Alzheimer disease

biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing


adiponectin measurement

biolink:PhenotypicFeature biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing


Subcutaneous Fat, Abdominal

biolink:AnatomicalEntity biolink:PhysicalEssence biolink:OrganismalEntity biolink:SubjectOfInvestigation biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent


Basophil percentage measurement

biolink:Procedure biolink:ActivityAndBehavior biolink:NamedThing biolink:Occurrent biolink:PhysicalEssenceOrOccurrent


Eosinophil percent differential count (procedure)


omega-3 polyunsaturated fatty acid measurement


omega-6 polyunsaturated fatty acid measurement


BMI-adjusted fasting blood glucose measurement


BMI-adjusted fasting blood insulin measurement


serum gamma-glutamyl transferase measurement


intermediate density lipoprotein measurement


low density lipoprotein cholesterol measurement


left ventricular ejection fraction measurement


Left ventricular mass to end-diastolic volume ratio


mean corpuscular hemoglobin concentration


Microalbuminuria due to type 2 diabetes mellitus


Monocyte percent differential count (procedure)


metabolic dysfunction-associated steatotic liver disease


Non-high density lipoprotein cholesterol (substance)


Nucleated red blood cell count procedure


Pulse Rate

biolink:ClinicalAttribute biolink:Attribute biolink:OntologyClass biolink:NamedThing


Right ventricular ejection fraction (observable entity)


Right ventricular stroke volume

biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent


acquired aneurysmal subarachnoid hemorrhage


left ventricular stroke volume measurement


deadenylation-dependent decapping of nuclear-transcribed mRNA


maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)


maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)


release of cytochrome c from mitochondria


negative regulation of T cell mediated cytotoxicity


response to molecule of bacterial origin


production of molecular mediator involved in inflammatory response


cytokine production involved in inflammatory response


positive regulation of peptide secretion


negative regulation of adaptive immune response


dolichyl diphosphate biosynthetic process


endoplasmic reticulum to Golgi vesicle-mediated transport


retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum


negative regulation of epidermal growth factor-activated receptor activity


regulation of epidermal growth factor-activated receptor activity


biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent

G protein-coupled receptor signaling pathway


G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger


adenylate cyclase-inhibiting dopamine receptor signaling pathway


nitric oxide mediated signal transduction


small GTPase-mediated signal transduction


regulation of G protein-coupled receptor signaling pathway


negative regulation of cell population proliferation


fibroblast growth factor receptor signaling pathway


intrinsic apoptotic signaling pathway in response to DNA damage


positive regulation of catabolic process


negative regulation of platelet activation


negative regulation of lamellipodium assembly


positive regulation of endothelial cell migration


positive regulation of epithelial cell migration


positive regulation of organelle organization


positive regulation of muscle cell apoptotic process


positive regulation of striated muscle cell apoptotic process


regulation of alkaline phosphatase activity


regulation of macrophage derived foam cell differentiation


positive regulation of macrophage derived foam cell differentiation


regulation of nitric oxide mediated signal transduction


positive regulation of cGMP-mediated signaling


negative regulation of cGMP-mediated signaling


positive regulation of peptidyl-threonine phosphorylation


regulation of tumor necrosis factor-mediated signaling pathway


regulation of keratinocyte proliferation


negative regulation of keratinocyte proliferation


positive regulation of triglyceride biosynthetic process


regulation of triglyceride catabolic process


positive regulation of triglyceride catabolic process


positive regulation of smooth muscle cell migration


regulation of fatty acid metabolic process


short-chain fatty acid catabolic process


substrate-independent telencephalic tangential migration


cerebral cortex GABAergic interneuron differentiation


cerebral cortex GABAergic interneuron development


positive regulation of cell-cell adhesion


signal transduction involved in regulation of gene expression


locomotion involved in locomotory behavior


positive regulation of fatty acid beta-oxidation


positive regulation of insulin secretion


positive regulation of response to external stimulus


telomere maintenance via semi-conservative replication


endoplasmic reticulum calcium ion homeostasis


negative regulation of endoplasmic reticulum calcium ion concentration


positive regulation of interleukin-8 production


regulation of superoxide anion generation


negative regulation of myeloid cell apoptotic process


tumor necrosis factor-mediated signaling pathway


mammary gland epithelial cell proliferation


negative regulation of catecholamine secretion


regulation of cell adhesion mediated by integrin


positive regulation of cell adhesion mediated by integrin


positive regulation of cell-cell adhesion mediated by integrin


positive regulation of NAD(P)H oxidase activity


regulation of maintenance of sister chromatid cohesion


very-low-density lipoprotein particle assembly


high-density lipoprotein particle assembly


high-density lipoprotein particle clearance


G protein-coupled purinergic receptor signaling pathway


insulin secretion involved in cellular response to glucose stimulus


positive regulation of insulin secretion involved in cellular response to glucose stimulus


platelet-derived growth factor receptor-alpha signaling pathway


positive regulation of renal sodium excretion


positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway


signal transduction in absence of ligand


positive regulation of activated T cell proliferation


regulation of cell population proliferation


regulation of fatty acid biosynthetic process


fat-soluble vitamin biosynthetic process


negative regulation of amyloid precursor protein biosynthetic process


negative regulation of catalytic activity


negative regulation of vascular permeability


negative regulation of canonical NF-kappaB signal transduction


positive regulation of protein-containing complex disassembly


positive regulation of blood vessel endothelial cell migration


polyadenylation-dependent RNA catabolic process


negative regulation of molecular function


negative regulation of lymphocyte differentiation


positive regulation of macrophage differentiation


negative regulation of osteoblast differentiation


positive regulation of fatty acid biosynthetic process


positive regulation of lipid metabolic process


positive regulation of mitotic nuclear division


negative regulation of sister chromatid cohesion


positive regulation of sister chromatid cohesion


positive regulation of fatty acid metabolic process


positive regulation of centriole replication


positive regulation of hormone secretion


positive regulation of lipid biosynthetic process


vascular endothelial growth factor receptor signaling pathway


regulation of neuronal synaptic plasticity


negative regulation of smooth muscle cell proliferation


positive regulation of inflammatory response


negative regulation of peptidyl-tyrosine phosphorylation


defense response to Gram-negative bacterium


positive regulation of lipid catabolic process


regulation of nitric-oxide synthase activity


positive regulation of nitric-oxide synthase activity


negative regulation of DNA metabolic process


positive regulation of DNA metabolic process


positive regulation of cyclic-nucleotide phosphodiesterase activity


negative regulation of transferase activity


positive regulation of oxidoreductase activity


positive regulation of mitochondrial calcium ion concentration


positive regulation of neurotransmitter uptake


positive regulation of neurotransmitter transport


negative regulation of cardiac muscle contraction


convergent extension involved in gastrulation


convergent extension involved in axis elongation


convergent extension involved in organogenesis


regulation of postsynaptic membrane potential


regulation of phospholipid catabolic process


positive regulation of response to cytokine stimulus


negative regulation of protein tyrosine kinase activity


retina vasculature development in camera-type eye


positive regulation of triglyceride lipase activity


positive regulation of small molecule metabolic process


regulation of lymphocyte apoptotic process


positive regulation of lymphocyte apoptotic process


positive regulation of T cell apoptotic process


protein localization to endoplasmic reticulum


protein localization to chromosome, centromeric region


protein localization to extracellular region


endoplasmic reticulum tubular network organization


determination of liver left/right asymmetry


protein deubiquitination involved in ubiquitin-dependent protein catabolic process


purine-containing compound transmembrane transport


reactive oxygen species metabolic process


IRES-dependent viral translational initiation


positive regulation of cell cycle process


regulation of release of cytochrome c from mitochondria


negative regulation of release of cytochrome c from mitochondria


regulation of triglyceride metabolic process


positive regulation of calcium ion import


negative regulation of excitatory postsynaptic potential


regulation of plasma lipoprotein particle levels


cell surface receptor signaling pathway via STAT


monoatomic anion transmembrane transport


chemical synaptic transmission, postsynaptic


positive regulation of neuroinflammatory response


negative regulation of cytokine production involved in inflammatory response


positive regulation of long-term synaptic potentiation


positive regulation of autophagosome maturation


negative regulation of signal transduction in absence of ligand


cellular response to oxygen-containing compound


positive regulation of protein depolymerization


regulation of ATPase-coupled calcium transmembrane transporter activity


negative regulation of cell cycle checkpoint


regulation of intrinsic apoptotic signaling pathway in response to DNA damage


positive regulation of protein localization to synapse


positive regulation of neutrophil activation


negative regulation of lamellipodium organization


negative regulation of calcium ion transmembrane transport


positive regulation of tumor necrosis factor-mediated signaling pathway


regulation of synaptic vesicle recycling


positive regulation of tumor necrosis factor superfamily cytokine production


positive regulation of DNA catabolic process


positive regulation of cellular response to transforming growth factor beta stimulus


positive regulation of anion transmembrane transport


negative regulation of telomere maintenance via telomere lengthening


negative regulation of vascular associated smooth muscle cell proliferation


vascular associated smooth muscle cell migration


positive regulation of vascular associated smooth muscle cell migration


positive regulation of protein localization to centrosome


positive regulation of receptor signaling pathway via STAT


positive regulation of leukocyte adhesion to vascular endothelial cell


regulation of morphogenesis of an epithelium


negative regulation of morphogenesis of an epithelium


negative regulation of DNA damage checkpoint


regulation of leukocyte apoptotic process


positive regulation of leukocyte apoptotic process


negative regulation of signaling receptor activity


negative regulation of DNA biosynthetic process


regulation of T-helper 17 type immune response


positive regulation of chemokine (C-X-C motif) ligand 2 production


negative regulation of cellular senescence


regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell


negative regulation of osteoclast development


regulation of apoptotic signaling pathway


negative regulation of apoptotic signaling pathway


regulation of extrinsic apoptotic signaling pathway


regulation of extrinsic apoptotic signaling pathway in absence of ligand


regulation of phosphatidylcholine biosynthetic process


carbohydrate import across plasma membrane


central nervous system myelin maintenance


granzyme-mediated programmed cell death signaling pathway


interneuron migration from the subpallium to the cortex


L-glutamate import across plasma membrane


mitochondrion-endoplasmic reticulum membrane tethering


negative regulation of ATPase-coupled calcium transmembrane transporter activity


negative regulation of filopodium assembly


negative regulation of granulocyte chemotaxis


negative regulation of interleukin-18 production


negative regulation of ion transmembrane transporter activity


negative regulation of lipoprotein metabolic process


negative regulation of receptor recycling


negative regulation of secondary metabolite biosynthetic process


positive regulation of axon extension involved in axon guidance


positive regulation of exosomal secretion


positive regulation of mast cell chemotaxis


positive regulation of mesenchymal stem cell proliferation


positive regulation of protein secretion


positive regulation of triglyceride metabolic process


regulation of insulin secretion involved in cellular response to glucose stimulus


regulation of myeloid cell apoptotic process


regulation of phosphatidylcholine metabolic process


T cell proliferation involved in immune response


T follicular helper cell differentiation


urinary bladder smooth muscle contraction


vascular associated smooth muscle cell proliferation


90S preribosome

biolink:CellularComponent biolink:AnatomicalEntity biolink:PhysicalEssence biolink:OrganismalEntity biolink:SubjectOfInvestigation biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent


carboxy-terminal domain protein kinase complex


cyclin-dependent protein kinase holoenzyme complex


equatorial microtubule organizing center


nuclear cyclin-dependent protein kinase holoenzyme complex


triglyceride-rich plasma lipoprotein particle


acid-thiol ligase activity

biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:ThingWithTaxon biolink:NamedThing biolink:PhysicalEssenceOrOccurrent


monoatomic anion transmembrane transporter activity


ATPase-coupled inorganic anion transmembrane transporter activity


carbohydrate:monoatomic cation symporter activity


carbohydrate derivative transmembrane transporter activity


carbohydrate transmembrane transporter activity


chloride transmembrane transporter activity


cyclin-dependent protein kinase activity


cysteine-type endopeptidase inhibitor activity


D-glucose transmembrane transporter activity


efflux transmembrane transporter activity


fibroblast growth factor receptor binding


G-protein beta/gamma-subunit complex binding


heparan sulfate sulfotransferase activity


histone H4K20 methyltransferase activity


hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds


hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides


inorganic anion transmembrane transporter activity


K63-linked polyubiquitin modification-dependent protein binding


lipopolysaccharide immune receptor activity


nucleobase-containing compound transmembrane transporter activity


nucleotide transmembrane transporter activity


organophosphate ester transmembrane transporter activity


oxidative phosphorylation uncoupler activity


oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor


peroxisome proliferator activated receptor binding


phosphatidylcholine-sterol O-acyltransferase activator activity


purine nucleotide transmembrane transporter activity


RNA polymerase II CTD heptapeptide repeat kinase activity


sugar transmembrane transporter activity


toxin transmembrane transporter activity


transferase activity, transferring sulphur-containing groups


UDP-N-acetylglucosamine transmembrane transporter activity


uridine transmembrane transporter activity


vascular endothelial growth factor receptor activity


vascular endothelial growth factor binding


Acetylcholine inhibits contraction of outer hair cells (Homo sapiens)


Activation of BAD and translocation to mitochondria  (Homo sapiens)


Adenylate cyclase inhibitory pathway (Homo sapiens)


Alpha-oxidation of phytanate (Homo sapiens)


negative regulation of killing of cells of another organism


Citric acid cycle (TCA cycle) (Homo sapiens)


Defective factor VIII causes hemophilia A (Homo sapiens)


Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) (Homo sapiens)


Diseases of Mismatch Repair (MMR) (Homo sapiens)


FGFR2b ligand binding and activation (Homo sapiens)


G alpha (s) signalling events (Homo sapiens)


G alpha (z) signalling events (Homo sapiens)


HDR through MMEJ (alt-NHEJ) (Homo sapiens)


Ion transport by P-type ATPases (Homo sapiens)


Metabolism of steroid hormones (Homo sapiens)


mitochondrial fatty acid beta-oxidation of saturated fatty acids (Homo sapiens)


Negative feedback regulation of MAPK pathway (Homo sapiens)


Negative regulation of TCF-dependent signaling by WNT ligand antagonists (Homo sapiens)


Negative regulation of the PI3K/AKT network (Homo sapiens)


Ovarian tumor domain proteases (Homo sapiens)


adhesion of symbiont infection structure to host


POLB-Dependent Long Patch Base Excision Repair (Homo sapiens)


Regulation of localization of FOXO transcription factors (Homo sapiens)


regulation of regulatory T cell differentiation


RUNX2 regulates genes involved in cell migration (Homo sapiens)


Scavenging by Class B Receptors (Homo sapiens)


Sema4D in semaphorin signaling (Homo sapiens)


Sema4D induced cell migration and growth-cone collapse (Homo sapiens)


Signal regulatory protein family interactions (Homo sapiens)


SLC-mediated transmembrane transport (Homo sapiens)


SLC transporter disorders (Homo sapiens)


Synthesis of 5-eicosatetraenoic acids (Homo sapiens)


Synthesis of substrates in N-glycan biosythesis (Homo sapiens)


Terminal pathway of complement (Homo sapiens)


Aerobic respiration and respiratory electron transport (Homo sapiens)


death-inducing signaling complex assembly


positive regulation of ceramide biosynthetic process


TP53 Regulates Metabolic Genes (Homo sapiens)


TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling (Homo sapiens)


Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA (Homo sapiens)


VEGF ligand-receptor interactions (Homo sapiens)


Zinc efflux and compartmentalization by the SLC30 family (Homo sapiens)


blood vessel endothelial cell proliferation involved in sprouting angiogenesis


optic cup morphogenesis involved in camera-type eye development


Wnt signaling pathway involved in heart development


regulation of Wnt signaling pathway involved in heart development


mesenchymal to epithelial transition involved in metanephros morphogenesis


chondrocyte development involved in endochondral bone morphogenesis


enzyme-linked receptor protein signaling pathway


receptor guanylyl cyclase signaling pathway


cell surface receptor protein tyrosine kinase signaling pathway


adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway


negative regulation of adenylate cyclase activity


adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway


G protein-coupled glutamate receptor signaling pathway


purine nucleoside triphosphate catabolic process


deoxyribonucleoside triphosphate catabolic process


positive regulation of alkaline phosphatase activity


positive regulation of cell morphogenesis


peptidyl-proline hydroxylation to 4-hydroxy-L-proline


nonribosomal peptide biosynthetic process


spinal cord motor neuron cell fate specification


olfactory bulb interneuron differentiation


heparan sulfate proteoglycan metabolic process


negative regulation of bone mineralization


negative regulation of BMP signaling pathway


positive regulation of actin filament depolymerization


negative regulation of microtubule polymerization


SCF-dependent proteasomal ubiquitin-dependent protein catabolic process


post-translational protein targeting to membrane, translocation


regulation of protein autophosphorylation


regulation of T cell differentiation in thymus


negative regulation of T cell differentiation in thymus


negative regulation of intracellular estrogen receptor signaling pathway


positive regulation of tissue remodeling


glial cell-derived neurotrophic factor receptor signaling pathway


G protein-coupled opioid receptor signaling pathway


regulation of catecholamine metabolic process


long-chain fatty acid biosynthetic process


ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway


regulation of protein-containing complex disassembly


negative regulation of leukocyte degranulation


negative regulation of mast cell degranulation


negative regulation by host of viral transcription


positive regulation of cAMP-mediated signaling


negative regulation of protein kinase activity by regulation of protein phosphorylation


positive regulation of viral genome replication


regulation of megakaryocyte differentiation


positive regulation of megakaryocyte differentiation


negative regulation of Notch signaling pathway


anatomical structure formation involved in morphogenesis


3'-phosphoadenosine 5'-phosphosulfate metabolic process


positive regulation of dendrite morphogenesis


positive regulation of helicase activity


positive regulation of NK T cell activation


positive regulation of synaptic transmission, glutamatergic


positive regulation of transmission of nerve impulse


positive regulation of epithelial cell proliferation involved in wound healing


regulation of dopamine receptor signaling pathway


regulation of nuclear-transcribed mRNA poly(A) tail shortening


positive regulation of response to type II interferon


negative regulation of gastric acid secretion


mammary gland epithelial cell differentiation


branching involved in labyrinthine layer morphogenesis


positive regulation of dendritic spine morphogenesis


positive regulation of tooth mineralization


negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway


maintenance of protein location in mitochondrion


positive regulation of monocyte chemotaxis


programmed cell death in response to reactive oxygen species


retrograde trans-synaptic signaling by lipid


neurotransmitter receptor transport, postsynaptic endosome to lysosome


regulation of neurotransmitter receptor activity


regulation of long-chain fatty acid import into cell


positive regulation of long-term synaptic depression


positive regulation of response to reactive oxygen species


negative regulation of ERBB signaling pathway


positive regulation of hydrogen peroxide-mediated programmed cell death


negative regulation of cell junction assembly


positive regulation of hematopoietic stem cell proliferation


negative regulation of peptidyl-cysteine S-nitrosylation


positive regulation of response to oxidative stress


regulation of PERK-mediated unfolded protein response


regulation of connective tissue replacement


negative regulation of synapse organization


regulation of peptidyl-cysteine S-nitrosylation


negative regulation of dendrite development


negative regulation of neural precursor cell proliferation


negative regulation of fatty acid transport


regulation of lamellipodium morphogenesis


positive regulation of lamellipodium morphogenesis


positive regulation of early endosome to late endosome transport


positive regulation of cytoplasmic translation


adenylate cyclase-modulating G protein-coupled receptor signaling pathway


aminoglycoside antibiotic metabolic process


AV node cell to bundle of His cell signaling


deoxyribonucleoside triphosphate metabolic process


double-strand break repair via classical nonhomologous end joining


growth plate cartilage chondrocyte development


heparan sulfate proteoglycan biosynthetic process


leukemia inhibitory factor signaling pathway


negative regulation of autophagosome maturation


negative regulation of centrosome duplication


negative regulation of Wnt signaling pathway involved in heart development


positive regulation of connective tissue replacement


positive regulation of prostaglandin biosynthetic process


purine deoxyribonucleoside triphosphate metabolic process


purine deoxyribonucleotide biosynthetic process


regulation of hydrogen peroxide-mediated programmed cell death


regulation of iron ion transmembrane transport


regulation of long-chain fatty acid import across plasma membrane


regulation of natural killer cell mediated immune response to tumor cell


regulation of voltage-gated sodium channel activity


spinal cord oligodendrocyte cell differentiation


endoplasmic reticulum protein-containing complex


extrinsic component of postsynaptic specialization membrane


guanyl-nucleotide exchange factor complex


mitochondria-associated endoplasmic reticulum membrane contact site


phosphatidylinositol 3-kinase complex, class III


aspartic-type endopeptidase inhibitor activity


ATPase-coupled intramembrane lipid transporter activity


ciliary neurotrophic factor receptor activity


ciliary neurotrophic factor receptor binding


RNA endonuclease activity producing 5'-phosphomonoesters, hydrolytic mechanism


G protein-coupled glutamate receptor activity


G protein-coupled opioid receptor activity


[heparan sulfate]-glucosamine 3-sulfotransferase activity


histone arginine N-methyltransferase activity


hypoglycin A gamma-glutamyl transpeptidase activity


solute:inorganic anion antiporter activity


intraciliary transport particle B binding


intramembrane lipid transporter activity


K48-linked polyubiquitin modification-dependent protein binding


magnesium ion transmembrane transporter activity


neurotransmitter transmembrane transporter activity


oxidoreductase activity, acting on CH or CH2 groups


oxidoreductase activity, acting on NAD(P)H


phosphatidylinositol 3-kinase regulator activity


phosphatidylinositol 3-kinase regulatory subunit binding


Activated NTRK2 signals through RAS (Homo sapiens)


Activated NTRK3 signals through RAS (Homo sapiens)


Activation of the pre-replicative complex (Homo sapiens)


AKT phosphorylates targets in the nucleus (Homo sapiens)


Association of TriC/CCT with target proteins during biosynthesis (Homo sapiens)


Biosynthesis of EPA-derived SPMs (Homo sapiens)


Biosynthesis of maresin-like SPMs (Homo sapiens)


CD28 dependent PI3K/Akt signaling (Homo sapiens)


Competing endogenous RNAs (ceRNAs) regulate PTEN translation (Homo sapiens)


Constitutive Signaling by Aberrant PI3K in Cancer (Homo sapiens)


Constitutive Signaling by Overexpressed ERBB2 (Homo sapiens)


Creation of C4 and C2 activators (Homo sapiens)


Cytosolic iron-sulfur cluster assembly (Homo sapiens)


Diseases associated with glycosaminoglycan metabolism (Homo sapiens)


Diseases of glycosylation (Homo sapiens)


DNA strand elongation involved in DNA replication


Downstream signaling of activated FGFR3 (Homo sapiens)


EGFR Transactivation by Gastrin (Homo sapiens)


FCERI mediated Ca+2 mobilization (Homo sapiens)


FLT3 signaling through SRC family kinases (Homo sapiens)


D-glucuronate catabolic process to D-xylulose 5-phosphate


Free fatty acid receptors (Homo sapiens)


FRS-mediated FGFR3 signaling (Homo sapiens)


nucleotide-excision repair, DNA gap filling


Glycogen breakdown (glycogenolysis) (Homo sapiens)


Highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Homo sapiens)


Insulin receptor signalling cascade (Homo sapiens)


Intracellular signaling by second messengers (Homo sapiens)


LTC4-CYSLTR mediated IL4 production (Homo sapiens)


MAP3K8 (TPL2)-dependent MAPK1/3 activation (Homo sapiens)


MECP2 regulates transcription factors (Homo sapiens)


MET activates RAS signaling (Homo sapiens)


Metabolism of carbohydrates and carbohydrate derivatives (Homo sapiens)


Miscellaneous transport and binding events (Homo sapiens)


Molecules associated with elastic fibres (Homo sapiens)


Negative regulation of FGFR3 signaling (Homo sapiens)


Negative regulation of FLT3 (Homo sapiens)


PCNA-Dependent Long Patch Base Excision Repair (Homo sapiens)


PI3K/AKT Signaling in Cancer (Homo sapiens)


Processive synthesis on the lagging strand (Homo sapiens)


positive regulation of error-prone translesion synthesis


Regulation of commissural axon pathfinding by SLIT and ROBO (Homo sapiens)


Regulation of gene expression in beta cells (Homo sapiens)


Regulation of gene expression in early pancreatic precursor cells (Homo sapiens)


Regulation of PTEN mRNA translation (Homo sapiens)


Regulation of TP53 Activity through Acetylation (Homo sapiens)


Resolution of AP sites via the multiple-nucleotide patch replacement pathway (Homo sapiens)


ROBO receptors bind AKAP5 (Homo sapiens)


SHC-mediated cascade:FGFR1 (Homo sapiens)


SHC-mediated cascade:FGFR3 (Homo sapiens)


SHC-mediated cascade:FGFR4 (Homo sapiens)


SHC1 events in ERBB4 signaling (Homo sapiens)


Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants (Homo sapiens)


Synthesis of UDP-N-acetyl-glucosamine (Homo sapiens)


The retinoid cycle in cones (daylight vision) (Homo sapiens)


Transcriptional Regulation by VENTX (Homo sapiens)


Translation of Replicase and Assembly of the Replication Transcription Complex (Homo sapiens)


nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay


RNA splicing, via transesterification reactions


negative regulation of cytokine production


regulation of the force of heart contraction


pattern recognition receptor signaling pathway


cell activation involved in immune response


macrophage activation involved in immune response


B cell activation involved in immune response


immunoglobulin production involved in immunoglobulin-mediated immune response


production of molecular mediator of immune response


humoral immune response mediated by circulating immunoglobulin


adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains


antigen processing and presentation of endogenous peptide antigen


antigen processing and presentation of peptide or polysaccharide antigen via MHC class II


regulation of antigen processing and presentation


negative regulation of antigen processing and presentation


positive regulation of antigen processing and presentation


regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II


regulation of antigen processing and presentation of peptide antigen


positive regulation of tolerance induction


positive regulation of T cell tolerance induction


positive regulation of immune system process


positive regulation of leukocyte migration


negative regulation of immune effector process


positive regulation of immune effector process


regulation of production of molecular mediator of immune response


negative regulation of production of molecular mediator of immune response


regulation of leukocyte mediated immunity


negative regulation of leukocyte mediated immunity


positive regulation of leukocyte mediated immunity


regulation of lymphocyte mediated immunity


negative regulation of lymphocyte mediated immunity


negative regulation of B cell mediated immunity


positive regulation of B cell mediated immunity


positive regulation of myeloid leukocyte differentiation


immune response-regulating signaling pathway


immune response-inhibiting signal transduction


immune response-inhibiting cell surface receptor signaling pathway


immune response-regulating cell surface receptor signaling pathway


negative regulation of humoral immune response


positive regulation of humoral immune response


regulation of humoral immune response mediated by circulating immunoglobulin


negative regulation of humoral immune response mediated by circulating immunoglobulin


positive regulation of humoral immune response mediated by circulating immunoglobulin


regulation of the force of heart contraction by chemical signal


muscle hypertrophy in response to stress


adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway


G protein-coupled acetylcholine receptor signaling pathway


attachment of spindle microtubules to kinetochore


extrinsic apoptotic signaling pathway via death domain receptors


negative regulation of phosphorus metabolic process


positive regulation of nitric oxide mediated signal transduction


negative regulation of sodium ion transport


regulation of mitochondrion organization


negative regulation of D-glucose transmembrane transport


telomere maintenance via telomere lengthening


positive regulation of cholesterol efflux


positive regulation of cholesterol storage


negative regulation of cholesterol storage


negative regulation of triglyceride storage


regulation of very-low-density lipoprotein particle clearance


positive regulation of peptidase activity


negative regulation of neuron projection development


regulation of high-density lipoprotein particle clearance


fatty acid elongation, saturated fatty acid


antigen processing and presentation of endogenous antigen


positive regulation of granulocyte differentiation


stress-activated protein kinase signaling cascade


positive regulation of protein-containing complex assembly


negative regulation of cell projection organization


regulation of lipopolysaccharide-mediated signaling pathway


negative regulation of lipopolysaccharide-mediated signaling pathway


positive regulation of telomere maintenance


regulation of actin filament bundle assembly


positive regulation of actin filament bundle assembly


activation of store-operated calcium channel activity


regulation of Cdc42 protein signal transduction


detection of molecule of bacterial origin


negative regulation of interleukin-12 production


negative regulation of interleukin-2 production


positive regulation of interleukin-10 production


positive regulation of CREB transcription factor activity


negative regulation of natural killer cell activation


glomerular basement membrane development


negative regulation of transforming growth factor beta1 production


regulation of actin filament-based process


mitochondrial respiratory chain complex assembly


regulation of peptidyl-serine phosphorylation


negative regulation of peptidyl-serine phosphorylation


regulation of intracellular protein transport


fatty acid beta-oxidation using acyl-CoA dehydrogenase


maintenance of sister chromatid cohesion


regulation of toll-like receptor signaling pathway


negative regulation of toll-like receptor 2 signaling pathway


negative regulation of toll-like receptor 4 signaling pathway


Arp2/3 complex-mediated actin nucleation


regulation of Arp2/3 complex-mediated actin nucleation


negative regulation of Arp2/3 complex-mediated actin nucleation


regulation of glial cell apoptotic process


triglyceride-rich lipoprotein particle remodeling


high-density lipoprotein particle remodeling


very-low-density lipoprotein particle clearance


response to macrophage colony-stimulating factor


apolipoprotein A-I-mediated signaling pathway


collagen-activated tyrosine kinase receptor signaling pathway


positive regulation of cell migration by vascular endothelial growth factor signaling pathway


macrophage colony-stimulating factor signaling pathway


amyloid precursor protein metabolic process


amyloid precursor protein catabolic process


regulation of protein-containing complex assembly


negative regulation of monoatomic ion transport


positive regulation of DNA damage response, signal transduction by p53 class mediator


positive regulation of cellular component biogenesis


positive regulation of regulatory T cell differentiation


regulation of inner ear auditory receptor cell differentiation


negative regulation of monocyte differentiation


positive regulation of monocyte differentiation


negative regulation of epidermis development


negative regulation of glial cell differentiation


negative regulation of fatty acid biosynthetic process


positive regulation of isotype switching


negative regulation of lipid metabolic process


negative regulation of complement activation


positive regulation of complement activation


positive regulation of gamma-delta T cell activation


regulation of mRNA splicing, via spliceosome


regulation of receptor-mediated endocytosis


positive regulation of receptor-mediated endocytosis


negative regulation of receptor-mediated endocytosis


positive regulation of isotype switching to IgA isotypes


positive regulation of isotype switching to IgG isotypes


collateral sprouting in absence of injury


negative regulation of astrocyte differentiation


regulation of calcium-mediated signaling


antigen receptor-mediated signaling pathway


regulation of B cell receptor signaling pathway


negative regulation of B cell receptor signaling pathway


positive regulation of B cell receptor signaling pathway


negative regulation of lipid catabolic process


negative regulation of lipid biosynthetic process


negative regulation of cellular component organization


positive regulation of cellular component organization


negative regulation of protein metabolic process


positive regulation of hydrolase activity


negative regulation of cytoskeleton organization


positive regulation of cytoskeleton organization


positive regulation of stress fiber assembly


negative regulation of calcium ion transport


negative regulation of nervous system development


regulation of resting membrane potential


apoptotic process involved in morphogenesis


regulation of vesicle-mediated transport


regulation of ER to Golgi vesicle-mediated transport


positive regulation of macrophage cytokine production


regulation of chemokine-mediated signaling pathway


regulation of establishment of protein localization


positive regulation of ERK1 and ERK2 cascade


thrombin-activated receptor signaling pathway


positive regulation of neuron projection regeneration


regulation of protein exit from endoplasmic reticulum


positive regulation of protein exit from endoplasmic reticulum


cellular response to lipoprotein particle stimulus


cellular response to low-density lipoprotein particle stimulus


macrophage inflammatory protein-1 alpha production


negative regulation of transforming growth factor beta production


tumor necrosis factor superfamily cytokine production


triglyceride-rich lipoprotein particle clearance


positive regulation of lipid kinase activity


negative regulation of calcium ion import


regulation of protein targeting to membrane


positive regulation of protein targeting to membrane


regulation of superoxide metabolic process


regulation of membrane lipid distribution


type B pancreatic cell apoptotic process


response to mitochondrial depolarisation


regulation of actin filament organization


cellular response to oxidised low-density lipoprotein particle stimulus


positive regulation of lymphocyte chemotaxis


negative regulation of neuroinflammatory response


amyloid-beta clearance by cellular catabolic process


regulation of endoplasmic reticulum unfolded protein response


negative regulation of endoplasmic reticulum unfolded protein response


regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay


positive regulation of amyloid-beta clearance


negative regulation of NLRP3 inflammasome complex assembly


regulation of long-term synaptic potentiation


regulation of defense response to bacterium


positive regulation of defense response to bacterium


positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway


positive regulation of non-canonical NF-kappaB signal transduction


positive regulation of store-operated calcium channel activity


negative regulation of extrinsic apoptotic signaling pathway via death domain receptors


positive regulation of extrinsic apoptotic signaling pathway via death domain receptors


neuron projection extension involved in neuron projection guidance


positive regulation of apoptotic process involved in morphogenesis


regulation of protein localization to synapse


regulation of intracellular signal transduction


positive regulation of intracellular signal transduction


negative regulation of neutrophil activation


regulation of supramolecular fiber organization


negative regulation of supramolecular fiber organization


positive regulation of supramolecular fiber organization


regulation of tau-protein kinase activity


regulation of amyloid precursor protein catabolic process


negative regulation of amyloid precursor protein catabolic process


positive regulation of response to wounding


regulation of protein localization to plasma membrane


regulation of regulated secretory pathway


reactive oxygen species biosynthetic process


positive regulation of reactive oxygen species biosynthetic process


protein localization to ciliary membrane


negative regulation of blood circulation


negative regulation of tumor necrosis factor superfamily cytokine production


positive regulation of I-kappaB phosphorylation


positive regulation of voltage-gated potassium channel activity


positive regulation of protein localization


negative regulation of cellular response to transforming growth factor beta stimulus


negative regulation of PERK-mediated unfolded protein response


regulation of cellular response to macrophage colony-stimulating factor stimulus


regulation of microglial cell activation


regulation of adipose tissue development


regulation of telomere maintenance via telomere lengthening


positive regulation of telomere maintenance via telomere lengthening


regulation of protein localization to cell periphery


negative regulation of protein localization to cell periphery


protein localization to ciliary transition zone


regulation of metalloendopeptidase activity


regulation of chaperone-mediated autophagy


positive regulation of apoptotic process involved in development


regulation of receptor signaling pathway via STAT


positive regulation of establishment of protein localization


negative regulation of metallopeptidase activity


positive regulation of aspartic-type peptidase activity


regulation of protein localization to membrane


negative regulation of protein localization to membrane


calcium ion export across plasma membrane


potassium ion import across plasma membrane


negative regulation of protein localization to cell surface


regulation of reactive oxygen species metabolic process


positive regulation of reactive oxygen species metabolic process


positive regulation of lymphocyte migration


positive regulation of apoptotic cell clearance


positive regulation of DNA biosynthetic process


positive regulation of sodium ion transmembrane transporter activity


negative regulation of dendritic cell apoptotic process


negative regulation of type B pancreatic cell apoptotic process


regulation of bicellular tight junction assembly


regulation of integrin-mediated signaling pathway


positive regulation of endocytic recycling


positive regulation of extrinsic apoptotic signaling pathway


positive regulation of chromosome organization


chemokine (C-X-C motif) ligand 12 signaling pathway


chromosome localization to nuclear envelope involved in homologous chromosome segregation


diadenosine polyphosphate catabolic process


diadenosine polyphosphate metabolic process


Fc receptor mediated inhibitory signaling pathway


lipid transport across blood-brain barrier


mast cell activation involved in immune response


myeloid cell activation involved in immune response


negative regulation of amyloid fibril formation


negative regulation of astrocyte activation


negative regulation of axon extension involved in axon guidance


negative regulation of cellular response to oxidative stress


negative regulation of glial cell apoptotic process


negative regulation of glycoprotein metabolic process


negative regulation of lens fiber cell differentiation


negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay


negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay


negative regulation of triglyceride catabolic process


negative regulation of triglyceride metabolic process


peptide antigen assembly with MHC class II protein complex


peptide antigen assembly with MHC protein complex


positive regulation of chemokine (C-X-C motif) ligand 1 production


positive regulation of chromosome condensation


positive regulation of inclusion body assembly


positive regulation of mRNA metabolic process


positive regulation of translation in response to endoplasmic reticulum stress


protein localization to perinuclear region of cytoplasm


regulation of alternative mRNA splicing, via spliceosome


regulation of complement activation, alternative pathway


regulation of complement activation, classical pathway


regulation of endosome to plasma membrane protein transport


TRIF-dependent toll-like receptor signaling pathway


ubiquitin-dependent protein catabolic process via the C-end degron rule pathway


cytosolic [4Fe-4S] assembly targeting complex


eukaryotic translation initiation factor 4F complex


extrinsic component of synaptic vesicle membrane


magnesium-dependent protein serine/threonine phosphatase complex


spherical high-density lipoprotein particle


acetylcholine-gated monoatomic cation-selective channel activity


calcium:monoatomic cation antiporter activity


calcium, potassium:sodium antiporter activity


ATP-dependent diacylglycerol kinase activity


G protein-coupled neurotransmitter receptor activity


G protein-coupled serotonin receptor binding


high-density lipoprotein particle binding


inhibitory MHC class I receptor activity


inositol tetrakisphosphate phosphatase activity


intracellularly cGMP-activated cation channel activity


iron ion transmembrane transporter activity


long-chain fatty acyl-CoA dehydrogenase activity


low-density lipoprotein particle binding


low-density lipoprotein particle receptor binding


mitogen-activated protein kinase kinase binding


nucleotide-sugar transmembrane transporter activity


phosphatidylinositol 3-kinase catalytic subunit binding


pyrimidine nucleotide-sugar transmembrane transporter activity


Acetylcholine binding and downstream events (Homo sapiens)


Activated NOTCH1 Transmits Signal to the Nucleus (Homo sapiens)


unsaturated fatty acid metabolic process


APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway (Homo sapiens)


Beta-catenin phosphorylation cascade (Homo sapiens)


Cargo recognition for clathrin-mediated endocytosis (Homo sapiens)


CD22 mediated BCR regulation (Homo sapiens)


Clathrin-mediated endocytosis (Homo sapiens)


Cohesin Loading onto Chromatin (Homo sapiens)


mitochondrial respiratory chain complex I assembly


Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants (Homo sapiens)


Degradation of beta-catenin by the destruction complex (Homo sapiens)


Disassembly of the destruction complex and recruitment of AXIN to the membrane (Homo sapiens)


Diseases of programmed cell death (Homo sapiens)


E2F-enabled inhibition of pre-replication complex formation (Homo sapiens)


Effects of PIP2 hydrolysis (Homo sapiens)


ERBB2 Activates PTK6 Signaling (Homo sapiens)


Erythropoietin activates Phospholipase C gamma (PLCG) (Homo sapiens)


Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (Homo sapiens)


G alpha (q) signalling events (Homo sapiens)


Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Homo sapiens)


Generation of second messenger molecules (Homo sapiens)


Golgi Associated Vesicle Biogenesis (Homo sapiens)


GRB2 events in ERBB2 signaling (Homo sapiens)


Highly calcium permeable nicotinic acetylcholine receptors (Homo sapiens)


Highly sodium permeable postsynaptic acetylcholine nicotinic receptors (Homo sapiens)


Linoleic acid (LA) metabolism (Homo sapiens)


Lysosome Vesicle Biogenesis (Homo sapiens)


MASTL Facilitates Mitotic Progression (Homo sapiens)


mitochondrial calcium ion transmembrane transport


N-Glycan antennae elongation (Homo sapiens)


NOTCH3 Activation and Transmission of Signal to the Nucleus (Homo sapiens)


NOTCH4 Activation and Transmission of Signal to the Nucleus (Homo sapiens)


NR1H2 and NR1H3-mediated signaling (Homo sapiens)


NRIF signals cell death from the nucleus (Homo sapiens)


Other semaphorin interactions (Homo sapiens)


plasma lipoprotein particle organization


Platelet sensitization by LDL (Homo sapiens)


PRC2 methylates histones and DNA (Homo sapiens)


Presynaptic nicotinic acetylcholine receptors (Homo sapiens)


PTK6 promotes HIF1A stabilization (Homo sapiens)


RAF-independent MAPK1/3 activation (Homo sapiens)


RAS signaling downstream of NF1 loss-of-function variants (Homo sapiens)


Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) (Homo sapiens)


Regulation of TP53 Expression and Degradation (Homo sapiens)


regulation of small GTPase mediated signal transduction


termination of RNA polymerase III transcription


Signaling by CTNNB1 phospho-site mutants (Homo sapiens)


Signaling by EGFR in Cancer (Homo sapiens)


Signaling by NOTCH1 HD Domain Mutants in Cancer (Homo sapiens)


Signaling by NOTCH1 PEST Domain Mutants in Cancer (Homo sapiens)


Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant (Homo sapiens)


Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)


Signaling by WNT in cancer (Homo sapiens)


Synthesis of IP3 and IP4 in the cytosol (Homo sapiens)


TCF dependent signaling in response to WNT (Homo sapiens)


Transport of nucleotide sugars (Homo sapiens)


nuclear-transcribed mRNA poly(A) tail shortening


columnar/cuboidal epithelial cell development


negative regulation of myeloid leukocyte differentiation


positive regulation of natural killer cell mediated immune response to tumor cell


regulation of heart rate by chemical signal


outer mitochondrial membrane organization


zygotic determination of anterior/posterior axis, embryo


thorax and anterior abdomen determination


embryo development ending in birth or egg hatching


regulation of mesenchymal cell proliferation


regulation of cytoplasmic mRNA processing body assembly


negative regulation of cardiac muscle adaptation


regulation of protein kinase A signaling


positive regulation of protein kinase A signaling


positive regulation of cell-substrate adhesion


skeletal muscle satellite cell activation


negative regulation of muscle hypertrophy


protein histidyl modification to diphthamide


fructose 1,6-bisphosphate metabolic process


negative regulation of telomere maintenance via telomerase


regulation of synaptic transmission, dopaminergic


positive regulation of synaptic transmission, GABAergic


regulation of intracellular lipid transport


positive regulation of intracellular lipid transport


negative regulation of transporter activity


positive regulation of ATP-dependent activity


inositol trisphosphate biosynthetic process


regulation of inositol trisphosphate biosynthetic process


positive regulation of transcription elongation by RNA polymerase II


negative regulation of intracellular steroid hormone receptor signaling pathway


regulation of intracellular estrogen receptor signaling pathway


negative regulation of tissue remodeling


negative regulation of amide metabolic process


negative regulation of transmembrane transport


negative regulation of monoatomic ion transmembrane transport


wound healing, spreading of epidermal cells


platelet-derived growth factor receptor-beta signaling pathway


modulation of process of another organism


epithelial cell differentiation involved in kidney development


response to platelet-derived growth factor


cellular response to increased oxygen levels


benzene-containing compound metabolic process


regulation of circadian sleep/wake cycle


nucleolar large rRNA transcription by RNA polymerase I


negative regulation of macrophage activation


negative regulation of potassium ion transport


response to corticotropin-releasing hormone


positive regulation of vacuole organization


regulation of cholesterol biosynthetic process


negative regulation of megakaryocyte differentiation


negative regulation of muscle contraction


negative regulation of steroid metabolic process


receptor-mediated virion attachment to host cell


negative regulation of hormone secretion


positive regulation of collateral sprouting


regulation of steroid biosynthetic process


sensory perception of temperature stimulus


disruption of plasma membrane integrity in another organism


ventricular cardiac muscle cell differentiation


regulation of dendritic spine morphogenesis


negative regulation of dendritic spine morphogenesis


cell differentiation involved in kidney development


negative regulation of cartilage development


regulation of type B pancreatic cell proliferation


proton-transporting V-type ATPase complex assembly


proton-transporting two-sector ATPase complex assembly


negative regulation of T cell apoptotic process


regulation of neuron projection regeneration


cellular response to gonadotropin stimulus


cellular response to xenobiotic stimulus


cellular response to endogenous stimulus


regulation of mononuclear cell migration


cell differentiation involved in metanephros development


metanephric nephron tubule morphogenesis


glomerular epithelial cell differentiation


positive regulation of cell migration involved in sprouting angiogenesis


receptor-mediated endocytosis involved in cholesterol transport


regulation of cholesterol metabolic process


regulation of metaphase plate congression


negative regulation of cholesterol efflux


postsynaptic actin cytoskeleton organization


regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway


positive regulation of synaptic vesicle endocytosis


regulation of phospholipase C-activating G protein-coupled receptor signaling pathway


negative regulation of hematopoietic progenitor cell differentiation


fatty acid derivative biosynthetic process


positive regulation of cell junction assembly


negative regulation of sodium ion transmembrane transport


positive regulation of stem cell population maintenance


negative regulation of protein localization to microtubule


regulation of alcohol biosynthetic process


negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding


multi-ciliated epithelial cell differentiation


positive regulation of synaptic vesicle recycling


protein localization to photoreceptor outer segment


positive regulation of protein localization to cell periphery


negative regulation of vascular associated smooth muscle cell migration


regulation of cell chemotaxis to fibroblast growth factor


regulation of stem cell population maintenance


positive regulation of reproductive process


positive regulation of cAMP-dependent protein kinase activity


regulation of platelet-derived growth factor receptor-beta signaling pathway


positive regulation of stem cell proliferation


regulation of endothelial cell chemotaxis


detection of temperature stimulus involved in sensory perception of pain


endoplasmic reticulum membrane organization


negative regulation of cell proliferation involved in heart morphogenesis


positive regulation of cholesterol metabolic process


positive regulation of collagen metabolic process


positive regulation of Golgi to plasma membrane protein transport


positive regulation of vascular wound healing


positive regulation of wound healing, spreading of epidermal cells


protein insertion into ER membrane by stop-transfer membrane-anchor sequence


protein localization to adherens junction


regulation of insulin receptor signaling pathway


regulation of post-translational protein modification


regulation of receptor-mediated endocytosis involved in cholesterol transport


satellite cell activation involved in skeletal muscle regeneration


sequestering of BMP in extracellular matrix


tail-anchored membrane protein insertion into ER membrane


vacuolar proton-transporting V-type ATPase complex assembly


extrinsic component of organelle membrane


histone pre-mRNA 3'end processing complex


nuclear outer membrane-endoplasmic reticulum membrane network


PAM complex, Tim23 associated import motor


TIM23 mitochondrial import inner membrane translocase complex


ATPase-coupled monoatomic cation transmembrane transporter activity


ATPase-coupled transmembrane transporter activity


class I DNA-(apurinic or apyrimidinic site) endonuclease activity


cytoskeleton-nuclear membrane anchor activity


RNA exonuclease activity, producing 5'-phosphomonoesters


oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor


oxidoreductase activity, acting on other nitrogenous compounds as donors


oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor


oxidoreductase activity, acting on the CH-NH2 group of donors


P-type transmembrane transporter activity


primary active transmembrane transporter activity


serine-type endopeptidase inhibitor activity


transforming growth factor beta receptor activity


transforming growth factor beta receptor activity, type I


transition metal ion transmembrane transporter activity


ubiquitin-like protein peptidase activity


Activation of anterior HOX genes in hindbrain development during early embryogenesis (Homo sapiens)


Calcitonin-like ligand receptors (Homo sapiens)


Cell-extracellular matrix interactions (Homo sapiens)


CLEC7A (Dectin-1) induces NFAT activation (Homo sapiens)


Condensation of Prometaphase Chromosomes (Homo sapiens)


Defective LFNG causes SCDO3 (Homo sapiens)


Defective RIPK1-mediated regulated necrosis (Homo sapiens)


Diseases of Base Excision Repair (Homo sapiens)


FBXW7 Mutants and NOTCH1 in Cancer (Homo sapiens)


FGFR1c ligand binding and activation (Homo sapiens)


Ligand-receptor interactions (Homo sapiens)


Maturation of spike protein (Homo sapiens)


Negative regulation of TCF-dependent signaling by DVL-interacting proteins (Homo sapiens)


Neurexins and neuroligins (Homo sapiens)


Nuclear Receptor transcription pathway (Homo sapiens)


Orexin and neuropeptides FF and QRFP bind to their respective receptors (Homo sapiens)


Phase 4 - resting membrane potential (Homo sapiens)


regulation of DNA-binding transcription factor activity


Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells (Homo sapiens)


regulation of glycolytic process through fructose-6-phosphate


Regulation of PLK1 Activity at G2/M Transition (Homo sapiens)


Reversible hydration of carbon dioxide (Homo sapiens)


RHO GTPases Activate Rhotekin and Rhophilins (Homo sapiens)


RNA Polymerase I Promoter Escape (Homo sapiens)


RUNX3 regulates YAP1-mediated transcription (Homo sapiens)


Signaling by FGFR2 IIIa TM (Homo sapiens)


Signaling by MAPK mutants (Homo sapiens)


symbiont-mediated suppression of host apoptosis


Synthesis of 15-eicosatetraenoic acid derivatives (Homo sapiens)


Synthesis of diphthamide-EEF2 (Homo sapiens)


Tandem pore domain potassium channels (Homo sapiens)


Telomere C-strand synthesis initiation (Homo sapiens)


Thrombin signalling through proteinase activated receptors (PARs) (Homo sapiens)


TP53 Regulates Transcription of Genes Involved in Cytochrome C Release (Homo sapiens)


Wax and plasmalogen biosynthesis (Homo sapiens)


WNT mediated activation of DVL (Homo sapiens)


negative regulation of transcription by RNA polymerase II


nuclear-transcribed mRNA catabolic process


negative regulation of endothelial cell proliferation


regulation of L-glutamate import across plasma membrane


regulation of myeloid leukocyte differentiation


negative regulation of B cell apoptotic process


ventricular trabecula myocardium morphogenesis


ventricular compact myocardium morphogenesis


atrial cardiac muscle tissue development


ventricular cardiac muscle tissue development


cardiac neural crest cell migration involved in outflow tract morphogenesis


regulation of secondary heart field cardioblast proliferation


apoptotic process involved in heart morphogenesis


regulation of striated muscle contraction


mitotic G2 DNA damage checkpoint signaling


cell surface receptor protein tyrosine phosphatase signaling pathway


positive regulation of cell population proliferation


aspartate family amino acid catabolic process


aromatic amino acid family catabolic process


negative regulation of biosynthetic process


positive regulation of phosphorus metabolic process


positive regulation of nuclear cell cycle DNA replication


positive regulation of platelet-derived growth factor receptor signaling pathway


cell communication by electrical coupling


regulation of cell communication by electrical coupling


regulation of epithelial to mesenchymal transition


positive regulation of myotube differentiation


cellular component assembly involved in morphogenesis


positive regulation of muscle hypertrophy


response to stimulus involved in regulation of muscle adaptation


L-tryptophan catabolic process to kynurenine


cell motility involved in cerebral cortex radial glia guided migration


positive regulation of Wnt signaling pathway


heparin proteoglycan biosynthetic process


regulation of epithelial cell differentiation


negative regulation of epithelial cell differentiation


regulatory ncRNA-mediated gene silencing


regulation of protein modification process


regulation of synaptic transmission, GABAergic


negative regulation of actin filament bundle assembly


negative regulation of gonadotropin secretion


regulation of chondrocyte differentiation


positive regulation of chondrocyte differentiation


regulation of activin receptor signaling pathway


positive regulation of peptidyl-serine phosphorylation


negative regulation of osteoblast proliferation


regulation of monoatomic ion transmembrane transport


vascular associated smooth muscle cell differentiation


negative regulation of protein import into nucleus


odontogenesis of dentin-containing tooth


positive regulation of potassium ion transport


CD8-positive, alpha-beta T cell differentiation


negative regulation of DNA-binding transcription factor activity


positive regulation by host of viral transcription


regulation of cellular component biogenesis


positive regulation of molecular function


actomyosin contractile ring organization


negative regulation of cell differentiation


positive regulation of cell differentiation


regulation of endothelial cell differentiation


regulation of osteoblast differentiation


negative regulation of smoothened signaling pathway


negative regulation of nucleobase-containing compound metabolic process


positive regulation of nucleobase-containing compound metabolic process


positive regulation of transcription by RNA polymerase II


carbon catabolite regulation of transcription


regulation of long-term neuronal synaptic plasticity


positive regulation of long-term neuronal synaptic plasticity


regulation of retinoic acid receptor signaling pathway


negative regulation of retinoic acid receptor signaling pathway


positive regulation of developmental growth


positive regulation of smooth muscle cell proliferation


embryonic cranial skeleton morphogenesis


regulation of skeletal muscle fiber development


peripheral nervous system neuron differentiation


positive regulation of epithelial cell proliferation


negative regulation of epithelial cell proliferation


regulation of peptidyl-tyrosine phosphorylation


positive regulation of peptidyl-tyrosine phosphorylation


negative regulation of synaptic transmission


positive regulation of calcium-mediated signaling


neuromuscular process controlling posture


sensory perception of mechanical stimulus


negative regulation of developmental process


regulation of muscle cell differentiation


negative regulation of muscle cell differentiation


positive regulation of muscle cell differentiation


regulation of smooth muscle cell differentiation


negative regulation of smooth muscle cell differentiation


regulation of striated muscle cell differentiation


negative regulation of striated muscle cell differentiation


positive regulation of striated muscle cell differentiation


regulation of phosphorus metabolic process


positive regulation of multicellular organismal process


positive regulation of protein metabolic process


positive regulation of RNA metabolic process


maintenance of protein location in nucleus


positive regulation of killing of cells of another organism


medium-chain fatty acid biosynthetic process


regulation of cardioblast differentiation


positive regulation of cardioblast differentiation


regulation of cardiac muscle tissue development


regulation of cardiac muscle contraction


positive regulation of cardiac muscle cell proliferation


positive regulation of glial cell proliferation


positive regulation of ryanodine-sensitive calcium-release channel activity


cardiac epithelial to mesenchymal transition


regulation of atrial cardiac muscle cell membrane depolarization


regulation of atrial cardiac muscle cell membrane repolarization


regulation of ventricular cardiac muscle cell membrane depolarization


cardiac muscle cell myoblast differentiation


branching involved in mammary gland duct morphogenesis


bud elongation involved in lung branching


cell fate specification involved in pattern specification


blood vessel endothelial cell differentiation


cell migration involved in heart development


vasculogenesis involved in coronary vascular morphogenesis


positive regulation of cell growth involved in cardiac muscle cell development


regulation of protein tyrosine kinase activity


cardiac neural crest cell differentiation involved in heart development


cardiac neural crest cell development involved in outflow tract morphogenesis


cell proliferation involved in heart morphogenesis


negative regulation of programmed necrotic cell death


negative regulation of lymphocyte apoptotic process


negative regulation of thymocyte apoptotic process


sarcoplasmic reticulum calcium ion transport


protein localization to endoplasmic reticulum exit site


cellular response to follicle-stimulating hormone stimulus


cellular response to peptide hormone stimulus


cellular response to growth hormone stimulus


cellular response to steroid hormone stimulus


cellular response to corticosteroid stimulus


cellular response to mineralocorticoid stimulus


cellular response to dexamethasone stimulus


response to transforming growth factor beta


cardiac muscle cell action potential involved in contraction


ventricular cardiac muscle cell action potential


membrane depolarization during action potential


membrane repolarization during action potential


membrane depolarization during cardiac muscle cell action potential


cell-cell signaling involved in cardiac conduction


atrial cardiac muscle cell to AV node cell signaling


bundle of His cell to Purkinje myocyte signaling


Purkinje myocyte to ventricular cardiac muscle cell signaling


membrane depolarization during AV node cell action potential


membrane depolarization during SA node cell action potential


cell communication by electrical coupling involved in cardiac conduction


cell communication involved in cardiac conduction


AV node cell to bundle of His cell communication


bundle of His cell to Purkinje myocyte communication


SA node cell to atrial cardiac muscle cell communication


regulation of heart rate by cardiac conduction


G protein-coupled receptor signaling pathway involved in heart process


regulation of transmembrane receptor protein serine/threonine kinase signaling pathway


negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway


establishment of protein localization to mitochondrial membrane


regulation of sphingolipid biosynthetic process


positive regulation of canonical Wnt signaling pathway


cell differentiation involved in phenotypic switching


response to granulocyte macrophage colony-stimulating factor


cellular response to thyroid hormone stimulus


protein localization to non-motile cilium


potassium ion export across plasma membrane


regulation of cardiac muscle cell action potential


regulation of membrane repolarization during action potential


regulation of cardiac muscle cell action potential involved in regulation of contraction


regulation of ventricular cardiac muscle cell action potential


membrane repolarization during atrial cardiac muscle cell action potential


membrane repolarization during ventricular cardiac muscle cell action potential


cardiac muscle cell membrane repolarization


regulation of cardiac muscle cell membrane repolarization


atrial cardiac muscle cell membrane repolarization


ventricular cardiac muscle cell membrane repolarization


positive regulation of calcineurin-mediated signaling


positive regulation of plasma membrane bounded cell projection assembly


positive regulation of cold-induced thermogenesis


regulation of spontaneous synaptic transmission


regulation of cellular response to hypoxia


regulation of protein localization to nucleus


positive regulation of protein localization to nucleus


negative regulation of defense response to bacterium


regulation of long-term synaptic depression


regulation of potassium ion transmembrane transporter activity


positive regulation of potassium ion transmembrane transporter activity


regulation of response to reactive oxygen species


negative regulation of trophoblast cell migration


negative regulation of potassium ion transmembrane transport


regulation of endothelial cell development


regulation of cell communication by electrical coupling involved in cardiac conduction


positive regulation of muscle tissue development


regulation of cell cycle phase transition


positive regulation of cell cycle phase transition


regulation of delayed rectifier potassium channel activity


L-alpha-amino acid transmembrane transport


positive regulation of cell cycle G1/S phase transition


regulation of actin filament-based movement


regulation of endodermal cell differentiation


protein localization to basolateral plasma membrane


release of sequestered calcium ion into cytosol by endoplasmic reticulum


negative regulation of voltage-gated potassium channel activity


regulation of cellular response to transforming growth factor beta stimulus


positive regulation of vasculature development


positive regulation of cyclin-dependent protein kinase activity


regulation of vascular associated smooth muscle cell differentiation


negative regulation of vascular associated smooth muscle cell differentiation


positive regulation of vascular associated smooth muscle cell differentiation


regulation of cardiocyte differentiation


positive regulation of cardiocyte differentiation


cellular response to insulin-like growth factor stimulus


regulation of protein localization to cell surface


negative regulation of leukocyte apoptotic process


regulation of cardiac vascular smooth muscle cell differentiation


positive regulation of stem cell differentiation


regulation of skeletal muscle cell differentiation


positive regulation of skeletal muscle cell differentiation


reactive nitrogen species metabolic process


negative regulation of chromosome organization


atrial cardiac muscle tissue morphogenesis


branched-chain amino acid biosynthetic process


cellular response to progesterone stimulus


embryonic heart tube left/right pattern formation


endocardial cushion to mesenchymal transition


endocytosis involved in viral entry into host cell


gap junction-mediated intercellular transport


medium-chain fatty acid metabolic process


membrane repolarization during cardiac muscle cell action potential


mitochondrial ADP transmembrane transport


negative regulation of ceramide biosynthetic process


negative regulation of chondrocyte proliferation


negative regulation of cyclin-dependent protein serine/threonine kinase activity


negative regulation of nitric oxide metabolic process


negative regulation of sphingolipid biosynthetic process


negative regulation of transforming growth factor beta receptor signaling pathway


positive regulation of cell adhesion molecule production


positive regulation of cellular pH reduction


positive regulation of gap junction assembly


positive regulation of leukocyte tethering or rolling


positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay


positive regulation of protein phosphorylation


protein-DNA covalent cross-linking repair


regulation of cardiac muscle cell proliferation


regulation of cell-substrate junction organization


regulation of multicellular organismal development


regulation of nitric oxide metabolic process


replication-born double-strand break repair via sister chromatid exchange


response to human chorionic gonadotropin


response to Thyroglobulin triiodothyronine


SA node cell to atrial cardiac muscle cell signaling


ventricular cardiac muscle tissue morphogenesis


endoplasmic reticulum palmitoyltransferase complex


extrinsic component of cytoplasmic side of plasma membrane


extrinsic component of endosome membrane


junctional sarcoplasmic reticulum membrane


microtubule organizing center attachment site


mitochondrial intermembrane space protein transporter complex


plasma membrane signaling receptor complex


Pwp2p-containing subcomplex of 90S preribosome


acidic amino acid transmembrane transporter activity


alcohol dehydrogenase [NAD(P)+] activity


calcium-activated potassium channel activity


cis-regulatory region sequence-specific DNA binding


collagen binding involved in cell-matrix adhesion


cyclin-dependent protein serine/threonine kinase inhibitor activity


cyclin-dependent protein serine/threonine kinase regulator activity


DNA-binding transcription activator activity


DNA-binding transcription factor activity


DNA-binding transcription factor binding


epidermal growth factor receptor binding


extracellular matrix constituent conferring elasticity


fatty acid transmembrane transporter activity


gap junction channel activity involved in cardiac conduction electrical coupling


gap junction channel activity involved in cell communication by electrical coupling


high voltage-gated calcium channel activity


insulin-like growth factor receptor binding


L-aspartate transmembrane transporter activity


L-glutamine transmembrane transporter activity


L-proline transmembrane transporter activity


NAADP-sensitive calcium-release channel activity


oleate transmembrane transporter activity


outward rectifier potassium channel activity


RNA polymerase II-specific DNA-binding transcription factor binding


single-stranded DNA endodeoxyribonuclease activity


structural molecule activity conferring elasticity


superoxide-generating NADPH oxidase activator activity


nuclear thyroid hormone receptor binding


thyroid hormone transmembrane transporter activity


transmembrane receptor protein kinase activity


transmembrane receptor protein tyrosine kinase activity


transmembrane receptor protein tyrosine kinase adaptor activity


voltage-gated potassium channel activity


voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization


voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization


Activation of NIMA Kinases NEK9, NEK6, NEK7 (Homo sapiens)


Adenylate cyclase activating pathway (Homo sapiens)


complement activation, alternative pathway


Ca2+ activated K+ channels (Homo sapiens)


Cyclin D associated events in G1 (Homo sapiens)


Cytochrome c-mediated apoptotic response (Homo sapiens)


Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)


Downregulation of ERBB2:ERBB3 signaling (Homo sapiens)


Downregulation of SMAD2/3:SMAD4 transcriptional activity (Homo sapiens)


Downstream signaling of activated FGFR2 (Homo sapiens)


Downstream signaling of activated FGFR4 (Homo sapiens)


E3 ubiquitin ligases ubiquitinate target proteins (Homo sapiens)


Early Phase of HIV Life Cycle (Homo sapiens)


Electric Transmission Across Gap Junctions (Homo sapiens)


EPHA-mediated growth cone collapse (Homo sapiens)


Estrogen-dependent nuclear events downstream of ESR-membrane signaling (Homo sapiens)


Extra-nuclear estrogen signaling (Homo sapiens)


Fcgamma receptor (FCGR) dependent phagocytosis (Homo sapiens)


FCGR3A-mediated IL10 synthesis (Homo sapiens)


FGFR2 ligand binding and activation (Homo sapiens)


FGFR2 mutant receptor activation (Homo sapiens)


FGFR2c ligand binding and activation (Homo sapiens)


FGFR3 ligand binding and activation (Homo sapiens)


FOXO-mediated transcription of cell cycle genes (Homo sapiens)


FRS-mediated FGFR2 signaling (Homo sapiens)


fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate


G-protein mediated events (Homo sapiens)


GABA B receptor activation (Homo sapiens)


Gap junction trafficking and regulation (Homo sapiens)


GP1b-IX-V activation signalling (Homo sapiens)


GRB7 events in ERBB2 signaling (Homo sapiens)


Growth hormone receptor signaling (Homo sapiens)


HDACs deacetylate histones (Homo sapiens)


Infection with Mycobacterium tuberculosis (Homo sapiens)


Loss of MECP2 binding ability to the NCoR/SMRT complex (Homo sapiens)


Lysosphingolipid and LPA receptors (Homo sapiens)


MAPK family signaling cascades (Homo sapiens)


Metal sequestration by antimicrobial proteins (Homo sapiens)


mRNA decay by 5' to 3' exoribonuclease (Homo sapiens)


Negative regulation of FGFR2 signaling (Homo sapiens)


Noncanonical activation of NOTCH3 (Homo sapiens)


NOSTRIN mediated eNOS trafficking (Homo sapiens)


Nuclear events stimulated by ALK signaling in cancer (Homo sapiens)


Oncogene Induced Senescence (Homo sapiens)


Phase 0 - rapid depolarisation (Homo sapiens)


Phase 1 - inactivation of fast Na+ channels (Homo sapiens)


Phospholipase C-mediated cascade; FGFR2 (Homo sapiens)


Platelet activation, signaling and aggregation (Homo sapiens)


Potential therapeutics for SARS (Homo sapiens)


Prolactin receptor signaling (Homo sapiens)


'de novo' post-translational protein folding


Reactions specific to the complex N-glycan synthesis pathway (Homo sapiens)


Receptor Mediated Mitophagy (Homo sapiens)


Receptor-type tyrosine-protein phosphatases (Homo sapiens)


Regulation of expression of SLITs and ROBOs (Homo sapiens)


RUNX2 regulates osteoblast differentiation (Homo sapiens)


RUNX3 regulates CDKN1A transcription (Homo sapiens)


Senescence-Associated Secretory Phenotype (SASP) (Homo sapiens)


SHC-related events triggered by IGF1R (Homo sapiens)


SHC1 events in ERBB2 signaling (Homo sapiens)


Signal transduction by L1 (Homo sapiens)


Signaling by ALK in cancer (Homo sapiens)


Signaling by CSF3 (G-CSF) (Homo sapiens)


Signaling by FGFR in disease (Homo sapiens)


Signaling by FGFR1 in disease (Homo sapiens)


Signaling by FGFR2 in disease (Homo sapiens)


Signaling by FLT3 fusion proteins (Homo sapiens)


Signaling by Nuclear Receptors (Homo sapiens)


Signaling by ROBO receptors (Homo sapiens)


mRNA 3'-end processing by stem-loop binding and cleavage


Smooth Muscle Contraction (Homo sapiens)


STAT5 activation downstream of FLT3 ITD mutants (Homo sapiens)


Tachykinin receptors bind tachykinins (Homo sapiens)


Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Homo sapiens)


Transcriptional regulation by RUNX2 (Homo sapiens)


Uptake and function of diphtheria toxin (Homo sapiens)


YAP1- and WWTR1 (TAZ)-stimulated gene expression (Homo sapiens)


branching involved in blood vessel morphogenesis


formation of translation preinitiation complex


reduction of food intake in response to dietary excess


columnar/cuboidal epithelial cell differentiation


glandular epithelial cell differentiation


CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation


regulation of carbohydrate metabolic process


'de novo' pyrimidine nucleobase biosynthetic process


termination of RNA polymerase II transcription


Wnt signaling pathway, calcium modulating pathway


glutamine family amino acid catabolic process


pyrimidine deoxyribonucleoside monophosphate biosynthetic process


negative regulation of macrophage chemotaxis


negative regulation of triglyceride biosynthetic process


positive regulation of steroid biosynthetic process


regulation of inositol phosphate biosynthetic process


pyrimidine nucleobase biosynthetic process


regulation of cerebellar granule cell precursor proliferation


endoplasmic reticulum unfolded protein response


membrane protein intracellular domain proteolysis


positive regulation of protein polymerization


positive regulation of intracellular transport


negative regulation of CREB transcription factor activity


positive regulation of natural killer cell differentiation


regulation of mast cell activation involved in immune response


regulation of peptidyl-serine phosphorylation of STAT protein


mitochondrial cytochrome c oxidase assembly


response to endoplasmic reticulum stress


intraciliary transport involved in cilium assembly


response to topologically incorrect protein


macrophage colony-stimulating factor production


single stranded viral RNA replication via double stranded DNA intermediate


negative regulation of tyrosine phosphorylation of STAT protein


amyloid precursor protein biosynthetic process


regulation of carbohydrate biosynthetic process


positive regulation of monoatomic ion transport


regulation of biological process involved in symbiotic interaction


negative regulation of cAMP-mediated signaling


establishment of epithelial cell apical/basal polarity


positive regulation of fat cell differentiation


negative regulation of carbohydrate metabolic process


positive regulation of steroid metabolic process


host-mediated suppression of symbiont invasion


phosphatidylinositol phosphate biosynthetic process


regulation of hormone biosynthetic process


hepatocyte growth factor receptor signaling pathway


determination of dorsal/ventral asymmetry


mucosa-associated lymphoid tissue development


establishment of meiotic spindle localization


positive regulation of filopodium assembly


regulation of SMAD protein signal transduction


epithelial cell proliferation involved in prostate gland development


negative regulation of epithelial cell proliferation involved in prostate gland development


establishment or maintenance of bipolar cell polarity


cell surface receptor signaling pathway involved in heart development


establishment or maintenance of monopolar cell polarity


regulation of small molecule metabolic process


positive regulation of programmed necrotic cell death


regulation of thymocyte apoptotic process


negative regulation of ERK1 and ERK2 cascade


cellular response to testosterone stimulus


granulocyte colony-stimulating factor production


positive regulation of podosome assembly


negative regulation of mesenchymal cell proliferation


pyrimidine-containing compound biosynthetic process


regulation of steroid hormone biosynthetic process


regulation of brown fat cell differentiation


positive regulation of brown fat cell differentiation


vesicle-mediated transport between endosomal compartments


regulation of postsynaptic neurotransmitter receptor activity


trans-synaptic signaling by trans-synaptic complex


regulation of actomyosin structure organization


positive regulation of vascular endothelial growth factor signaling pathway


regulation of voltage-gated calcium channel activity


regulation of hematopoietic progenitor cell differentiation


positive regulation of endothelial cell development


regulation of cell proliferation involved in kidney development


positive regulation of alcohol biosynthetic process


positive regulation of protein localization to early endosome


negative regulation of hexokinase activity


endoplasmic reticulum to cytosol transport


protein localization to cytoplasmic stress granule


regulation of phospholipid metabolic process


regulation of retrograde protein transport, ER to cytosol


regulation of protein localization to nucleolus


positive regulation of protein localization to cell cortex


regulation of protein localization to endosome


positive regulation of lipid localization


regulation of sodium-dependent phosphate transport


regulation of early endosome to late endosome transport


positive regulation of peptidyl-lysine acetylation


positive regulation of double-strand break repair


negative regulation of cation channel activity


5S class rRNA transcription by RNA polymerase III


deoxyribonucleoside monophosphate metabolic process


gamma-aminobutyric acid metabolic process


negative regulation of Golgi to plasma membrane protein transport


negative regulation of phospholipid metabolic process


positive regulation of chondrocyte proliferation


positive regulation of inositol trisphosphate biosynthetic process


positive regulation of phospholipid translocation


positive regulation of T cell mediated immune response to tumor cell


purine deoxyribonucleoside metabolic process


purine deoxyribonucleoside monophosphate catabolic process


pyrimidine nucleoside diphosphate metabolic process


pyrimidine ribonucleoside diphosphate metabolic process


regulation of collagen metabolic process


regulation of hematopoietic stem cell differentiation


regulation of phospholipid translocation


regulation of transcription of nucleolar large rRNA by RNA polymerase I


COPII-coated ER to Golgi transport vesicle


lumenal side of endoplasmic reticulum membrane


phosphatidylinositol 3-kinase complex, class I


phosphatidylinositol 3-kinase complex, class IA


amino acid:monoatomic cation symporter activity


androstan-3-alpha,17-beta-diol dehydrogenase (NAD+) activity


cyclin-dependent protein serine/threonine kinase activator activity


extracellular ligand-gated monoatomic ion channel activity


fibroblast growth factor receptor activity


G protein-coupled amine receptor activity


histone H3K9me2/H3K9me3 demethylase activity


hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines


inositol 1,3,4,5 tetrakisphosphate binding


L-arginine transmembrane transporter activity


ligase activity, forming carbon-nitrogen bonds


MAP kinase tyrosine/serine/threonine phosphatase activity


neurotransmitter receptor regulator activity


nitric-oxide synthase regulator activity


oxidoreductase activity, acting on a heme group of donors


protein serine/threonine phosphatase activity


protein tyrosine/serine/threonine phosphatase activity


transmembrane receptor protein serine/threonine kinase activity


ubiquitin-protein transferase inhibitor activity


Activated NTRK3 signals through PI3K (Homo sapiens)


Assembly of active LPL and LIPC lipase complexes (Homo sapiens)


Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA (Homo sapiens)


Cargo trafficking to the periciliary membrane (Homo sapiens)


Caspase-mediated cleavage of cytoskeletal proteins (Homo sapiens)


ChREBP activates metabolic gene expression (Homo sapiens)


CLEC7A/inflammasome pathway (Homo sapiens)


CREB3 factors activate genes (Homo sapiens)


DNA Double Strand Break Response (Homo sapiens)


FLT3 signaling by CBL mutants (Homo sapiens)


G-protein beta:gamma signalling (Homo sapiens)


Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation (Homo sapiens)


InlA-mediated entry of Listeria monocytogenes into host cells (Homo sapiens)


Interleukin-12 family signaling (Homo sapiens)


MET activates PI3K/AKT signaling (Homo sapiens)


MET interacts with TNS proteins (Homo sapiens)


Metabolic disorders of biological oxidation enzymes (Homo sapiens)


Negative regulation of MET activity (Homo sapiens)


positive regulation of epidermal growth factor receptor signaling pathway


Regulation of KIT signaling (Homo sapiens)


Regulation of signaling by CBL (Homo sapiens)


Response of Mtb to phagocytosis (Homo sapiens)


Scavenging of heme from plasma (Homo sapiens)


Sensory perception of salty taste (Homo sapiens)


Sensory processing of sound (Homo sapiens)


Sensory processing of sound by outer hair cells of the cochlea (Homo sapiens)


Signaling by Interleukins (Homo sapiens)


Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Homo sapiens)


Synthesis of pyrophosphates in the cytosol (Homo sapiens)


Transcriptional Regulation by TP53 (Homo sapiens)


Unfolded Protein Response (UPR) (Homo sapiens)


VEGFR2 mediated vascular permeability (Homo sapiens)


Vitamin B2 (riboflavin) metabolism (Homo sapiens)


sleep apnea measurement during non-REM sleep


negative regulation of cell-matrix adhesion


columnar/cuboidal epithelial cell maturation


regulation of antimicrobial humoral response


regulation of acute inflammatory response to antigenic stimulus


regulation of extracellular matrix constituent secretion


post-translational protein targeting to endoplasmic reticulum membrane


activation of NF-kappaB-inducing kinase activity


vascular endothelial growth factor production


positive regulation of vascular endothelial growth factor production


negative regulation of fibroblast migration


negative regulation of tumor necrosis factor-mediated signaling pathway


positive regulation of lipoprotein particle clearance


positive regulation of glutamate secretion


anaphase-promoting complex-dependent catabolic process


axon ensheathment in central nervous system


negative regulation of intracellular transport


late endosome to vacuole transport via multivesicular body sorting pathway


negative regulation of ATP-dependent activity


negative regulation of amine metabolic process


nucleoside bisphosphate metabolic process


nucleoside bisphosphate biosynthetic process


regulation of toll-like receptor 3 signaling pathway


positive regulation of toll-like receptor 3 signaling pathway


long-chain fatty-acyl-CoA metabolic process


long-chain fatty-acyl-CoA biosynthetic process


purinergic nucleotide receptor signaling pathway


regulation of cytoplasmic pattern recognition receptor signaling pathway


negative regulation of cytoplasmic pattern recognition receptor signaling pathway


negative regulation of RIG-I signaling pathway


regulation of glial cell differentiation


positive regulation of circadian sleep/wake cycle, sleep


negative regulation of striated muscle contraction


negative regulation of fatty acid oxidation


regulation of lipid biosynthetic process


negative regulation of fibroblast proliferation


negative regulation of developmental growth


chondroitin sulfate proteoglycan biosynthetic process


negative regulation of defense response to virus


chromosome movement towards spindle pole


regulation of nervous system development


positive regulation of nervous system development


negative regulation of synaptic transmission, glutamatergic


positive regulation of growth hormone secretion


branching involved in salivary gland morphogenesis


epithelial cell proliferation involved in lung morphogenesis


intestinal epithelial cell differentiation


multicellular organismal-level iron ion homeostasis


epithelial cell proliferation involved in salivary gland morphogenesis


mesenchymal cell proliferation involved in lung development


tRNA aminoacylation for mitochondrial protein translation


neutrophil-mediated killing of gram-negative bacterium


cellular response to electrical stimulus


negative regulation of monocyte chemotactic protein-1 production


positive regulation of glomerular mesangial cell proliferation


purine-containing compound metabolic process


purine-containing compound biosynthetic process


establishment of protein localization to endoplasmic reticulum


establishment of protein localization to vacuole


negative regulation of protein targeting to membrane


negative regulation of intracellular protein transport


establishment of endothelial intestinal barrier


postsynaptic neurotransmitter receptor internalization


presynaptic dense core vesicle exocytosis


regulation of calcineurin-mediated signaling


aminoacyl-tRNA metabolism involved in translational fidelity


regulation of protein K63-linked ubiquitination


negative regulation of protein K63-linked ubiquitination


carbohydrate derivative metabolic process


positive regulation of neutrophil migration


negative regulation of cell cycle G1/S phase transition


negative regulation of protein polyubiquitination


negative regulation of proteolysis involved in protein catabolic process


regulation of protein localization to cell cortex


positive regulation of metallopeptidase activity


positive regulation of vascular associated smooth muscle cell apoptotic process


regulation of binding of sperm to zona pellucida


regulation of interleukin-1-mediated signaling pathway


negative regulation of interleukin-1-mediated signaling pathway


regulation of epithelial cell proliferation involved in lung morphogenesis


cellular response to oxygen-glucose deprivation


dermatan sulfate proteoglycan metabolic process


ligand-gated ion channel signaling pathway


negative regulation of cell-substrate junction organization


negative regulation of fibroblast growth factor production


negative regulation of mitotic cell cycle phase transition


positive regulation of antibacterial peptide production


positive regulation of extracellular matrix constituent secretion


positive regulation of immature T cell proliferation


regulation of anaphase-promoting complex-dependent catabolic process


regulation of hemoglobin biosynthetic process


regulation of immature T cell proliferation


regulation of intestinal lipid absorption


regulation of tetrapyrrole metabolic process


L-type voltage-gated calcium channel complex


17-beta-hydroxysteroid dehydrogenase (NAD+) activity


copper ion transmembrane transporter activity


crossover junction DNA endonuclease activity


DNA endonuclease activity, producing 3'-phosphomonoesters


extracellularly ATP-gated monoatomic cation channel activity


G protein-coupled adenosine receptor activity


G protein-coupled glutamate receptor binding


glycerol transmembrane transporter activity


glycine transmembrane transporter activity


hydrolase activity, acting on ester bonds


hydrolase activity, acting on glycosyl bonds


inorganic molecular entity transmembrane transporter activity


monoatomic ion transmembrane transporter activity


kainate selective glutamate receptor activity


ligase activity, forming carbon-sulfur bonds


medium-chain fatty acid-CoA ligase activity


non-membrane spanning protein tyrosine kinase activity


oxidoreductase activity, acting on CH-OH group of donors


oxidoreductase activity, acting on metal ions, oxygen as acceptor


oxidoreductase activity, acting on the CH-CH group of donors


oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor


polyol transmembrane transporter activity


protein-arginine omega-N monomethyltransferase activity


pyruvate dehydrogenase (acetyl-transferring) kinase activity


RNA polymerase III general transcription initiation factor activity


sulfur amino acid transmembrane transporter activity


type 5 metabotropic glutamate receptor binding


ubiquitin-like modifier activating enzyme activity


Activation of the phototransduction cascade (Homo sapiens)


Activation of TRKA receptors (Homo sapiens)


Apoptotic factor-mediated response (Homo sapiens)


Beta oxidation of butanoyl-CoA to acetyl-CoA (Homo sapiens)


Beta oxidation of hexanoyl-CoA to butanoyl-CoA (Homo sapiens)


Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA (Homo sapiens)


Beta oxidation of octanoyl-CoA to hexanoyl-CoA (Homo sapiens)


Cargo concentration in the ER (Homo sapiens)


G2/M DNA damage checkpoint (Homo sapiens)


Glutamate Neurotransmitter Release Cycle (Homo sapiens)


double-strand break repair via homologous recombination


Hormone ligand-binding receptors (Homo sapiens)


Ionotropic activity of kainate receptors (Homo sapiens)


MET promotes cell motility (Homo sapiens)


mitochondrial fatty acid beta-oxidation of unsaturated fatty acids (Homo sapiens)


N-glycan trimming in the ER and Calnexin/Calreticulin cycle (Homo sapiens)


activation of adenylate cyclase activity


Nitric oxide stimulates guanylate cyclase (Homo sapiens)


Olfactory Signaling Pathway (Homo sapiens)


PI3K events in ERBB2 signaling (Homo sapiens)


PKA-mediated phosphorylation of key metabolic factors (Homo sapiens)


Processing of DNA double-strand break ends (Homo sapiens)


Regulation of PTEN gene transcription (Homo sapiens)


regulation of signal transduction by p53 class mediator


Regulation of TP53 Activity through Phosphorylation (Homo sapiens)


Serotonin Neurotransmitter Release Cycle (Homo sapiens)


SUMOylation of immune response proteins (Homo sapiens)


SUMOylation of transcription factors (Homo sapiens)


Termination of translesion DNA synthesis (Homo sapiens)


TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway (Homo sapiens)


TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest (Homo sapiens)


sleep apnea measurement during REM sleep