3-phosphoinositide dependent protein kinase 1


ABL proto-oncogene 1, non-receptor tyrosine kinase


ABL proto-oncogene 2, non-receptor tyrosine kinase


acyl-CoA synthetase short chain family member 2


advanced glycosylation end-product specific receptor


aldehyde dehydrogenase 5 family member A1


compound 8 [Avgoustou <i>et al</i>., 2020]


A-Raf proto-oncogene, serine/threonine kinase


ATP-binding cassette, sub-family C (CFTR/MRP), member 8


5-butyl-methyl immidazole carboxylate 30


compound 1 [Cruz-López <i>et al</i>., 2019]


gastrin releasing peptide(14-27) (human)


hydroxyethylamine transition-state inhibitor 1


BLK proto-oncogene, Src family tyrosine kinase


bone morphogenetic protein receptor type 2


bone morphogenetic protein receptor type IA


bone morphogenetic protein receptor type IB


B-Raf proto-oncogene, serine/threonine kinase


branched chain amino acid transaminase 1


branched chain amino acid transaminase 2


bromodomain adjacent to zinc finger domain 2A


bromodomain adjacent to zinc finger domain 2B


bromodomain PHD finger transcription factor


BUB1 mitotic checkpoint serine/threonine kinase


calcium/calmodulin dependent protein kinase ID


calcium/calmodulin-dependent protein kinase II alpha subunit


calcium/calmodulin-dependent protein kinase II beta subunit


calcium/calmodulin-dependent protein kinase II delta subunit


calcium/calmodulin-dependent protein kinase II gamma subunit


calcium/calmodulin dependent protein kinase kinase 1


calcium/calmodulin dependent protein kinase kinase 2


calcium/calmodulin dependent serine protein kinase


casein kinase 2, alpha 1 polypeptide subunit


casein kinase 2, alpha prime polypeptide subunit


caseinolytic mitochondrial matrix peptidase proteolytic subunit


CD20 (membrane-spanning 4-domains, subfamily A, member 1)


citron rho-interacting serine/threonine kinase


coactivator associated arginine methyltransferase 1


component of inhibitor of nuclear factor kappa B kinase complex


compound 4b [Ramsey <i>et al</i>., 2023]


c-ros oncogene 1, receptor tyrosine kinase


cytokine domain of tyrosyl tRNA synthetase


compound 51 [Mallinger <i>et al</i>., 2016]


compound 20 [Bergeron <i>et al</i>., 2016]


compound 51 [Crosignani <i>et al.</i>, 2011]


cytotoxic T-lymphocyte-associated protein 4 (CD152)


discoidin domain receptor tyrosine kinase 1


discoidin domain receptor tyrosine kinase 2


Dopamine beta-hydroxylase (dopamine beta-monooxygenase)


DOT1 like histone lysine methyltransferase


dual specificity tyrosine phosphorylation regulated kinase 1A


dual specificity tyrosine phosphorylation regulated kinase 1B


dual specificity tyrosine phosphorylation regulated kinase 2


dual specificity tyrosine phosphorylation regulated kinase 3


dual specificity tyrosine phosphorylation regulated kinase 4


ectonucleoside triphosphate diphosphohydrolase 1


ectonucleoside triphosphate diphosphohydrolase 2


endogenous retrovirus group W member 1, envelope


endoplasmic reticulum to nucleus signaling 1


enhancer of zeste 1 polycomb repressive complex 2 subunit


enhancer of zeste 2 polycomb repressive complex 2 subunit


euchromatic histone lysine methyltransferase 1


euchromatic histone lysine methyltransferase 2


eukaryotic translation initiation factor 2 alpha kinase 1


eukaryotic translation initiation factor 2 alpha kinase 2


eukaryotic translation initiation factor 2 alpha kinase 3


eukaryotic translation initiation factor 2 alpha kinase 4


farnesyltransferase, CAAX box, subunit beta


Fc fragment of IgG receptor and transporter


FGR proto-oncogene, Src family tyrosine kinase


VEGF receptor tyrosine kinase inhibitor III


Folate hydrolase (prostate-specific membrane antigen) 1


furin, paired basic amino acid cleaving enzyme


FYN proto-oncogene, Src family tyrosine kinase


Granulocyte colony-stimulating factor receptor


Granulocyte macrophage colony-stimulating factor receptor


HCK proto-oncogene, Src family tyrosine kinase


heat shock protein 90 alpha family class A member 1


heat shock protein 90 alpha family class B member 1


heat shock protein 90 beta family member 1


heat shock protein family A (Hsp70) member 1A


compound 23f [Zhang <i>et al</i>., 2025]


homeodomain interacting protein kinase 1


homeodomain interacting protein kinase 2


homeodomain interacting protein kinase 3


hormonally up-regulated Neu-associated kinase


compound 4 [Balasubramanian <i>et al.</i>, 1992]


derivative 17 [Nakahata <i>et al</i>., 2018]


compound 3a [Badolato <i>et al</i>., 2019]


example 494 [WO2014028479] parent molecule


[125I]angiotensin-(1-7) (human, mouse, rat)


inhibitor of nuclear factor kappa B kinase subunit beta


inhibitor of nuclear factor kappa B kinase subunit epsilon


integrin, alpha 4 subunit (antigen CD49D, alpha 4 subunit of VLA-4 receptor)


integrin, alpha 5 subunit (fibronectin receptor, alpha polypeptide)


integrin, alpha L subunit (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)


integrin, beta 1 subunit (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)


integrin, beta 2 subunit (complement component 3 receptor 3 and 4 subunit)


integrin, beta 3 subunit (platelet glycoprotein IIIa, antigen CD61)


interleukin 1 receptor associated kinase 1


interleukin 1 receptor associated kinase 3


interleukin 1 receptor associated kinase 4


killer cell lectin like receptor C1 (CD159a)


VEGF receptor tyrosine kinase inhibitor II


KIT proto-oncogene, receptor tyrosine kinase


L3MBTL histone methyl-lysine binding protein 3


compound 1 [Gotteland <i>et al</i>., 1997]


compound 4a [Marquart <i>et al.</i>, 1994]


compound 4b [Marquart <i>et al.</i>, 1994]


LCK proto-oncogene, Src family tyrosine kinase


leucine rich repeat and Ig domain containing 1


leukocyte immunoglobulin like receptor A4 (CD85g)


LYN proto-oncogene, Src family tyrosine kinase


MAPK interacting serine/threonine kinase 1


MAPK interacting serine/threonine kinase 2


maternal embryonic leucine zipper kinase


MCL1 apoptosis regulator, BCL2 family member


membrane bound transcription factor peptidase, site 1


methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit


MET proto-oncogene, receptor tyrosine kinase


microtubule affinity regulating kinase 1


microtubule affinity regulating kinase 2


microtubule affinity regulating kinase 3


microtubule affinity regulating kinase 4


Microtubule associated serine/threonine kinase 3


Mitochondrial adenine nucleotide translocator 1


mitogen-activated protein kinase kinase 1


mitogen-activated protein kinase kinase 2


mitogen-activated protein kinase kinase 3


mitogen-activated protein kinase kinase 4


mitogen-activated protein kinase kinase 5


mitogen-activated protein kinase kinase 6


mitogen-activated protein kinase kinase 7


mitogen-activated protein kinase kinase kinase 1


mitogen-activated protein kinase kinase kinase 10


mitogen-activated protein kinase kinase kinase 11


mitogen-activated protein kinase kinase kinase 12


mitogen-activated protein kinase kinase kinase 13


mitogen-activated protein kinase kinase kinase 14


compound 3a [Pipionne <i>et al</i>, 2018]


mitogen-activated protein kinase kinase kinase 19


mitogen-activated protein kinase kinase kinase 2


mitogen-activated protein kinase kinase kinase 3


mitogen-activated protein kinase kinase kinase 5


mitogen-activated protein kinase kinase kinase 6


mitogen-activated protein kinase kinase kinase 7


mitogen-activated protein kinase kinase kinase 8


mitogen-activated protein kinase kinase kinase 9


mitogen-activated protein kinase kinase kinase kinase 1


mitogen-activated protein kinase kinase kinase kinase 2


mitogen-activated protein kinase kinase kinase kinase 3


mitogen-activated protein kinase kinase kinase kinase 4


mitogen-activated protein kinase kinase kinase kinase 5


mixed lineage kinase domain like pseudokinase


muscle associated receptor tyrosine kinase


myosin light chain kinase family member 4


compound 5 [Stecula <i>et al</i>., 2020]


NAD(P) dependent 3-beta-hydroxysteroid dehydrogenase NSDHL


Natural cytotoxicity triggering receptor 3 (CD337)


Natural cytotoxicity triggering receptor 3 ligand 1


nicotinic acetylcholine receptor α10 subunit


nicotinic acetylcholine receptor α1 subunit


nicotinic acetylcholine receptor α2 subunit


nicotinic acetylcholine receptor α3 subunit


nicotinic acetylcholine receptor α4 subunit


nicotinic acetylcholine receptor α5 subunit


nicotinic acetylcholine receptor α6 subunit


nicotinic acetylcholine receptor α7 subunit


nicotinic acetylcholine receptor α9 subunit


nicotinic acetylcholine receptor δ subunit


NPC1 like intracellular cholesterol transporter 1


nuclear receptor binding SET domain protein 1


nuclear receptor binding SET domain protein 2


compound 29 [Vietor, <i>et al</i>., 2023]


nucleotide binding oligomerization domain containing 1


nucleotide binding oligomerization domain containing 2


Oncostatin M-specific receptor, β subunit


CRAC channel inhibitor 1 [PMID: 26256403]


CRAC channel inhibitor 5b [PMID: 26256403]


OTU deubiquitinase, ubiquitin aldehyde binding 1


GlaxoSmithKline compound 5h [PMID:20542694]


GlaxoSmithKline compound 6i [PMID:18926700]


2-furoyl-LIGRL[N-(Alexa Fluor 594)-O]-NH<sub>2 </sub>


PAS domain containing serine/threonine kinase


patatin like domain 2, triacylglycerol lipase


peptidylprolyl cis/trans isomerase, NIMA-interacting 1


phosphatidylinositol 3-kinase catalytic subunit type 3


phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha


phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta


phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta


phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma


phosphatidylinositol 4-kinase type 2 alpha


phosphatidylinositol 4-kinase type 2 beta


phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha


phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta


phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma


phosphatidylinositol-4-phosphate 5-kinase type 1 alpha


phosphatidylinositol-5-phosphate 4-kinase type 2 alpha


compound 29 [Moslin <i>et al</i>., 2017]


phosphoinositide kinase, FYVE-type zinc finger containing


phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase


phosphorylase kinase catalytic subunit gamma 1


phosphorylase kinase catalytic subunit gamma 2


Pim-1 proto-oncogene, serine/threonine kinase


Pim-2 proto-oncogene, serine/threonine kinase


Pim-3 proto-oncogene, serine/threonine kinase


platelet derived growth factor receptor alpha


PDGF receptor tyrosine kinase inhibitor II


platelet derived growth factor receptor beta


PDGF receptor tyrosine kinase inhibitor III


PDGF receptor tyrosine kinase inhibitor IV


compound 5 [Tomassi <i>et al</i>., 2020]


poly(ADP-ribose) polymerase family member 10


poly(ADP-ribose) polymerase family member 11


poly(ADP-ribose) polymerase family member 14


poly(ADP-ribose) polymerase family member 15


chorionic somatomammotropin hormone-like 1


proprotein convertase subtilisin/kexin type 1


proprotein convertase subtilisin/kexin type 2


proprotein convertase subtilisin/kexin type 4


proprotein convertase subtilisin/kexin type 5


proprotein convertase subtilisin/kexin type 6


proprotein convertase subtilisin/kexin type 7


proprotein convertase subtilisin/kexin type 9


protein C, inactivator of coagulation factors Va and VIIIa


protein disulfide isomerase family A member 3


protein kinase AMP-activated non-catalytic subunit beta 1


protein kinase AMP-activated non-catalytic subunit beta 2


protein kinase, cAMP-dependent, catalytic, alpha subunit


protein kinase, cAMP-dependent, catalytic, beta subunit


protein kinase, DNA-activated, catalytic subunit


allosteric modulator 33 [PMID: 35878399]


protein kinase, membrane associated tyrosine/threonine 1


protein phosphatase 1 catalytic subunit alpha


protein phosphatase 2 catalytic subunit alpha


protein phosphatase, Mg2+/Mn2+ dependent 1D


protein tyrosine phosphatase non-receptor type 1


compound 7b [Haftchenary <i>et al.</i>, 2013]


protein tyrosine phosphatase non-receptor type 11


protein tyrosine phosphatase non-receptor type 2


protein tyrosine phosphatase non-receptor type 22


Raf-1 proto-oncogene, serine/threonine kinase


Rap guanine nucleotide exchange factor 3


Rap guanine nucleotide exchange factor 4


compound 14 [Schnute <i>et al</i>., 2023]


RORC2 inverse agonist 66 [PMID: 30130103]


receptor interacting serine/threonine kinase 1


receptor interacting serine/threonine kinase 2


receptor interacting serine/threonine kinase 3


repulsive guidance molecule BMP co-receptor a


compound 28 [Heitel <i>et al</i>., 2019]


Rho associated coiled-coil containing protein kinase 1


Rho associated coiled-coil containing protein kinase 2


ribonucleotide reductase catalytic subunit M1


ribonucleotide reductase regulatory subunit M2


europium-labelled relaxin-3-B/INSL5 A chimera


SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1


serine palmitoyltransferase long chain base subunit 1


serine palmitoyltransferase long chain base subunit 2


serine palmitoyltransferase long chain base subunit 3


serine palmitoyltransferase small subunit B


serum/glucocorticoid regulated kinase family member 3


SET domain containing 7, histone lysine methyltransferase


sigma non-opioid intracellular receptor 1


signal transducer and activator of transcription 3


signal transducer and activator of transcription 5A


signal transducer and activator of transcription 6


SMG1 nonsense mediated mRNA decay associated PI3K related kinase


Sodium/bile acid and sulphated solute cotransporter 1


Sodium/bile acid and sulphated solute cotransporter 2


Sodium-dependent vitamin C transporter 1


sodium/potassium-transporting ATPase subunit α-1


SOS Ras/Rac guanine nucleotide exchange factor 1


SPNS lysolipid transporter 2, sphingosine-1-phosphate


compound 12 [Wattanasin <i>et al.,</i>1997]


compound 15 [Biller <i>et al.</i>, 1993]


compound 16a [Sharratt <i>et al.</i>, 1994]


compound 17 [Shechter <i>et al</i>., 1996]


compound 1 [Overhand <i>et al</i>., 1997]


compound 20 [Shechter <i>et al</i>., 1996]


compound 4 [Brinkman <i>et al</i>., 1996]


compound 7 [Brinkman <i>et al</i>., 1996]


compound 8 [Brinkman <i>et al</i>., 1996]


SRC proto-oncogene, non-receptor tyrosine kinase


src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites


ST14 transmembrane serine protease matriptase


inhibitor 1 [Colombo <i>et al.</i>, 2012]


stimulator of interferon response cGAMP interactor 1


STIP1 homology and U-box containing protein 1


SUMO peptidase family member, NEDD8 specific


SUV39H1 histone lysine methyltransferase


SUV39H2 histone lysine methyltransferase


SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2


SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4


TATA-box binding protein associated factor 1


TCDD inducible poly(ADP-ribose) polymerase


testis associated actin remodelling kinase 1


testis associated actin remodelling kinase 2


compound 12p [Larson <i>et al.</i>, 2017]


phosphatidyl (3,5) inositol bisphosphate


transforming growth factor beta receptor 1


transforming growth factor beta receptor 2


triggering receptor expressed on myeloid cells 2


Pyrazolo-pyrimidine 14a [PMID: 29859875]


pentafluoro-trityl clotrimazole analogue 29a


tumor associated calcium signal transducer 2


tyrosine kinase with immunoglobulin like and EGF like domains 1


UDP glucuronosyltransferase family 1 member A1


unc-51 like autophagy activating kinase 1


unc-51 like autophagy activating kinase 2


Vesicular inhibitory amino acid transporter


vitamin K epoxide reductase complex subunit 1


YES proto-oncogene 1, Src family tyrosine kinase


YTH N6-methyladenosine RNA binding protein C1


ZAK sterile alpha motif and leucine zipper containing kinase AZK


zeta chain of T cell receptor associated protein kinase 70


mucosal addressin cell adhesion molecule 1