabolism (Homo sapiens)


Biotin transport and metabolism (Homo sapiens)


Vitamin B2 (riboflavin) metabolism (Homo sapiens)


Metabolism of vitamins and cofactors (Homo sapiens)


Glycosaminoglycan-protein linkage region biosynthesis (Homo sapiens)


AKT phosphorylates targets in the cytosol (Homo sapiens)


AKT phosphorylates targets in the nucleus (Homo sapiens)


Nuclear Events (kinase and transcription factor activation) (Homo sapiens)


Negative regulation of the PI3K/AKT network (Homo sapiens)


ER to Golgi Anterograde Transport (Homo sapiens)


TCF dependent signaling in response to WNT (Homo sapiens)


WNT mediated activation of DVL (Homo sapiens)


Assembly of collagen fibrils and other multimeric structures (Homo sapiens)


Phosphorylation of CD3 and TCR zeta chains (Homo sapiens)


Translocation of ZAP-70 to Immunological synapse (Homo sapiens)


Generation of second messenger molecules (Homo sapiens)


Fcgamma receptor (FCGR) dependent phagocytosis (Homo sapiens)


Regulation of actin dynamics for phagocytic cup formation (Homo sapiens)


Role of phospholipids in phagocytosis (Homo sapiens)


YAP1- and WWTR1 (TAZ)-stimulated gene expression (Homo sapiens)


FGFR3 mutant receptor activation (Homo sapiens)


Activated point mutants of FGFR2 (Homo sapiens)


NOSTRIN mediated eNOS trafficking (Homo sapiens)


Linoleic acid (LA) metabolism (Homo sapiens)


alpha-linolenic acid (ALA) metabolism (Homo sapiens)


Cell death signalling via NRAGE, NRIF and NADE (Homo sapiens)


NFG and proNGF binds to p75NTR (Homo sapiens)


NADE modulates death signalling (Homo sapiens)


NRIF signals cell death from the nucleus (Homo sapiens)


p75NTR recruits signalling complexes (Homo sapiens)


NF-kB is activated and signals survival (Homo sapiens)


Metabolism of amine-derived hormones (Homo sapiens)


Catecholamine biosynthesis (Homo sapiens)


Peptide hormone biosynthesis (Homo sapiens)


Astrocytic Glutamate-Glutamine Uptake And Metabolism (Homo sapiens)


Glutamate Neurotransmitter Release Cycle (Homo sapiens)


Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells (Homo sapiens)


Regulation of gene expression in beta cells (Homo sapiens)


Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells (Homo sapiens)


Regulation of gene expression in early pancreatic precursor cells (Homo sapiens)


Regulation of activated PAK-2p34 by proteasome mediated degradation (Homo sapiens)


Stimulation of the cell death response by PAK-2p34 (Homo sapiens)


Cytochrome P450 - arranged by substrate type (Homo sapiens)


Phase I - Functionalization of compounds (Homo sapiens)


Sterols are 12-hydroxylated by CYP8B1 (Homo sapiens)


Epigenetic regulation of gene expression (Homo sapiens)


NOTCH1 Intracellular Domain Regulates Transcription (Homo sapiens)


Activated NOTCH1 Transmits Signal to the Nucleus (Homo sapiens)


PRC2 methylates histones and DNA (Homo sapiens)


Dopamine Neurotransmitter Release Cycle (Homo sapiens)


EGFR interacts with phospholipase C-gamma (Homo sapiens)


Molecules associated with elastic fibres (Homo sapiens)


Synthesis of 5-eicosatetraenoic acids (Homo sapiens)


Synthesis of 12-eicosatetraenoic acid derivatives (Homo sapiens)


Synthesis of 15-eicosatetraenoic acid derivatives (Homo sapiens)


Transcriptional activation of mitochondrial biogenesis (Homo sapiens)


Activation of PPARGC1A (PGC-1alpha) by phosphorylation (Homo sapiens)


Integrin cell surface interactions (Homo sapiens)


Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Homo sapiens)


Scavenging of heme from plasma (Homo sapiens)


FMO oxidises nucleophiles (Homo sapiens)


Binding and Uptake of Ligands by Scavenger Receptors (Homo sapiens)


TGF-beta receptor signaling activates SMADs (Homo sapiens)


TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) (Homo sapiens)


Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Homo sapiens)


Downregulation of SMAD2/3:SMAD4 transcriptional activity (Homo sapiens)


SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription (Homo sapiens)


EGFR Transactivation by Gastrin (Homo sapiens)


The retinoid cycle in cones (daylight vision) (Homo sapiens)


NOTCH2 intracellular domain regulates transcription (Homo sapiens)


Anchoring fibril formation (Homo sapiens)


PI3K/AKT Signaling in Cancer (Homo sapiens)


Constitutive Signaling by Aberrant PI3K in Cancer (Homo sapiens)


Crosslinking of collagen fibrils (Homo sapiens)


Condensation of Prophase Chromosomes (Homo sapiens)


Phosphate bond hydrolysis by NUDT proteins (Homo sapiens)


Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Homo sapiens)


Metabolism of ingested SeMet, Sec, MeSec into H2Se (Homo sapiens)


Metabolism of ingested H2SeO4 and H2SeO3 into H2Se (Homo sapiens)


Activation of gene expression by SREBF (SREBP) (Homo sapiens)


IRS-related events triggered by IGF1R (Homo sapiens)


SHC-related events triggered by IGF1R (Homo sapiens)


Retinoid cycle disease events (Homo sapiens)


The canonical retinoid cycle in rods (twilight vision) (Homo sapiens)


Fc epsilon receptor (FCERI) signaling (Homo sapiens)


MASTL Facilitates Mitotic Progression (Homo sapiens)


Cohesin Loading onto Chromatin (Homo sapiens)


Antagonism of Activin by Follistatin (Homo sapiens)


Diseases associated with visual transduction (Homo sapiens)


Activation of the phototransduction cascade (Homo sapiens)


Condensation of Prometaphase Chromosomes (Homo sapiens)


The phototransduction cascade (Homo sapiens)


Mitotic Metaphase and Anaphase (Homo sapiens)


Oxidative Stress Induced Senescence (Homo sapiens)


Senescence-Associated Secretory Phenotype (SASP) (Homo sapiens)


Formation of Senescence-Associated Heterochromatin Foci (SAHF) (Homo sapiens)


Oncogene Induced Senescence (Homo sapiens)


DNA Damage/Telomere Stress Induced Senescence (Homo sapiens)


TRIF-mediated programmed cell death (Homo sapiens)


Cytosolic iron-sulfur cluster assembly (Homo sapiens)


Regulation of PLK1 Activity at G2/M Transition (Homo sapiens)


Signaling by NOTCH1 PEST Domain Mutants in Cancer (Homo sapiens)


Signaling by NOTCH1 in Cancer (Homo sapiens)


FBXW7 Mutants and NOTCH1 in Cancer (Homo sapiens)


Constitutive Signaling by NOTCH1 PEST Domain Mutants (Homo sapiens)


Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling (Homo sapiens)


Acetylcholine Neurotransmitter Release Cycle (Homo sapiens)


Caspase-mediated cleavage of cytoskeletal proteins (Homo sapiens)


Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant (Homo sapiens)


Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant (Homo sapiens)


Signaling by NOTCH1 HD Domain Mutants in Cancer (Homo sapiens)


Constitutive Signaling by NOTCH1 HD Domain Mutants (Homo sapiens)


Role of LAT2/NTAL/LAB on calcium mobilization (Homo sapiens)


Ficolins bind to repetitive carbohydrate structures on the target cell surface (Homo sapiens)


FCERI mediated MAPK activation (Homo sapiens)


FCERI mediated Ca+2 mobilization (Homo sapiens)


FCERI mediated NF-kB activation (Homo sapiens)


POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation (Homo sapiens)


POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation (Homo sapiens)


Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer (Homo sapiens)


Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants (Homo sapiens)


NOTCH2 Activation and Transmission of Signal to the Nucleus (Homo sapiens)


Activation of NIMA Kinases NEK9, NEK6, NEK7 (Homo sapiens)


Initiation of Nuclear Envelope (NE) Reformation (Homo sapiens)


Non-integrin membrane-ECM interactions (Homo sapiens)


Scavenging by Class B Receptors (Homo sapiens)


Scavenging by Class A Receptors (Homo sapiens)


Scavenging by Class F Receptors (Homo sapiens)


SUMO is conjugated to E1 (UBA2:SAE1) (Homo sapiens)


SUMO is transferred from E1 to E2 (UBE2I, UBC9) (Homo sapiens)


SUMO is proteolytically processed (Homo sapiens)


SUMOylation of DNA damage response and repair proteins (Homo sapiens)


SUMO E3 ligases SUMOylate target proteins (Homo sapiens)


DEx/H-box helicases activate type I IFN and inflammatory cytokines production  (Homo sapiens)


LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production (Homo sapiens)


HDACs deacetylate histones (Homo sapiens)


PKMTs methylate histone lysines (Homo sapiens)


HDMs demethylate histones (Homo sapiens)


RMTs methylate histone arginines (Homo sapiens)


Processing and activation of SUMO (Homo sapiens)


Glycogen storage diseases (Homo sapiens)


SUMOylation of transcription factors (Homo sapiens)


WNT ligand biogenesis and trafficking (Homo sapiens)


Chromatin modifying enzymes (Homo sapiens)


STAT6-mediated induction of chemokines (Homo sapiens)


IRF3-mediated induction of type I IFN (Homo sapiens)


Hydroxycarboxylic acid-binding receptors (Homo sapiens)


Defects in cobalamin (B12) metabolism (Homo sapiens)


Defects in vitamin and cofactor metabolism (Homo sapiens)


Detoxification of Reactive Oxygen Species (Homo sapiens)


Nuclear Pore Complex (NPC) Disassembly (Homo sapiens)


Loss of Function of SMAD4 in Cancer (Homo sapiens)


Loss of Function of SMAD2/3 in Cancer (Homo sapiens)


Signaling by TGF-beta Receptor Complex in Cancer (Homo sapiens)


SMAD2/3 Phosphorylation Motif Mutants in Cancer (Homo sapiens)


SMAD4 MH2 Domain Mutants in Cancer (Homo sapiens)


SMAD2/3 MH2 Domain Mutants in Cancer (Homo sapiens)


Defects in biotin (Btn) metabolism (Homo sapiens)


Defective MTRR causes HMAE (Homo sapiens)


Defective MTR causes HMAG (Homo sapiens)


Regulation of HSF1-mediated heat shock response (Homo sapiens)


HSF1-dependent transactivation (Homo sapiens)


Defective HLCS causes multiple carboxylase deficiency (Homo sapiens)


Autodegradation of the E3 ubiquitin ligase COP1 (Homo sapiens)


Notch-HLH transcription pathway (Homo sapiens)


Apoptotic cleavage of cell adhesion  proteins (Homo sapiens)


Breakdown of the nuclear lamina (Homo sapiens)


GRB2:SOS provides linkage to MAPK signaling for Integrins  (Homo sapiens)


Diseases associated with glycosaminoglycan metabolism (Homo sapiens)


Defective B4GALT7 causes EDS, progeroid type (Homo sapiens)


Defective B3GAT3 causes JDSSDHD (Homo sapiens)


Defective CHST3 causes SEDCJD (Homo sapiens)


Defective CHST14 causes EDS, musculocontractural type (Homo sapiens)


Defective CHSY1 causes TPBS (Homo sapiens)


Loss of Function of TGFBR2 in Cancer (Homo sapiens)


TGFBR2 MSI Frameshift Mutants in Cancer (Homo sapiens)


TGFBR2 Kinase Domain Mutants in Cancer (Homo sapiens)


Defective CHST6 causes MCDC1 (Homo sapiens)


Defective EXT2 causes exostoses 2 (Homo sapiens)


Defective ST3GAL3 causes MCT12 and EIEE15 (Homo sapiens)


Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) (Homo sapiens)


Defective EXT1 causes exostoses 1, TRPS2 and CHDS (Homo sapiens)


TGFBR1 KD Mutants in Cancer (Homo sapiens)


Loss of Function of TGFBR1 in Cancer (Homo sapiens)


TGFBR1 LBD Mutants in Cancer (Homo sapiens)


Transcriptional Regulation by TP53 (Homo sapiens)


p130Cas linkage to MAPK signaling for integrins (Homo sapiens)


Class A/1 (Rhodopsin-like receptors) (Homo sapiens)


Class B/2 (Secretin family receptors) (Homo sapiens)


Nephrin family interactions (Homo sapiens)


NCAM signaling for neurite out-growth (Homo sapiens)


Peptide ligand-binding receptors (Homo sapiens)


Amine ligand-binding receptors (Homo sapiens)


Hormone ligand-binding receptors (Homo sapiens)


Signaling by ROBO receptors (Homo sapiens)


Deactivation of the beta-catenin transactivating complex (Homo sapiens)


Negative regulation of TCF-dependent signaling by WNT ligand antagonists (Homo sapiens)


Diseases of glycosylation (Homo sapiens)


Myoclonic epilepsy of Lafora (Homo sapiens)


Enzymatic degradation of dopamine by COMT (Homo sapiens)


Enzymatic degradation of Dopamine by monoamine oxidase (Homo sapiens)


Dopamine clearance from the synaptic cleft (Homo sapiens)


Cytosolic tRNA aminoacylation (Homo sapiens)


Mitochondrial tRNA aminoacylation (Homo sapiens)


Tachykinin receptors bind tachykinins (Homo sapiens)


Chemokine receptors bind chemokines (Homo sapiens)


Loss of Nlp from mitotic centrosomes (Homo sapiens)


Recruitment of mitotic centrosome proteins and complexes (Homo sapiens)


Loss of proteins required for interphase microtubule organization from the centrosome (Homo sapiens)


Serotonin clearance from the synaptic cleft (Homo sapiens)


Energy dependent regulation of mTOR by LKB1-AMPK (Homo sapiens)


ATF4 activates genes in response to endoplasmic reticulum  stress (Homo sapiens)


ATF6 (ATF6-alpha) activates chaperones (Homo sapiens)


XBP1(S) activates chaperone genes (Homo sapiens)


PERK regulates gene expression (Homo sapiens)


IRE1alpha activates chaperones (Homo sapiens)


Unfolded Protein Response (UPR) (Homo sapiens)


ATF6 (ATF6-alpha) activates chaperone genes (Homo sapiens)


Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) (Homo sapiens)


Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Homo sapiens)


Olfactory Signaling Pathway (Homo sapiens)


ABC-family proteins mediated transport (Homo sapiens)


Nuclear Receptor transcription pathway (Homo sapiens)


Beta-catenin independent WNT signaling (Homo sapiens)


GPCR downstream signalling (Homo sapiens)


Vasopressin-like receptors (Homo sapiens)


CD28 dependent PI3K/Akt signaling (Homo sapiens)


CD28 dependent Vav1 pathway (Homo sapiens)


Orexin and neuropeptides FF and QRFP bind to their respective receptors (Homo sapiens)


Alpha-oxidation of phytanate (Homo sapiens)


Beta-oxidation of pristanoyl-CoA (Homo sapiens)


Prefoldin mediated transfer of substrate  to CCT/TriC (Homo sapiens)


Cooperation of Prefoldin and TriC/CCT  in actin and tubulin folding (Homo sapiens)


Formation of tubulin folding intermediates by CCT/TriC (Homo sapiens)


Beta-oxidation of very long chain fatty acids (Homo sapiens)


Folding of actin by CCT/TriC (Homo sapiens)


Chaperonin-mediated protein folding (Homo sapiens)


Association of TriC/CCT with target proteins during biosynthesis (Homo sapiens)


Muscarinic acetylcholine receptors (Homo sapiens)


Diseases associated with O-glycosylation of proteins (Homo sapiens)


Peroxisomal lipid metabolism (Homo sapiens)


Signal regulatory protein family interactions (Homo sapiens)


Eicosanoid ligand-binding receptors (Homo sapiens)


Prostanoid ligand receptors (Homo sapiens)


Adrenaline signalling through Alpha-2 adrenergic receptor (Homo sapiens)


Nitric oxide stimulates guanylate cyclase (Homo sapiens)


ADP signalling through P2Y purinoceptor 12 (Homo sapiens)


G beta:gamma signalling through PI3Kgamma (Homo sapiens)


Prostacyclin signalling through prostacyclin receptor (Homo sapiens)


EPHB-mediated forward signaling (Homo sapiens)


EPHA-mediated growth cone collapse (Homo sapiens)


EPH-ephrin mediated repulsion of cells (Homo sapiens)


G-protein beta:gamma signalling (Homo sapiens)


Activation of AMPA receptors (Homo sapiens)


Trafficking of AMPA receptors (Homo sapiens)


Glutamate binding, activation of AMPA receptors and synaptic plasticity (Homo sapiens)


Sema3A PAK dependent Axon repulsion (Homo sapiens)


SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion (Homo sapiens)


CRMPs in Sema3A signaling (Homo sapiens)


Regulation of lipid metabolism by PPARalpha (Homo sapiens)


Free fatty acids regulate insulin secretion (Homo sapiens)


Incretin synthesis, secretion, and inactivation (Homo sapiens)


Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) (Homo sapiens)


Sema4D in semaphorin signaling (Homo sapiens)


G alpha (q) signalling events (Homo sapiens)


G alpha (12/13) signalling events (Homo sapiens)


Sema4D mediated inhibition of cell attachment and migration (Homo sapiens)


Sema4D induced cell migration and growth-cone collapse (Homo sapiens)


Other semaphorin interactions (Homo sapiens)


Trafficking of GluR2-containing AMPA receptors (Homo sapiens)


Nucleotide-like (purinergic) receptors (Homo sapiens)


G beta:gamma signalling through PLC beta (Homo sapiens)


Reduction of cytosolic Ca++ levels (Homo sapiens)


Platelet calcium homeostasis (Homo sapiens)


G alpha (s) signalling events (Homo sapiens)


ADP signalling through P2Y purinoceptor 1 (Homo sapiens)


G alpha (i) signalling events (Homo sapiens)


G alpha (z) signalling events (Homo sapiens)


DCC mediated attractive signaling (Homo sapiens)


Netrin mediated repulsion signals (Homo sapiens)


Caspase activation via Dependence Receptors in the absence of ligand (Homo sapiens)


Role of second messengers in netrin-1 signaling (Homo sapiens)


Lysosphingolipid and LPA receptors (Homo sapiens)


Calcitonin-like ligand receptors (Homo sapiens)


Glucagon-type ligand receptors (Homo sapiens)


Class C/3 (Metabotropic glutamate/pheromone receptors) (Homo sapiens)


Nectin/Necl  trans heterodimerization (Homo sapiens)


Synthesis, secretion, and deacylation of Ghrelin (Homo sapiens)


Transport of bile salts and organic acids, metal ions and amine compounds (Homo sapiens)


Transport of vitamins, nucleosides, and related molecules (Homo sapiens)


SLC-mediated transmembrane transport (Homo sapiens)


Metal ion SLC transporters (Homo sapiens)


Sodium/Calcium exchangers (Homo sapiens)


Arachidonate production from DAG (Homo sapiens)


Cation-coupled Chloride cotransporters (Homo sapiens)


Post-transcriptional silencing by small RNAs (Homo sapiens)


SIRT1 negatively regulates rRNA expression (Homo sapiens)


ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression (Homo sapiens)


NoRC negatively regulates rRNA expression (Homo sapiens)


Type II Na+/Pi cotransporters (Homo sapiens)


Multifunctional anion exchangers (Homo sapiens)


Sodium-coupled phosphate cotransporters (Homo sapiens)


Proton/oligopeptide cotransporters (Homo sapiens)


Regulation of commissural axon pathfinding by SLIT and ROBO (Homo sapiens)


Inactivation of CDC42 and RAC1 (Homo sapiens)


Organic anion transporters (Homo sapiens)


Role of ABL in ROBO-SLIT signaling (Homo sapiens)


Thromboxane signalling through TP receptor (Homo sapiens)


mRNA decay by 3' to 5' exoribonuclease (Homo sapiens)


mRNA decay by 5' to 3' exoribonuclease (Homo sapiens)


GP1b-IX-V activation signalling (Homo sapiens)


Passive transport by Aquaporins (Homo sapiens)


Platelet sensitization by LDL (Homo sapiens)


Lysosome Vesicle Biogenesis (Homo sapiens)


Golgi Associated Vesicle Biogenesis (Homo sapiens)


Sodium-coupled sulphate, di- and tri-carboxylate transporters (Homo sapiens)


Proton-coupled monocarboxylate transport (Homo sapiens)


Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (Homo sapiens)


Zinc efflux and compartmentalization by the SLC30 family (Homo sapiens)


Post NMDA receptor activation events (Homo sapiens)


Binding of TCF/LEF:CTNNB1 to target gene promoters (Homo sapiens)


Depolymerization of the Nuclear Lamina (Homo sapiens)


Defective B3GALT6 causes EDSP2 and SEMDJL1 (Homo sapiens)


Zinc influx into cells by the SLC39 gene family (Homo sapiens)


Na+/Cl- dependent neurotransmitter transporters (Homo sapiens)


CREB1 phosphorylation through the activation of Adenylate Cyclase (Homo sapiens)


CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde (Homo sapiens)


CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling (Homo sapiens)


Activation of NMDA receptors and postsynaptic events (Homo sapiens)


Ras activation upon Ca2+ influx through NMDA receptor (Homo sapiens)


Free fatty acid receptors (Homo sapiens)


Rhesus glycoproteins mediate ammonium transport (Homo sapiens)


Formyl peptide receptors bind formyl peptides and many other ligands (Homo sapiens)


Interaction between L1 and Ankyrins (Homo sapiens)


Signal transduction by L1 (Homo sapiens)


Smooth Muscle Contraction (Homo sapiens)


TAK1-dependent IKK and NF-kappa-B activation   (Homo sapiens)


Asparagine N-linked glycosylation (Homo sapiens)


Synthesis of UDP-N-acetyl-glucosamine (Homo sapiens)


Synthesis of substrates in N-glycan biosythesis (Homo sapiens)


Localization of the PINCH-ILK-PARVIN complex to focal adhesions (Homo sapiens)


Cell-extracellular matrix interactions (Homo sapiens)


Regulation of cytoskeletal remodeling and cell spreading by IPP complex components (Homo sapiens)


Interleukin-1 family signaling (Homo sapiens)


Interleukin-12 family signaling (Homo sapiens)


Signaling by Interleukins (Homo sapiens)


MAPK targets/ Nuclear events mediated by MAP kinases (Homo sapiens)


activated TAK1 mediates p38 MAPK activation (Homo sapiens)


JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1 (Homo sapiens)


Activation of the AP-1 family of transcription factors (Homo sapiens)


Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA (Homo sapiens)


AUF1 (hnRNP D0) binds and destabilizes mRNA (Homo sapiens)


Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA (Homo sapiens)


HuR (ELAVL1) binds and stabilizes mRNA (Homo sapiens)


Regulation of mRNA stability by proteins that bind AU-rich elements (Homo sapiens)


KSRP (KHSRP) binds and destabilizes mRNA (Homo sapiens)


Ionotropic activity of kainate receptors (Homo sapiens)


Activation of Na-permeable kainate receptors (Homo sapiens)


Activation of Ca-permeable Kainate Receptor (Homo sapiens)


Activation of kainate receptors upon glutamate binding (Homo sapiens)


Interleukin-2 family signaling (Homo sapiens)


Regulation of mitotic cell cycle (Homo sapiens)


Mitotic G1 phase and G1/S transition (Homo sapiens)


Thrombin signalling through proteinase activated receptors (PARs) (Homo sapiens)


SUMOylation of RNA binding proteins (Homo sapiens)


Asymmetric localization of PCP proteins (Homo sapiens)


SUMOylation of DNA replication proteins (Homo sapiens)


Disassembly of the destruction complex and recruitment of AXIN to the membrane (Homo sapiens)


Regulation of FZD by ubiquitination (Homo sapiens)


Repression of WNT target genes (Homo sapiens)


Signaling by WNT in cancer (Homo sapiens)


Signaling by AXIN mutants (Homo sapiens)


Signaling by CTNNB1 phospho-site mutants (Homo sapiens)


Signaling by AMER1 mutants (Homo sapiens)


Presynaptic function of Kainate receptors (Homo sapiens)


Defective GALNT3 causes HFTC (Homo sapiens)


Defective LFNG causes SCDO3 (Homo sapiens)


Defective C1GALT1C1 causes TNPS (Homo sapiens)


Defective B3GALTL causes PpS (Homo sapiens)


Defective GALNT12 causes CRCS1 (Homo sapiens)


WNT5A-dependent internalization of FZD4 (Homo sapiens)


Interleukin-3, Interleukin-5 and GM-CSF signaling (Homo sapiens)


WNT5A-dependent internalization of FZD2, FZD5 and ROR2 (Homo sapiens)


PINK1-PRKN Mediated Mitophagy (Homo sapiens)


Uptake and function of anthrax toxins (Homo sapiens)


CASP8 activity is inhibited (Homo sapiens)


VEGFR2 mediated vascular permeability (Homo sapiens)


VEGFR2 mediated cell proliferation (Homo sapiens)


Miscellaneous transport and binding events (Homo sapiens)


B-WICH complex positively regulates rRNA expression (Homo sapiens)


Negative epigenetic regulation of rRNA expression (Homo sapiens)


Toxicity of botulinum toxin type D (botD) (Homo sapiens)


Toxicity of botulinum toxin type B (botB) (Homo sapiens)


Toxicity of botulinum toxin type A (botA) (Homo sapiens)


Toxicity of botulinum toxin type C (botC) (Homo sapiens)


Toxicity of botulinum toxin type F (botF) (Homo sapiens)


Toxicity of botulinum toxin type G (botG) (Homo sapiens)


Toxicity of botulinum toxin type E (botE) (Homo sapiens)


Diseases of Immune System (Homo sapiens)


N-glycan trimming in the ER and Calnexin/Calreticulin cycle (Homo sapiens)


Uptake and function of diphtheria toxin (Homo sapiens)


Uptake and actions of bacterial toxins (Homo sapiens)


Signaling by TCF7L2 mutants (Homo sapiens)


Signaling by GSK3beta mutants (Homo sapiens)


Signaling by LRP5 mutants  (Homo sapiens)


Signaling by RNF43 mutants (Homo sapiens)


Caspase activation via extrinsic apoptotic signalling pathway (Homo sapiens)


TNFR1-induced NF-kappa-B signaling pathway (Homo sapiens)


Hedgehog ligand biogenesis (Homo sapiens)


Synthesis of diphthamide-EEF2 (Homo sapiens)


Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) (Homo sapiens)


Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) (Homo sapiens)


CTNNB1 S33 mutants aren't phosphorylated (Homo sapiens)


CTNNB1 S37 mutants aren't phosphorylated (Homo sapiens)


CTNNB1 S45 mutants aren't phosphorylated (Homo sapiens)


CTNNB1 T41 mutants aren't phosphorylated (Homo sapiens)


Signaling by Retinoic Acid (Homo sapiens)


Hh mutants are degraded by ERAD (Homo sapiens)


Release of Hh-Np from the secreting cell (Homo sapiens)


Negative regulation of TCF-dependent signaling by DVL-interacting proteins (Homo sapiens)


Hh mutants abrogate ligand secretion (Homo sapiens)


APC truncation mutants have impaired AXIN binding (Homo sapiens)


AXIN missense mutants destabilize the destruction complex (Homo sapiens)


Truncations of AMER1 destabilize the destruction complex (Homo sapiens)


Organic cation/anion/zwitterion transport (Homo sapiens)


Phase 4 - resting membrane potential (Homo sapiens)


Phase 3 - rapid repolarisation (Homo sapiens)


Phase 0 - rapid depolarisation (Homo sapiens)


Phase 1 - inactivation of fast Na+ channels (Homo sapiens)


Defective CYP11A1 causes AICSR (Homo sapiens)


Metabolic disorders of biological oxidation enzymes (Homo sapiens)


Defective ACTH causes obesity and POMCD (Homo sapiens)


Diseases associated with the TLR signaling cascade (Homo sapiens)


MyD88 deficiency (TLR2/4) (Homo sapiens)


IKBKB deficiency causes SCID (Homo sapiens)


IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) (Homo sapiens)


IkBA variant leads to EDA-ID (Homo sapiens)


IRAK4 deficiency (TLR2/4) (Homo sapiens)


Dectin-1 mediated noncanonical NF-kB signaling (Homo sapiens)


CLEC7A (Dectin-1) induces NFAT activation (Homo sapiens)


CLEC7A (Dectin-1) signaling (Homo sapiens)


Degradation of GLI1 by the proteasome (Homo sapiens)


Degradation of GLI2 by the proteasome (Homo sapiens)


GLI3 is processed to GLI3R by the proteasome (Homo sapiens)


Activation of anterior HOX genes in hindbrain development during early embryogenesis (Homo sapiens)


ABC transporter disorders (Homo sapiens)


Defective AVP does not bind AVPR1A,B and causes neurohypophyseal diabetes insipidus (NDI) (Homo sapiens)


SLC transporter disorders (Homo sapiens)


Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) (Homo sapiens)


Disorders of transmembrane transporters (Homo sapiens)


Activation of HOX genes during differentiation (Homo sapiens)


VxPx cargo-targeting to cilium (Homo sapiens)


Cargo trafficking to the periciliary membrane (Homo sapiens)


BBSome-mediated cargo-targeting to cilium (Homo sapiens)


C-type lectin receptors (CLRs) (Homo sapiens)


CD209 (DC-SIGN) signaling (Homo sapiens)


RHO GTPases activate PKNs (Homo sapiens)


RHO GTPases activate KTN1 (Homo sapiens)


RHO GTPases activate IQGAPs (Homo sapiens)


RHO GTPases regulate CFTR trafficking (Homo sapiens)


RHO GTPases Activate ROCKs (Homo sapiens)


RHO GTPases activate PAKs (Homo sapiens)


TP53 Regulates Metabolic Genes (Homo sapiens)


Ligand-receptor interactions (Homo sapiens)


TP53 Regulates Transcription of Cell Death Genes (Homo sapiens)


GLI proteins bind promoters of Hh responsive genes to promote transcription (Homo sapiens)


Constitutive Signaling by EGFRvIII (Homo sapiens)


Signaling by EGFRvIII in Cancer (Homo sapiens)


Signaling by Ligand-Responsive EGFR Variants in Cancer (Homo sapiens)


Signaling by Overexpressed Wild-Type EGFR in Cancer (Homo sapiens)


Inhibition of Signaling by Overexpressed EGFR (Homo sapiens)


APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway (Homo sapiens)


PCNA-Dependent Long Patch Base Excision Repair (Homo sapiens)


Vesicle-mediated transport (Homo sapiens)


Phospholipase C-mediated cascade: FGFR1 (Homo sapiens)


Phospholipase C-mediated cascade; FGFR2 (Homo sapiens)


Phospholipase C-mediated cascade; FGFR3 (Homo sapiens)


Phospholipase C-mediated cascade; FGFR4 (Homo sapiens)


Downstream signaling of activated FGFR1 (Homo sapiens)


SHC-mediated cascade:FGFR1 (Homo sapiens)


FRS-mediated FGFR1 signaling (Homo sapiens)


Downstream signaling of activated FGFR2 (Homo sapiens)


SHC-mediated cascade:FGFR2 (Homo sapiens)


FRS-mediated FGFR2 signaling (Homo sapiens)


SHC-mediated cascade:FGFR3 (Homo sapiens)


FRS-mediated FGFR3 signaling (Homo sapiens)


Downstream signaling of activated FGFR3 (Homo sapiens)


FRS-mediated FGFR4 signaling (Homo sapiens)


Downstream signaling of activated FGFR4 (Homo sapiens)


SHC-mediated cascade:FGFR4 (Homo sapiens)


Negative regulation of FGFR1 signaling (Homo sapiens)


Negative regulation of FGFR2 signaling (Homo sapiens)


Negative regulation of FGFR3 signaling (Homo sapiens)


Negative regulation of FGFR4 signaling (Homo sapiens)


Signaling by FGFR2 in disease (Homo sapiens)


Signaling by FGFR4 in disease (Homo sapiens)


Signaling by FGFR1 in disease (Homo sapiens)


Signaling by FGFR3 in disease (Homo sapiens)


Translesion synthesis by POLK (Homo sapiens)


Translesion synthesis by POLI (Homo sapiens)


Termination of translesion DNA synthesis (Homo sapiens)


HHAT G278V doesn't palmitoylate Hh-Np (Homo sapiens)


Regulation of RAS by GAPs (Homo sapiens)


FGFRL1 modulation of FGFR1 signaling (Homo sapiens)


CLEC7A/inflammasome pathway (Homo sapiens)


Metallothioneins bind metals (Homo sapiens)


Diseases of carbohydrate metabolism (Homo sapiens)


Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)


RHO GTPases Activate WASPs and WAVEs (Homo sapiens)


RHO GTPases Activate Formins (Homo sapiens)


RHO GTPases Activate Rhotekin and Rhophilins (Homo sapiens)


TNFR2 non-canonical NF-kB pathway (Homo sapiens)


RHO GTPases Activate NADPH Oxidases (Homo sapiens)


TNFs bind their physiological receptors (Homo sapiens)


MAP2K and MAPK activation (Homo sapiens)


Constitutive Signaling by AKT1 E17K in Cancer (Homo sapiens)


Negative feedback regulation of MAPK pathway (Homo sapiens)


Negative regulation of MAPK pathway (Homo sapiens)


NIK-->noncanonical NF-kB signaling (Homo sapiens)


TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway (Homo sapiens)


Defective CFTR causes cystic fibrosis (Homo sapiens)


MAPK family signaling cascades (Homo sapiens)


Defective ABCC8 can cause hypo- and hyper-glycemias (Homo sapiens)


Defective ABCA3 causes SMDP3 (Homo sapiens)


MAP3K8 (TPL2)-dependent MAPK1/3 activation (Homo sapiens)


HDR through Single Strand Annealing (SSA) (Homo sapiens)


HDR through MMEJ (alt-NHEJ) (Homo sapiens)


HDR through Homologous Recombination (HRR) (Homo sapiens)


Regulation of TLR by endogenous ligand (Homo sapiens)


Diseases associated with surfactant metabolism (Homo sapiens)


Defective pro-SFTPC causes SMDP2 and RDS (Homo sapiens)


Defective CSF2RB causes SMDP5 (Homo sapiens)


Defective CSF2RA causes SMDP4 (Homo sapiens)


Ub-specific processing proteases (Homo sapiens)


Ovarian tumor domain proteases (Homo sapiens)


CD22 mediated BCR regulation (Homo sapiens)


Resolution of D-Loop Structures (Homo sapiens)


Sensing of DNA Double Strand Breaks (Homo sapiens)


Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks (Homo sapiens)


HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Homo sapiens)


Resolution of D-loop Structures through Holliday Junction Intermediates (Homo sapiens)


Homologous DNA Pairing and Strand Exchange (Homo sapiens)


DNA Double Strand Break Response (Homo sapiens)


Processing of DNA double-strand break ends (Homo sapiens)


Presynaptic phase of homologous DNA pairing and strand exchange (Homo sapiens)


Cargo concentration in the ER (Homo sapiens)


Formation of Incision Complex in GG-NER (Homo sapiens)


Nucleotide Excision Repair (Homo sapiens)


Post-translational protein modification (Homo sapiens)


Respiratory electron transport (Homo sapiens)


Presynaptic nicotinic acetylcholine receptors (Homo sapiens)


Postsynaptic nicotinic acetylcholine receptors (Homo sapiens)


Highly sodium permeable postsynaptic acetylcholine nicotinic receptors (Homo sapiens)


Highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Homo sapiens)


Highly calcium permeable nicotinic acetylcholine receptors (Homo sapiens)


RNA Polymerase II Pre-transcription Events (Homo sapiens)


Formation of TC-NER Pre-Incision Complex (Homo sapiens)


Gap-filling DNA repair synthesis and ligation in TC-NER (Homo sapiens)


Interleukin-6 family signaling (Homo sapiens)


tRNA processing in the nucleus (Homo sapiens)


Interleukin-4 and Interleukin-13 signaling (Homo sapiens)


IL-6-type cytokine receptor ligand interactions (Homo sapiens)


rRNA modification in the nucleus and cytosol (Homo sapiens)


Major pathway of rRNA processing in the nucleolus and cytosol (Homo sapiens)


TP53 Regulates Transcription of Cell Cycle Genes (Homo sapiens)


rRNA modification in the mitochondrion (Homo sapiens)


Neurexins and neuroligins (Homo sapiens)


Protein-protein interactions at synapses (Homo sapiens)


TP53 Regulates Transcription of DNA Repair Genes (Homo sapiens)


Metal sequestration by antimicrobial proteins (Homo sapiens)


Signaling by moderate kinase activity BRAF mutants (Homo sapiens)


Signaling by high-kinase activity BRAF mutants (Homo sapiens)


Signaling by BRAF and RAF1 fusions (Homo sapiens)


RAS signaling downstream of NF1 loss-of-function variants (Homo sapiens)


Paradoxical activation of RAF signaling by kinase inactive BRAF (Homo sapiens)


TP53 Regulates Transcription of Genes Involved in Cytochrome C Release (Homo sapiens)


TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain (Homo sapiens)


TP53 Regulates Transcription of Caspase Activators and Caspases (Homo sapiens)


TP53 Regulates Transcription of Death Receptors and Ligands (Homo sapiens)


FGFR2 alternative splicing (Homo sapiens)


Ion influx/efflux at host-pathogen interface (Homo sapiens)


TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest (Homo sapiens)


TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain (Homo sapiens)


TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest (Homo sapiens)


Regulation of TP53 Expression (Homo sapiens)


Regulation of TP53 Activity through Phosphorylation (Homo sapiens)


Regulation of TP53 Degradation (Homo sapiens)


Regulation of TP53 Activity through Acetylation (Homo sapiens)


Regulation of TP53 Activity through Association with Co-factors (Homo sapiens)


Regulation of TP53 Activity through Methylation (Homo sapiens)


Regulation of TP53 Expression and Degradation (Homo sapiens)


Negative regulation of MET activity (Homo sapiens)


Cholesterol biosynthesis via desmosterol (Homo sapiens)


Cholesterol biosynthesis via lathosterol (Homo sapiens)


COPI-mediated anterograde transport (Homo sapiens)


COPI-independent Golgi-to-ER retrograde traffic (Homo sapiens)


Retrograde transport at the Trans-Golgi-Network (Homo sapiens)


Intra-Golgi and retrograde Golgi-to-ER traffic (Homo sapiens)


PI5P Regulates TP53 Acetylation (Homo sapiens)


Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding (Homo sapiens)


Assembly of the ORC complex at the origin of replication (Homo sapiens)


CDC6 association with the ORC:origin complex (Homo sapiens)


Orc1 removal from chromatin (Homo sapiens)


DNA replication initiation (Homo sapiens)


Activation of the pre-replicative complex (Homo sapiens)


DNA Replication Pre-Initiation (Homo sapiens)


CDK-mediated phosphorylation and removal of Cdc6 (Homo sapiens)


Switching of origins to a post-replicative state (Homo sapiens)


Removal of the Flap Intermediate (Homo sapiens)


Processive synthesis on the lagging strand (Homo sapiens)


Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes (Homo sapiens)


Cyclin E associated events during G1/S transition  (Homo sapiens)


G1/S-Specific Transcription (Homo sapiens)


Cyclin D associated events in G1 (Homo sapiens)


Cyclin A/B1/B2 associated events during G2/M transition (Homo sapiens)


Dimerization of procaspase-8 (Homo sapiens)


G2/M DNA damage checkpoint (Homo sapiens)


G2/M DNA replication checkpoint (Homo sapiens)


Transcriptional activation of p53 responsive genes   (Homo sapiens)


p53-Dependent G1 DNA Damage Response (Homo sapiens)


p53-Dependent G1/S DNA damage checkpoint (Homo sapiens)


Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A (Homo sapiens)


p53-Independent G1/S DNA Damage Checkpoint (Homo sapiens)


G1/S DNA Damage Checkpoints (Homo sapiens)


Mitotic Spindle Checkpoint (Homo sapiens)


Transcriptional  activation of  cell cycle inhibitor p21  (Homo sapiens)


Glycogen breakdown (glycogenolysis) (Homo sapiens)


Metabolism of amino acids and derivatives (Homo sapiens)


Pentose phosphate pathway (Homo sapiens)


Metabolism of carbohydrates and carbohydrate derivatives (Homo sapiens)


Citric acid cycle (TCA cycle) (Homo sapiens)


mRNA Splicing - Major Pathway (Homo sapiens)


mRNA Splicing - Minor Pathway (Homo sapiens)


Processing of Capped Intron-Containing Pre-mRNA (Homo sapiens)


Translation initiation complex formation (Homo sapiens)


Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S (Homo sapiens)


Formation of a pool of free 40S subunits (Homo sapiens)


Formation of the ternary complex, and subsequently, the 43S complex (Homo sapiens)


Ribosomal scanning and start codon recognition (Homo sapiens)


GTP hydrolysis and joining of the 60S ribosomal subunit (Homo sapiens)


Cap-dependent Translation Initiation (Homo sapiens)


Transport of nucleotide sugars (Homo sapiens)


RNA Polymerase I Promoter Opening (Homo sapiens)


RNA Polymerase I Transcription Initiation (Homo sapiens)


RNA Polymerase I Promoter Escape (Homo sapiens)


RNA Polymerase II Promoter Escape (Homo sapiens)


RNA Polymerase II Transcription Pre-Initiation And Promoter Opening (Homo sapiens)


Abasic sugar-phosphate removal via the single-nucleotide replacement pathway (Homo sapiens)


Reversal of alkylation damage by DNA dioxygenases (Homo sapiens)


Gene expression (Transcription) (Homo sapiens)


Insulin receptor signalling cascade (Homo sapiens)


Signaling by Insulin receptor (Homo sapiens)


RNA Polymerase III Abortive And Retractive Initiation (Homo sapiens)


Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex (Homo sapiens)


Processing of Capped Intronless Pre-mRNA (Homo sapiens)


Formation of the Editosome (Homo sapiens)


Activation, myristolyation of BID and translocation to mitochondria (Homo sapiens)


Triglyceride biosynthesis (Homo sapiens)


Dissolution of Fibrin Clot (Homo sapiens)


Platelet Adhesion to exposed collagen (Homo sapiens)


RNA Polymerase II Transcription Initiation (Homo sapiens)


RNA Polymerase II Transcription Elongation (Homo sapiens)


Platelet activation, signaling and aggregation (Homo sapiens)


Response to elevated platelet cytosolic Ca2+ (Homo sapiens)


Platelet Aggregation (Plug Formation) (Homo sapiens)


RNA Polymerase II Transcription Initiation And Promoter Clearance (Homo sapiens)


RNA Polymerase III Transcription Initiation (Homo sapiens)


RNA Polymerase III Transcription Initiation From Type 1 Promoter (Homo sapiens)


RNA Polymerase III Transcription Initiation From Type 2 Promoter (Homo sapiens)


RNA Polymerase III Transcription Initiation From Type 3 Promoter (Homo sapiens)


RNA Pol II CTD phosphorylation and interaction with CE (Homo sapiens)


Utilization of Ketone Bodies (Homo sapiens)


Beta oxidation of myristoyl-CoA to lauroyl-CoA (Homo sapiens)


mitochondrial fatty acid beta-oxidation of saturated fatty acids (Homo sapiens)


mitochondrial fatty acid beta-oxidation of unsaturated fatty acids (Homo sapiens)


Beta oxidation of palmitoyl-CoA to myristoyl-CoA (Homo sapiens)


Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA (Homo sapiens)


Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA (Homo sapiens)


Beta oxidation of octanoyl-CoA to hexanoyl-CoA (Homo sapiens)


Beta oxidation of hexanoyl-CoA to butanoyl-CoA (Homo sapiens)


Beta oxidation of butanoyl-CoA to acetyl-CoA (Homo sapiens)


Processing of Intronless Pre-mRNAs (Homo sapiens)


Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Homo sapiens)


Interferon gamma signaling (Homo sapiens)


Advanced glycosylation endproduct receptor signaling (Homo sapiens)


Interconversion of 2-oxoglutarate and 2-hydroxyglutarate (Homo sapiens)


Gastrin-CREB signalling pathway via PKC and MAPK (Homo sapiens)


ERBB2 Activates PTK6 Signaling (Homo sapiens)


PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Homo sapiens)


Synaptic adhesion-like molecules (Homo sapiens)


Phosphate bond hydrolysis by NTPDase proteins (Homo sapiens)


Butyrophilin (BTN) family interactions (Homo sapiens)


Signaling by FGFR2 IIIa TM (Homo sapiens)


MET activates RAS signaling (Homo sapiens)


MET activates PI3K/AKT signaling (Homo sapiens)


Signaling by FGFR3 fusions in cancer (Homo sapiens)


Interleukin-20 family signaling (Homo sapiens)


Golgi-to-ER retrograde transport (Homo sapiens)


Cargo recognition for clathrin-mediated endocytosis (Homo sapiens)


Clathrin-mediated endocytosis (Homo sapiens)


PTK6 promotes HIF1A stabilization (Homo sapiens)


Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models (Homo sapiens)


Neurodegenerative Diseases (Homo sapiens)


Downregulation of ERBB2 signaling (Homo sapiens)


Reelin signalling pathway (Homo sapiens)


Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Homo sapiens)


E3 ubiquitin ligases ubiquitinate target proteins (Homo sapiens)


Negative regulation of activity of TFAP2 (AP-2) family transcription factors (Homo sapiens)


TFAP2 (AP-2) family regulates transcription of other transcription factors (Homo sapiens)


Activation of the TFAP2 (AP-2) family of transcription factors (Homo sapiens)


TFAP2 (AP-2) family regulates transcription of growth factors and their receptors (Homo sapiens)


TFAP2 (AP-2) family regulates transcription of cell cycle factors (Homo sapiens)


rRNA processing in the mitochondrion (Homo sapiens)


rRNA processing in the nucleus and cytosol (Homo sapiens)


TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation (Homo sapiens)


MET activates PTK2 signaling (Homo sapiens)


InlB-mediated entry of Listeria monocytogenes into host cell (Homo sapiens)


MET interacts with TNS proteins (Homo sapiens)


MET activates RAP1 and RAC1 (Homo sapiens)


MET promotes cell motility (Homo sapiens)


RAB GEFs exchange GTP for GDP on RABs (Homo sapiens)


Listeria monocytogenes entry into host cells (Homo sapiens)


InlA-mediated entry of Listeria monocytogenes into host cells (Homo sapiens)


GABA synthesis, release, reuptake and degradation (Homo sapiens)


Aryl hydrocarbon receptor signalling (Homo sapiens)


Collagen chain trimerization (Homo sapiens)


Calnexin/calreticulin cycle (Homo sapiens)


Interferon alpha/beta signaling (Homo sapiens)


Interleukin receptor SHC signaling (Homo sapiens)


Regulation of signaling by CBL (Homo sapiens)


TRAF3-dependent IRF activation pathway (Homo sapiens)


Nonsense-Mediated Decay (NMD) (Homo sapiens)


TRAF6 mediated IRF7 activation (Homo sapiens)


TRAF6 mediated NF-kB activation (Homo sapiens)


NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 (Homo sapiens)


Ion transport by P-type ATPases (Homo sapiens)


Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) (Homo sapiens)


IKK complex recruitment mediated by RIP1 (Homo sapiens)


IRAK2 mediated activation of TAK1 complex (Homo sapiens)


TRIF (TICAM1)-mediated TLR4 signaling  (Homo sapiens)


TRAF6-mediated induction of TAK1 complex within TLR4 complex (Homo sapiens)


Molybdenum cofactor biosynthesis (Homo sapiens)


Transport to the Golgi and subsequent modification (Homo sapiens)


TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling (Homo sapiens)


TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Homo sapiens)


IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Homo sapiens)


MyD88 dependent cascade initiated on endosome (Homo sapiens)


IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Homo sapiens)


N-glycan antennae elongation in the medial/trans-Golgi (Homo sapiens)


N-Glycan antennae elongation (Homo sapiens)


Reactions specific to the complex N-glycan synthesis pathway (Homo sapiens)


Retinoid metabolism and transport (Homo sapiens)


MyD88 cascade initiated on plasma membrane (Homo sapiens)


Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Homo sapiens)


Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Homo sapiens)


Termination of O-glycan biosynthesis (Homo sapiens)


GABA B receptor activation (Homo sapiens)


Growth hormone receptor signaling (Homo sapiens)


Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Homo sapiens)


Factors involved in megakaryocyte development and platelet production (Homo sapiens)


Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Homo sapiens)


Signaling by the B Cell Receptor (BCR) (Homo sapiens)


Activation of GABAB receptors (Homo sapiens)


Inhibition  of voltage gated Ca2+ channels via Gbeta/gamma subunits (Homo sapiens)


Extravasation of Diagnostic and Therapeutic Materials


Hyperglycemic Hyperosmolar Nonketotic Coma


Precursor B-Cell Lymphoblastic Leukemia-Lymphoma


Congenital, Hereditary, and Neonatal Diseases and Abnormalities


Congenital abnormality of respiratory system


Pathological Conditions, Signs and Symptoms


Tachycardia, Atrioventricular Nodal Reentry


insecticidal crystal protein, Bacillus Thuringiensis


pituitary adenylate cyclase activating polypeptide


Amb a I protein, Ambrosia artemisiifolia


testosterone-3-carboxymethyloxime-bovine serum albumin conjugate


tissue plasminogen activator-(staphylococcal A, B fragment) dimer


vasopressin, 1-(1-mercaptocyclohexaneacetic acid)-2-(O- methyl-L-tyrosine)-8-L-arginine-


atrial natriuretic factor (4-23)NH2, de-Gln(18)-de-Ser(19)-de-Gly(20,22)-de-Leu(21)-


alpha helical corticotropin-releasing hormone


Dermatophagoides pteronyssinus antigen p 1


Glial Cell Line-Derived Neurotrophic Factor


vasopressin, beta mercapto(beta,beta)-cyclopentamethylenepropionic acid(1)-Phe(2)-Ile(4)-Arg(8)-Ala(9)-


thrombin receptor-activating peptide SFLLRNPNDKY


Schizophrenia Spectrum and Other Psychotic Disorders


Dermatophagoides pteronyssinus antigen p 2


interleukin 6-interleukin 6 receptor fusion protein, recombinant


phenylalanyl corticotropin-releasing factor (12-41)


Central Nervous System Fungal Infections


Lead Poisoning, Nervous System, Childhood


Alcohol-Induced Disorders, Nervous System


Central Nervous System Bacterial Infections


anticoagulation factor II, Agkistrodon acutus


bovine serum albumin-corticosterone conjugate


myelin oligodendrocyte glycoprotein (35-55)


beta-adrenergic receptor kinase inhibitory peptide


Intercellular Signaling Peptides and Proteins


benzyloxycarbonyltyrosyl-valyl-alanyl-aspartic acid fluoromethyl ketone


TMVA protein, Trimeresurus mucrosquamatus


benzyloxycarbonyl-alanyl-glutamyl-valyl-aspartic acid fluoromethyl ketone


rhodocytin protein, Calloselasma rhodostoma


stejnulxin protein, Trimeresurus stejnegeri


myristoylated autocamtide-2-related inhibitory peptide


substance P (6-11), Tyr(6)-D-Phe(7)-D-His(9)-


Interleukin 1 Receptor Antagonist Protein


(O,O-diisopropyl phosphoryl-L-tryptophan)(2)-L-lysine methyl ester


MUSCULAR DYSTROPHY, LIMB-GIRDLE, TYPE 1C


Hypocalcemia, Autosomal Dominant, with Bartter Syndrome


Metaphyseal Dysplasia with Maxillary Hypoplasia and Brachydactyly


Myasthenic Syndrome, Congenital, with Facial Dysmorphism, associated with Acetylcholine Receptor Deficiency


Myasthenic Syndrome, Congenital, Fast-Channel


Invasive Pneumococcal Disease, Recurrent Isolated, 2


SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE 5


DYSKERATOSIS CONGENITA, AUTOSOMAL DOMINANT


ICHTHYOSIFORM ERYTHRODERMA, CONGENITAL, NONBULLOUS, 1


Cerebellar Ataxia, Deafness, and Narcolepsy


Transient Myeloproliferative Disorder of Down Syndrome


Leukemia, Megakaryoblastic, of Down Syndrome


Dehydrated Hereditary Stomatocytosis, Pseudohyperkalemia, and Perinatal Edema


Renal Tubular Acidosis, Distal, With Hemolytic Anemia


Lys49-phospholipase A2, Bothrops lternatus


Kidney disorder involving deposition of calcium and oxalate or phosphate in the renal tubules


Idiopathic intracranial hypertension with papilledema


Hypopituitarism and septooptic 'dysplasia'


Lynch syndrome I (site-specific colonic cancer)


Deafness, autosomal dominant nonsyndromic sensorineural 17


Clear-cell metastatic renal cell carcinoma


Speech disturbance - use of faulty phrasing and unrelated words


Congenital Bone Marrow Failure Syndromes


stromatoxin protein, Stromatopelma calceata


malondialdehyde-low density lipoprotein, human


Lactic Acidosis, Congenital Infantile, Due To Lad Deficiency


Autoimmune polyendocrinopathy syndrome, type 1


Glutathione Peroxidase Deficiency, Hemolytic Anemia possibly due to


Bleeding Disorder due to Defective Thromboxane A2 Receptor


Thrombophilia, Hereditary, Due To Protein S Deficiency, Autosomal Recessive


Thrombophilia, Hereditary, Due To Protein S Deficiency, Autosomal Dominant


Dyskeratosis Congenita, Autosomal Recessive


Adrenal Insufficiency, Congenital, With 46,Xy Sex Reversal


Microcephaly with Chorioretinopathy, Autosomal Recessive


Palmoplantar Hyperkeratosis with Squamous Cell Carcinoma of Skin and Sex Reversal


Epileptic encephalopathy, Lennox-Gastaut type


Avoidant Restrictive Food Intake Disorder


Metabolic Side Effects of Drugs and Substances


Neutrophil Chemotactic Response, Abnormal


Chronic Kidney Diseases of Uncertain Etiology


Traumatic intraparenchymal cerebral hemorrhage


2,6-dimethyl-4-(2'-nitrosophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester


acetylenedicarboxylic acid dimethyl ester


caffeine, sodium benzoate drug combination


diethylene glycol dimethacrylate polymer