endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)


biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)


nervous system process involved in regulation of systemic arterial blood pressure


acute inflammatory response to antigenic stimulus


positive regulation of inflammatory response to antigenic stimulus


positive regulation of acute inflammatory response to antigenic stimulus


regulation of vascular associated smooth muscle contraction


positive regulation of blood pressure by epinephrine-norepinephrine


mitochondrial electron transport, NADH to ubiquinone


C21-steroid hormone biosynthetic process


porphyrin-containing compound metabolic process


cellular response to nitrogen starvation


biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

adenylate cyclase-activating G protein-coupled receptor signaling pathway


phospholipase C-activating G protein-coupled receptor signaling pathway


tyrosine phosphorylation of STAT protein


regulation of smoothened signaling pathway


vascular associated smooth muscle contraction


spinal cord motor neuron differentiation


forebrain radial glial cell differentiation


intracellular monoatomic anion homeostasis


negative regulation of nucleotide biosynthetic process


negative regulation of B cell proliferation


post-embryonic camera-type eye development


negative regulation of nervous system process


positive regulation of interleukin-5 production


negative regulation of DNA-templated transcription, elongation


negative regulation of viral transcription


negative regulation of activin receptor signaling pathway


positive regulation of protein sumoylation


regulation of transcription elongation by RNA polymerase II


negative regulation of dephosphorylation


regulation of peroxisome proliferator activated receptor signaling pathway


positive regulation of peroxisome proliferator activated receptor signaling pathway


negative regulation of multicellular organism growth


positive regulation of embryonic development


regulation of fibroblast growth factor receptor signaling pathway


negative regulation of T cell proliferation


inner ear auditory receptor cell differentiation


positive regulation of tyrosine phosphorylation of STAT protein


thiamine-containing compound metabolic process


positive regulation of macrophage activation


positive regulation of vascular permeability


negative regulation of fat cell differentiation


negative regulation of endothelial cell differentiation


positive regulation of fibroblast growth factor receptor signaling pathway


short-chain fatty acid metabolic process


negative regulation of alpha-beta T cell proliferation


cell morphogenesis involved in neuron differentiation


calcium ion-regulated exocytosis of neurotransmitter


chondroitin sulfate proteoglycan metabolic process


regulation of lipoprotein metabolic process


negative regulation of membrane protein ectodomain proteolysis


negative regulation of small GTPase mediated signal transduction


negative regulation of lymphocyte activation


regulation of response to type II interferon


type II interferon-mediated signaling pathway


epithelial tube branching involved in lung morphogenesis


positive regulation of epithelial cell proliferation involved in lung morphogenesis


regulation of vitamin D biosynthetic process


regulation of morphogenesis of a branching structure


regulation of branching involved in salivary gland morphogenesis


smoothened signaling pathway involved in dorsal/ventral neural tube patterning


cardiac vascular smooth muscle cell differentiation


regulation of dendritic spine development


negative regulation of dendritic spine development


regulation of branching involved in lung morphogenesis


leukocyte adhesion to vascular endothelial cell


negative regulation of neuron projection regeneration


negative regulation of leukocyte proliferation


regulation of phospholipid biosynthetic process


positive regulation of granulocyte chemotaxis


establishment of epithelial cell polarity


maintenance of postsynaptic specialization structure


neurotransmitter receptor localization to postsynaptic specialization membrane


positive regulation of secondary metabolite biosynthetic process


positive regulation of trophoblast cell migration


regulation of endothelial tube morphogenesis


regulation of superoxide dismutase activity


positive regulation of cell cycle G2/M phase transition


negative regulation of leukocyte cell-cell adhesion


regulation of TRAIL-activated apoptotic signaling pathway


negative regulation of bicellular tight junction assembly


positive regulation of microglial cell activation


midbrain dopaminergic neuron differentiation


positive regulation of protein localization to membrane


regulation of postsynaptic density organization


positive regulation of non-canonical Wnt signaling pathway


regulation of branching morphogenesis of a nerve


positive regulation of hepatocyte proliferation


regulation of ovarian follicle development


leukocyte adhesion to arterial endothelial cell


negative regulation of ATP biosynthetic process


negative regulation of nodal signaling pathway


negative regulation of phosphatase activity


negative regulation of receptor signaling pathway via JAK-STAT


negative regulation of ribosome biogenesis


negative regulation of vascular wound healing


positive regulation of amyloid precursor protein biosynthetic process


pyrimidine deoxyribonucleoside metabolic process


regulation of leukocyte adhesion to arterial endothelial cell


Arp2/3 protein complex

biolink:CellularComponent biolink:AnatomicalEntity biolink:PhysicalEssence biolink:OrganismalEntity biolink:SubjectOfInvestigation biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent


NMDA selective glutamate receptor complex


biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent


ATP-dependent DNA/DNA annealing activity


azole transmembrane transporter activity


calmodulin-dependent protein phosphatase activity


histone H3K14 deacetylase activity, hydrolytic mechanism


L-ornithine transmembrane transporter activity


ligand-gated monoatomic cation channel activity


ligand-gated monoatomic ion channel activity


long-chain fatty acid-CoA ligase activity


lysophosphatidic acid phosphatase activity


NAD-dependent protein lysine deacetylase activity


oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor


phosphatidylinositol monophosphate phosphatase activity


phosphatidylinositol phosphate 4-phosphatase activity


RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding


sialic acid transmembrane transporter activity


transferase activity, transferring nitrogenous groups


ubiquitin-like ligase-substrate adaptor activity


very long-chain fatty acid-CoA ligase activity


Glycosaminoglycan-protein linkage region biosynthesis (Homo sapiens)


ciliary basal body-plasma membrane docking


Chondroitin sulfate/dermatan sulfate metabolism (Homo sapiens)


Class A/1 (Rhodopsin-like receptors) (Homo sapiens)


Constitutive Signaling by AKT1 E17K in Cancer (Homo sapiens)


Defective EXT2 causes exostoses 2 (Homo sapiens)


Estrogen-stimulated signaling through PRKCZ (Homo sapiens)


Factors involved in megakaryocyte development and platelet production (Homo sapiens)


G alpha (12/13) signalling events (Homo sapiens)


Gastrin-CREB signalling pathway via PKC and MAPK (Homo sapiens)


Heparan sulfate/heparin (HS-GAG) metabolism (Homo sapiens)


heparan sulfate proteoglycan catabolic process


Interleukin-20 family signaling (Homo sapiens)


LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production (Homo sapiens)


Maturation of nucleoprotein (Homo sapiens)


Maturation of spike protein (Homo sapiens)


Mitochondrial iron-sulfur cluster biogenesis (Homo sapiens)


NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis (Homo sapiens)


NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake  (Homo sapiens)


NRAGE signals death through JNK (Homo sapiens)


Organic anion transporters (Homo sapiens)


Peroxisomal lipid metabolism (Homo sapiens)


PI5P Regulates TP53 Acetylation (Homo sapiens)


regulation of type II interferon-mediated signaling pathway


regulation of pyruvate decarboxylation to acetyl-CoA


Signaling by FGFR3 fusions in cancer (Homo sapiens)


Signaling by FLT3 ITD and TKD mutants (Homo sapiens)


Signaling by Retinoic Acid (Homo sapiens)


The canonical retinoid cycle in rods (twilight vision) (Homo sapiens)


Translation of Structural Proteins (Homo sapiens)


Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Homo sapiens)


Transport of vitamins, nucleosides, and related molecules (Homo sapiens)


G protein-coupled receptor internalization


positive regulation of receptor internalization


wound healing involved in inflammatory response


complement receptor mediated signaling pathway


antigen processing and presentation via MHC class Ib


positive regulation of natural killer cell mediated immunity


pyrimidine nucleoside monophosphate biosynthetic process


deoxyribonucleoside monophosphate biosynthetic process


pyrimidine deoxyribonucleotide biosynthetic process


isopentenyl diphosphate biosynthetic process


positive regulation of lamellipodium assembly


negative regulation of macrophage derived foam cell differentiation


negative regulation of cell morphogenesis


regulation of triglyceride biosynthetic process


negative regulation of transcription by RNA polymerase I


forebrain ventricular zone progenitor cell division


negative regulation of actin filament polymerization


regulation of vascular endothelial growth factor receptor signaling pathway


negative regulation of vascular endothelial growth factor receptor signaling pathway


positive regulation of vascular endothelial growth factor receptor signaling pathway


regulation of cell projection organization


nuclear receptor-mediated corticosteroid signaling pathway


peripheral nervous system myelin maintenance


positive regulation of phospholipase A2 activity


positive regulation of myeloid cell apoptotic process


regulation of intracellular steroid hormone receptor signaling pathway


regulation of cell-cell adhesion mediated by integrin


nucleobase-containing small molecule catabolic process


meiotic DNA double-strand break formation


regulation of respiratory gaseous exchange


double-strand break repair via synthesis-dependent strand annealing


positive regulation of cholesterol biosynthetic process


regulation of protein export from nucleus


positive regulation of protein export from nucleus


antigen processing and presentation of lipid antigen via MHC class Ib


3'-phosphoadenosine 5'-phosphosulfate biosynthetic process


regulation of neurotrophin TRK receptor signaling pathway


negative regulation of transmission of nerve impulse


nucleobase-containing small molecule metabolic process


chorionic trophoblast cell differentiation


intestinal epithelial structure maintenance


positive regulation of cartilage development


protein modification by small protein removal


establishment of protein localization to chromatin


cellular response to epinephrine stimulus


negative regulation of kidney development


negative regulation of cellular response to growth factor stimulus


positive regulation of intracellular protein transport


positive regulation of animal organ morphogenesis


positive regulation of G1/S transition of mitotic cell cycle


glucosamine-containing compound metabolic process


carbohydrate derivative biosynthetic process


positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway


negative regulation of cellular response to vascular endothelial growth factor stimulus


positive regulation of lamellipodium organization


negative regulation of response to endoplasmic reticulum stress


regulation of membrane repolarization during cardiac muscle cell action potential


negative regulation of guanyl-nucleotide exchange factor activity


positive regulation of fibroblast apoptotic process


negative regulation of synaptic vesicle exocytosis


regulation of nuclear receptor-mediated glucocorticoid signaling pathway


regulation of clathrin-dependent endocytosis


regulation of motor neuron apoptotic process


negative regulation of cytoplasmic translation


myotube differentiation involved in skeletal muscle regeneration


positive regulation of natural killer cell mediated cytotoxicity


pyridine-containing compound catabolic process


pyrimidine deoxyribonucleoside monophosphate metabolic process


pyrimidine nucleoside monophosphate metabolic process


regulation of mitochondrial mRNA stability


asymmetric, glutamatergic, excitatory synapse


presynaptic active zone cytoplasmic component


trans-Golgi network transport vesicle membrane


tricarboxylic acid cycle heteromeric enzyme complex


choline transmembrane transporter activity


histone H3K4me/H3K4me2/H3K4me3 demethylase activity


hydrolase activity, hydrolyzing N-glycosyl compounds


ligase activity, forming carbon-carbon bonds


all-trans-retinol dehydrogenase (NADP+) activity


oxalate transmembrane transporter activity


oxidoreductase activity, acting on the aldehyde or oxo group of donors


oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor


oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor


oxidoreductase activity, acting on the CH-NH group of donors


oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor


protein kinase A catalytic subunit binding


protein kinase A regulatory subunit binding


protein transmembrane transporter activity


pyruvate transmembrane transporter activity


mRNA regulatory element binding translation repressor activity


Binding of TCF/LEF:CTNNB1 to target gene promoters (Homo sapiens)


dolichol-linked oligosaccharide biosynthetic process


Cooperation of Prefoldin and TriC/CCT  in actin and tubulin folding (Homo sapiens)


Defects in biotin (Btn) metabolism (Homo sapiens)


Initiation of Nuclear Envelope (NE) Reformation (Homo sapiens)


Interferon gamma signaling (Homo sapiens)


IRE1alpha activates chaperones (Homo sapiens)


MET activates RAP1 and RAC1 (Homo sapiens)


mRNA Splicing - Minor Pathway (Homo sapiens)


Multifunctional anion exchangers (Homo sapiens)


RUNX3 Regulates Immune Response and Cell Migration (Homo sapiens)


Sema4D mediated inhibition of cell attachment and migration (Homo sapiens)


Synthesis of PIPs at the early endosome membrane (Homo sapiens)


Synthesis of PIPs at the ER membrane (Homo sapiens)


Trafficking of GluR2-containing AMPA receptors (Homo sapiens)


Transcriptional activation of mitochondrial biogenesis (Homo sapiens)


Transport and metabolism of PAPS (Homo sapiens)


alternative mRNA splicing, via spliceosome


renal system process involved in regulation of blood volume


regulation of angiotensin levels in blood


cytokine production involved in immune response


leukocyte migration involved in inflammatory response


negative regulation of cellular extravasation


negative regulation of cytokine production involved in immune response


negative regulation of T cell cytokine production


negative regulation of peptide secretion


negative regulation of T-helper 1 type immune response


negative regulation of response to biotic stimulus


developmental process involved in reproduction


regulation of systemic arterial blood pressure


negative regulation of systemic arterial blood pressure


fructose 2,6-bisphosphate metabolic process


generation of precursor metabolites and energy


transcription initiation at RNA polymerase III promoter


glutamine family amino acid biosynthetic process


negative regulation of striated muscle cell apoptotic process


regulation of gamma-aminobutyric acid secretion


long-chain fatty acid import across plasma membrane


forebrain dorsal/ventral pattern formation


tangential migration from the subventricular zone to the olfactory bulb


maintenance of gastrointestinal epithelium


regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity


positive regulation of lipopolysaccharide-mediated signaling pathway


negative regulation of response to external stimulus


negative regulation of chemokine production


negative regulation of type II interferon production


negative regulation of interleukin-1 beta production


negative regulation of interleukin-1 production


negative regulation of interleukin-10 production


positive regulation of interleukin-1 production


regulation of natural killer cell differentiation


negative regulation of homotypic cell-cell adhesion


regulation of heterotypic cell-cell adhesion


positive regulation of heterotypic cell-cell adhesion


low-density lipoprotein particle remodeling


non-canonical NF-kappaB signal transduction


snRNA transcription by RNA polymerase III


biological process involved in interspecies interaction between organisms


positive regulation by host of viral process


negative regulation of meiotic nuclear division


regulation of photoreceptor cell differentiation


regulation of short-term neuronal synaptic plasticity


positive regulation of oligodendrocyte differentiation


defense response to Gram-positive bacterium


regulation of ubiquitin-protein transferase activity


negative regulation of ubiquitin-protein transferase activity


negative regulation of meiotic cell cycle


regulation of killing of cells of another organism


positive regulation of mitochondrial depolarization


cell differentiation involved in embryonic placenta development


labyrinthine layer blood vessel development


epithelial cell differentiation involved in prostate gland development


arterial endothelial cell differentiation


negative regulation of insulin secretion involved in cellular response to glucose stimulus


Notch signaling involved in heart development


glycolytic process through fructose-6-phosphate


negative regulation of chemokine-mediated signaling pathway


neurotransmitter-gated ion channel clustering


positive regulation of sphingolipid biosynthetic process


regulation of locomotion involved in locomotory behavior


receptor localization to non-motile cilium


regulation of neurotransmitter receptor localization to postsynaptic specialization membrane


excitatory chemical synaptic transmission


postsynaptic modulation of chemical synaptic transmission


regulation of non-canonical NF-kappaB signal transduction


nucleoside phosphate biosynthetic process


negative regulation of proteasomal protein catabolic process


positive regulation of non-motile cilium assembly


negative regulation of protein targeting to mitochondrion


positive regulation of metalloendopeptidase activity


regulation of excitatory synapse assembly


regulation of vascular associated smooth muscle cell dedifferentiation


negative regulation of reproductive process


positive regulation of T-helper 2 cell cytokine production


regulation of thyroid hormone generation


regulation of transcription regulatory region DNA binding


positive regulation of transcription regulatory region DNA binding


cellular response to molecule of bacterial origin


L-arginine import across plasma membrane


leukocyte chemotaxis involved in inflammatory response


negative regulation of cholesterol metabolic process


negative regulation of dopamine secretion


negative regulation of neutrophil migration


positive regulation of interleukin-1 beta production


protein localization to cell-cell junction


regulation of mitochondrial DNA replication


regulation of Rab protein signal transduction


ribonucleoside diphosphate metabolic process


sRNA-mediated post-transcriptional gene silencing


mitochondrial permeability transition pore complex


RNA polymerase III transcription regulator complex


ABC-type glutathione S-conjugate transporter activity


ABC-type xenobiotic transporter activity


modified amino acid transmembrane transporter activity


monocarboxylic acid transmembrane transporter activity


organic acid transmembrane transporter activity


organic anion transmembrane transporter activity


oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen


RNA polymerase II C-terminal domain binding


sulfur compound transmembrane transporter activity


transferase activity, transferring phosphorus-containing groups


xenobiotic transmembrane transporter activity


Activated NTRK2 signals through FRS2 and FRS3 (Homo sapiens)


Amino acids regulate mTORC1 (Homo sapiens)


Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Homo sapiens)


Beta-oxidation of pristanoyl-CoA (Homo sapiens)


DNA replication initiation (Homo sapiens)


Glutathione synthesis and recycling (Homo sapiens)


GRB2:SOS provides linkage to MAPK signaling for Integrins  (Homo sapiens)


Interleukin-35 Signalling (Homo sapiens)


Metabolism of vitamins and cofactors (Homo sapiens)


positive regulation of transcription of Notch receptor target


p130Cas linkage to MAPK signaling for integrins (Homo sapiens)


RAB GEFs exchange GTP for GDP on RABs (Homo sapiens)


Regulation of gene expression by Hypoxia-inducible Factor (Homo sapiens)


Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells (Homo sapiens)


RHO GTPases Activate ROCKs (Homo sapiens)


RUNX3 regulates NOTCH signaling (Homo sapiens)


Signaling by cytosolic FGFR1 fusion mutants (Homo sapiens)


STAT3 nuclear events downstream of ALK signaling (Homo sapiens)


Synthesis, secretion, and deacylation of Ghrelin (Homo sapiens)


positive regulation of receptor recycling


negative regulation of receptor internalization


hematopoietic progenitor cell differentiation


antigen processing and presentation of peptide antigen via MHC class I


antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway


negative regulation of acute inflammatory response


negative regulation of immune system process


negative regulation of natural killer cell mediated immunity


negative regulation of myeloid leukocyte mediated immunity


regulation of systemic arterial blood pressure by endothelin


regulation of nucleotide metabolic process


transcription initiation at RNA polymerase II promoter


regulation of endothelial cell migration


negative regulation of epithelial cell migration


negative regulation of platelet-derived growth factor receptor signaling pathway


negative regulation of muscle cell apoptotic process


negative regulation of plasminogen activation


positive regulation of fibroblast migration


positive regulation of glucose metabolic process


negative regulation of macrophage cytokine production


negative regulation of muscle adaptation


regulation of anatomical structure morphogenesis


positive regulation of protein modification process


positive regulation of mRNA 3'-end processing


negative regulation of NF-kappaB transcription factor activity


regulation of response to external stimulus


positive regulation of hormone metabolic process


negative regulation of interleukin-8 production


positive regulation of interleukin-4 production


negative regulation of cell adhesion mediated by integrin


negative regulation of toll-like receptor signaling pathway


positive regulation of smooth muscle cell apoptotic process


negative regulation of mitochondrial membrane permeability


TRAIL-activated apoptotic signaling pathway


positive regulation of multicellular organism growth


positive regulation of catalytic activity


positive regulation of MAP kinase activity


regulation of carbohydrate catabolic process


phosphatidylinositol 3-kinase/protein kinase B signal transduction


positive regulation of JUN kinase activity


negative regulation of DNA damage response, signal transduction by p53 class mediator


negative regulation of blood vessel endothelial cell migration


mitochondrial fragmentation involved in apoptotic process


development of secondary sexual characteristics


negative regulation of MHC class II biosynthetic process


regulation of gamma-delta T cell differentiation


negative regulation of regulatory T cell differentiation


regulation of T-helper 2 cell differentiation


positive regulation of T-helper 2 cell differentiation


regulation of macrophage differentiation


negative regulation of macrophage differentiation


positive regulation of glycolytic process


positive regulation of carbohydrate metabolic process


development of secondary female sexual characteristics


response to arsenic-containing substance


retinoic acid receptor signaling pathway


positive regulation of skeletal muscle tissue development


branching morphogenesis of an epithelial tube


homeostasis of number of cells within a tissue


negative regulation of inflammatory response


detection of mechanical stimulus involved in sensory perception of sound


negative regulation of nitric-oxide synthase activity


regulation of membrane protein ectodomain proteolysis


negative regulation of cytosolic calcium ion concentration


establishment of centrosome localization


biological process involved in interaction with symbiont


negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction


negative regulation of cardiac muscle cell proliferation


negative regulation of post-transcriptional gene silencing


negative regulation of response to type II interferon


regulation of type I interferon-mediated signaling pathway


negative regulation of type I interferon-mediated signaling pathway


regulation of Fc receptor mediated stimulatory signaling pathway


regulation of response to cytokine stimulus


negative regulation of response to cytokine stimulus


cell fate commitment involved in formation of primary germ layer


positive regulation of dendritic spine development


regulation of proteasomal protein catabolic process


cell adhesion involved in heart morphogenesis


regulation of stress-activated protein kinase signaling cascade


positive regulation of stress-activated protein kinase signaling cascade


neutrophil-mediated killing of symbiont cell


regulation of neutrophil mediated cytotoxicity


positive regulation of transforming growth factor beta production


regulation of protein serine/threonine kinase activity


positive regulation of protein serine/threonine kinase activity


mesenchymal stem cell maintenance involved in nephron morphogenesis


microtubule anchoring at microtubule organizing center


positive regulation of kidney development


negative regulation of oxidative phosphorylation


positive regulation of inhibitory postsynaptic potential


modulation of excitatory postsynaptic potential


regulation of neuron projection arborization


positive regulation of cellular response to insulin stimulus


positive regulation of endoplasmic reticulum unfolded protein response


regulation of hyaluronan biosynthetic process


negative regulation of amyloid-beta clearance


negative regulation of relaxation of muscle


negative regulation of non-canonical NF-kappaB signal transduction


negative regulation of protein acetylation


semaphorin-plexin signaling pathway involved in neuron projection guidance


negative regulation of stem cell population maintenance


negative regulation of intracellular signal transduction


regulation of cell cycle G1/S phase transition


negative regulation of miRNA transcription


positive regulation of miRNA transcription


negative regulation of alcohol biosynthetic process


negative regulation of response to wounding


negative regulation of protein maturation


positive regulation of protein maturation


regulation of endoplasmic reticulum tubular network organization


negative regulation of sprouting angiogenesis


positive regulation of glial cell migration


regulation of somatic stem cell population maintenance


negative regulation of somatic stem cell population maintenance


negative regulation of apoptotic process involved in development


regulation of epithelial to mesenchymal transition involved in endocardial cushion formation


vascular associated smooth muscle cell apoptotic process


positive regulation of macrophage migration


negative regulation of vascular endothelial cell proliferation


positive regulation of response to endoplasmic reticulum stress


negative regulation of lipid localization


regulation of cell-cell adhesion mediated by cadherin


positive regulation of cell-cell adhesion mediated by cadherin


regulation of macrophage apoptotic process


negative regulation of macrophage apoptotic process


positive regulation of fatty acid transport


positive regulation of excitatory postsynaptic potential


positive regulation of blood vessel remodeling


regulation of peptidyl-lysine acetylation


negative regulation of peptidyl-lysine acetylation


negative regulation of mesenchymal cell apoptotic process


regulation of dendritic cell differentiation


negative regulation of dendritic cell differentiation


positive regulation of apoptotic signaling pathway


regulation of intrinsic apoptotic signaling pathway


angiogenesis involved in coronary vascular morphogenesis


apoptotic process involved in blood vessel morphogenesis


biological process involved in symbiotic interaction


connective tissue replacement involved in inflammatory response wound healing


mature conventional dendritic cell differentiation


negative regulation of ATP metabolic process


negative regulation of cellular respiration


positive regulation of ATP metabolic process


positive regulation of endothelial cell-matrix adhesion via fibronectin


positive regulation of gamma-delta T cell differentiation


positive regulation of nucleotide metabolic process


positive regulation of skeletal muscle tissue growth


regulation of leukocyte mediated cytotoxicity


regulation of vesicle transport along microtubule


signaling receptor ligand precursor processing


cytoplasmic side of endoplasmic reticulum membrane


endoplasmic reticulum-Golgi intermediate compartment


endoplasmic reticulum-plasma membrane contact site


eukaryotic translation initiation factor 2B complex


RNA polymerase II transcription regulator complex


cytosolic translation preinitiation complex


aspartic endopeptidase activity, intramembrane cleaving


basic amino acid transmembrane transporter activity


DNA-binding transcription repressor activity


G protein-coupled chemoattractant receptor activity


guanyl-nucleotide exchange factor activity


L-leucine transmembrane transporter activity


mitogen-activated protein kinase kinase kinase binding


mitogen-activated protein kinase p38 binding


monoamine transmembrane transporter activity


natural killer cell lectin-like receptor binding


non-membrane spanning protein tyrosine phosphatase activity


phosphatidylinositol bisphosphate phosphatase activity


phosphotransferase activity, phosphate group as acceptor


protein serine/threonine kinase inhibitor activity


sequence-specific single stranded DNA binding


translation factor activity, RNA binding


Activation of kainate receptors upon glutamate binding (Homo sapiens)


Activation of RAS in B cells (Homo sapiens)


Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S (Homo sapiens)


BMAL1:CLOCK,NPAS2 activates circadian expression (Homo sapiens)


CDC6 association with the ORC:origin complex (Homo sapiens)


Cytokine Signaling in Immune system (Homo sapiens)


Defective CSF2RB causes SMDP5 (Homo sapiens)


Diseases associated with O-glycosylation of proteins (Homo sapiens)


Dissolution of Fibrin Clot (Homo sapiens)


DNA Replication Pre-Initiation (Homo sapiens)


Energy dependent regulation of mTOR by LKB1-AMPK (Homo sapiens)


FLT3 signaling in disease (Homo sapiens)


Formation of Senescence-Associated Heterochromatin Foci (SAHF) (Homo sapiens)


FOXO-mediated transcription (Homo sapiens)


FOXO-mediated transcription of cell death genes (Homo sapiens)


Glycogen storage diseases (Homo sapiens)


Interferon alpha/beta signaling (Homo sapiens)


mTORC1-mediated signalling (Homo sapiens)


Myoclonic epilepsy of Lafora (Homo sapiens)


Negative regulation of MAPK pathway (Homo sapiens)


Non-integrin membrane-ECM interactions (Homo sapiens)


Orc1 removal from chromatin (Homo sapiens)


Pentose phosphate pathway (Homo sapiens)


Platelet Aggregation (Plug Formation) (Homo sapiens)


Protein-protein interactions at synapses (Homo sapiens)


Regulation of lipid metabolism by PPARalpha (Homo sapiens)


Response of EIF2AK4 (GCN2) to amino acid deficiency (Homo sapiens)


Response to elevated platelet cytosolic Ca2+ (Homo sapiens)


Retinoid cycle disease events (Homo sapiens)


RNA Polymerase III Transcription Initiation From Type 1 Promoter (Homo sapiens)


SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion (Homo sapiens)


Signaling by NTRK3 (TRKC) (Homo sapiens)


SRP-dependent cotranslational protein targeting to membrane


SUMOylation of intracellular receptors (Homo sapiens)


Switching of origins to a post-replicative state (Homo sapiens)


Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Homo sapiens)


TFAP2 (AP-2) family regulates transcription of cell cycle factors (Homo sapiens)


ribosomal large subunit export from nucleus


small nucleolar ribonucleoprotein complex assembly


resolution of meiotic recombination intermediates


regulation of respiratory gaseous exchange by nervous system process


somatic diversification of immune receptors via somatic mutation


positive regulation of T cell mediated immunity


positive regulation of T cell cytokine production


positive regulation of adaptive immune response


positive regulation of type 2 immune response


epithelial to mesenchymal transition involved in endocardial cushion formation


regulation of transcription by RNA polymerase I


protein processing involved in protein targeting to mitochondrion


heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules


glutamine family amino acid metabolic process


positive regulation of platelet activation


negative regulation of epithelial to mesenchymal transition


positive regulation of plasminogen activation


positive regulation of mitochondrial membrane potential


regulation of neuron projection development


regulation of lipoprotein particle clearance


negative regulation of lipoprotein particle clearance


regulation of low-density lipoprotein particle clearance


negative regulation of low-density lipoprotein particle clearance


negative regulation of glutamate secretion


phenol-containing compound catabolic process


positive regulation of epithelial cell differentiation


positive regulation of cell projection organization


brain-derived neurotrophic factor receptor signaling pathway


protection from non-homologous end joining at telomere


negative regulation of nuclease activity


endosome to lysosome transport via multivesicular body sorting pathway


positive regulation of interferon-beta production


low-density lipoprotein receptor particle metabolic process


negative regulation of organic acid transport


establishment of sister chromatid cohesion


low-density lipoprotein particle clearance


maintenance of apical/basal cell polarity


regulation of Golgi to plasma membrane protein transport


telomere maintenance in response to DNA damage


regulation of respiratory system process


negative regulation by host of viral genome replication


DNA-templated DNA replication maintenance of fidelity


protein insertion into mitochondrial inner membrane


positive regulation of neuron differentiation


positive regulation of osteoclast differentiation


positive regulation of meiotic nuclear division


positive regulation of membrane potential


positive regulation of RNA polymerase II transcription preinitiation complex assembly


negative regulation of DNA recombination


positive regulation of DNA recombination


positive regulation of transcription by RNA polymerase I


regulation of response to osmotic stress


positive regulation of astrocyte differentiation


detection of stimulus involved in sensory perception


detection of mechanical stimulus involved in sensory perception


positive regulation of meiotic cell cycle


negative regulation of amino acid transport


ventricular cardiac muscle cell development


positive regulation of sarcomere organization


branch elongation involved in ureteric bud branching


mammary gland branching involved in pregnancy


lymphatic endothelial cell differentiation


protein localization to chromosome, telomeric region


establishment of protein localization to chromosome


positive regulation of glycogen metabolic process


cellular response to parathyroid hormone stimulus


positive regulation of mononuclear cell migration


positive regulation of synapse maturation


regulation of retinal ganglion cell axon guidance


hypoxia-inducible factor-1alpha signaling pathway


regulation of membrane depolarization during action potential


negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway


negative regulation of high voltage-gated calcium channel activity


positive regulation of cell cycle checkpoint


regulation of apoptotic DNA fragmentation


regulation of organelle transport along microtubule


regulation of synaptic vesicle transport


positive regulation of protein deubiquitination


negative regulation of establishment of protein localization to mitochondrion


negative regulation of protein localization


positive regulation of adipose tissue development


positive regulation of protein catabolic process in the vacuole


response to phorbol 13-acetate 12-myristate


regulation of protein localization to chromosome, telomeric region


positive regulation of establishment of protein localization to telomere


positive regulation of telomerase RNA localization to Cajal body


negative regulation of establishment of protein localization


positive regulation of double-strand break repair via homologous recombination


negative regulation of vascular associated smooth muscle cell apoptotic process


regulation of protein localization to chromatin


positive regulation of DNA-templated DNA replication


negative regulation of cAMP-dependent protein kinase activity


regulation of epithelial cell differentiation involved in kidney development


positive regulation of epithelial cell differentiation involved in kidney development


regulation of synaptic vesicle clustering


positive regulation of ATP biosynthetic process


anterograde dendritic transport of neurotransmitter receptor complex


catechol-containing compound catabolic process


detection of stimulus involved in sensory perception of pain


medium-chain fatty-acyl-CoA metabolic process


mitochondrial electron transport, cytochrome c to oxygen


mitotic G1/S transition checkpoint signaling


myoblast fusion involved in skeletal muscle regeneration


negative regulation of chronic inflammatory response


positive regulation of apoptotic DNA fragmentation


positive regulation of CD4-positive, alpha-beta T cell proliferation


positive regulation of miRNA metabolic process


regulation of antifungal innate immune response


regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation


regulation of glucan biosynthetic process


regulation of matrix metallopeptidase secretion


extrinsic component of postsynaptic membrane


extrinsic component of synaptic membrane


protein complex involved in cell adhesion


TIM22 mitochondrial import inner membrane insertion complex


ATP-activated inward rectifier potassium channel activity


cysteine-type endopeptidase regulator activity involved in apoptotic process


general transcription initiation factor binding


glutathione disulfide oxidoreductase activity


nucleobase transmembrane transporter activity


oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen


phosphatidylinositol phosphate phosphatase activity


racemase and epimerase activity, acting on carbohydrates and derivatives


RNA polymerase II general transcription initiation factor binding


TFIIB-class transcription factor binding


TFIID-class transcription factor complex binding


Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) (Homo sapiens)


ADP signalling through P2Y purinoceptor 12 (Homo sapiens)


negative regulation of insulin secretion


AKT phosphorylates targets in the cytosol (Homo sapiens)


Alpha-protein kinase 1 signaling pathway (Homo sapiens)


Beta-catenin independent WNT signaling (Homo sapiens)


CD209 (DC-SIGN) signaling (Homo sapiens)


CD28 dependent Vav1 pathway (Homo sapiens)


Chemokine receptors bind chemokines (Homo sapiens)


Class B/2 (Secretin family receptors) (Homo sapiens)


Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding (Homo sapiens)


CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling (Homo sapiens)


Cross-presentation of particulate exogenous antigens (phagosomes) (Homo sapiens)


Defective Intrinsic Pathway for Apoptosis (Homo sapiens)


Disinhibition of SNARE formation (Homo sapiens)


Dopamine clearance from the synaptic cleft (Homo sapiens)


Dopamine Neurotransmitter Release Cycle (Homo sapiens)


Downstream signaling of activated FGFR1 (Homo sapiens)


Erythropoietin activates RAS (Homo sapiens)


FCERI mediated MAPK activation (Homo sapiens)


Folding of actin by CCT/TriC (Homo sapiens)


Formation of TC-NER Pre-Incision Complex (Homo sapiens)


Free fatty acids regulate insulin secretion (Homo sapiens)


FRS-mediated FGFR1 signaling (Homo sapiens)


FRS-mediated FGFR4 signaling (Homo sapiens)


G beta:gamma signalling through CDC42 (Homo sapiens)


G beta:gamma signalling through PI3Kgamma (Homo sapiens)


global genome nucleotide-excision repair


Glucagon-type ligand receptors (Homo sapiens)


regulation of generation of precursor metabolites and energy


Inwardly rectifying K+ channels (Homo sapiens)


IRAK2 mediated activation of TAK1 complex (Homo sapiens)


Metabolism of ingested SeMet, Sec, MeSec into H2Se (Homo sapiens)


Modulation by Mtb of host immune system (Homo sapiens)


Negative regulation of FGFR1 signaling (Homo sapiens)


Neurotransmitter receptors and postsynaptic signal transmission (Homo sapiens)


Norepinephrine Neurotransmitter Release Cycle (Homo sapiens)


Nucleotide Excision Repair (Homo sapiens)


Presynaptic function of Kainate receptors (Homo sapiens)


Prostacyclin signalling through prostacyclin receptor (Homo sapiens)


PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Homo sapiens)


Purinergic signaling in leishmaniasis infection (Homo sapiens)


Ras activation upon Ca2+ influx through NMDA receptor (Homo sapiens)


Reelin signalling pathway (Homo sapiens)


Regulation of PTEN localization (Homo sapiens)


Sema3A PAK dependent Axon repulsion (Homo sapiens)


Signaling by BRAF and RAF1 fusions (Homo sapiens)


Signaling by ERBB2 ECD mutants (Homo sapiens)


Signaling by FGFR4 in disease (Homo sapiens)


Signaling by KIT in disease (Homo sapiens)


Spry regulation of FGF signaling (Homo sapiens)


Synthesis of 12-eicosatetraenoic acid derivatives (Homo sapiens)


TICAM1-dependent activation of IRF3/IRF7 (Homo sapiens)


TICAM1,TRAF6-dependent induction of TAK1 complex (Homo sapiens)


TP53 Regulates Transcription of Caspase Activators and Caspases (Homo sapiens)


TP53 Regulates Transcription of DNA Repair Genes (Homo sapiens)


TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain (Homo sapiens)


TRAF6-mediated induction of TAK1 complex within TLR4 complex (Homo sapiens)


Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template (Homo sapiens)


Translocation of SLC2A4 (GLUT4) to the plasma membrane (Homo sapiens)


Transmission across Chemical Synapses (Homo sapiens)


VEGFR2 mediated cell proliferation (Homo sapiens)


low-density lipoprotein particle receptor catabolic process


WNT ligand biogenesis and trafficking (Homo sapiens)


WNT5A-dependent internalization of FZD4 (Homo sapiens)


very long-chain fatty acid metabolic process


regulation of T cell mediated cytotoxicity


positive regulation of cell-matrix adhesion


regulation of systemic arterial blood pressure by hormone


cell migration involved in sprouting angiogenesis


natural killer cell mediated immune response to tumor cell


T cell antigen processing and presentation


dendritic cell antigen processing and presentation


regulation of T-helper 1 type immune response


positive regulation of T-helper 1 type immune response


positive regulation of response to tumor cell


regulation of systemic arterial blood pressure by renin-angiotensin


transcription elongation by RNA polymerase II


SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition


unsaturated fatty acid biosynthetic process


regulation of calcium ion transport into cytosol


regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion


nuclear-transcribed mRNA catabolic process, deadenylation-independent decay


positive regulation of nervous system process


regulation of proteasomal ubiquitin-dependent protein catabolic process


positive regulation of type II interferon production


negative regulation of epinephrine secretion


negative regulation of protein sumoylation


positive regulation of mammary gland epithelial cell proliferation


nucleoside bisphosphate catabolic process


regulation of toll-like receptor 9 signaling pathway


protein localization to phagophore assembly site


negative regulation of fibroblast growth factor receptor signaling pathway


establishment of planar polarity of embryonic epithelium


very long-chain fatty acid catabolic process


positive regulation of canonical NF-kappaB signal transduction


positive regulation of skeletal muscle tissue regeneration


regulation of skeletal muscle tissue regeneration


negative regulation of glycolytic process


negative regulation of smooth muscle contraction


parasympathetic nervous system development


positive regulation of membrane protein ectodomain proteolysis


relaxation of vascular associated smooth muscle


inner ear receptor cell stereocilium organization


negative regulation of respiratory burst


positive regulation of type I interferon-mediated signaling pathway


developmental growth involved in morphogenesis


regulation of microtubule-based movement


negative regulation of small molecule metabolic process


intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress


establishment of protein localization to telomere


extracellular matrix constituent secretion


regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway


regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway


regulation of cell migration involved in sprouting angiogenesis


negative regulation of cell migration involved in sprouting angiogenesis


establishment of planar polarity involved in neural tube closure


positive regulation of the force of heart contraction


positive regulation of meiotic cell cycle phase transition


regulation of hematopoietic stem cell proliferation


regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway


negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway


regulation of RNA polymerase II regulatory region sequence-specific DNA binding


negative regulation of protein modification by small protein conjugation or removal


negative regulation of microglial cell activation


regulation of response to endoplasmic reticulum stress


regulation of DNA-templated transcription initiation


positive regulation of DNA-templated transcription initiation


regulation of cardiac muscle cell differentiation


positive regulation of cardiac muscle cell differentiation


regulation of mesenchymal stem cell differentiation


regulation of CD8-positive, alpha-beta T cell activation


regulation of unsaturated fatty acid biosynthetic process


positive regulation of unsaturated fatty acid biosynthetic process


glucose import in response to insulin stimulus


nucleotide-binding oligomerization domain containing 1 signaling pathway


positive regulation by symbiont of entry into host


positive regulation of fatty acid oxidation


positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway


positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway


positive regulation of toll-like receptor 9 signaling pathway


regulation of dendritic cell antigen processing and presentation


regulation of meiotic cell cycle phase transition


regulation of T cell mediated immune response to tumor cell


T cell mediated immune response to tumor cell


xenobiotic transport across blood-brain barrier


transferase complex, transferring phosphorus-containing groups


amide transmembrane transporter activity


ATPase-coupled lipid transmembrane transporter activity


core promoter sequence-specific DNA binding


histone H3K36 methyltransferase activity


long-chain fatty acid transmembrane transporter activity


mitochondrion targeting sequence binding


oxidoreductase activity, acting on peroxide as acceptor


ubiquitin-like protein conjugating enzyme activity


Butyrophilin (BTN) family interactions (Homo sapiens)


Defective CHST14 causes EDS, musculocontractural type (Homo sapiens)


Defective CHST3 causes SEDCJD (Homo sapiens)


Defective CHSY1 causes TPBS (Homo sapiens)


FGFRL1 modulation of FGFR1 signaling (Homo sapiens)


mRNA decay by 3' to 5' exoribonuclease (Homo sapiens)


regulation of cytokine-mediated signaling pathway


RUNX3 regulates WNT signaling (Homo sapiens)


Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Homo sapiens)


TP53 Regulates Transcription of Cell Cycle Genes (Homo sapiens)


somatic diversification of immune receptors


lymphoid progenitor cell differentiation


somatic diversification of T cell receptor genes


negative regulation of T cell mediated immunity


negative regulation of type 2 immune response


renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure


transforming growth factor beta receptor signaling pathway


gamma-aminobutyric acid signaling pathway


negative regulation of neuroblast proliferation


negative regulation of cell-substrate adhesion


peptidyl-arginine methylation, to asymmetrical-dimethyl arginine


positive regulation of protein autophosphorylation


regulation of endodeoxyribonuclease activity


negative regulation of chondrocyte differentiation


negative regulation of proteasomal ubiquitin-dependent protein catabolic process


negative regulation of interleukin-4 production


positive regulation of chemokine production


regulation of toll-like receptor 2 signaling pathway


protein folding in endoplasmic reticulum


regulation of Rho protein signal transduction


CD4-positive, alpha-beta T cell activation


negative regulation of JUN kinase activity


regulation of lymphocyte differentiation


positive regulation of lymphocyte differentiation


negative regulation of fatty acid metabolic process


regulation of Ras protein signal transduction


positive regulation of alpha-beta T cell activation


regulation of alpha-beta T cell differentiation


positive regulation of alpha-beta T cell differentiation


regulation of gamma-delta T cell activation


negative regulation of protein export from nucleus


antigen processing and presentation of peptide antigen


regulation of isotype switching to IgE isotypes


negative regulation of B cell activation


chaperone-mediated protein complex assembly


regulation of cytosolic calcium ion concentration


positive regulation of post-transcriptional gene silencing


negative regulation of SMAD protein signal transduction


growth hormone receptor signaling pathway via JAK-STAT


calcium ion transmembrane transport via high voltage-gated calcium channel


actin polymerization-dependent cell motility


poly(A)-dependent snoRNA 3'-end processing


cellular response to laminar fluid shear stress


organism emergence from protective structure


negative regulation of protein serine/threonine kinase activity


proximal/distal pattern formation involved in nephron development


intrinsic apoptotic signaling pathway by p53 class mediator


regulation of cellular response to stress


adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process


regulation of postsynaptic neurotransmitter receptor internalization


regulation of presynaptic membrane potential


regulation of presynaptic cytosolic calcium ion concentration


negative regulation of cold-induced thermogenesis


positive regulation of voltage-gated calcium channel activity


regulation of high voltage-gated calcium channel activity


regulation of receptor localization to synapse


negative regulation of regulated secretory pathway


positive regulation of blood circulation


regulation of potassium ion export across plasma membrane


positive regulation of chromatin organization


negative regulation of ubiquitin-dependent protein catabolic process


CD4-positive, alpha-beta T cell differentiation


external encapsulating structure organization


negative regulation of chemokine (C-X-C motif) ligand 2 production


negative regulation of IRE1-mediated unfolded protein response


positive regulation of epithelial tube formation


positive regulation of mitotic cell cycle spindle assembly checkpoint


positive regulation of nitric oxide metabolic process


regulation of lens fiber cell differentiation


regulation of mitotic cell cycle spindle assembly checkpoint


regulation of pattern recognition receptor signaling pathway


somatic diversification of immunoglobulins


somatic diversification of immunoglobulins involved in immune response


intracellularly gated calcium channel activity


catalytic activity, acting on a nucleic acid


cysteine-type endopeptidase inhibitor activity involved in apoptotic process


delayed rectifier potassium channel activity


DNA-(apurinic or apyrimidinic site) endonuclease activity


intracellularly calcium-gated chloride channel activity


intracellularly ligand-gated monoatomic ion channel activity


metal ion transmembrane transporter activity


oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor


passive transmembrane transporter activity


platelet-derived growth factor receptor binding


protein-arginine omega-N asymmetric methyltransferase activity


sodium ion transmembrane transporter activity


transferase activity, transferring one-carbon groups


ubiquitin-like protein conjugating enzyme binding


Activation of NOXA and translocation to mitochondria (Homo sapiens)


ATF6 (ATF6-alpha) activates chaperone genes (Homo sapiens)


Erythrocytes take up carbon dioxide and release oxygen (Homo sapiens)


Erythrocytes take up oxygen and release carbon dioxide (Homo sapiens)


FGFR1b ligand binding and activation (Homo sapiens)


HDR through Homologous Recombination (HRR) (Homo sapiens)


HDR through Single Strand Annealing (SSA) (Homo sapiens)


Homologous DNA Pairing and Strand Exchange (Homo sapiens)


Inactivation of CDC42 and RAC1 (Homo sapiens)


Interleukin-2 family signaling (Homo sapiens)


Nef and signal transduction (Homo sapiens)


Nonsense-Mediated Decay (NMD) (Homo sapiens)


Regulation of cytoskeletal remodeling and cell spreading by IPP complex components (Homo sapiens)


RHO GTPases Activate Formins (Homo sapiens)


RHO GTPases activate PAKs (Homo sapiens)


RUNX3 regulates BCL2L11 (BIM) transcription (Homo sapiens)


Sodium-coupled sulphate, di- and tri-carboxylate transporters (Homo sapiens)


SUMOylation of DNA damage response and repair proteins (Homo sapiens)


TNFs bind their physiological receptors (Homo sapiens)


TRAF3-dependent IRF activation pathway (Homo sapiens)


Trafficking of myristoylated proteins to the cilium (Homo sapiens)


Triglyceride biosynthesis (Homo sapiens)


Vasopressin-like receptors (Homo sapiens)


T cell activation involved in immune response


chondrocyte differentiation involved in endochondral bone morphogenesis


growth plate cartilage chondrocyte differentiation


cotranslational protein targeting to membrane


SRP-dependent cotranslational protein targeting to membrane, translocation


adenylate cyclase-activating dopamine receptor signaling pathway


branched-chain amino acid catabolic process


post-transcriptional regulation of gene expression


positive regulation of cardiac muscle adaptation


positive regulation of neuron projection development


protein O-linked glycosylation via serine


protein O-linked glycosylation via threonine


central nervous system projection neuron axonogenesis


central nervous system neuron differentiation


central nervous system neuron development


central nervous system neuron axonogenesis


regulation of opsin-mediated signaling pathway


positive regulation of bone mineralization


regulation of nucleobase-containing compound transport


positive regulation of nucleobase-containing compound transport


sequestering of extracellular ligand from receptor


neuron intrinsic apoptotic signaling pathway in response to oxidative stress


signal transduction in response to DNA damage


negative regulation of neuron apoptotic process


modification-dependent macromolecule catabolic process


mitotic DNA integrity checkpoint signaling


modulation by host of viral genome replication


positive regulation of epidermal cell differentiation


positive regulation of epidermis development


positive regulation of hormone biosynthetic process


regulation of oligodendrocyte differentiation


negative regulation of oligodendrocyte differentiation


detection of temperature stimulus involved in sensory perception


detection of mechanical stimulus involved in sensory perception of pain


maternal process involved in female pregnancy


phospholipase C-activating dopamine receptor signaling pathway


cartilage development involved in endochondral bone morphogenesis


negative regulation of androgen receptor signaling pathway


positive regulation of myeloid leukocyte cytokine production involved in immune response


microtubule organizing center localization


regulation of interleukin-6-mediated signaling pathway


phosphatidylserine exposure on apoptotic cell surface


transforming growth factor beta production


positive regulation of cell proliferation in bone marrow


mesenchymal cell differentiation involved in kidney development


metanephric mesenchymal cell differentiation


postsynaptic density protein 95 clustering


learned vocalization behavior or vocal learning


presynaptic modulation of chemical synaptic transmission


extracellular regulation of signal transduction


positive regulation of NLRP3 inflammasome complex assembly


regulation of glutamate receptor signaling pathway


neural crest cell migration involved in autonomic nervous system development


negative regulation of cell cycle phase transition


cellular response to reactive nitrogen species


regulation of cell cycle G2/M phase transition


negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway


regulation of adherens junction organization


positive regulation of chromosome separation


regulation of natural killer cell chemotaxis


negative regulation of extrinsic apoptotic signaling pathway


branched-chain amino acid metabolic process


calcium ion import into sarcoplasmic reticulum


catechol-containing compound metabolic process


chromosome attachment to the nuclear envelope


double-strand break repair involved in meiotic recombination


maintenance of protein location in extracellular region


negative regulation of serotonin secretion


negative regulation of syncytium formation by plasma membrane fusion


positive regulation of clathrin-dependent endocytosis


positive regulation of metaphase/anaphase transition of cell cycle


positive regulation of RNA export from nucleus


positive regulation of steroid hormone biosynthetic process


proteasome-mediated ubiquitin-dependent protein catabolic process


protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway


pyrimidine ribonucleotide catabolic process


regulation of complement-dependent cytotoxicity


regulation of forebrain neuron differentiation


regulation of protein K48-linked ubiquitination


retrograde transport, vesicle recycling within Golgi


G protein-coupled opsin signaling pathway


vesicle targeting, rough ER to cis-Golgi


endoplasmic reticulum-Golgi intermediate compartment membrane


proteasome core complex, alpha-subunit complex


O-acyl-L-carnitine transmembrane transporter activity


C4-dicarboxylate transmembrane transporter activity


dopamine neurotransmitter receptor activity


extracellular matrix structural constituent conferring tensile strength


L-alanine transmembrane transporter activity


mechanosensitive monoatomic ion channel activity


mitogen-activated protein kinase binding


proton transmembrane transporter activity


quaternary ammonium group transmembrane transporter activity


voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels


Activated NTRK2 signals through FYN (Homo sapiens)


Activation of PUMA and translocation to mitochondria (Homo sapiens)


Assembly and cell surface presentation of NMDA receptors (Homo sapiens)


Assembly of collagen fibrils and other multimeric structures (Homo sapiens)


Class C/3 (Metabotropic glutamate/pheromone receptors) (Homo sapiens)


Collagen biosynthesis and modifying enzymes (Homo sapiens)


Collagen chain trimerization (Homo sapiens)


COPI-independent Golgi-to-ER retrograde traffic (Homo sapiens)


CRMPs in Sema3A signaling (Homo sapiens)


Cyclin A/B1/B2 associated events during G2/M transition (Homo sapiens)


Diseases associated with surfactant metabolism (Homo sapiens)


ER to Golgi Anterograde Transport (Homo sapiens)


G1/S-Specific Transcription (Homo sapiens)


Golgi-to-ER retrograde transport (Homo sapiens)


Host Interactions of HIV factors (Homo sapiens)


Integrin cell surface interactions (Homo sapiens)


Intra-Golgi and retrograde Golgi-to-ER traffic (Homo sapiens)


Loss of function of MECP2 in Rett syndrome (Homo sapiens)


MECP2 regulates neuronal receptors and channels (Homo sapiens)


MET activates PTK2 signaling (Homo sapiens)


NCAM signaling for neurite out-growth (Homo sapiens)


Nef mediated downregulation of MHC class I complex cell surface expression (Homo sapiens)


Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters (Homo sapiens)


double-strand break repair via nonhomologous end joining


Notch-HLH transcription pathway (Homo sapiens)


NOTCH1 Intracellular Domain Regulates Transcription (Homo sapiens)


NOTCH4 Intracellular Domain Regulates Transcription (Homo sapiens)


NR1H2 & NR1H3 regulate gene expression linked to lipogenesis (Homo sapiens)


Post-translational protein modification (Homo sapiens)


Pre-NOTCH Expression and Processing (Homo sapiens)


Proton-coupled monocarboxylate transport (Homo sapiens)


purine ribonucleoside monophosphate biosynthetic process


Retrograde neurotrophin signalling (Homo sapiens)


Sealing of the nuclear envelope (NE) by ESCRT-III (Homo sapiens)


Sensing of DNA Double Strand Breaks (Homo sapiens)


Sensory perception of taste (Homo sapiens)


Signaling by TGF-beta Receptor Complex (Homo sapiens)


SUMOylation of transcription cofactors (Homo sapiens)


Synthesis of PIPs at the late endosome membrane (Homo sapiens)


TFAP2 (AP-2) family regulates transcription of growth factors and their receptors (Homo sapiens)


The role of Nef in HIV-1 replication and disease pathogenesis (Homo sapiens)


Transcription of E2F targets under negative control by DREAM complex (Homo sapiens)


Vesicle-mediated transport (Homo sapiens)


intracerebral hemorrhage

biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing


regulation of natural killer cell mediated immunity


regulation of glycogen catabolic process


positive regulation of phosphatase activity


negative regulation of cell-cell adhesion


regulation of myeloid dendritic cell activation


establishment or maintenance of cytoskeleton polarity


regulation of microtubule depolymerization


negative regulation of interferon-alpha production


negative regulation of interleukin-13 production


negative regulation of interleukin-5 production


cellular anatomical entity morphogenesis


positive regulation of catecholamine secretion


CD8-positive, alpha-beta T cell activation


regulation of translation in response to stress


regulation of translational initiation in response to stress


negative regulation of T cell differentiation


positive regulation of T-helper 1 cell differentiation


positive regulation of neurotrophin TRK receptor signaling pathway


microtubule nucleation by microtubule organizing center


establishment of mitochondrion localization


dichotomous subdivision of an epithelial terminal unit


neurotransmitter loading into synaptic vesicle


regulation of modification of postsynaptic structure


regulation of execution phase of apoptosis


positive regulation of protein acetylation


positive regulation of protein monoubiquitination


positive regulation of myoblast proliferation


negative regulation of CD8-positive, alpha-beta T cell activation


positive regulation of extrinsic apoptotic signaling pathway in absence of ligand


glucosamine-containing compound catabolic process


host-mediated perturbation of symbiont process


negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation


platelet activating factor metabolic process


positive regulation of miRNA catabolic process


regulation of mitochondrial gene expression


calcium-independent phospholipase A2 activity


excitatory extracellular ligand-gated monoatomic ion channel activity


oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water


single-stranded DNA 3'-5' DNA exonuclease activity


Activation of the TFAP2 (AP-2) family of transcription factors (Homo sapiens)


Anchoring fibril formation (Homo sapiens)


Apoptotic cleavage of cellular proteins (Homo sapiens)


Aryl hydrocarbon receptor signalling (Homo sapiens)


Binding and Uptake of Ligands by Scavenger Receptors (Homo sapiens)


Crosslinking of collagen fibrils (Homo sapiens)


Displacement of DNA glycosylase by APEX1 (Homo sapiens)


Formation of RNA Pol II elongation complex  (Homo sapiens)


G2/M DNA replication checkpoint (Homo sapiens)


HIV Transcription Elongation (Homo sapiens)


Interaction With Cumulus Cells And The Zona Pellucida (Homo sapiens)


MAPK targets/ Nuclear events mediated by MAP kinases (Homo sapiens)


Metabolism of amine-derived hormones (Homo sapiens)


Negative regulation of activity of TFAP2 (AP-2) family transcription factors (Homo sapiens)


Scavenging by Class A Receptors (Homo sapiens)


TRAF6 mediated IRF7 activation (Homo sapiens)


Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 (Homo sapiens)


regulation of transcription by RNA polymerase II


thyroid hormone receptor signaling pathway


T cell differentiation involved in immune response


positive regulation of immunoglobulin production


negative regulation of leukocyte migration


negative regulation of leukocyte chemotaxis


positive regulation of production of molecular mediator of immune response


regulation of very-low-density lipoprotein particle remodeling


C-terminal protein amino acid modification


DNA damage response, signal transduction by p53 class mediator


negative regulation of telomere maintenance


regulation of aldosterone metabolic process


positive regulation of interleukin-13 production


negative regulation of mast cell activation


negative regulation of mast cell activation involved in immune response


mitochondrial proton-transporting ATP synthase complex assembly


positive regulation of amide metabolic process


maintenance of protein localization in endoplasmic reticulum


CD4-positive, alpha-beta T cell cytokine production


positive regulation of T cell proliferation


positive regulation of leukocyte degranulation


positive regulation of memory T cell differentiation


regulation of DNA damage response, signal transduction by p53 class mediator


regulation of adenylate cyclase activity


positive regulation of adenylate cyclase activity


positive regulation of smoothened signaling pathway


regulation of RNA polymerase II transcription preinitiation complex assembly


development of primary female sexual characteristics


regulation of viral entry into host cell


regulation of alpha-beta T cell activation


positive regulation of release of sequestered calcium ion into cytosol


biological process involved in interaction with host


negative regulation of cardiac muscle tissue growth


camera-type eye photoreceptor cell differentiation


positive regulation of SMAD protein signal transduction


regulation of androgen receptor signaling pathway


ciliary neurotrophic factor-mediated signaling pathway


positive regulation of leukocyte proliferation


monocarboxylic acid biosynthetic process


signal transduction by p53 class mediator


pyrimidine-containing compound transmembrane transport


regulation of protein kinase C signaling


positive regulation of protein kinase C signaling


regulation of translation at synapse, modulating synaptic transmission


negative regulation of execution phase of apoptosis


primary amino compound biosynthetic process


negative regulation of signal transduction by p53 class mediator


positive regulation of signal transduction by p53 class mediator


regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator


regulation of intrinsic apoptotic signaling pathway by p53 class mediator


positive regulation of leukocyte cell-cell adhesion


regulation of calcium ion transmembrane transport


regulation of leukocyte tethering or rolling


positive regulation of regulated secretory pathway


regulation of reactive oxygen species biosynthetic process


regulation of plasma membrane organization


positive regulation of monoatomic anion transport


positive regulation of IRE1-mediated unfolded protein response


regulation of bile acid metabolic process


regulation of ubiquitin protein ligase activity


negative regulation of ubiquitin protein ligase activity


regulation of leukocyte adhesion to vascular endothelial cell


negative regulation of macrophage migration


negative regulation of cell-cell adhesion mediated by cadherin


antigen processing and presentation of exogenous antigen


antigen processing and presentation of exogenous peptide antigen


antigen processing and presentation of exogenous peptide antigen via MHC class II


G1 to G0 transition involved in cell differentiation


hematopoietic stem cell migration to bone marrow


keratan sulfate proteoglycan metabolic process


negative regulation of cell adhesion molecule production


negative regulation of nucleotide metabolic process


pigment metabolic process involved in pigmentation


positive regulation of blood-brain barrier permeability


positive regulation of CD4-positive, alpha-beta T cell differentiation


regulation of blood-brain barrier permeability


regulation of mitochondrial membrane permeability


snRNA transcription by RNA polymerase II


aminoacyl-tRNA synthetase multienzyme complex


clathrin-coated endocytic vesicle membrane


5-alpha-androstane-3-beta,17-beta-diol dehydrogenase (NADP+) activity


acetylcholine receptor inhibitor activity


beta-galactoside (CMP) alpha-2,3-sialyltransferase activity


catalytic activity, acting on a glycoprotein


estradiol 17-beta-dehydrogenase [NAD(P)+] activity


glutamate-gated calcium ion channel activity


inorganic diphosphate phosphatase activity


inositol trisphosphate phosphatase activity


intramolecular oxidoreductase activity, interconverting aldoses and ketoses


intramolecular oxidoreductase activity, transposing C=C bonds


ligase activity, forming phosphoric ester bonds


manganese ion transmembrane transporter activity


all-trans-retinol dehydrogenase (NAD+) activity


nucleoside transmembrane transporter activity


oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor


oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen


oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen


phosphatidylinositol phosphate 5-phosphatase activity


retinoic acid-responsive element binding


steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor


testosterone 17-beta-dehydrogenase (NADP+) activity


testosterone dehydrogenase [NAD(P)+] activity


testosterone dehydrogenase (NAD+) activity


ubiquitin-protein transferase regulator activity


Activation of gene expression by SREBF (SREBP) (Homo sapiens)


ADP signalling through P2Y purinoceptor 1 (Homo sapiens)


Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Homo sapiens)


Arachidonate production from DAG (Homo sapiens)


Asparagine N-linked glycosylation (Homo sapiens)


Assembly Of The HIV Virion (Homo sapiens)


positive regulation of intrinsic apoptotic signaling pathway


Calcineurin activates NFAT (Homo sapiens)


Cytochrome P450 - arranged by substrate type (Homo sapiens)


Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Homo sapiens)


HDMs demethylate histones (Homo sapiens)


Interleukin-4 and Interleukin-13 signaling (Homo sapiens)


keratan sulfate proteoglycan biosynthetic process


Metal ion SLC transporters (Homo sapiens)


N-glycan antennae elongation in the medial/trans-Golgi (Homo sapiens)


Neurotransmitter clearance (Homo sapiens)


NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux (Homo sapiens)


Organic cation/anion/zwitterion transport (Homo sapiens)


Phase I - Functionalization of compounds (Homo sapiens)


Pre-NOTCH Processing in Golgi (Homo sapiens)


Release of apoptotic factors from the mitochondria (Homo sapiens)


Release of Hh-Np from the secreting cell (Homo sapiens)


multicellular organismal reproductive process


Retrograde transport at the Trans-Golgi-Network (Homo sapiens)


Signaling by the B Cell Receptor (BCR) (Homo sapiens)


Synthesis of bile acids and bile salts via 27-hydroxycholesterol (Homo sapiens)


Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Homo sapiens)


Thromboxane signalling through TP receptor (Homo sapiens)


Transport of bile salts and organic acids, metal ions and amine compounds (Homo sapiens)


Transport to the Golgi and subsequent modification (Homo sapiens)


ribosomal small subunit export from nucleus


positive regulation of neurotransmitter secretion


transcription elongation by RNA polymerase I


protein quality control for misfolded or incompletely synthesized proteins


establishment or maintenance of cell polarity


actin polymerization or depolymerization


positive regulation of sodium ion transport


cellular response to reactive oxygen species


cellular response to topologically incorrect protein


modified amino acid biosynthetic process


negative regulation of insulin-like growth factor receptor signaling pathway


transcription initiation-coupled chromatin remodeling


negative regulation of collateral sprouting


positive regulation of ubiquitin-protein transferase activity


regulation of neurotransmitter transport


regulation of synaptic transmission, glutamatergic


positive regulation of attachment of spindle microtubules to kinetochore


regulation of attachment of spindle microtubules to kinetochore


positive regulation of uterine smooth muscle contraction


protein modification by small protein conjugation or removal


positive regulation of deacetylase activity


positive regulation of mitochondrial fission


establishment of protein localization to membrane


positive regulation of protein deacetylation


negative regulation of plasma membrane bounded cell projection assembly


positive regulation of RIG-I signaling pathway


negative regulation of voltage-gated calcium channel activity


negative regulation of organelle assembly


regulation of sodium ion transmembrane transport


positive regulation of sodium ion transmembrane transport


negative regulation of autophagosome assembly


negative regulation of receptor signaling pathway via STAT


positive regulation of Arp2/3 complex-mediated actin nucleation


regulation of double-strand break repair via nonhomologous end joining


chemokine (C-X-C motif) ligand 1 production


cyclic-GMP-AMP transmembrane import across plasma membrane


negative regulation of translational elongation


regulation of synaptic vesicle exocytosis


clathrin-sculpted gamma-aminobutyric acid transport vesicle


clathrin-sculpted monoamine transport vesicle


proteasome core complex, beta-subunit complex


3-beta-hydroxy-Delta5-steroid dehydrogenase (NAD+) activity


bile acid transmembrane transporter activity


inositol bisphosphate phosphatase activity


isocitrate dehydrogenase [NAD(P)+] activity


RNA polymerase II C-terminal domain phosphoserine binding


ubiquitin-protein transferase activator activity


positive regulation of type I interferon production


Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) (Homo sapiens)


Defective CHST6 causes MCDC1 (Homo sapiens)


Defective GALNT3 causes HFTC (Homo sapiens)


Elevation of cytosolic Ca2+ levels (Homo sapiens)


Incretin synthesis, secretion, and inactivation (Homo sapiens)


IRF3-mediated induction of type I IFN (Homo sapiens)


regulation of myeloid cell differentiation


STING mediated induction of host immune responses (Homo sapiens)


sodium-independent organic anion transport


nuclear-transcribed mRNA catabolic process, nonsense-mediated decay


positive regulation of cytokine production


positive regulation of T cell mediated cytotoxicity


antigen processing and presentation of peptide antigen via MHC class Ib


inflammatory response to antigenic stimulus


regulation of acute inflammatory response


positive regulation of acute inflammatory response


positive regulation of lymphocyte mediated immunity


regulation of inflammatory response to antigenic stimulus


mitochondrial electron transport, ubiquinol to cytochrome c


intracellular monoatomic ion homeostasis


activation-induced cell death of T cells


positive regulation of calcium ion transport into cytosol


programmed cell death involved in cell development


skeletal muscle satellite cell differentiation


negative regulation of smooth muscle cell migration


energy derivation by oxidation of organic compounds


calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules


calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules


intracellular receptor signaling pathway


polarized epithelial cell differentiation


regulation of microtubule polymerization


negative regulation of protein-containing complex assembly


negative regulation of protein polymerization


positive regulation of gonadotropin secretion


somite rostral/caudal axis specification


negative regulation of interferon-beta production


negative regulation of interleukin-17 production


positive regulation of interleukin-12 production


transforming growth factor beta1 production


positive regulation of transforming growth factor beta1 production


regulation of luteinizing hormone secretion


positive regulation of osteoblast proliferation


positive regulation of homotypic cell-cell adhesion


regulation of toll-like receptor 4 signaling pathway


substrate adhesion-dependent cell spreading


positive regulation of monoatomic ion transmembrane transport


bone mineralization involved in bone maturation


regulation of multicellular organism growth


DNA damage response, signal transduction resulting in transcription


CD4-positive or CD8-positive, alpha-beta T cell lineage commitment


positive regulation of neuron apoptotic process


regulation of monoatomic anion transport


negative regulation by host of viral process


positive regulation of keratinocyte differentiation


regulation of melanocyte differentiation


positive regulation of melanocyte differentiation


positive regulation of myeloid cell differentiation


regulation of erythrocyte differentiation


positive regulation of glial cell differentiation


negative regulation of centriole replication


insulin-like growth factor receptor signaling pathway


neurotrophin TRK receptor signaling pathway


positive regulation of synaptic transmission


positive regulation of developmental process


negative regulation of multicellular organismal process


regulation of release of sequestered calcium ion into cytosol


positive regulation of calcium ion transport


positive regulation of respiratory burst


regulation of phosphatidylinositol dephosphorylation


regulation of glycogen metabolic process


cellular response to mechanical stimulus


metanephric nephron tubule epithelial cell differentiation


establishment of protein localization to organelle


negative regulation of inclusion body assembly


positive regulation of extracellular matrix disassembly


positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway


positive regulation of substrate adhesion-dependent cell spreading


negative regulation of hydrogen peroxide-mediated programmed cell death


positive regulation of amyloid-beta formation


regulation of extrinsic apoptotic signaling pathway via death domain receptors


negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway


regulation of lamellipodium organization


positive regulation of amyloid precursor protein catabolic process


regulation of glycoprotein metabolic process


regulation of extracellular matrix organization


negative regulation of reactive oxygen species biosynthetic process


regulation of epithelial cell apoptotic process


positive regulation of calcium ion transmembrane transport


regulation of apoptotic process involved in development


positive regulation of vascular endothelial cell proliferation


positive regulation of endothelial cell apoptotic process


negative regulation of cardiac muscle cell differentiation


positive regulation of integrin-mediated signaling pathway


positive regulation of interleukin-1 alpha production


protection from natural killer cell mediated cytotoxicity


regulation of skeletal muscle cell proliferation


regulation of transforming growth factor beta1 production


ATP-binding cassette (ABC) transporter complex


NLS-dependent protein nuclear import complex


calcium/calmodulin-dependent protein kinase activity


DNA endonuclease activity, producing 5'-phosphomonoesters


extracellular matrix structural constituent


L-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor


protein serine/threonine kinase activity


protein serine/threonine/tyrosine kinase activity


proton-transporting ATP synthase activity, rotational mechanism


signaling receptor complex adaptor activity


tumor necrosis factor receptor superfamily binding


voltage-gated calcium channel activity involved in cardiac muscle cell action potential


B-WICH complex positively regulates rRNA expression (Homo sapiens)


CaMK IV-mediated phosphorylation of CREB (Homo sapiens)


Caspase activation via Death Receptors in the presence of ligand (Homo sapiens)


Caspase activation via extrinsic apoptotic signalling pathway (Homo sapiens)


CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde (Homo sapiens)


EPHB-mediated forward signaling (Homo sapiens)


Estrogen-dependent gene expression (Homo sapiens)


FGFR1 mutant receptor activation (Homo sapiens)


Formation of the Early Elongation Complex (Homo sapiens)


GLI proteins bind promoters of Hh responsive genes to promote transcription (Homo sapiens)


HIV Transcription Initiation (Homo sapiens)


IkBA variant leads to EDA-ID (Homo sapiens)


Interleukin-6 family signaling (Homo sapiens)


IRF3 mediated activation of type 1 IFN (Homo sapiens)


Phosphate bond hydrolysis by NUDT proteins (Homo sapiens)


POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation (Homo sapiens)


Regulation of RUNX1 Expression and Activity (Homo sapiens)


Regulation of TP53 Activity through Methylation (Homo sapiens)


regulation of eIF2 alpha phosphorylation by heme


RNA Polymerase I Transcription Initiation (Homo sapiens)


termination of RNA polymerase I transcription


Role of phospholipids in phagocytosis (Homo sapiens)


Signaling by TGFB family members (Homo sapiens)


TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation (Homo sapiens)


Transcription of the HIV genome (Homo sapiens)


Transcriptional Regulation by MECP2 (Homo sapiens)


ZBP1(DAI) mediated induction of type I IFNs (Homo sapiens)


tolerance induction dependent upon immune response


regulation of chronic inflammatory response


negative regulation of inflammatory response to antigenic stimulus


regulation of extracellular matrix disassembly


positive regulation of epithelial to mesenchymal transition


regulation of calcium ion-dependent exocytosis


positive regulation of B cell proliferation


negative regulation of mRNA 3'-end processing


positive regulation of interleukin-18 production


regulation of DNA-templated transcription elongation


positive regulation of dopamine secretion


regulation of mesodermal cell fate specification


positive regulation of insulin-like growth factor receptor signaling pathway


negative regulation of neuron differentiation


negative regulation of activated T cell proliferation


regulation of skeletal muscle tissue development


positive regulation of B cell activation


branching involved in prostate gland morphogenesis


canonical Wnt signaling pathway involved in heart development


regulation of cardiac epithelial to mesenchymal transition


negative regulation of mononuclear cell migration


minus-end-directed organelle transport along microtubule


apoptotic process involved in development


negative regulation of tubulin deacetylation


regulation of midbrain dopaminergic neuron differentiation


positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation


regulation of membrane repolarization during ventricular cardiac muscle cell action potential


positive regulation of Wnt signaling pathway, planar cell polarity pathway


negative regulation of DNA-templated DNA replication


negative regulation of lymphocyte migration


negative regulation of transcription regulatory region DNA binding


positive regulation of CD8-positive, alpha-beta T cell activation


proton motive force-driven ATP synthesis


gephyrin clustering involved in postsynaptic density assembly


negative regulation of collagen metabolic process


positive regulation of cardiac epithelial to mesenchymal transition


positive regulation of protein neddylation


positive regulation of synaptic vesicle exocytosis


extrinsic component of mitochondrial inner membrane


insulin-like growth factor binding protein complex


protein complex involved in cell-matrix adhesion


calcium ion transmembrane transporter activity


complement component C1q complex binding


dehydroascorbic acid transmembrane transporter activity


general transcription initiation factor activity


hydrolase activity, hydrolyzing O-glycosyl compounds


oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor


oxidoreductase activity, acting on diphenols and related substances as donors


RNA polymerase II general transcription initiation factor activity


tRNA (cytidine) methyltransferase activity


vitamin transmembrane transporter activity


voltage-gated monoatomic anion channel activity


zinc ion transmembrane transporter activity


Activation of Matrix Metalloproteinases (Homo sapiens)


C-type lectin receptors (CLRs) (Homo sapiens)


CLEC7A (Dectin-1) signaling (Homo sapiens)


Defective C1GALT1C1 causes TNPS (Homo sapiens)


DEx/H-box helicases activate type I IFN and inflammatory cytokines production  (Homo sapiens)


EGFR interacts with phospholipase C-gamma (Homo sapiens)


GPVI-mediated activation cascade (Homo sapiens)


Initial triggering of complement (Homo sapiens)


Loss of Function of SMAD2/3 in Cancer (Homo sapiens)


Mitotic Metaphase and Anaphase (Homo sapiens)


RHO GTPases activate PKNs (Homo sapiens)


RIP-mediated NFkB activation via ZBP1 (Homo sapiens)


regulation of keratinocyte differentiation


RUNX2 regulates bone development (Homo sapiens)


Signaling by Insulin receptor (Homo sapiens)


Signaling by TGF-beta Receptor Complex in Cancer (Homo sapiens)


TGF-beta receptor signaling activates SMADs (Homo sapiens)


The phototransduction cascade (Homo sapiens)


TNFR2 non-canonical NF-kB pathway (Homo sapiens)


TP53 Regulates Transcription of Cell Death Genes (Homo sapiens)


Ub-specific processing proteases (Homo sapiens)


WNT5A-dependent internalization of FZD2, FZD5 and ROR2 (Homo sapiens)


positive regulation of defense response to virus by host


B cell proliferation involved in immune response


regulation of response to biotic stimulus


negative regulation of extracellular matrix disassembly


positive regulation of macrophage chemotaxis


negative regulation of peptidyl-threonine phosphorylation


peripheral nervous system axon regeneration


ventral spinal cord interneuron differentiation


negative regulation of protein modification process


negative regulation of protein autophosphorylation


positive regulation of interferon-alpha production


positive regulation of interleukin-2 production


positive regulation of interleukin-23 production


positive regulation of interleukin-6 production


regulation of polysaccharide metabolic process


regulation of homotypic cell-cell adhesion


establishment of mitotic spindle localization


antigen processing and presentation of exogenous peptide antigen via MHC class I


positive regulation of B cell differentiation


positive regulation of endothelial cell differentiation


positive regulation of erythrocyte differentiation


positive regulation of G protein-coupled receptor signaling pathway


negative regulation of mitotic cell cycle


regulation by virus of viral protein levels in host cell


regulation of defense response to virus by host


positive regulation of Fc receptor mediated stimulatory signaling pathway


negative regulation of glycogen metabolic process


cellular response to temperature stimulus


regulation of smooth muscle cell chemotaxis


regulation of inflammatory response to wounding


negative regulation of muscle tissue development


microtubule cytoskeleton organization involved in mitosis


regulation of dendritic spine maintenance


negative regulation of extracellular matrix organization


regulation of inorganic anion transmembrane transport


regulation of neuromuscular junction development


regulation of glycogen (starch) synthase activity


positive regulation of glycogen (starch) synthase activity


positive regulation of AMPA receptor activity


negative regulation of double-strand break repair via nonhomologous end joining


cell fate commitment involved in pattern specification


negative regulation of muscle organ development


positive regulation of microtubule nucleation


positive regulation of neutrophil extravasation


positive regulation of retinoic acid receptor signaling pathway


regulation of defense response to fungus


regulation of focal adhesion disassembly


regulation of mitochondrial RNA catabolic process


condensed chromosome, centromeric region


proton-transporting two-sector ATPase complex


proton-transporting two-sector ATPase complex, proton-transporting domain


proton-transporting V-type ATPase complex


proton-transporting V-type ATPase, V0 domain


vacuolar proton-transporting V-type ATPase, V0 domain


adenyl-nucleotide exchange factor activity


G protein-coupled acetylcholine receptor activity


hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides


hydrolase activity, acting on ether bonds


minus-end-directed microtubule motor activity


oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor


protein tyrosine kinase activator activity


rRNA (cytosine) methyltransferase activity


type I transforming growth factor beta receptor binding


Aberrant regulation of mitotic exit in cancer due to RB1 defects (Homo sapiens)


APC/C:Cdc20 mediated degradation of Cyclin B (Homo sapiens)


APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Homo sapiens)


APC/C-mediated degradation of cell cycle proteins (Homo sapiens)


Condensation of Prophase Chromosomes (Homo sapiens)


Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase (Homo sapiens)


COPI-mediated anterograde transport (Homo sapiens)


Deactivation of the beta-catenin transactivating complex (Homo sapiens)


Diseases of mitotic cell cycle (Homo sapiens)


Erythropoietin activates Phosphoinositide-3-kinase (PI3K) (Homo sapiens)


Mitotic Spindle Checkpoint (Homo sapiens)


Nef Mediated CD4 Down-regulation (Homo sapiens)


Neurotoxicity of clostridium toxins (Homo sapiens)


NOTCH2 Activation and Transmission of Signal to the Nucleus (Homo sapiens)


NOTCH2 intracellular domain regulates transcription (Homo sapiens)


Phosphorylation of the APC/C (Homo sapiens)


PKMTs methylate histone lysines (Homo sapiens)


Pre-NOTCH Processing in the Endoplasmic Reticulum (Homo sapiens)


ROS and RNS production in phagocytes (Homo sapiens)


rRNA modification in the mitochondrion (Homo sapiens)


SMAC, XIAP-regulated apoptotic response (Homo sapiens)


Sulfide oxidation to sulfate (Homo sapiens)


Voltage gated Potassium channels (Homo sapiens)


positive regulation of endothelial cell proliferation


positive regulation of mesenchymal cell proliferation


regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis


DNA methylation-dependent constitutive heterochromatin formation


cell surface receptor protein serine/threonine kinase signaling pathway


negative regulation of catabolic process


regulation of ketone biosynthetic process


regulation of peptidyl-threonine phosphorylation


negative regulation of cell cycle process


positive regulation of muscle adaptation


smoothened signaling pathway involved in ventral spinal cord patterning


negative regulation of Wnt signaling pathway


regulation of granulocyte differentiation


regulation of glucocorticoid metabolic process


regulation of glucocorticoid biosynthetic process


positive regulation of deoxyribonuclease activity


negative regulation of hormone metabolic process


protein modification by small protein conjugation


transforming growth factor beta2 production


regulation of nuclear cell cycle DNA replication


positive regulation of transmembrane transport


somatic stem cell population maintenance


regulation of Rac protein signal transduction


negative regulation of Rho protein signal transduction


positive regulation of dephosphorylation


peroxisome proliferator activated receptor signaling pathway


negative regulation of chromatin binding


cellular response to vascular endothelial growth factor stimulus


vascular endothelial growth factor signaling pathway


epigenetic regulation of gene expression


regulation of development, heterochronic


negative regulation of protein catabolic process


steroid hormone receptor signaling pathway


regulation of insulin-like growth factor receptor signaling pathway


development of primary sexual characteristics


negative regulation of myeloid cell differentiation


positive regulation of osteoblast differentiation


positive regulation of protein catabolic process


negative regulation of gene expression, epigenetic


positive regulation of mitotic cell cycle


positive regulation of translational initiation


negative regulation of vitamin metabolic process


negative regulation of neurotransmitter secretion


positive regulation of mRNA splicing, via spliceosome


positive regulation of fibroblast proliferation


negative regulation of response to stimulus


positive regulation of hair follicle maturation


positive regulation of transferase activity


negative regulation of neurotransmitter transport


positive regulation of focal adhesion assembly


regulation of branching involved in prostate gland morphogenesis


regulation of regulatory ncRNA processing


cellular response to carbohydrate stimulus


cellular response to prostaglandin stimulus


cell proliferation involved in kidney development


cell proliferation involved in metanephros development


positive regulation of release of cytochrome c from mitochondria


regulation of cellular response to growth factor stimulus


neuronal stem cell population maintenance


calcitonin family receptor signaling pathway


regulation of postsynaptic cytosolic calcium ion concentration


regulation of cellular response to insulin stimulus


negative regulation of cellular response to insulin stimulus


positive regulation of execution phase of apoptosis


regulation of extracellular matrix assembly